FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0481, 419 aa 1>>>pF1KE0481 419 - 419 aa - 419 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8955+/-0.000464; mu= 9.5573+/- 0.029 mean_var=165.9794+/-36.055, 0's: 0 Z-trim(113.7): 302 B-trim: 541 in 1/58 Lambda= 0.099551 statistics sampled from 22709 (23130) to 22709 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.271), width: 16 Scan time: 8.890 The best scores are: opt bits E(85289) NP_001171754 (OMIM: 176390) pregnancy-specific bet ( 419) 2827 418.8 1.3e-116 NP_008836 (OMIM: 176390) pregnancy-specific beta-1 ( 426) 2791 413.6 4.6e-115 NP_001171755 (OMIM: 176390) pregnancy-specific bet ( 417) 2786 412.9 7.5e-115 NP_001284702 (OMIM: 176390) pregnancy-specific bet ( 428) 2786 412.9 7.6e-115 NP_001123639 (OMIM: 176397) pregnancy-specific bet ( 419) 2624 389.6 7.6e-108 NP_874366 (OMIM: 176397) pregnancy-specific beta-1 ( 426) 2594 385.3 1.5e-106 NP_002774 (OMIM: 176396) putative pregnancy-specif ( 419) 2546 378.4 1.8e-104 NP_066296 (OMIM: 176392) pregnancy-specific beta-1 ( 428) 2546 378.5 1.8e-104 NP_002771 (OMIM: 176393) pregnancy-specific beta-1 ( 419) 2489 370.3 5.2e-102 XP_016882486 (OMIM: 176393) PREDICTED: pregnancy-s ( 426) 2463 366.5 7e-101 NP_002773 (OMIM: 176395) pregnancy-specific beta-1 ( 435) 2435 362.5 1.2e-99 NP_001027020 (OMIM: 176395) pregnancy-specific bet ( 424) 2428 361.5 2.3e-99 XP_016882485 (OMIM: 176393) PREDICTED: pregnancy-s ( 435) 2359 351.6 2.2e-96 XP_016882496 (OMIM: 176398) PREDICTED: pregnancy-s ( 436) 2357 351.3 2.7e-96 XP_016882493 (OMIM: 176398) PREDICTED: pregnancy-s ( 495) 2357 351.4 3e-96 NP_002775 (OMIM: 176398) pregnancy-specific beta-1 ( 426) 2350 350.3 5.4e-96 XP_016882484 (OMIM: 176393) PREDICTED: pregnancy-s ( 442) 2333 347.9 3e-95 NP_001123640 (OMIM: 176397) pregnancy-specific bet ( 297) 1772 267.1 4.1e-71 XP_011525289 (OMIM: 176397) PREDICTED: pregnancy-s ( 306) 1772 267.1 4.2e-71 NP_001193579 (OMIM: 176396) putative pregnancy-spe ( 297) 1711 258.4 1.8e-68 XP_011525290 (OMIM: 176397) PREDICTED: pregnancy-s ( 258) 1671 252.6 8.7e-67 NP_001303268 (OMIM: 176393) pregnancy-specific bet ( 297) 1670 252.5 1.1e-66 XP_011525427 (OMIM: 176390) PREDICTED: pregnancy-s ( 333) 1605 243.2 7.4e-64 XP_016881635 (OMIM: 114890) PREDICTED: carcinoembr ( 617) 1520 231.3 5.3e-60 XP_011525288 (OMIM: 176397) PREDICTED: pregnancy-s ( 326) 1483 225.7 1.4e-58 XP_011525428 (OMIM: 176392) PREDICTED: pregnancy-s ( 357) 1483 225.7 1.5e-58 NP_001276971 (OMIM: 176396) putative pregnancy-spe ( 238) 1472 223.9 3.3e-58 NP_112536 (OMIM: 176391) pregnancy-specific beta-1 ( 335) 1463 222.8 1e-57 XP_011525429 (OMIM: 176392) PREDICTED: pregnancy-s ( 272) 1455 221.6 2e-57 NP_002776 (OMIM: 176401) pregnancy-specific beta-1 ( 335) 1455 221.7 2.3e-57 NP_998798 (OMIM: 176393) pregnancy-specific beta-1 ( 326) 1417 216.2 9.7e-56 XP_016882491 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1417 216.2 9.9e-56 NP_001288637 (OMIM: 176398) pregnancy-specific bet ( 333) 1369 209.3 1.2e-53 XP_005259132 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1369 209.4 1.3e-53 NP_001317453 (OMIM: 176390) pregnancy-specific bet ( 326) 1314 201.4 2.8e-51 XP_005259122 (OMIM: 176390) PREDICTED: pregnancy-s ( 333) 1314 201.4 2.8e-51 XP_016882489 (OMIM: 176393) PREDICTED: pregnancy-s ( 342) 1287 197.5 4.2e-50 XP_016882488 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1287 197.5 4.3e-50 NP_002772 (OMIM: 176394) pregnancy-specific beta-1 ( 335) 1194 184.2 4.3e-46 NP_001123486 (OMIM: 176394) pregnancy-specific bet ( 335) 1194 184.2 4.3e-46 XP_016882492 (OMIM: 176394) PREDICTED: pregnancy-s ( 335) 1194 184.2 4.3e-46 NP_001263424 (OMIM: 176393) pregnancy-specific bet ( 326) 1181 182.3 1.6e-45 XP_016882490 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1181 182.3 1.6e-45 NP_001288636 (OMIM: 176398) pregnancy-specific bet ( 333) 1132 175.3 2.1e-43 XP_016882494 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1132 175.3 2.4e-43 XP_016882487 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1129 174.9 2.9e-43 XP_016881687 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 961 150.6 4.3e-36 XP_011524643 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 961 150.6 4.3e-36 