FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0488, 369 aa
  1>>>pF1KE0488 369 - 369 aa - 369 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5900+/-0.000826; mu= 14.7990+/- 0.050
 mean_var=69.8883+/-13.500, 0's: 0 Z-trim(107.9): 12  B-trim: 0 in 0/51
 Lambda= 0.153416
 statistics sampled from 9858 (9863) to 9858 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.303), width:  16
 Scan time:  2.570

The best scores are:                                      opt bits E(32554)
CCDS13834.2 ASPHD2 gene_id:57168|Hs108|chr22       ( 369) 2644 594.2 5.8e-170
CCDS10660.1 ASPHD1 gene_id:253982|Hs108|chr16      ( 390)  994 229.0 5.3e-60
CCDS55234.1 ASPH gene_id:444|Hs108|chr8            ( 729)  365 89.9 7.3e-18
CCDS34898.1 ASPH gene_id:444|Hs108|chr8            ( 758)  365 90.0 7.6e-18


>>CCDS13834.2 ASPHD2 gene_id:57168|Hs108|chr22            (369 aa)
 initn: 2644 init1: 2644 opt: 2644  Z-score: 3164.8  bits: 594.2 E(32554): 5.8e-170
Smith-Waterman score: 2644; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)

               10        20        30        40        50        60
pF1KE0 MVWAPLGPPRTDCLTLLHTPSKDSPKMSLEWLVAWSWSLDGLRDCIATGIQSVRDCDTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MVWAPLGPPRTDCLTLLHTPSKDSPKMSLEWLVAWSWSLDGLRDCIATGIQSVRDCDTTA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 VITVACLLVLFVWYCYHVGREQPRPYVSVNSLMQAADANGLQNGYVYCQSPECVRCTHNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VITVACLLVLFVWYCYHVGREQPRPYVSVNSLMQAADANGLQNGYVYCQSPECVRCTHNE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 RDAQKHDVEVLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RDAQKHDVEVLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 NGCELVVGGEPQCWAEGRCLLFDDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NGCELVVGGEPQCWAEGRCLLFDDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQA
              310       320       330       340       350       360

                
pF1KE0 LDFIFAPGR
       :::::::::
CCDS13 LDFIFAPGR
                

>>CCDS10660.1 ASPHD1 gene_id:253982|Hs108|chr16           (390 aa)
 initn: 938 init1: 683 opt: 994  Z-score: 1190.7  bits: 229.0 E(32554): 5.3e-60
Smith-Waterman score: 994; 49.8% identity (72.4% similar) in 315 aa overlap (67-367:87-388)

         40        50        60        70        80        90      
pF1KE0 WSLDGLRDCIATGIQSVRDCDTTAVITVACLLVLFVWYCYHVGREQPRPYVSVNSLMQAA
                                     :  ::.::::..: ..      ...:  ..
CCDS10 APGLLARASLIMLPWPLPLASSALTLLFGALTSLFLWYCYRLGSQD------MQALGAGS
         60        70        80        90       100             110

        100            110           120       130       140       
pF1KE0 DANGLQNGYVYCQ-----SP----ECVRCTHNEGLNQKLYHNLQEYAKRYSWSGMGRIHK
        :.:...: : :.     ::    .  .  ..::: ..    :. ::.::::.::::...
CCDS10 RAGGVRGGPVGCSEAGGPSPGGPGDPGEGPRTEGLVSR---RLRAYARRYSWAGMGRVRR
              120       130       140          150       160       

       150        160          170       180       190       200   
pF1KE0 GIREQGRYLNSR-PS---IQKPEVFFLPDLPTTPYFSRDAQKHDVEVLERNFQTILCEFE
       .   ::    .: :.   ::.: ..::::::..:.  ::::.::::.:: .: .:: .: 
CCDS10 A--AQGGPGPGRGPGVLGIQRPGLLFLPDLPSAPFVPRDAQRHDVELLESSFPAILRDFG
         170       180       190       200       210       220     

