FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0439, 314 aa 1>>>pF1KE0439 314 - 314 aa - 314 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3512+/-0.000423; mu= 15.1809+/- 0.026 mean_var=64.9604+/-12.835, 0's: 0 Z-trim(110.3): 23 B-trim: 0 in 0/54 Lambda= 0.159129 statistics sampled from 18641 (18657) to 18641 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.219), width: 16 Scan time: 6.480 The best scores are: opt bits E(85289) NP_005318 (OMIM: 231530,601609,609975) hydroxyacyl ( 314) 1986 465.0 8.8e-131 NP_001317956 (OMIM: 231530,601609,609975) hydroxya ( 318) 1729 406.0 5.1e-113 NP_001171634 (OMIM: 231530,601609,609975) hydroxya ( 331) 1451 342.2 8.7e-94 NP_000173 (OMIM: 600890,609015,609016) trifunction ( 763) 548 135.1 4.5e-31 XP_006713588 (OMIM: 607037,615605) PREDICTED: pero ( 515) 441 110.4 8e-24 XP_016861328 (OMIM: 607037,615605) PREDICTED: pero ( 515) 441 110.4 8e-24 XP_011510819 (OMIM: 607037,615605) PREDICTED: pero ( 627) 441 110.5 9.4e-24 NP_001159887 (OMIM: 607037,615605) peroxisomal bif ( 627) 441 110.5 9.4e-24 NP_001957 (OMIM: 607037,615605) peroxisomal bifunc ( 723) 441 110.5 1.1e-23 NP_057058 (OMIM: 609877) lambda-crystallin homolog ( 319) 307 79.5 9.7e-15 XP_005266473 (OMIM: 609877) PREDICTED: lambda-crys ( 217) 255 67.5 2.7e-11 XP_016876113 (OMIM: 609877) PREDICTED: lambda-crys ( 234) 234 62.7 8.2e-10 XP_005266472 (OMIM: 609877) PREDICTED: lambda-crys ( 265) 184 51.3 2.6e-06 >>NP_005318 (OMIM: 231530,601609,609975) hydroxyacyl-coe (314 aa) initn: 1986 init1: 1986 opt: 1986 Z-score: 2468.9 bits: 465.0 E(85289): 8.8e-131 Smith-Waterman score: 1986; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314) 10 20 30 40 50 60 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN 250 260 270 280 290 300 310 pF1KE0 KFGKKTGEGFYKYK :::::::::::::: NP_005 KFGKKTGEGFYKYK 310 >>NP_001317956 (OMIM: 231530,601609,609975) hydroxyacyl- (318 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 2150.0 bits: 406.0 E(85289): 5.1e-113 Smith-Waterman score: 1729; 98.5% identity (99.3% similar) in 275 aa overlap (40-314:44-318) 10 20 30 40 50 60 pF1KE0 RSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG : . .::::::::::::::::::::::::: NP_001 LGVCWRKEHDPAEMLRVGRAELGGWKPSWEAIVKEVAAATGHTVVLVDQTEDILAKSKKG 20 30 40 50 60 70 70 80 90 100 110 120 pF1KE0 IEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE0 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT 140 150 160 170 180 190 190 200 210 220 230 240 pF1KE0 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK 200 210 220 230 240 250 250 260 270 280 290 300 pF1KE0 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG 260 270 280 290 300 310 310 pF1KE0 FYKYK ::::: NP_001 FYKYK >>NP_001171634 (OMIM: 231530,601609,609975) hydroxyacyl- (331 aa) initn: 1450 init1: 1450 opt: 1451 Z-score: 1804.8 bits: 342.2 E(85289): 8.7e-94 Smith-Waterman score: 1942; 94.9% identity (94.9% similar) in 331 aa overlap (1-314:1-331) 10 20 30 40 50 60 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERDFQT 190 200 210 220 230 240 240 250 260 270 280 pF1KE0 -------------GDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAE ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGDSNSGLGFSLKGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAE 250 260 270 280 290 300 290 300 310 pF1KE0 NPLHQPSPSLNKLVAENKFGKKTGEGFYKYK ::::::::::::::::::::::::::::::: NP_001 NPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 310 320 330 >>NP_000173 (OMIM: 600890,609015,609016) trifunctional e (763 aa) initn: 380 init1: 252 opt: 548 Z-score: 678.9 bits: 135.1 E(85289): 4.5e-31 Smith-Waterman score: 548; 34.1% identity (66.2% similar) in 290 aa overlap (27-314:361-640) 10 20 30 40 50 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLV :::....:.::::::::::.. : ..: NP_000 VMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILK 340 350 360 370 380 390 60 70 80 90 100 110 pF1KE0 DQTEDILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLV : : : .... . ..: .::: : : . .. . :. . ...:.: NP_000 DATLTALDRGQQQVFKGLNDKVKKK------ALTSFERDSIFSNLTGQLDYQGFEKADMV 400 410 420 430 440 120 130 140 150 160 170 pF1KE0 VEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVP .::. :.:..:....:... .: :::::::.: :. :: .. : .. :.:.:.:: NP_000 IEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVD 450 460 470 480 490 500 180 190 200 210 220 230 pF1KE0 VMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER :.:.:.: : ::. : : : . :: . :: ::: ..: :.:.. :.::. .. NP_000 KMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQE 510 520 530 540 550 560 240 250 260 270 280 290 pF1KE0 G-DASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSL-N : : .: : .. . :.:.: :.: ::.:..: ... .. .: . .: : . NP_000 GVDPKKLD---SLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGER-FGGGNPELLT 570 580 590 600 610 620 300 310 pF1KE0 KLVAENKFGKKTGEGFYKYK ..:... .:.:.:.::: :. NP_000 QMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTR 630 640 650 660 670 680 >>XP_006713588 (OMIM: 607037,615605) PREDICTED: peroxiso (515 aa) initn: 468 init1: 286 opt: 441 Z-score: 548.7 bits: 110.4 E(85289): 8e-24 Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:77-374) 10 20 30 40 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI :..: .:::. :. : :.: : :: :: XP_006 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI 50 60 70 80 90 100 50 60 70 80 90 100 pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA . : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :.. XP_006 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK 110 120 130 140 150 160 110 120 130 140 150 160 pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT . ..:::.::. :....:...: .:. .... .:::.:.. ::..: XP_006 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD 170 180 190 200 210 170 180 190 200 210 220 pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR : : :::.:. ::::.::: . ..: :. .....:: . : : . ::. :: XP_006 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR 220 230 240 250 260 270 230 240 250 260 270 pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT .: :: .: : :.: .. :..: ... :. ::::.. : .::: : XP_006 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG 280 290 300 310 320 330 280 290 300 310 pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK .. : : . : :.. : ..::.:::.:.:.: XP_006 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF 340 350 360 370 380 390 XP_006 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH 400 410 420 430 440 450 >>XP_016861328 (OMIM: 607037,615605) PREDICTED: peroxiso (515 aa) initn: 468 init1: 286 opt: 441 Z-score: 548.7 bits: 110.4 E(85289): 8e-24 Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:77-374) 10 20 30 40 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI :..: .:::. :. : :.: : :: :: XP_016 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI 50 60 70 80 90 100 50 60 70 80 90 100 pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA . : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :.. XP_016 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK 110 120 130 140 150 160 110 120 130 140 150 160 pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT . ..:::.::. :....:...: .:. .... .:::.:.. ::..: XP_016 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD 170 180 190 200 210 170 180 190 200 210 220 pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR : : :::.:. ::::.::: . ..: :. .....:: . : : . ::. :: XP_016 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR 220 230 240 250 260 270 230 240 250 260 270 pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT .: :: .: : :.: .. :..: ... :. ::::.. : .::: : XP_016 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG 280 290 300 310 320 330 280 290 300 310 pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK .. : : . : :.. : ..::.:::.:.:.: XP_016 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF 340 350 360 370 380 390 XP_016 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH 400 410 420 430 440 450 >>XP_011510819 (OMIM: 607037,615605) PREDICTED: peroxiso (627 aa) initn: 468 init1: 286 opt: 441 Z-score: 547.4 bits: 110.5 E(85289): 9.4e-24 Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:189-486) 10 20 30 40 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI :..: .:::. :. : :.: : :: :: XP_011 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI 160 170 180 190 200 210 50 60 70 80 90 100 pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA . : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :.. XP_011 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK 220 230 240 250 260 270 110 120 130 140 150 160 pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT . ..:::.::. :....:...: .:. .... .:::.:.. ::..: XP_011 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD 280 290 300 310 320 170 180 190 200 210 220 pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR : : :::.:. ::::.::: . ..: :. .....:: . : : . ::. :: XP_011 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR 330 340 350 360 370 380 230 240 250 260 270 pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT .: :: .: : :.: .. :..: ... :. ::::.. : .::: : XP_011 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG 390 400 410 420 430 440 280 290 300 310 pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK .. : : . : :.. : ..::.:::.:.:.: XP_011 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF 450 460 470 480 490 500 XP_011 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH 510 520 530 540 550 560 >>NP_001159887 (OMIM: 607037,615605) peroxisomal bifunct (627 aa) initn: 468 init1: 286 opt: 441 Z-score: 547.4 bits: 110.5 E(85289): 9.4e-24 Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:189-486) 10 20 30 40 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI :..: .:::. :. : :.: : :: :: NP_001 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI 160 170 180 190 200 210 50 60 70 80 90 100 pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA . : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :.. NP_001 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK 220 230 240 250 260 270 110 120 130 140 150 160 pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT . ..:::.::. :....:...: .:. .... .:::.:.. ::..: NP_001 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD 280 290 300 310 320 170 180 190 200 210 220 pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR : : :::.:. ::::.::: . ..: :. .....:: . : : . ::. :: NP_001 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR 330 340 350 360 370 380 230 240 250 260 270 pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT .: :: .: : :.: .. :..: ... :. ::::.. : .::: : NP_001 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG 390 400 410 420 430 440 280 290 300 310 pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK .. : : . : :.. : ..::.:::.:.:.: NP_001 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF 450 460 470 480 490 500 NP_001 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH 510 520 530 540 550 560 >>NP_001957 (OMIM: 607037,615605) peroxisomal bifunction (723 aa) initn: 468 init1: 286 opt: 441 Z-score: 546.5 bits: 110.5 E(85289): 1.1e-23 Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:285-582) 10 20 30 40 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI :..: .:::. :. : :.: : :: :: NP_001 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI 260 270 280 290 300 310 50 60 70 80 90 100 pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA . : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :.. NP_001 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK 320 330 340 350 360 370 110 120 130 140 150 160 pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT . ..:::.::. :....:...: .:. .... .:::.:.. ::..: NP_001 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD 380 390 400 410 420 170 180 190 200 210 220 pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR : : :::.:. ::::.::: . ..: :. .....:: . : : . ::. :: NP_001 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR 430 440 450 460 470 480 230 240 250 260 270 pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT .: :: .: : :.: .. :..: ... :. ::::.. : .::: : NP_001 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG 490 500 510 520 530 540 280 290 300 310 pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK .. : : . : :.. : ..::.:::.:.:.: NP_001 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF 550 560 570 580 590 NP_001 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH 600 610 620 630 640 650 >>NP_057058 (OMIM: 609877) lambda-crystallin homolog [Ho (319 aa) initn: 238 init1: 150 opt: 307 Z-score: 385.6 bits: 79.5 E(85289): 9.7e-15 Smith-Waterman score: 307; 28.3% identity (59.1% similar) in 237 aa overlap (30-262:9-241) 10 20 30 40 50 60 pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE :...:.:..: . :.. :. : : : : NP_057 MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYD--- 10 20 30 70 80 90 100 110 120 pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI : .. .. :..:: : . :. ::. :: :. . .:... . : . NP_057 -IEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL :.:..:...: .::.. ...:..:.:: :. ... . .. . : :: . : NP_057 PEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPL 100 110 120 130 140 150 190 200 210 220 230 pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDA ::.. : :. : . . : .:. :. :.. ::..::: . :: :: :.: . NP_057 VELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIV 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 SKEDIDTAMKLGAGYP---MGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKL : :.: .:. : :. .::.: . NP_057 SPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRA 220 230 240 250 260 270 314 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:54:35 2016 done: Thu Nov 3 08:54:36 2016 Total Scan time: 6.480 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]