FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0471, 439 aa 1>>>pF1KE0471 439 - 439 aa - 439 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1848+/-0.000858; mu= 5.5623+/- 0.051 mean_var=174.0194+/-35.212, 0's: 0 Z-trim(112.8): 20 B-trim: 8 in 1/50 Lambda= 0.097224 statistics sampled from 13496 (13512) to 13496 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.415), width: 16 Scan time: 3.450 The best scores are: opt bits E(32554) CCDS33059.1 PNMAL1 gene_id:55228|Hs108|chr19 ( 439) 2946 425.1 6.7e-119 CCDS46124.1 PNMAL1 gene_id:55228|Hs108|chr19 ( 378) 2464 357.5 1.3e-98 CCDS9818.1 PNMA1 gene_id:9240|Hs108|chr14 ( 353) 508 83.1 4.9e-16 CCDS9908.1 MOAP1 gene_id:64112|Hs108|chr14 ( 351) 478 78.9 9.1e-15 CCDS34868.1 PNMA2 gene_id:10687|Hs108|chr8 ( 364) 460 76.4 5.4e-14 CCDS65344.1 PNMA3 gene_id:29944|Hs108|chrX ( 455) 441 73.8 4.1e-13 CCDS35435.2 PNMA3 gene_id:29944|Hs108|chrX ( 463) 441 73.8 4.1e-13 CCDS14718.1 PNMA5 gene_id:114824|Hs108|chrX ( 448) 432 72.5 9.6e-13 >>CCDS33059.1 PNMAL1 gene_id:55228|Hs108|chr19 (439 aa) initn: 2946 init1: 2946 opt: 2946 Z-score: 2248.1 bits: 425.1 E(32554): 6.7e-119 Smith-Waterman score: 2946; 99.8% identity (100.0% similar) in 439 aa overlap (1-439:1-439) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: CCDS33 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 MRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRG 370 380 390 400 410 420 430 pF1KE0 PKAKPEGSPRRATNESRKV ::::::::::::::::::: CCDS33 PKAKPEGSPRRATNESRKV 430 >>CCDS46124.1 PNMAL1 gene_id:55228|Hs108|chr19 (378 aa) initn: 2464 init1: 2464 opt: 2464 Z-score: 1883.7 bits: 357.5 E(32554): 1.3e-98 Smith-Waterman score: 2464; 99.7% identity (100.0% similar) in 366 aa overlap (1-366:1-366) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: CCDS46 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 MRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRG :::::: CCDS46 MRKKKKNPERFDLGDHPY 370 >>CCDS9818.1 PNMA1 gene_id:9240|Hs108|chr14 (353 aa) initn: 490 init1: 307 opt: 508 Z-score: 401.3 bits: 83.1 E(32554): 4.9e-16 Smith-Waterman score: 508; 52.3% identity (78.1% similar) in 155 aa overlap (5-159:1-150) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF :::.:::::::::.:. .:.::: ::: .: .:::::::.... : :: :...: CCDS98 MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAM-PQVSYRMLGRMF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT ::::.::::.:. .:. ..::::.::.::::.:. . ::.:::::. :. :: :: : CCDS98 WREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA .::.:.: ...:: . . :: :: :. .: :.: CCDS98 VQDVARVLGFQNPTPTPG----PEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR CCDS98 PGEETFDPWLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLK 180 190 200 210 220 230 >>CCDS9908.1 MOAP1 gene_id:64112|Hs108|chr14 (351 aa) initn: 475 init1: 475 opt: 478 Z-score: 378.6 bits: 78.9 E(32554): 9.1e-15 Smith-Waterman score: 478; 38.7% identity (69.1% similar) in 194 aa overlap (5-197:1-193) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF :.. :::::::::... ...::..:: ..:. :::::.:.. :.::: :: :...: CCDS99 MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT :.:: :.::. . .. . .:.:.::.::.:::. . : : ::. ::::: .:: : CCDS99 RRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMT 60 70 80 90 100 110 130 140 150 160 170 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMD-AEIRSREEARAQEA .. : : .. .:. .: . :: :: :. : :. . :. ..: .. : CCDS99 VGELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 AEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKS .: ::.. : . . . .: CCDS99 GE-EEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQ 180 190 200 210 220 230 >>CCDS34868.1 PNMA2 gene_id:10687|Hs108|chr8 (364 aa) initn: 460 init1: 460 opt: 460 Z-score: 364.8 bits: 76.4 E(32554): 5.4e-14 Smith-Waterman score: 460; 41.3% identity (64.7% similar) in 201 aa overlap (5-205:1-201) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF ::. ::::::: : :: ..::.::::: : .:::.:.:. .:. :: :: :.::: CCDS34 MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT ..::..:.:.:. : ...:.:: : :.::::.:. . :.::.:::. :: ::. ::.: CCDS34 RKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA . : : . . . :: :. :: .. . : .. : . . : : CCDS34 VSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR : : . .: : . ::. : :: CCDS34 EEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEA 180 190 200 210 220 230 >>CCDS65344.1 PNMA3 gene_id:29944|Hs108|chrX (455 aa) initn: 450 init1: 419 opt: 441 Z-score: 349.0 bits: 73.8 E(32554): 4.1e-13 Smith-Waterman score: 448; 34.2% identity (63.5% similar) in 222 aa overlap (5-212:1-222) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF : ..::.::::: ... .: .:. :::::::. :.::::. . :: ::.....: CCDS65 MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEETLQEACRHLGRYRVIGRMF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT ::::..: :.:... .. . .:::.::.:: :.:. . ..:.:::. ::.::. : :: CCDS65 RREENAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRT 60 70 80 90 100 110 130 140 150 160 170 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPE--NWAEALGVLLGAVVQIIFCMDAEIRSREEARAQE :. :.: . . :: .::..::. . ... .. . .. : . CCDS65 VSDMNRVLGSDTNCSAPRVTISPEFWTWAQTLGAAVQPLLEQMLYRELRVFSGNTISIPG 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 AAEF--------EEMAAWALAAGRKVKKEP----GLAAEVGSALKAETPNNWNATEDQHE : : : . : . :.: .. : : .: :.:.: CCDS65 ALAFDAWLEHTTEMLQMWQVPEGEKRRRLMECLRGPALQVVSGLRASNASITVEECLAAL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 PTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISE CCDS65 QQVFGPVESHKIAQVKLCKAYQEAGEKVSSFVLRLEPLLQRAVENNVVSRRNVNQTRLKR 240 250 260 270 280 290 >>CCDS35435.2 PNMA3 gene_id:29944|Hs108|chrX (463 aa) initn: 450 init1: 419 opt: 441 Z-score: 348.9 bits: 73.8 E(32554): 4.1e-13 Smith-Waterman score: 448; 34.2% identity (63.5% similar) in 222 aa overlap (5-212:1-222) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF : ..::.::::: ... .: .:. :::::::. :.::::. . :: ::.....: CCDS35 MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEETLQEACRHLGRYRVIGRMF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT ::::..: :.:... .. . .:::.::.:: :.:. . ..:.:::. ::.::. : :: CCDS35 RREENAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRT 60 70 80 90 100 110 130 140 150 160 170 pF1KE0 WEDVVRLLQLNHPTLSQNQHQPPE--NWAEALGVLLGAVVQIIFCMDAEIRSREEARAQE :. :.: . . :: .::..::. . ... .. . .. : . CCDS35 VSDMNRVLGSDTNCSAPRVTISPEFWTWAQTLGAAVQPLLEQMLYRELRVFSGNTISIPG 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 AAEF--------EEMAAWALAAGRKVKKEP----GLAAEVGSALKAETPNNWNATEDQHE : : : . : . :.: .. : : .: :.:.: CCDS35 ALAFDAWLEHTTEMLQMWQVPEGEKRRRLMECLRGPALQVVSGLRASNASITVEECLAAL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 PTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISE CCDS35 QQVFGPVESHKIAQVKLCKAYQEAGEKVSSFVLRLEPLLQRAVENNVVSRRNVNQTRLKR 240 250 260 270 280 290 >>CCDS14718.1 PNMA5 gene_id:114824|Hs108|chrX (448 aa) initn: 459 init1: 432 opt: 432 Z-score: 342.2 bits: 72.5 E(32554): 9.6e-13 Smith-Waterman score: 435; 41.5% identity (73.2% similar) in 164 aa overlap (5-155:1-164) 10 20 30 40 50 60 pF1KE0 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRALNKIF ::..::::::.::..: ...::..::: .:...::..:... :.:: ::.:...: CCDS14 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT ::.:.::..::... :: .:.: ..::.:: :.:: . . : :::. :: :: :::. CCDS14 RREDNAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRS 60 70 80 90 100 110 130 140 150 160 pF1KE0 WEDVVRLL--------QLNHPTLSQNQH---QPPEN--WAEALGVLLGAVVQIIFCMDAE ::.: : .:. .. : . .::.. : . : :. : CCDS14 MTDVARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 IRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEP CCDS14 DWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFG 180 190 200 210 220 230 439 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:09:15 2016 done: Thu Nov 3 06:09:16 2016 Total Scan time: 3.450 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]