FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0476, 245 aa 1>>>pF1KE0476 245 - 245 aa - 245 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5103+/-0.000404; mu= 3.4609+/- 0.025 mean_var=325.1685+/-67.308, 0's: 0 Z-trim(122.1): 421 B-trim: 649 in 1/57 Lambda= 0.071125 statistics sampled from 39324 (39786) to 39324 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.466), width: 16 Scan time: 6.980 The best scores are: opt bits E(85289) NP_001107573 (OMIM: 120575,613652) complement C1q ( 245) 1737 190.9 1.8e-48 NP_758957 (OMIM: 120575,613652) complement C1q sub ( 245) 1737 190.9 1.8e-48 XP_011540361 (OMIM: 120570,613652) PREDICTED: comp ( 253) 816 96.4 5.1e-20 NP_000482 (OMIM: 120570,613652) complement C1q sub ( 253) 816 96.4 5.1e-20 NP_057075 (OMIM: 120550,613652) complement C1q sub ( 245) 539 68.0 1.8e-11 NP_056460 (OMIM: 605670,608752) complement C1q tum ( 243) 524 66.4 5.2e-11 NP_001265360 (OMIM: 605670,608752) complement C1q ( 243) 524 66.4 5.2e-11 NP_001008224 (OMIM: 615229) complement C1q-like pr ( 238) 439 57.7 2.2e-08 XP_011536572 (OMIM: 615229) PREDICTED: complement ( 227) 393 52.9 5.5e-07 NP_852100 (OMIM: 612045) complement C1q tumor necr ( 319) 349 48.6 1.6e-05 NP_112207 (OMIM: 612045) complement C1q tumor necr ( 246) 346 48.2 1.6e-05 XP_011533735 (OMIM: 120110,156500) PREDICTED: coll ( 680) 351 49.2 2.1e-05 XP_016865738 (OMIM: 120110,156500) PREDICTED: coll ( 680) 351 49.2 2.1e-05 XP_011533734 (OMIM: 120110,156500) PREDICTED: coll ( 680) 351 49.2 2.1e-05 NP_000484 (OMIM: 120110,156500) collagen alpha-1(X ( 680) 351 49.2 2.1e-05 XP_006715396 (OMIM: 120110,156500) PREDICTED: coll ( 680) 351 49.2 2.1e-05 XP_016865737 (OMIM: 120110,156500) PREDICTED: coll ( 680) 351 49.2 2.1e-05 XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289) 338 48.3 7.9e-05 XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330) 338 48.3 8.1e-05 XP_016883155 (OMIM: 120270,600969,603932) PREDICTE ( 486) 329 46.8 8.3e-05 XP_011526847 (OMIM: 120270,600969,603932) PREDICTE ( 552) 329 46.9 9e-05 NP_000486 (OMIM: 301050,303630) collagen alpha-5(I (1685) 338 48.4 9.3e-05 XP_016884749 (OMIM: 301050,303630) PREDICTED: coll (1690) 338 48.4 9.3e-05 NP_203699 (OMIM: 301050,303630) collagen alpha-5(I (1691) 338 48.4 9.3e-05 XP_016884748 (OMIM: 301050,303630) PREDICTED: coll (1693) 338 48.4 9.3e-05 NP_065084 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 331 47.2 9.3e-05 NP_001841 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 331 47.2 9.3e-05 XP_011529151 (OMIM: 301050,303630) PREDICTED: coll (1696) 338 48.4 9.3e-05 XP_016868640 (OMIM: 610026) PREDICTED: collagen al (1552) 337 48.3 9.5e-05 NP_001844 (OMIM: 120270,600969,603932) collagen al ( 684) 329 47.0 0.0001 XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 333 47.7 0.00011 XP_016884752 (OMIM: 301050,303630) PREDICTED: coll (1136) 332 47.6 0.00011 XP_006717371 (OMIM: 608461,615155) PREDICTED: coll (1842) 336 48.3 0.00011 XP_011508874 (OMIM: 120131,203780) PREDICTED: coll (1132) 328 47.2 0.00015 XP_011508871 (OMIM: 120131,203780) PREDICTED: coll (1414) 328 47.3 0.00017 XP_016858789 (OMIM: 120131,203780) PREDICTED: coll (1414) 328 47.3 0.00017 XP_011508872 (OMIM: 120131,203780) PREDICTED: coll (1414) 328 47.3 0.00017 XP_011508870 (OMIM: 120131,203780) PREDICTED: coll (1419) 328 47.3 0.00017 XP_011508869 (OMIM: 120131,203780) PREDICTED: coll (1420) 328 47.3 0.00017 XP_011508868 (OMIM: 120131,203780) PREDICTED: coll (1420) 328 47.3 0.00017 XP_011508867 (OMIM: 120131,203780) PREDICTED: coll (1424) 328 47.3 0.00017 NP_000485 (OMIM: 113811,122400,226650) collagen al (1497) 328 47.3 0.00018 XP_005246339 (OMIM: 120131,203780) PREDICTED: coll (1505) 328 47.3 0.00018 XP_011515191 (OMIM: 610026) PREDICTED: collagen al (1058) 325 46.8 0.00018 XP_016858788 (OMIM: 120131,203780) PREDICTED: coll (1518) 328 47.3 0.00018 XP_016858787 (OMIM: 120131,203780) PREDICTED: coll (1608) 328 47.4 0.00018 XP_011508864 (OMIM: 120131,203780) PREDICTED: coll (1608) 328 47.4 0.00018 XP_011508863 (OMIM: 120131,203780) PREDICTED: coll (1608) 328 47.4 0.00018 XP_011508862 (OMIM: 120131,203780) PREDICTED: coll (1612) 328 47.4 0.00018 XP_011508861 (OMIM: 120131,203780) PREDICTED: coll (1612) 328 47.4 0.00018 >>NP_001107573 (OMIM: 120575,613652) complement C1q subc (245 aa) initn: 1737 init1: 1737 opt: 1737 Z-score: 991.3 bits: 190.9 E(85289): 1.8e-48 Smith-Waterman score: 1737; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF 190 200 210 220 230 240 pF1KE0 LLFPD ::::: NP_001 LLFPD >>NP_758957 (OMIM: 120575,613652) complement C1q subcomp (245 aa) initn: 1737 init1: 1737 opt: 1737 Z-score: 991.3 bits: 190.9 E(85289): 1.8e-48 Smith-Waterman score: 1737; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF 190 200 210 220 230 240 pF1KE0 LLFPD ::::: NP_758 LLFPD >>XP_011540361 (OMIM: 120570,613652) PREDICTED: compleme (253 aa) initn: 593 init1: 593 opt: 816 Z-score: 480.4 bits: 96.4 E(85289): 5.1e-20 Smith-Waterman score: 816; 50.0% identity (74.0% similar) in 246 aa overlap (8-245:5-250) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLR--GQANTGCYG---IPGMPGLPGAPGKDGYDGLPG .: .. .:.::::: : .::. .: : :::.::.::.:: :: : :: XP_011 MMMKIPWGSIPVLMLLLLLGLIDISQAQLSCTGPPAIPGIPGIPGTPGPDGQPGTPG 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK ::: :.:.. : .: :.::.::.::.::: :: :: : : :: : :: :: : :: XP_011 IKGEKGLPGLAGDHGEFGEKGDPGIPGNPGKVGPKGPMGPKGGPGAPGAPGPKGESGDYK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 QKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHT . .:..:: . : .. :::. :.:: ...:. .:::::::::::::.:::: XP_011 ATQKIAFSATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFTCKVPGLYYFTYHASSR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 ANLCVLLYRS---GVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQG .:::: :.:. . :::::: .. .: ::..::..:.:. ::.:.: ..: ...:..: XP_011 GNLCVNLMRGRERAQKVVTFCDYAYNTFQVTTGGMVLKLEQGENVFLQATDKNSLLGMEG 180 190 200 210 220 230 240 pF1KE0 SDSVFSGFLLFPD ..:.::::::::: XP_011 ANSIFSGFLLFPDMEA 240 250 >>NP_000482 (OMIM: 120570,613652) complement C1q subcomp (253 aa) initn: 593 init1: 593 opt: 816 Z-score: 480.4 bits: 96.4 E(85289): 5.1e-20 Smith-Waterman score: 816; 50.0% identity (74.0% similar) in 246 aa overlap (8-245:5-250) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLR--GQANTGCYG---IPGMPGLPGAPGKDGYDGLPG .: .. .:.::::: : .::. .: : :::.::.::.:: :: : :: NP_000 MMMKIPWGSIPVLMLLLLLGLIDISQAQLSCTGPPAIPGIPGIPGTPGPDGQPGTPG 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK ::: :.:.. : .: :.::.::.::.::: :: :: : : :: : :: :: : :: NP_000 IKGEKGLPGLAGDHGEFGEKGDPGIPGNPGKVGPKGPMGPKGGPGAPGAPGPKGESGDYK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 QKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHT . .:..:: . : .. :::. :.:: ...:. .:::::::::::::.:::: NP_000 ATQKIAFSATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFTCKVPGLYYFTYHASSR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 ANLCVLLYRS---GVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQG .:::: :.:. . :::::: .. .: ::..::..:.:. ::.:.: ..: ...:..: NP_000 GNLCVNLMRGRERAQKVVTFCDYAYNTFQVTTGGMVLKLEQGENVFLQATDKNSLLGMEG 180 190 200 210 220 230 240 pF1KE0 SDSVFSGFLLFPD ..:.::::::::: NP_000 ANSIFSGFLLFPDMEA 240 250 >>NP_057075 (OMIM: 120550,613652) complement C1q subcomp (245 aa) initn: 464 init1: 169 opt: 539 Z-score: 327.0 bits: 68.0 E(85289): 1.8e-11 Smith-Waterman score: 539; 38.8% identity (63.2% similar) in 