FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0474, 167 aa 1>>>pF1KE0474 167 - 167 aa - 167 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9749+/-0.000625; mu= 13.9505+/- 0.037 mean_var=69.6781+/-14.150, 0's: 0 Z-trim(111.8): 83 B-trim: 133 in 2/47 Lambda= 0.153648 statistics sampled from 12536 (12644) to 12536 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.388), width: 16 Scan time: 1.730 The best scores are: opt bits E(32554) CCDS348.1 PTP4A2 gene_id:8073|Hs108|chr1 ( 167) 1162 265.8 8.8e-72 CCDS4965.1 PTP4A1 gene_id:7803|Hs108|chr6 ( 173) 1044 239.7 6.7e-64 CCDS6383.1 PTP4A3 gene_id:11156|Hs108|chr8 ( 173) 927 213.7 4.3e-56 CCDS59193.1 PTP4A2 gene_id:8073|Hs108|chr1 ( 142) 752 174.9 1.8e-44 CCDS53292.1 PTP4A2 gene_id:8073|Hs108|chr1 ( 136) 751 174.6 2e-44 CCDS6382.1 PTP4A3 gene_id:11156|Hs108|chr8 ( 148) 602 141.6 1.9e-34 >>CCDS348.1 PTP4A2 gene_id:8073|Hs108|chr1 (167 aa) initn: 1162 init1: 1162 opt: 1162 Z-score: 1402.2 bits: 265.8 E(32554): 8.8e-72 Smith-Waterman score: 1162; 100.0% identity (100.0% similar) in 167 aa overlap (1-167:1-167) 10 20 30 40 50 60 pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 70 80 90 100 110 120 130 140 150 160 pF1KE0 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ ::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ 130 140 150 160 >>CCDS4965.1 PTP4A1 gene_id:7803|Hs108|chr6 (173 aa) initn: 1046 init1: 1023 opt: 1044 Z-score: 1260.6 bits: 239.7 E(32554): 6.7e-64 Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (1-167:4-173) 10 20 30 40 50 pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK ::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . ::: CCDS49 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI :::::::::::::::: ::::::::.:.: :::::::::.:::::::::::::::::::: CCDS49 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ : ::::::::::::::::::::::::::::::::::::::.:.::: ::.: CCDS49 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 130 140 150 160 170 >>CCDS6383.1 PTP4A3 gene_id:11156|Hs108|chr8 (173 aa) initn: 929 init1: 912 opt: 927 Z-score: 1120.5 bits: 213.7 E(32554): 4.3e-56 Smith-Waterman score: 927; 77.5% identity (92.3% similar) in 169 aa overlap (1-166:4-172) 10 20 30 40 50 pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK ::::::::.::..::::::::::::::. : :.:::::.::.::::..::::.:.:: CCDS63 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI .:: :.:::::::::::...:.:::.:.:.:: : :: :::::::::::::::::::::: CCDS63 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ : :::::::.::::::::::.::::: ::::::::.::::.: . : ::: CCDS63 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 130 140 150 160 170 >>CCDS59193.1 PTP4A2 gene_id:8073|Hs108|chr1 (142 aa) initn: 752 init1: 752 opt: 752 Z-score: 912.0 bits: 174.9 E(32554): 1.8e-44 Smith-Waterman score: 941; 85.0% identity (85.0% similar) in 167 aa overlap (1-167:1-142) 10 20 30 40 50 60 pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG ::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGR------------- 70 80 90 100 130 140 150 160 pF1KE0 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ ::::::::::::::::::::::::::::::::::: CCDS59 ------------KRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ 110 120 130 140 >>CCDS53292.1 PTP4A2 gene_id:8073|Hs108|chr1 (136 aa) initn: 950 init1: 751 opt: 751 Z-score: 911.1 bits: 174.6 E(32554): 2e-44 Smith-Waterman score: 890; 81.4% identity (81.4% similar) in 167 aa overlap (1-167:1-136) 10 20 30 40 50 60 pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI :::::::::::::::::::::::::::::::: CCDS53 MNRPAPVEISYENMRFLITHNPTNATLNKFTE---------------------------- 10 20 30 70 80 90 100 110 120 pF1KE0 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ---DWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 40 50 60 70 80 130 140 150 160 pF1KE0 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ ::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ 90 100 110 120 130 >>CCDS6382.1 PTP4A3 gene_id:11156|Hs108|chr8 (148 aa) initn: 769 init1: 602 opt: 602 Z-score: 732.1 bits: 141.6 E(32554): 1.9e-34 Smith-Waterman score: 721; 63.9% identity (78.1% similar) in 169 aa overlap (1-166:4-147) 10 20 30 40 50 pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK ::::::::.::..::::::::::::::. : :.:::::.::.::::..::::.:.:: CCDS63 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI .:: :.:::::::::::...:.:::.:.:.:: : :: :::::::::::: CCDS63 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGR---------- 70 80 90 100 110 120 130 140 150 160 pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ :::::.::::: ::::::::.::::.: . : ::: CCDS63 ---------------KRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 120 130 140 167 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:56:04 2016 done: Thu Nov 3 05:56:04 2016 Total Scan time: 1.730 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]