FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0436, 364 aa 1>>>pF1KE0436 364 - 364 aa - 364 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5501+/-0.000927; mu= 15.0064+/- 0.056 mean_var=67.5649+/-13.642, 0's: 0 Z-trim(105.2): 25 B-trim: 49 in 1/50 Lambda= 0.156032 statistics sampled from 8279 (8290) to 8279 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.255), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS34796.1 AGPAT5 gene_id:55326|Hs108|chr8 ( 364) 2447 559.9 1.2e-159 CCDS42670.1 LCLAT1 gene_id:253558|Hs108|chr2 ( 376) 387 96.2 4.9e-20 CCDS1772.1 LCLAT1 gene_id:253558|Hs108|chr2 ( 414) 387 96.2 5.3e-20 CCDS13703.1 AGPAT3 gene_id:56894|Hs108|chr21 ( 376) 307 78.2 1.3e-14 CCDS5280.1 AGPAT4 gene_id:56895|Hs108|chr6 ( 378) 261 67.8 1.7e-11 >>CCDS34796.1 AGPAT5 gene_id:55326|Hs108|chr8 (364 aa) initn: 2447 init1: 2447 opt: 2447 Z-score: 2979.6 bits: 559.9 E(32554): 1.2e-159 Smith-Waterman score: 2447; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KE0 MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 PERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWIYGTLLGCLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWIYGTLLGCLWV 310 320 330 340 350 360 pF1KE0 TIKA :::: CCDS34 TIKA >>CCDS42670.1 LCLAT1 gene_id:253558|Hs108|chr2 (376 aa) initn: 297 init1: 209 opt: 387 Z-score: 473.2 bits: 96.2 E(32554): 4.9e-20 Smith-Waterman score: 403; 28.5% identity (58.0% similar) in 295 aa overlap (30-312:13-294) 10 20 30 40 50 pF1KE0 MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWR----LLSAFLPARF-----YQALD : :: . .:: ::: : :. .. CCDS42 MVSWKGIYFILTLFWGSFFGSIFMLSPFLPLMFVNPSWYRWIN 10 20 30 40 60 70 80 90 100 110 pF1KE0 DRLYCVYQSMVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNA .:: .. .. . ..:.. ::.... :: : . . ::.. .::. .: . CCDS42 NRLVATWLTLPVALLETMFGVKVIITGDAFVPGERSVIIMNHRTRMDWMFLWNCLMRYSY 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 LGHVRYVLKEGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIF : . :: .:: .: .: . . :...:. : ....... .. . : :. :.:: CCDS42 LRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMIDYFCDIHEPLQLLIF 110 120 130 140 150 160 180 190 200 210 220 pF1KE0 PEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKN--YLDAIYDVT :::: . :..: : :.::: . :: ..:: :: . . : ... :::..:.: CCDS42 PEGTDLT-ENSK--SRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDIT 170 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 VVYEGKDDGGQRRESPTMTEFLCKECPK-IHIHIDRIDKKDVPEEQEHMRRWLHERFEIK :.: . .... .: . :. ::.:. : .: .: .. : :.:.: : CCDS42 VAYPHNIPQSEKH-------LLQGDFPREIHFHVHRYPIDTLPTSKEDLQLWCHKRWEEK 230 240 250 260 270 290 300 310 320 330 340 pF1KE0 DKMLIEFYESPDPERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNT .. : ::.. :. : :.:: CCDS42 EERLRSFYQG---EKNFYFTGQSVIPPCKSELRVLVVKLLSILYWTLFSPAMCLLIYLYS 280 290 300 310 320 330 >>CCDS1772.1 LCLAT1 gene_id:253558|Hs108|chr2 (414 aa) initn: 297 init1: 209 opt: 387 Z-score: 472.5 bits: 96.2 E(32554): 5.3e-20 Smith-Waterman score: 403; 28.5% identity (58.0% similar) in 295 aa overlap (30-312:51-332) 10 20 30 40 50 pF1KE0 MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWR----LLSAFLPARF-----YQAL : :: . .:: ::: : :. . CCDS17 VSSYCTYFIKQDSKSFGIMVSWKGIYFILTLFWGSFFGSIFMLSPFLPLMFVNPSWYRWI 30 40 50 60 70 80 60 70 80 90 100 110 pF1KE0 DDRLYCVYQSMVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQN ..:: .. .. . ..:.. ::.... :: : . . ::.. .::. .: . CCDS17 NNRLVATWLTLPVALLETMFGVKVIITGDAFVPGERSVIIMNHRTRMDWMFLWNCLMRYS 90 100 110 120 130 140 120 130 140 150 160 170 pF1KE0 ALGHVRYVLKEGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVI : . :: .:: .: .: . . :...:. : ....... .. . : :. :.: CCDS17 YLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMIDYFCDIHEPLQLLI 150 160 170 180 190 200 180 190 200 210 220 