242 aa overlap (15-244:8-243) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTG-CYGIPGMPGLPGAPGKDGYDGLPGPKGE :.: .: . : .... : . : : : ::. : :: : .:: NP_057 MEGPRGWLVLCVLAISLASMVTEDLCRAPDGKKGEAGRPGRRGRPGLKGEQGE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 PGIPAI-PGIRGPKGQKGEPGLPGHPGK---NGPMGPPGMPGVPGPMGIPGEPGEEGRYK :: :.: ::.: ::..:::: :.::: :: :: : :.:: : : ::. : NP_057 PGAPGIRTGIQGLKGDQGEPGPSGNPGKVGYPGPSGPLGARGIPGIKGTKGSPGN---IK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 QKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHT .. . .:.. :. .:: .... :..:.:: . :.. .:.:.: ::: :::.... NP_057 DQPRPAFSAIRR--NPPMGGNVVIFDTVITNQEEPYQNHSGRFVCTVPGYYYFTFQVLSQ 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 ANLCVLLYRSGV----KVVTFCGHTSK-TNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGI ..:. . :. . . :: :.: :: :::..:.:: :..::. . . NP_057 WEICLSIVSSSRGQVRRSLGFCDTTNKGLFQVVSGGMVLQLQQGDQVWVEKDPKKGHI-Y 170 180 190 200 210 220 240 pF1KE0 QGS--DSVFSGFLLFPD ::: ::::::::.:: NP_057 QGSEADSVFSGFLIFPSA 230 240 >>NP_056460 (OMIM: 605670,608752) complement C1q tumor n (243 aa) initn: 627 init1: 256 opt: 524 Z-score: 318.7 bits: 66.4 E(85289): 5.2e-11 Smith-Waterman score: 533; 41.1% identity (62.6% similar) in 246 aa overlap (13-245:1-235) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLR-GQANTGCYGIP----GMPGLPGAPGKDGYDGLPG .. ::.:::: : :. :: : :::::.::. : .:::: NP_056 MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSQGLPG 10 20 30 40 60 70 80 90 100 110 pF1KE0 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK :. : . :: : ::. :.::::: : : :: : :: : : :: . NP_056 RDGRDGRDGAPGAPGEKGEGGRPGLPG------PRGDPGPRGEAGPAGPTGPAGECSVPP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 QKFQSVFTVTR-QTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS- . :.:.. : ... :: .. . :. ::.: :: ::. ::::::.:::.:::. ::. NP_056 R---SAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATV 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 HTANLCVLLYRSGVKVVTFC---GHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGI . :.: : ..: ....: : : .. :::...::. ..::. :. :..:: NP_056 YRASLQFDLVKNGESIASFFQFFGGWPKPASL-SGGAMVRLEPEDQVWVQVG-VGDYIGI 160 170 180 190 200 210 240 pF1KE0 QGS---DSVFSGFLLFPD .: ::.:::::.. : NP_056 YASIKTDSTFSGFLVYSDWHSSPVFA 220 230 240 >>NP_001265360 (OMIM: 605670,608752) complement C1q tumo (243 aa) initn: 627 init1: 256 opt: 524 Z-score: 318.7 bits: 66.4 E(85289): 5.2e-11 Smith-Waterman score: 533; 41.1% identity (62.6% similar) in 246 aa overlap (13-245:1-235) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLR-GQANTGCYGIP----GMPGLPGAPGKDGYDGLPG .. ::.:::: : :. :: : :::::.::. : .:::: NP_001 MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSQGLPG 10 20 30 40 60 70 80 90 100 110 pF1KE0 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK :. : . :: : ::. :.::::: : : :: : :: : : :: . NP_001 RDGRDGRDGAPGAPGEKGEGGRPGLPG------PRGDPGPRGEAGPAGPTGPAGECSVPP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 QKFQSVFTVTR-QTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS- . :.:.. : ... :: .. . :. ::.: :: ::. ::::::.:::.:::. ::. NP_001 R---SAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATV 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 HTANLCVLLYRSGVKVVTFC---GHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGI . :.: : ..: ....: : : .. :::...::. ..::. :. :..:: NP_001 YRASLQFDLVKNGESIASFFQFFGGWPKPASL-SGGAMVRLEPEDQVWVQVG-VGDYIGI 160 170 180 190 200 210 240 pF1KE0 QGS---DSVFSGFLLFPD .: ::.:::::.. : NP_001 YASIKTDSTFSGFLVYSDWHSSPVFA 220 230 240 >>NP_001008224 (OMIM: 615229) complement C1q-like protei (238 aa) initn: 295 init1: 295 opt: 439 Z-score: 271.7 bits: 57.7 E(85289): 2.2e-08 