FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0456, 274 aa 1>>>pF1KE0456 274 - 274 aa - 274 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.2600+/-0.000701; mu= 20.5149+/- 0.042 mean_var=60.9139+/-12.548, 0's: 0 Z-trim(109.3): 26 B-trim: 54 in 1/47 Lambda= 0.164330 statistics sampled from 10750 (10761) to 10750 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.331), width: 16 Scan time: 2.360 The best scores are: opt bits E(32554) CCDS10667.2 FAM57B gene_id:83723|Hs108|chr16 ( 274) 1903 459.3 1.4e-129 CCDS81967.1 FAM57B gene_id:83723|Hs108|chr16 ( 224) 1589 384.7 3.1e-107 CCDS10996.1 FAM57A gene_id:79850|Hs108|chr17 ( 257) 579 145.3 4.1e-35 CCDS82031.1 FAM57A gene_id:79850|Hs108|chr17 ( 225) 377 97.4 9.7e-21 >>CCDS10667.2 FAM57B gene_id:83723|Hs108|chr16 (274 aa) initn: 1903 init1: 1903 opt: 1903 Z-score: 2440.0 bits: 459.3 E(32554): 1.4e-129 Smith-Waterman score: 1903; 99.6% identity (99.6% similar) in 274 aa overlap (1-274:1-274) 10 20 30 40 50 60 pF1KE0 MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHRHKHQVKGHGGDDGAARAPGSTWA :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS10 TSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGDDGAARAPGSTWA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 IARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 YKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 YKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAAL 190 200 210 220 230 240 250 260 270 pF1KE0 LLAPQLYWFFLICRGACRLFWPRSRPPPACQAQD :::::::::::::::::::::::::::::::::: CCDS10 LLAPQLYWFFLICRGACRLFWPRSRPPPACQAQD 250 260 270 >>CCDS81967.1 FAM57B gene_id:83723|Hs108|chr16 (224 aa) initn: 1589 init1: 1589 opt: 1589 Z-score: 2038.8 bits: 384.7 E(32554): 3.1e-107 Smith-Waterman score: 1589; 99.6% identity (99.6% similar) in 224 aa overlap (51-274:1-224) 30 40 50 60 70 80 pF1KE0 NTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVSTSCKHIIDDQHWLSSAYTQF :::::::::::::::::::::::::::::: CCDS81 MASTAGYIVSTSCKHIIDDQHWLSSAYTQF 10 20 30 90 100 110 120 130 140 pF1KE0 AVPYFIYDIYAMFLCHRHKHQVKGHGGDDGAARAPGSTWAIARGYLHKEFLMVLHHAAMV :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: CCDS81 AVPYFIYDIYAMFLCHWHKHQVKGHGGDDGAARAPGSTWAIARGYLHKEFLMVLHHAAMV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 LVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSF 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 LCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAALLLAPQLYWFFLICRGACRLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAALLLAPQLYWFFLICRGACRLF 160 170 180 190 200 210 270 pF1KE0 WPRSRPPPACQAQD :::::::::::::: CCDS81 WPRSRPPPACQAQD 220 >>CCDS10996.1 FAM57A gene_id:79850|Hs108|chr17 (257 aa) initn: 817 init1: 573 opt: 579 Z-score: 743.9 bits: 145.3 E(32554): 4.1e-35 Smith-Waterman score: 852; 48.5% identity (72.1% similar) in 262 aa overlap (1-260:1-248) 10 20 30 40 50 60 pF1KE0 MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVS :: ...:.. ::::: : .:.: : : ..: :..:.::::::.:..:. .: .. CCDS10 MLLTLAGGALFFPGLFALCTWALRR-SQPGWSRTDCVMISTRLVSSVHAVLATGSGIVII 10 20 30 40 50 70 80 90 100 110 pF1KE0 TSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCH--RHKHQVKGHGGDDGAARAPGST :: .: .:::. :. : .::.::: :::.::. : . : :::. : CCDS10 RSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTRDQ----------NRAPSLT 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 WAIARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKIL :..: .. ::. :::....: :.. : ::::.::.. ::.::::: ::..: CCDS10 ---LRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCIFTAELSTPFVSLGRVL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 IQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGA :: :::::::.:::: : : .:: ::.::::..::.:::. :: :: ::..:: . :.. CCDS10 IQLKQQHTLLYKVNGILTLATFLSCRILLFPFMYWSYGRQQGLSLLQVPFSIPFYCNVAN 170 180 190 200 210 220 240 250 260 270 pF1KE0 ALLLAPQLYWFFLICRGACRLFWPRSRPPPACQAQD :.:.:::.::: :.:: : ::: CCDS10 AFLVAPQIYWFCLLCRKAVRLFDTPQAKKDG 230 240 250 >>CCDS82031.1 FAM57A gene_id:79850|Hs108|chr17 (225 aa) initn: 621 init1: 377 opt: 377 Z-score: 485.8 bits: 97.4 E(32554): 9.7e-21 Smith-Waterman score: 655; 41.6% identity (63.0% similar) in 262 aa overlap (1-260:1-216) 10 20 30 40 50 60 pF1KE0 MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVS :: ...:.. ::::: : .:.: : : ..: :..:.::::::.:..:. .: .. CCDS82 MLLTLAGGALFFPGLFALCTWALRR-SQPGWSRTDCVMISTRLVSSVHAVLATGSGIVII 10 20 30 40 50 70 80 90 100 110 pF1KE0 TSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCH--RHKHQVKGHGGDDGAARAPGST :: .: .:::. :. : .::.::: :::.::. : . : :::. : CCDS82 RSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTRDQ----------NRAPSLT 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 WAIARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKIL :..: .. ::. :::....: :.. CCDS82 ---LRNFLSRNRLMITHHAVILFVLVPVA------------------------------- 110 120 130 180 190 200 210 220 230 pF1KE0 IQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGA : :::::::.:::: : : .:: ::.::::..::.:::. :: :: ::..:: . :.. CCDS82 -QLKQQHTLLYKVNGILTLATFLSCRILLFPFMYWSYGRQQGLSLLQVPFSIPFYCNVAN 140 150 160 170 180 190 240 250 260 270 pF1KE0 ALLLAPQLYWFFLICRGACRLFWPRSRPPPACQAQD :.:.:::.::: :.:: : ::: CCDS82 AFLVAPQIYWFCLLCRKAVRLFDTPQAKKDG 200 210 220 274 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:39:49 2016 done: Thu Nov 3 07:39:50 2016 Total Scan time: 2.360 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]