FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0447, 175 aa
1>>>pF1KE0447 175 - 175 aa - 175 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0697+/-0.000621; mu= 14.4142+/- 0.038
mean_var=65.0184+/-13.199, 0's: 0 Z-trim(111.2): 14 B-trim: 0 in 0/51
Lambda= 0.159058
statistics sampled from 12191 (12205) to 12191 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.375), width: 16
Scan time: 1.970
The best scores are: opt bits E(32554)
CCDS8351.1 CRYAB gene_id:1410|Hs108|chr11 ( 175) 1196 282.3 1.1e-76
CCDS81626.1 CRYAB gene_id:1410|Hs108|chr11 ( 108) 708 170.2 3.7e-43
CCDS82651.1 LOC102724652 gene_id:102724652|Hs108|c ( 173) 657 158.6 1.8e-39
CCDS13695.1 CRYAA gene_id:1409|Hs108|chr21 ( 173) 657 158.6 1.8e-39
CCDS12475.1 HSPB6 gene_id:126393|Hs108|chr19 ( 160) 480 118.0 2.8e-27
CCDS82652.1 LOC102724652 gene_id:102724652|Hs108|c ( 136) 434 107.4 3.7e-24
CCDS5583.1 HSPB1 gene_id:3315|Hs108|chr7 ( 205) 384 96.0 1.5e-20
CCDS8352.1 HSPB2 gene_id:3316|Hs108|chr11 ( 182) 381 95.3 2.2e-20
CCDS9189.1 HSPB8 gene_id:26353|Hs108|chr12 ( 196) 245 64.1 5.7e-11
>>CCDS8351.1 CRYAB gene_id:1410|Hs108|chr11 (175 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1490.5 bits: 282.3 E(32554): 1.1e-76
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>CCDS81626.1 CRYAB gene_id:1410|Hs108|chr11 (108 aa)
initn: 708 init1: 708 opt: 708 Z-score: 888.4 bits: 170.2 E(32554): 3.7e-43
Smith-Waterman score: 708; 100.0% identity (100.0% similar) in 108 aa overlap (68-175:1-108)
40 50 60 70 80 90
pF1KE0 FPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDV
::::::::::::::::::::::::::::::
CCDS81 MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
10 20 30
100 110 120 130 140 150
pF1KE0 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPER
40 50 60 70 80 90
160 170
pF1KE0 TIPITREEKPAVTAAPKK
::::::::::::::::::
CCDS81 TIPITREEKPAVTAAPKK
100
>>CCDS82651.1 LOC102724652 gene_id:102724652|Hs108|chr21 (173 aa)
initn: 504 init1: 406 opt: 657 Z-score: 822.2 bits: 158.6 E(32554): 1.8e-39
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-173:1-171)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
CCDS82 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
CCDS82 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
CCDS82 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
120 130 140 150 160 170
>>CCDS13695.1 CRYAA gene_id:1409|Hs108|chr21 (173 aa)
initn: 504 init1: 406 opt: 657 Z-score: 822.2 bits: 158.6 E(32554): 1.8e-39
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-173:1-171)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
CCDS13 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
CCDS13 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
CCDS13 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
120 130 140 150 160 170
>>CCDS12475.1 HSPB6 gene_id:126393|Hs108|chr19 (160 aa)
initn: 478 init1: 345 opt: 480 Z-score: 603.1 bits: 118.0 E(32554): 2.8e-27
Smith-Waterman score: 480; 46.5% identity (73.6% similar) in 159 aa overlap (1-155:3-154)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRR---PFFPFHSPSRLFDQFFGEHLLESDLFPTS-TSLSPFYLRPPSF
. . .. :.:: :. . .:.::::: ::: :::..: :.:.:.::: ::
CCDS12 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPS-
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFI
. : .... . .::: ::::::::::. :::.:. .:::..:::: :::::.