Smith-Waterman score: 439; 34.3% identity (60.7% similar) in 242 aa overlap (15-245:2-238) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPL-----RGQANTGCYGIPGMPGLPGAPGKDGYDGLPG .::::. .:: :: :. : : : .: : :: . NP_001 MVLLLLVAIPLLVHSSRGPAHYEMLGRCRMVCDPHGPRGPGPDG--A 10 20 30 40 60 70 80 90 100 110 pF1KE0 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK : . : .: :: .: :..:. :: : :: :: :::: :: ::: : :: :: : NP_001 PASVPPFP--PGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPG-PGPGGVAP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 QK-FQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHA-- . .. ..: ..::. :.:: . :....::::: .::.:.:.::. NP_001 AAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLM 110 120 130 140 150 160 180 190 200 210 220 pF1KE0 --SHTANLCVLLYRSG-VKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVG . ... . :...: :.. .. .... . :..:.:.:.::.::.. .. : NP_001 RGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGG 170 180 190 200 210 220 230 240 pF1KE0 IQGSDSVFSGFLLFPD .. :.::::...:: NP_001 NTNKYSTFSGFIIYPD 230 >>XP_011536572 (OMIM: 615229) PREDICTED: complement C1q- (227 aa) initn: 295 init1: 295 opt: 393 Z-score: 246.4 bits: 52.9 E(85289): 5.5e-07 Smith-Waterman score: 393; 34.2% identity (60.7% similar) in 219 aa overlap (15-222:2-215) 10 20 30 40 50 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPL-----RGQANTGCYGIPGMPGLPGAPGKDGYDGLPG .::::. .:: :: :. : : : .: : :: . XP_011 MVLLLLVAIPLLVHSSRGPAHYEMLGRCRMVCDPHGPRGPGPDG--A 10 20 30 40 60 70 80 90 100 110 pF1KE0 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK : . : .: :: .: :..:. :: : :: :: :::: :: ::: : :: :: : XP_011 PASVPPFP--PGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPG-PGPGGVAP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 QK-FQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHA-- . .. ..: ..::. :.:: . :....::::: .::.:.:.::. XP_011 AAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLM 110 120 130 140 150 160 180 190 200 210 220 pF1KE0 --SHTANLCVLLYRSG-VKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVG . ... . :...: :.. .. .... . :..:.:.:.::.::.. .. XP_011 RGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGG 170 180 190 200 210 220 230 240 pF1KE0 IQGSDSVFSGFLLFPD XP_011 NTNKV >>NP_852100 (OMIM: 612045) complement C1q tumor necrosis (319 aa) initn: 425 init1: 198 opt: 349 Z-score: 220.4 bits: 48.6 E(85289): 1.6e-05 Smith-Waterman score: 349; 33.5% identity (56.5% similar) in 248 aa overlap (5-243:81-316) 10 20 30 pF1KE0 MDVGPSSLPHLGLKLLLLLLLLPLRGQA-NTGCY :. ::: .. : . . ::. .:: NP_852 GSRREKVRERSHPKTGTVDNNTSTDLKSLRPDELPHP--EVDDLAQITTFWGQSPQTG-- 60 70 80 90 100 40 50 60 70 80 pF1KE0 GIPGMPGLPGAPGKD----GYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP :.: : : ::.: ::: : ::::. : : .: :. : :. : .: NP_852 GLP--PDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGD 110 120 130 140 150 160 90 100 110 120 130 140 pF1KE0 MGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQG .:: : : :: : : :: ..: .: .. :: :: : :..: :: . NP_852 LGPRGERGQHGPKGEKGYPG----IPPELQIAFMASLATHFS-NQNSGIIFSSVETNIGN 170 180 190 200 210 150 160 170 180 190 200 pF1KE0 DYDTSTGKFTCKVPGLYYFVYHA-SH--TANLCVLLYRSGVKVVTFCGHTSK-TNQVNSG .:. ::.: : :.:.:.. .: . .. : :...: : .. .. : ....:. NP_852 FFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSN 220 230 240 250 260 270 210 220 230 240 pF1KE0 GVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLFPD ..:.: :.:::: ... . : . :.:.::::: NP_852 HAVLKLAKGDEVWLRMGNGA-LHGDHQRFSTFAGFLLFETK 280 290 300 310 245 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:34:17 2016 done: Thu Nov 3 05:34:18 2016 Total Scan time: 6.980 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]