Result of FASTA (omim) for
pF1KE0447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0447, 175 aa
1>>>pF1KE0447 175 - 175 aa - 175 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0878+/-0.000289; mu= 14.2635+/- 0.018
mean_var=62.3049+/-12.637, 0's: 0 Z-trim(118.4): 21 B-trim: 1530 in 1/56
Lambda= 0.162485
statistics sampled from 31259 (31280) to 31259 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.367), width: 16
Scan time: 5.650
The best scores are: opt bits E(85289)
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175) 1196 288.0 5.1e-78
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175) 1196 288.0 5.1e-78
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175) 1196 288.0 5.1e-78
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175) 1196 288.0 5.1e-78
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108) 708 173.5 9.4e-44
NP_000385 (OMIM: 123580,604219) alpha-crystallin A ( 173) 657 161.7 5.5e-40
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160) 480 120.2 1.6e-27
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136) 434 109.4 2.4e-24
NP_001531 (OMIM: 602195,606595,608634) heat shock ( 205) 384 97.7 1.2e-20
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182) 381 97.0 1.7e-20
NP_055180 (OMIM: 158590,608014,608673) heat shock ( 196) 245 65.1 7.2e-11
NP_006299 (OMIM: 604624,613376) heat shock protein ( 150) 200 54.5 8.6e-08
XP_011539552 (OMIM: 610692) PREDICTED: heat shock ( 262) 181 50.2 3e-06
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170) 178 49.4 3.4e-06
XP_011539551 (OMIM: 610692) PREDICTED: heat shock ( 263) 176 49.0 6.8e-06
NP_149971 (OMIM: 608344) heat shock protein beta-9 ( 159) 147 42.1 0.0005
>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1521.7 bits: 288.0 E(85289): 5.1e-78
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a (175 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1521.7 bits: 288.0 E(85289): 5.1e-78
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1521.7 bits: 288.0 E(85289): 5.1e-78
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1521.7 bits: 288.0 E(85289): 5.1e-78
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_001317308 (OMIM: 123590,608810,613763,613869,615184 (108 aa)
initn: 708 init1: 708 opt: 708 Z-score: 906.5 bits: 173.5 E(85289): 9.4e-44
Smith-Waterman score: 708; 100.0% identity (100.0% similar) in 108 aa overlap (68-175:1-108)
40 50 60 70 80 90
pF1KE0 FPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDV
::::::::::::::::::::::::::::::
NP_001 MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
10 20 30
100 110 120 130 140 150
pF1KE0 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPER
40 50 60 70 80 90
160 170
pF1KE0 TIPITREEKPAVTAAPKK
::::::::::::::::::
NP_001 TIPITREEKPAVTAAPKK
100
>>NP_000385 (OMIM: 123580,604219) alpha-crystallin A cha (173 aa)
initn: 504 init1: 406 opt: 657 Z-score: 838.9 bits: 161.7 E(85289): 5.5e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-173:1-171)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
NP_000 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
NP_000 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
NP_000 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
120 130 140 150 160 170
>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho (160 aa)
initn: 478 init1: 345 opt: 480 Z-score: 615.1 bits: 120.2 E(85289): 1.6e-27
Smith-Waterman score: 480; 46.5% identity (73.6% similar) in 159 aa overlap (1-155:3-154)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRR---PFFPFHSPSRLFDQFFGEHLLESDLFPTS-TSLSPFYLRPPSF
. . .. :.:: :. . .:.::::: ::: :::..: :.:.:.::: ::
NP_653 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPS-
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFI
. : .... . .::: ::::::::::. :::.:. .:::..:::: :::::.
NP_653 VALP------VAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPK
.:::::.::.: ::: ..::.:: .:::.... ....:
NP_653 AREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK
120 130 140 150 160
pF1KE0 K
>>XP_005261150 (OMIM: 123580,604219) PREDICTED: alpha-cr (136 aa)
initn: 417 init1: 347 opt: 434 Z-score: 557.9 bits: 109.4 E(85289): 2.4e-24
Smith-Waterman score: 434; 52.3% identity (75.0% similar) in 128 aa overlap (50-173:10-134)
20 30 40 50 60 70
pF1KE0 PSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNL
:::. : : ..: ..:.: . :
XP_005 MPVCPGDSHRPPKALPHLVCGRRG-RQVRSDRDKFVIFL
10 20 30
80 90 100 110 120 130
pF1KE0 DVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSS
::::::::.: ::: : .:.::::.::::.::.:::::::.::.:..:: ... :::.
XP_005 DVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSA
40 50 60 70 80 90
140 150 160 170
pF1KE0 DGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
::.:: ::. :. . ::.::..::::: :.::
XP_005 DGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
100 110 120 130
>>NP_001531 (OMIM: 602195,606595,608634) heat shock prot (205 aa)
initn: 444 init1: 349 opt: 384 Z-score: 491.9 bits: 97.7 E(85289): 1.2e-20
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (13-166:18-188)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
:: .. :::::: :: : . . : : :.::
NP_001 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
10 20 30 40 50 60
60 70 80 90 100
pF1KE0 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
:.. :: : ...:.::.: ::. :.:::.::.:.:: ::. :.:.
NP_001 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
70 80 90 100 110 120
110 120 130 140 150
pF1KE0 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
:::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... . : :
NP_001 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
130 140 150 160 170 180
160 170
pF1KE0 IPITREEKPAVTAAPKK
::.: : .
NP_001 IPVTFESRAQLGGPEAAKSDETAAK
190 200
>>NP_001532 (OMIM: 602179) heat shock protein beta-2 [Ho (182 aa)
initn: 358 init1: 310 opt: 381 Z-score: 488.9 bits: 97.0 E(85289): 1.7e-20
Smith-Waterman score: 381; 43.1% identity (72.3% similar) in 137 aa overlap (15-149:16-148)
10 20 30 40 50
pF1KE0 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPS
. : .:::: .: ::: :: ... : : .:.:: . ::.
NP_001 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEIL-TPTLYHGYYVRPRA---APA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 WFDT--GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISRE
. : ::.:: . .:.. :::.::.:.:. :... ...:: ..: .: :.:::.:::
NP_001 GEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSRE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 FHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
: : : .:::::: . ..:: ::.:....::
NP_001 FCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEE
120 130 140 150 160 170
NP_001 AAIVEP
180
175 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:20:11 2016 done: Thu Nov 3 08:20:12 2016
Total Scan time: 5.650 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]