CCDS12 VALP------VAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPK
.:::::.::.: ::: ..::.:: .:::.... ....:
CCDS12 AREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK
120 130 140 150 160
pF1KE0 K
>>CCDS82652.1 LOC102724652 gene_id:102724652|Hs108|chr21 (136 aa)
initn: 417 init1: 347 opt: 434 Z-score: 547.1 bits: 107.4 E(32554): 3.7e-24
Smith-Waterman score: 434; 52.3% identity (75.0% similar) in 128 aa overlap (50-173:10-134)
20 30 40 50 60 70
pF1KE0 PSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNL
:::. : : ..: ..:.: . :
CCDS82 MPVCPGDSHRPPKALPHLVCGRRG-RQVRSDRDKFVIFL
10 20 30
80 90 100 110 120 130
pF1KE0 DVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSS
::::::::.: ::: : .:.::::.::::.::.:::::::.::.:..:: ... :::.
CCDS82 DVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSA
40 50 60 70 80 90
140 150 160 170
pF1KE0 DGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
::.:: ::. :. . ::.::..::::: :.::
CCDS82 DGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
100 110 120 130
>>CCDS5583.1 HSPB1 gene_id:3315|Hs108|chr7 (205 aa)
initn: 444 init1: 349 opt: 384 Z-score: 482.5 bits: 96.0 E(32554): 1.5e-20
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (13-166:18-188)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
:: .. :::::: :: : . . : : :.::
CCDS55 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
10 20 30 40 50 60
60 70 80 90 100
pF1KE0 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
:.. :: : ...:.::.: ::. :.:::.::.:.:: ::. :.:.
CCDS55 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
70 80 90 100 110 120
110 120 130 140 150
pF1KE0 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
:::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... . : :
CCDS55 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
130 140 150 160 170 180
160 170
pF1KE0 IPITREEKPAVTAAPKK
::.: : .
CCDS55 IPVTFESRAQLGGPEAAKSDETAAK
190 200
>>CCDS8352.1 HSPB2 gene_id:3316|Hs108|chr11 (182 aa)
initn: 358 init1: 310 opt: 381 Z-score: 479.6 bits: 95.3 E(32554): 2.2e-20
Smith-Waterman score: 381; 43.1% identity (72.3% similar) in 137 aa overlap (15-149:16-148)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPS
. : .:::: .: ::: :: ... : : .:.:: . ::.
CCDS83 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEIL-TPTLYHGYYVRPRA---APA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 WFDT--GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISRE
. : ::.:: . .:.. :::.::.:.:. :... ...:: ..: .: :.:::.:::
CCDS83 GEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSRE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 FHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
: : : .:::::: . ..:: ::.:....::
CCDS83 FCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEE
120 130 140 150 160 170
CCDS83 AAIVEP
180
>>CCDS9189.1 HSPB8 gene_id:26353|Hs108|chr12 (196 aa)
initn: 273 init1: 224 opt: 245 Z-score: 310.4 bits: 64.1 E(32554): 5.7e-11
Smith-Waterman score: 284; 35.2% identity (61.2% similar) in 165 aa overlap (1-149:6-170)
10 20 30 40
pF1KE0 MDIAIHHP-WIRR-PFFPFHSPSRLFDQFFGEHLLESDL--------FPTSTSLS
: .. :.: .:: :: :::.:. :: . .:: .: .:
CCDS91 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
10 20 30 40 50 60
50 60 70 80 90
pF1KE0 PFYLRPPSFLRAPSW---FDT---GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIE
: :: :.:. : . : . . . ..: ..:. :.:::: ::. .:
CCDS91 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 VHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTI
: :::::.:.: :..:..: .: ..::.:::.:. .::: .:.: ...:.
CCDS91 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
130 140 150 160 170 180
160 170
pF1KE0 PITREEKPAVTAAPKK
CCDS91 SFNNELPQDSQEVTCT
190
175 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:20:10 2016 done: Thu Nov 3 08:20:10 2016
Total Scan time: 1.970 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]