FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0484, 226 aa 1>>>pF1KE0484 226 - 226 aa - 226 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1689+/-0.000484; mu= 6.3156+/- 0.030 mean_var=130.0218+/-26.156, 0's: 0 Z-trim(112.3): 4 B-trim: 224 in 1/53 Lambda= 0.112478 statistics sampled from 21164 (21167) to 21164 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.248), width: 16 Scan time: 4.690 The best scores are: opt bits E(85289) NP_001687 (OMIM: 108746) V-type proton ATPase subu ( 226) 1427 242.7 3.8e-64 NP_001034455 (OMIM: 108746) V-type proton ATPase s ( 204) 1229 210.6 1.6e-54 NP_001034456 (OMIM: 108746) V-type proton ATPase s ( 196) 720 127.9 1.2e-29 >>NP_001687 (OMIM: 108746) V-type proton ATPase subunit (226 aa) initn: 1427 init1: 1427 opt: 1427 Z-score: 1272.7 bits: 242.7 E(85289): 3.8e-64 Smith-Waterman score: 1427; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG 130 140 150 160 170 180 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD :::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 190 200 210 220 >>NP_001034455 (OMIM: 108746) V-type proton ATPase subun (204 aa) initn: 1229 init1: 1229 opt: 1229 Z-score: 1099.7 bits: 210.6 E(85289): 1.6e-54 Smith-Waterman score: 1236; 90.3% identity (90.3% similar) in 226 aa overlap (1-226:1-204) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK ::::::::::: ::::::::::::::::::::::::::: NP_001 MALSDADVQKQ----------------------AEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG 100 110 120 130 140 150 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD :::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 160 170 180 190 200 >>NP_001034456 (OMIM: 108746) V-type proton ATPase subun (196 aa) initn: 695 init1: 678 opt: 720 Z-score: 653.6 bits: 127.9 E(85289): 1.2e-29 Smith-Waterman score: 1176; 86.7% identity (86.7% similar) in 226 aa overlap (1-226:1-196) 10 20 30 40 50 60 pF1KE0 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV :::::::::::::::::::::::::::::::: NP_001 EKQIEQQKKIQMSNLMNQARLKVLRARDDLIT---------------------------- 70 80 90 130 140 150 160 170 180 pF1KE0 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 --GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG 100 110 120 130 140 150 190 200 210 220 pF1KE0 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD :::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 160 170 180 190 226 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:04:26 2016 done: Thu Nov 3 05:04:27 2016 Total Scan time: 4.690 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]