FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0440, 306 aa 1>>>pF1KE0440 306 - 306 aa - 306 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5268+/-0.000814; mu= 14.5604+/- 0.049 mean_var=65.5190+/-13.130, 0's: 0 Z-trim(107.7): 18 B-trim: 43 in 1/49 Lambda= 0.158449 statistics sampled from 9725 (9734) to 9725 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.299), width: 16 Scan time: 2.090 The best scores are: opt bits E(32554) CCDS43338.1 LYSMD3 gene_id:116068|Hs108|chr5 ( 306) 2019 470.1 9.6e-133 CCDS68911.1 LYSMD3 gene_id:116068|Hs108|chr5 ( 127) 571 138.9 1.9e-33 CCDS66877.1 LYSMD4 gene_id:145748|Hs108|chr15 ( 296) 301 77.3 1.6e-14 >>CCDS43338.1 LYSMD3 gene_id:116068|Hs108|chr5 (306 aa) initn: 2019 init1: 2019 opt: 2019 Z-score: 2496.7 bits: 470.1 E(32554): 9.6e-133 Smith-Waterman score: 2019; 99.7% identity (99.7% similar) in 306 aa overlap (1-306:1-306) 10 20 30 40 50 60 pF1KE0 MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LCPPKGRQTSRHSSVQYSSEQQEILPANDSLAYSDSAGSFLKEVDRDIEQIVKCTDNKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LCPPKGRQTSRHSSVQYSSEQQEILPANDSLAYSDSAGSFLKEVDRDIEQIVKCTDNKRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 AILAKVDVSHHSTVDSSHLHSKITPPSQQREMENGIVPTKGIHFSQQDDHKLYSQDSQSP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EILAKVDVSHHSTVDSSHLHSKITPPSQQREMENGIVPTKGIHFSQQDDHKLYSQDSQSP 250 260 270 280 290 300 pF1KE0 AAQQET :::::: CCDS43 AAQQET >>CCDS68911.1 LYSMD3 gene_id:116068|Hs108|chr5 (127 aa) initn: 571 init1: 571 opt: 571 Z-score: 713.8 bits: 138.9 E(32554): 1.9e-33 Smith-Waterman score: 571; 100.0% identity (100.0% similar) in 86 aa overlap (1-86:1-86) 10 20 30 40 50 60 pF1KE0 MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTET :::::::::::::::::::::::::: CCDS68 DIIVLTKDIQEGDTLNAIALQYCCTVYQNSSKKVQFLDRNTLSSKRKTDFTSFICSILFR 70 80 90 100 110 120 >>CCDS66877.1 LYSMD4 gene_id:145748|Hs108|chr15 (296 aa) initn: 384 init1: 202 opt: 301 Z-score: 374.4 bits: 77.3 E(32554): 1.6e-14 Smith-Waterman score: 437; 34.8% identity (60.2% similar) in 299 aa overlap (4-286:2-290) 10 20 30 40 50 pF1KE0 MAGRHQN---RSFPLPGV---QSSGQVHAFGNCS-DS-DILEEDAEVYELRSRGKEKVRR ::.. ..: :.: ...:. : : : :: : ::... :: ::::. . CCDS66 MRHEELLTKTFQGPAVVCGTPTSHVYMFKNGSGDSGDSSEEESHRVVLRPRGKERHKS 10 20 30 40 50 60 70 80 90 100 pF1KE0 STSRDRL---DDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKI .. . :...: ... . :.:: .:::: : :::::.:::.: .::..::.:.:: CCDS66 GVHQPPQAGAGDVVLLQRELAQEDSLNKLALQYGCKVADIKKVNNFIREQDLYALKSVKI 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 PVKKFSSLTETLCPPKGRQTSRHSSVQYSSEQQEILPANDSL-AYSDSAGSFLKEVDRDI ::.. . : :: : : : . . : : :. . : . . .:.: .:.:: CCDS66 PVRNHGILMETHKELKP-LLSPSSETTVTVELPEADRAGAGTGAQAGQLMGFFKGIDQDI 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 EQIVKCTDNKRENLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIV :. :. .. :.: :..: . : . : :. ::: :: ::.:: :::.. CCDS66 ERAVQ----SEIFLHESYCMDTSHQP-LLP----APPKTPMDGADCGIQWWNAVFIMLLI 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 GIITPVFYLLYYAILAKVDV--SHHSTVDSSHLHSKITPPSQQREMENGI--VPTKGIHF ::. :::::.:. : :. .. : ..:: . . : :.: .. .. : . .: CCDS66 GIVLPVFYLVYFKIQASGETPNSLNTTVIPNGSMAMGTVPGQAPRLAVAVPAVTSADSQF 230 240 250 260 270 280 290 300 pF1KE0 SQQDDHKLYSQDSQSPAAQQET :: CCDS66 SQTTQAGS 290 306 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:52:13 2016 done: Thu Nov 3 08:52:13 2016 Total Scan time: 2.090 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]