FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0444, 277 aa 1>>>pF1KE0444 277 - 277 aa - 277 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6022+/-0.000375; mu= 10.2395+/- 0.023 mean_var=115.4479+/-23.453, 0's: 0 Z-trim(116.5): 3 B-trim: 1081 in 1/54 Lambda= 0.119366 statistics sampled from 27783 (27786) to 27783 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.326), width: 16 Scan time: 7.520 The best scores are: opt bits E(85289) NP_878272 (OMIM: 608249) E3 ubiquitin-protein liga ( 277) 1851 329.3 4.9e-90 NP_878269 (OMIM: 608249) E3 ubiquitin-protein liga ( 277) 1851 329.3 4.9e-90 NP_067001 (OMIM: 608249) E3 ubiquitin-protein liga ( 277) 1851 329.3 4.9e-90 >>NP_878272 (OMIM: 608249) E3 ubiquitin-protein ligase C (277 aa) initn: 1851 init1: 1851 opt: 1851 Z-score: 1737.4 bits: 329.3 E(85289): 4.9e-90 Smith-Waterman score: 1851; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KE0 MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA 190 200 210 220 230 240 250 260 270 pF1KE0 GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI ::::::::::::::::::::::::::::::::::::: NP_878 GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI 250 260 270 >>NP_878269 (OMIM: 608249) E3 ubiquitin-protein ligase C (277 aa) initn: 1851 init1: 1851 opt: 1851 Z-score: 1737.4 bits: 329.3 E(85289): 4.9e-90 Smith-Waterman score: 1851; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KE0 MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA 190 200 210 220 230 240 250 260 270 pF1KE0 GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI ::::::::::::::::::::::::::::::::::::: NP_878 GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI 250 260 270 >>NP_067001 (OMIM: 608249) E3 ubiquitin-protein ligase C (277 aa) initn: 1851 init1: 1851 opt: 1851 Z-score: 1737.4 bits: 329.3 E(85289): 4.9e-90 Smith-Waterman score: 1851; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KE0 MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA 190 200 210 220 230 240 250 260 270 pF1KE0 GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI ::::::::::::::::::::::::::::::::::::: NP_067 GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI 250 260 270 277 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:37:17 2016 done: Thu Nov 3 08:37:18 2016 Total Scan time: 7.520 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]