XP_011524644 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 961 150.6 4.3e-36 NP_001288638 (OMIM: 176398) pregnancy-specific bet ( 240) 826 131.2 2.8e-30 >>NP_001171754 (OMIM: 176390) pregnancy-specific beta-1- (419 aa) initn: 2827 init1: 2827 opt: 2827 Z-score: 2214.8 bits: 418.8 E(85289): 1.3e-116 Smith-Waterman score: 2827; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP 370 380 390 400 410 >>NP_008836 (OMIM: 176390) pregnancy-specific beta-1-gly (426 aa) initn: 2784 init1: 2784 opt: 2791 Z-score: 2186.7 bits: 413.6 E(85289): 4.6e-115 Smith-Waterman score: 2791; 99.0% identity (99.3% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::: .: NP_008 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSGKWIPA 370 380 390 400 410 420 NP_008 SLAIGF >>NP_001171755 (OMIM: 176390) pregnancy-specific beta-1- (417 aa) initn: 3105 init1: 2786 opt: 2786 Z-score: 2183.0 bits: 412.9 E(85289): 7.5e-115 Smith-Waterman score: 2786; 99.8% identity (100.0% similar) in 415 aa overlap (1-415:1-415) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP ::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSEAL 370 380 390 400 410 >>NP_001284702 (OMIM: 176390) pregnancy-specific beta-1- (428 aa) initn: 3105 init1: 2786 opt: 2786 Z-score: 2182.8 bits: 412.9 E(85289): 7.6e-115 Smith-Waterman score: 2786; 99.3% identity (99.8% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::: .. NP_001 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSAYSSSI 370 380 390 400 410 420 NP_001 NYTSGNRN >>NP_001123639 (OMIM: 176397) pregnancy-specific beta-1- (419 aa) initn: 2948 init1: 2624 opt: 2624 Z-score: 2057.2 bits: 389.6 E(85289): 7.6e-108 Smith-Waterman score: 2624; 92.8% identity (96.9% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :: :::::::::: ::::::::::::::: ::::::::::.::::::::::::::::::: NP_001 MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::.::::::::::::::.::::::::::::: ::::::::::::.:::::: NP_001 NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW ::::: : : .:::::.:::::.:::::::::::.:::::.::::::::::::::::::: NP_001 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::.: :.:::::::::::::::::::::::::::::::::::: ::::::::: NP_001 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP ::::::::::::::.:::::: :::::::::::::::::::::::::::::::::::::: NP_001 TRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP ::::::::: :::: :::::: .:::::::::.::::::::::::::::::.:::::.: NP_001 PAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSDWTLP 370 380 390 400 410 >>NP_874366 (OMIM: 176397) pregnancy-specific beta-1-gly (426 aa) initn: 2585 init1: 2585 opt: 2594 Z-score: 2033.8 bits: 385.3 E(85289): 1.5e-106 Smith-Waterman score: 2594; 92.1% identity (96.2% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :: :::::::::: ::::::::::::::: ::::::::::.::::::::::::::::::: NP_874 MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::.::::::::::::::.::::::::::::: ::::::::::::.:::::: NP_874 NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW ::::: : : .:::::.:::::.:::::::::::.:::::.::::::::::::::::::: NP_874 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::.: :.:::::::::::::::::::::::::::::::::::: ::::::::: NP_874 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 KPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP ::::::::::::::.:::::: :::::::::::::::::::::::::::::::::::::: NP_874 TRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP ::::::::: :::: :::::: .:::::::::.::::::::::::::::::.:: .: NP_874 PAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSGKRIPV 370 380 390 400 410 420 NP_874 SLAIGI >>NP_002774 (OMIM: 176396) putative pregnancy-specific b (419 aa) initn: 2871 init1: 2546 opt: 2546 Z-score: 1996.6 bits: 378.4 E(85289): 1.8e-104 Smith-Waterman score: 2546; 90.0% identity (95.7% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :: ::::::::.: ::::::::::::::: ::::::::::.: ::::::::::::::::: NP_002 MGPLSAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY :::::::::::.::::::.:::.:::.:: ::::::::::.::::::::::::.::.::: NP_002 NLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::: ::: ::::::::::.::::::::::::.::::. ::: :::::::::::::: NP_002 TLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::::::.::::::::.:.:::.::::::::::::::::::::::::::::::: NP_002 WMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV ::::::::::::::::: .::::::::::::::::::::::::::::: ::::::::::: NP_002 KPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP ::::::::::::::::::::::::::::::::::::::::::::.::. ::::: ::::: NP_002 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP ::::::::: :::: :::: : .:::::::::.:::::::::::::::.::.:::::.: NP_002 PAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRVSDWTLP 370 380 390 400 410 >>NP_066296 (OMIM: 176392) pregnancy-specific beta-1-gly (428 aa) initn: 2546 init1: 2546 opt: 2546 Z-score: 1996.5 bits: 378.5 E(85289): 1.8e-104 Smith-Waterman score: 2546; 91.5% identity (96.1% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :: :::::::::: :::::::: :::::::::::::::::::::::.::::::::::::: NP_066 MGPLSAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY ::.:::::::::.:::::::::::::.:::::::::::::.::::::::::::::::::: NP_066 NLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW ::::.: ::::: ::.:::::.::::::::::::: ::: ::::::::::::::::::: NP_066 TLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP :::::::::::::.::...:::::.::::::::::::::::::::::::::::::::::: NP_066 WMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_066 KPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP ::::::::::::.:::::::: ::::::::::::::::::::::.::: ::::: ::::: NP_066 TRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSFTYYHSGENLYLSCFADSNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP ::.:::::: :::: :::::: .:::::::::.::::::::: ::::::::.:: NP_066 PAEYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGMESSKSMTVKVSAPSGTG 370 380 390 400 410 420 NP_066 HLPGLNPL >>NP_002771 (OMIM: 176393) pregnancy-specific beta-1-gly (419 aa) initn: 2813 init1: 2489 opt: 2489 Z-score: 1952.4 bits: 370.3 E(85289): 5.2e-102 Smith-Waterman score: 2489; 88.5% identity (93.6% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :: :::::::::: :::.::::::::::: ::::::::::.: ::::::::::::::::: NP_002 MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY ::.::::::::: ::::::::::::. ::::::::::: .::::::::::::.:::::: NP_002 NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::: ::: ::::.:::::::::::::::::::::::.:::: ::::: :: ::: : NP_002 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP ::::::::::: :.::.::::::..::::: :::::::::::::::::::::::::::: NP_002 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV ::::::::::::::::::.:::::::.:::::::::::::::::::::::::::::::.: NP_002 KPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP ::::::::::::::::::::::::::::::::::: :::::::::::: ::::: :.::: NP_002 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP :::::::: :::: :::: : .:::::::::.:::::::::::::::.::.:::: .: NP_002 RAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSDWILP 370 380 390 400 410 >>XP_016882486 (OMIM: 176393) PREDICTED: pregnancy-speci (426 aa) initn: 2456 init1: 2456 opt: 2463 Z-score: 1932.1 bits: 366.5 E(85289): 7e-101 Smith-Waterman score: 2463; 88.1% identity (93.1% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KE0 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ :: :::::::::: :::.::::::::::: ::::::::::.: ::::::::::::::::: XP_016 MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY ::.::::::::: ::::::::::::. ::::::::::: .::::::::::::.:::::: XP_016 NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW :::::: ::: ::::.:::::::::::::::::::::::.:::: ::::: :: ::: : XP_016 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP ::::::::::: :.::.::::::..::::: :::::::::::::::::::::::::::: XP_016 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV ::::::::::::::::::.:::::::.:::::::::::::::::::::::::::::::.: XP_016 KPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP ::::::::::::::::::::::::::::::::::: :::::::::::: ::::: :.::: XP_016 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP :::::::: :::: :::: : .:::::::::.:::::::::::::::.::.:: .: XP_016 RAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSGKWIPA 370 380 390 400 410 420 XP_016 SLAIGI 419 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:14:09 2016 done: Thu Nov 3 05:14:11 2016 Total Scan time: 8.890 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]