FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0451, 308 aa 1>>>pF1KE0451 308 - 308 aa - 308 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0622+/-0.000762; mu= 16.6663+/- 0.046 mean_var=60.5378+/-12.118, 0's: 0 Z-trim(107.5): 14 B-trim: 0 in 0/50 Lambda= 0.164839 statistics sampled from 9608 (9613) to 9608 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.295), width: 16 Scan time: 2.580 The best scores are: opt bits E(32554) CCDS1227.1 TOMM40L gene_id:84134|Hs108|chr1 ( 308) 2082 503.4 9e-143 CCDS12646.1 TOMM40 gene_id:10452|Hs108|chr19 ( 361) 1319 322.0 4.3e-88 CCDS65700.1 TOMM40L gene_id:84134|Hs108|chr1 ( 274) 1238 302.6 2.2e-82 >>CCDS1227.1 TOMM40L gene_id:84134|Hs108|chr1 (308 aa) initn: 2082 init1: 2082 opt: 2082 Z-score: 2676.7 bits: 503.4 E(32554): 9e-143 Smith-Waterman score: 2082; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KE0 MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFH 250 260 270 280 290 300 pF1KE0 CGFSITVG :::::::: CCDS12 CGFSITVG >>CCDS12646.1 TOMM40 gene_id:10452|Hs108|chr19 (361 aa) initn: 1340 init1: 1319 opt: 1319 Z-score: 1695.0 bits: 322.0 E(32554): 4.3e-88 Smith-Waterman score: 1319; 64.6% identity (89.5% similar) in 285 aa overlap (24-308:77-361) 10 20 30 40 50 pF1KE0 MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVN :::::.:.: :: ::..:: :::::::.:: CCDS12 GTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVN 50 60 70 80 90 100 60 70 80 90 100 110 pF1KE0 KVLSSHFQVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLL : ::.:::: ::. .:..: .::. ..:.: ::::::.::..:::::.::::::::. CCDS12 KGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIH 110 120 130 140 150 160 120 130 140 150 160 170 pF1KE0 LLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLT :. ::.: ..::::.::..:: ::::::.:.::..::::::.. : :.:::.:::.: CCDS12 QLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSIT 170 180 190 200 210 220 180 190 200 210 220 230 pF1KE0 HRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGV :.:::::::::::::::....:::::. .:.::...:..: ::.:::.:..:.:::: CCDS12 PCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGV 230 240 250 260 270 280 240 250 260 270 280 290 pF1KE0 EFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLN ::::.::.:::. ::::.: ::.::..:.: ::::: :::.::::.::::.::::::::: CCDS12 EFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLN 290 300 310 320 330 340 300 pF1KE0 HWRNRFHCGFSITVG : .:.:.:::..:.: CCDS12 HRKNKFQCGFGLTIG 350 360 >>CCDS65700.1 TOMM40L gene_id:84134|Hs108|chr1 (274 aa) initn: 1238 init1: 1238 opt: 1238 Z-score: 1592.7 bits: 302.6 E(32554): 2.2e-82 Smith-Waterman score: 1797; 89.0% identity (89.0% similar) in 308 aa overlap (1-308:1-274) 10 20 30 40 50 60 pF1KE0 MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLR :::::::::::::::::::::::::::::::: CCDS65 QVAHTIHMSALGLPGYHLHAAYAGDWQLSPTE---------------------------- 70 80 90 130 140 150 160 170 180 pF1KE0 AKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 ------TQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGG 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 ELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 ELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTR 150 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 LQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFH 210 220 230 240 250 260 pF1KE0 CGFSITVG :::::::: CCDS65 CGFSITVG 270 308 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:57:52 2016 done: Thu Nov 3 07:57:53 2016 Total Scan time: 2.580 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]