FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0487, 357 aa 1>>>pF1KE0487 357 - 357 aa - 357 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5236+/-0.000838; mu= 15.1316+/- 0.050 mean_var=62.5471+/-12.757, 0's: 0 Z-trim(106.2): 9 B-trim: 2 in 1/48 Lambda= 0.162170 statistics sampled from 8816 (8820) to 8816 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.271), width: 16 Scan time: 2.380 The best scores are: opt bits E(32554) CCDS14065.1 FAM118A gene_id:55007|Hs108|chr22 ( 357) 2372 563.5 9.7e-161 CCDS81647.1 FAM118B gene_id:79607|Hs108|chr11 ( 350) 1025 248.3 7.1e-66 CCDS8470.1 FAM118B gene_id:79607|Hs108|chr11 ( 351) 1025 248.3 7.1e-66 >>CCDS14065.1 FAM118A gene_id:55007|Hs108|chr22 (357 aa) initn: 2372 init1: 2372 opt: 2372 Z-score: 2999.2 bits: 563.5 E(32554): 9.7e-161 Smith-Waterman score: 2372; 99.4% identity (100.0% similar) in 357 aa overlap (1-357:1-357) 10 20 30 40 50 60 pF1KE0 MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIPALCSWRSCIEAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIPALCSWRSCIEAVI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKPSFFQDCLMEVFDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKPSFFQDCLMEVFDD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LEQHIRSPLVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPMESLDLKDKTKVLEWAR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LEQHIRSPVVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPMESLDLKDKTKVLEWAR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYRTKSFLFVGCGETLHD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS14 GHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYRTKSFLFVGCGETLRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKVVSYGDCFDHFPGYVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKVVSYGDCFDHFPGYVQ 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 DLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKKRTQSDTDDAGGS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKKRTQSDTDDAGGS 310 320 330 340 350 >>CCDS81647.1 FAM118B gene_id:79607|Hs108|chr11 (350 aa) initn: 1065 init1: 639 opt: 1025 Z-score: 1296.2 bits: 248.3 E(32554): 7.1e-66 Smith-Waterman score: 1025; 52.4% identity (81.1% similar) in 296 aa overlap (13-306:26-321) 10 20 30 40 pF1KE0 MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIP .: ::.: :: :.:.::.::::::.:::::: .: CCDS81 MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ALCSWRSCIEAVIEAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKP :: ::.. :.:...:: ....:. . .:.. . .:..:. ::::::.:.::::.... CCDS81 ALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 SFFQDCLMEVFDDLEQHIRSP--LVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPME .::.:::.:::::::..... .:::.: ::. ::.:::::.::::: .. :.: .: CCDS81 TFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SLDLKDKTKVLEWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYR :::: :. ::::::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::. CCDS81 SLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 TKSFLFVGCGETLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKV .:::::.::: :. : :::::: .: .: ::::.::: . . :.: : . .:: .:::: CCDS81 NKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKV 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 VSYGDCFDHFPGYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKK .:::: . .: : . :. .: CCDS81 ISYGDDYADLPEYFKRLTCEISTRGTSGMVREGQLNGSSAAHSEIRGCST 310 320 330 340 350 >>CCDS8470.1 FAM118B gene_id:79607|Hs108|chr11 (351 aa) initn: 1065 init1: 639 opt: 1025 Z-score: 1296.2 bits: 248.3 E(32554): 7.1e-66 Smith-Waterman score: 1025; 52.4% identity (81.1% similar) in 296 aa overlap (13-306:26-321) 10 20 30 40 pF1KE0 MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIP .: ::.: :: :.:.::.::::::.:::::: .: CCDS84 MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ALCSWRSCIEAVIEAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKP :: ::.. :.:...:: ....:. . .:.. . .:..:. ::::::.:.::::.... CCDS84 ALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 SFFQDCLMEVFDDLEQHIRSP--LVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPME .::.:::.:::::::..... .:::.: ::. ::.:::::.::::: .. :.: .: CCDS84 TFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SLDLKDKTKVLEWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYR :::: :. ::::::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::. CCDS84 SLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 TKSFLFVGCGETLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKV .:::::.::: :. : :::::: .: .: ::::.::: . . :.: : . .:: .:::: CCDS84 NKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKV 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 VSYGDCFDHFPGYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKK .:::: . .: : . :. .: CCDS84 ISYGDDYADLPEYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST 310 320 330 340 350 357 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:52:06 2016 done: Thu Nov 3 04:52:07 2016 Total Scan time: 2.380 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]