FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0484, 226 aa 1>>>pF1KE0484 226 - 226 aa - 226 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2900+/-0.00116; mu= 5.4179+/- 0.069 mean_var=116.1782+/-23.307, 0's: 0 Z-trim(104.7): 19 B-trim: 55 in 1/51 Lambda= 0.118990 statistics sampled from 8046 (8051) to 8046 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.247), width: 16 Scan time: 1.870 The best scores are: opt bits E(32554) CCDS13745.1 ATP6V1E1 gene_id:529|Hs108|chr22 ( 226) 1427 255.7 1.7e-68 CCDS42977.1 ATP6V1E1 gene_id:529|Hs108|chr22 ( 204) 1229 221.7 2.7e-58 CCDS1826.1 ATP6V1E2 gene_id:90423|Hs108|chr2 ( 226) 1086 197.2 7.2e-51 CCDS42978.1 ATP6V1E1 gene_id:529|Hs108|chr22 ( 196) 720 134.3 5.2e-32 >>CCDS13745.1 ATP6V1E1 gene_id:529|Hs108|chr22 (226 aa) initn: 1427 init1: 1427 opt: 1427 Z-score: 1343.1 bits: 255.7 E(32554): 1.7e-68 Smith-Waterman score: 1427; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG 130 140 150 160 170 180 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD :::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 190 200 210 220 >>CCDS42977.1 ATP6V1E1 gene_id:529|Hs108|chr22 (204 aa) initn: 1229 init1: 1229 opt: 1229 Z-score: 1160.1 bits: 221.7 E(32554): 2.7e-58 Smith-Waterman score: 1236; 90.3% identity (90.3% similar) in 226 aa overlap (1-226:1-204) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK ::::::::::: ::::::::::::::::::::::::::: CCDS42 MALSDADVQKQ----------------------AEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG 100 110 120 130 140 150 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD :::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 160 170 180 190 200 >>CCDS1826.1 ATP6V1E2 gene_id:90423|Hs108|chr2 (226 aa) initn: 1103 init1: 1086 opt: 1086 Z-score: 1026.8 bits: 197.2 E(32554): 7.2e-51 Smith-Waterman score: 1086; 76.9% identity (89.8% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK :::::.::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MALSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::: ::.. :::::::::::.:::.:::.::: :::..:.: :: ::: :: CCDS18 EKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::: .:::: :::::: ::. ::.:::::::: : ... :.::::.:.:: . ::: CCDS18 LQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGG 130 140 150 160 170 180 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD ::.:.:...::::::::::::: :.: :::.: ::::::.::::. CCDS18 VEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI 190 200 210 220 >>CCDS42978.1 ATP6V1E1 gene_id:529|Hs108|chr22 (196 aa) initn: 695 init1: 678 opt: 720 Z-score: 688.2 bits: 134.3 E(32554): 5.2e-32 Smith-Waterman score: 1176; 86.7% identity (86.7% similar) in 226 aa overlap (1-226:1-196) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::::::::::::::::::::::::: CCDS42 EKQIEQQKKIQMSNLMNQARLKVLRARDDLIT---------------------------- 70 80 90 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 --GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG 100 110 120 130 140 150 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD :::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 160 170 180 190 226 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:04:26 2016 done: Thu Nov 3 05:04:26 2016 Total Scan time: 1.870 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]