pF1KE0 FPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKN--YLDAIYDV ::::: . :..: : :.::: . :: ..:: :: . . : ... :::..:. CCDS17 FPEGTDLT-ENSK--SRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDI 210 220 230 240 250 230 240 250 260 270 280 pF1KE0 TVVYEGKDDGGQRRESPTMTEFLCKECPK-IHIHIDRIDKKDVPEEQEHMRRWLHERFEI ::.: . .... .: . :. ::.:. : .: .: .. : :.:.: CCDS17 TVAYPHNIPQSEKH-------LLQGDFPREIHFHVHRYPIDTLPTSKEDLQLWCHKRWEE 260 270 280 290 300 310 290 300 310 320 330 340 pF1KE0 KDKMLIEFYESPDPERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVN :.. : ::.. :. : :.:: CCDS17 KEERLRSFYQG---EKNFYFTGQSVIPPCKSELRVLVVKLLSILYWTLFSPAMCLLIYLY 320 330 340 350 360 >>CCDS13703.1 AGPAT3 gene_id:56894|Hs108|chr21 (376 aa) initn: 265 init1: 128 opt: 307 Z-score: 375.9 bits: 78.2 E(32554): 1.3e-14 Smith-Waterman score: 314; 25.4% identity (58.5% similar) in 272 aa overlap (45-310:44-297) 20 30 40 50 60 70 pF1KE0 LLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQSMVLFFFENYTGVQI ..:. :. :: :......: .. .. CCDS13 HLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTEC 20 30 40 50 60 70 80 90 100 110 120 130 pF1KE0 LLYGDLPK----NKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLKEGLKWLPLYG :. : .::. . . ::. .:.. . . : ..:: . . :. : ..:: : CCDS13 TLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIG 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 C--YFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPEQTKVLSAS :: . .. ::. . .. . . :. : :..... ::::.. . .: : CCDS13 WTWYFLEI--VFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRFTETKHRV---S 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQRRESPTMT . :: .:: :::. : :: :. .: :... . :.::::. ..:. ..:.. CCDS13 MEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGN-------KNPSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPDPERRKRFP .: . . . . :. .:.: .... .:::. .. :: : :.: ... :: CCDS13 GILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDA-LQEIY-----NQKGMFP 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 GKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWIYGTLLGCLWVTIKA :. CCDS13 GEQFKPARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRL 300 310 320 330 340 350 >>CCDS5280.1 AGPAT4 gene_id:56895|Hs108|chr6 (378 aa) initn: 221 init1: 131 opt: 261 Z-score: 319.9 bits: 67.8 E(32554): 1.7e-11 Smith-Waterman score: 350; 25.0% identity (58.6% similar) in 324 aa overlap (1-313:1-310) 10 20 30 40 50 pF1KE0 MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRL-YCVYQ : :. .:.. . .:. :..... . . .. :: . .... .. :: ::. . CCDS52 MDLAGLLKSQFLCHLVFCYVFIASG-LIINTIQLFTLLLWPINKQLFRKINCRLSYCISS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 SMVLFFFENYTGVQILLYGD----LPKNKENIIYLANHQSTVDWIVADILAIRQNALGHV ..:... : ..:.. .. : : .::: : . ::. .:.. . :. : . :: CCDS52 QLVMLL-EWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 RYVLKEGLKWLPLYGC--YFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPE . . :. : ..:. : ::.. .. .:. . ..: . ..:: : ....: : CCDS52 KVLAKKELAYVPIIGWMWYFTEM--VFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYE :::.. .. .. :. : .:: ::: : :: :. .. ..: ..:.:: :. .. CCDS52 GTRFTEKKHEI---SMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 GKDDGGQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLI .. :.::. : . . ... :: .:.::.... :::. .. :: . CCDS52 NN-------ENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQE 240 250 260 270 280 300 310 320 330 340 pF1KE0 EFYES---PD-PERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTW :.:.. :. : : : :: CCDS52 EYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFF 290 300 310 320 330 340 364 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:06:14 2016 done: Thu Nov 3 09:06:14 2016 Total Scan time: 2.230 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]