FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0442, 323 aa 1>>>pF1KE0442 323 - 323 aa - 323 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5743+/-0.000956; mu= 14.4690+/- 0.057 mean_var=66.2033+/-13.195, 0's: 0 Z-trim(103.7): 17 B-trim: 0 in 0/50 Lambda= 0.157628 statistics sampled from 7542 (7551) to 7542 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.232), width: 16 Scan time: 2.380 The best scores are: opt bits E(32554) CCDS1688.1 FAM49A gene_id:81553|Hs108|chr2 ( 323) 2119 490.9 5.8e-139 CCDS6361.1 FAM49B gene_id:51571|Hs108|chr8 ( 324) 1682 391.5 4.8e-109 CCDS83327.1 FAM49B gene_id:51571|Hs108|chr8 ( 178) 995 235.2 3e-62 >>CCDS1688.1 FAM49A gene_id:81553|Hs108|chr2 (323 aa) initn: 2119 init1: 2119 opt: 2119 Z-score: 2608.3 bits: 490.9 E(32554): 5.8e-139 Smith-Waterman score: 2119; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323) 10 20 30 40 50 60 pF1KE0 MGNLLKVLTREIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILADLQAYKGAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MGNLLKVLTREIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILADLQAYKGAGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 EIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 LEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 EMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 SRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLN 250 260 270 280 290 300 310 320 pF1KE0 ALRFTTKHLNDESTSKQIRAMLQ ::::::::::::::::::::::: CCDS16 ALRFTTKHLNDESTSKQIRAMLQ 310 320 >>CCDS6361.1 FAM49B gene_id:51571|Hs108|chr8 (324 aa) initn: 1681 init1: 1642 opt: 1682 Z-score: 2071.2 bits: 391.5 E(32554): 4.8e-109 Smith-Waterman score: 1682; 79.3% identity (92.9% similar) in 324 aa overlap (1-323:1-324) 10 20 30 40 50 pF1KE0 MGNLLKVLT-REIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILADLQAYKGAG ::::::::: ..:. :.::::::::::::.:.::.::...::.:.:.:: :::.:.::: CCDS63 MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 PEIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQ :::.:::.: : .::::::.:: ::: .::.::::: ::: ::..:: .:: ::.::: CCDS63 HEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 HLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVN ::::::::::.:::::::::::::::: ::::::::::::::.:: ::::. . ::::: CCDS63 HLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 NEMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEY ::.:::::::::::::::::::.:: .::::::.:::::::::::::.:::.:::::::: CCDS63 NELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 RSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLL :::::.:::. ::.::::::::::::::::::: :::::::::::::::.: :.:::::: CCDS63 RSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLL 250 260 270 280 290 300 300 310 320 pF1KE0 NALRFTTKHLNDESTSKQIRAMLQ ::::.::::::::.:::::..::: CCDS63 NALRYTTKHLNDETTSKQIKSMLQ 310 320 >>CCDS83327.1 FAM49B gene_id:51571|Hs108|chr8 (178 aa) initn: 995 init1: 995 opt: 995 Z-score: 1231.0 bits: 235.2 E(32554): 3e-62 Smith-Waterman score: 995; 84.8% identity (94.9% similar) in 178 aa overlap (146-323:1-178) 120 130 140 150 160 170 pF1KE0 TPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIE : ::::::::::::::.:: ::::. . : CCDS83 MTNPAIQNDFSYYRRTLSRMRINNVPAEGE 10 20 30 180 190 200 210 220 230 pF1KE0 NEVNNEMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLE ::::::.:::::::::::::::::::.:: .::::::.:::::::::::::.:::.:::: CCDS83 NEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLE 40 50 60 70 80 90 240 250 260 270 280 290 pF1KE0 TPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSV :::::::::.:::. ::.::::::::::::::::::: :::::::::::::::.: :.:: CCDS83 TPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSV 100 110 120 130 140 150 300 310 320 pF1KE0 EGLLNALRFTTKHLNDESTSKQIRAMLQ ::::::::.::::::::.:::::..::: CCDS83 EGLLNALRYTTKHLNDETTSKQIKSMLQ 160 170 323 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:40:03 2016 done: Thu Nov 3 08:40:04 2016 Total Scan time: 2.380 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]