           210        220       230       240       250       260  
pF1KE0 TLYKAFSNCSLP-QGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIG
       ..   ::. . : .::.   .:.   . . : . : : : :::.:: .:: : .::. ..
CCDS10 AVSWDFSGTTPPPRGWSPPLAPGC--YQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMS
         230       240         250       260       270       280   

            270       280       290       300       310       320  
pF1KE0 NNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLF
        :.:::: .::: ::. .  . :::: :.::::::: : ::::::::::::::::.::: 
CCDS10 ANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLV
           290       300       310       320       330       340   

            330       340       350       360         
pF1KE0 DDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR
       ::::::.. :.:: ::::::::.:::::::::.::::::::.:::  
CCDS10 DDSFLHTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP
           350       360       370       380       390

>>CCDS55234.1 ASPH gene_id:444|Hs108|chr8                 (729 aa)
 initn: 281 init1: 116 opt: 365  Z-score: 434.1  bits: 89.9 E(32554): 7.3e-18
Smith-Waterman score: 370; 30.1% identity (56.2% similar) in 249 aa overlap (125-364:497-729)

          100       110       120       130             140        
pF1KE0 AADANGLQNGYVYCQSPECVRCTHNEGLNQKLYHNLQEYAKR------YSWSGMGRIHKG
                                     ..: .: .  .:      :.:  .:  :: 
CCDS55 FILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELG--HK-
        470       480       490       500       510       520      

      150       160       170       180         190       200      
pF1KE0 IREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHD--VEVLERNFQTILCEFETLY
          .:..     :. .  .. .  : . :...     .   :. ::::.. :  :  ...
CCDS55 ---RGHF----ASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAVM
                  530       540       550       560       570      

        210       220       230       240       250       260      
pF1KE0 KAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVF
          ..  ::.    :   .:.:  : : .::      :.  :.:  :: ..    :    
CCDS55 DKAKGLFLPED--ENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRR-
        580         590       600       610       620       630    

        270       280       290       300        310       320     
pF1KE0 GNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPN-GCELVVGGEPQCWAEGRCLLFDDS
       :.   :.. ::: .  : :::: :.: ::::  :. ::..  ..: . : ::. :.::::
CCDS55 GQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFDDS
           640       650       660       670       680       690   

         330       340       350       360         
pF1KE0 FLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR
       : : .....:.    :..:.::.:::...  .:..:  :     
CCDS55 FEHEVWQDASSF---RLIFIVDVWHPELTPQQRRSLPAI     
           700          710       720              

>>CCDS34898.1 ASPH gene_id:444|Hs108|chr8                 (758 aa)
 initn: 281 init1: 116 opt: 365  Z-score: 433.9  bits: 90.0 E(32554): 7.6e-18
Smith-Waterman score: 370; 30.1% identity (56.2% similar) in 249 aa overlap (125-364:526-758)

          100       110       120       130             140        
pF1KE0 AADANGLQNGYVYCQSPECVRCTHNEGLNQKLYHNLQEYAKR------YSWSGMGRIHKG
                                     ..: .: .  .:      :.:  .:  :: 
CCDS34 FILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELG--HK-
         500       510       520       530       540       550     

      150       160       170       180         190       200      
pF1KE0 IREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHD--VEVLERNFQTILCEFETLY
          .:..     :. .  .. .  : . :...     .   :. ::::.. :  :  ...
CCDS34 ---RGHF----ASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAVM
                   560       570       580       590       600     

        210       220       230       240       250       260      
pF1KE0 KAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVF
          ..  ::.    :   .:.:  : : .::      :.  :.:  :: ..    :    
CCDS34 DKAKGLFLPED--ENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRR-
         610         620       630       640       650       660   

        270       280       290       300        310       320     
pF1KE0 GNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPN-GCELVVGGEPQCWAEGRCLLFDDS
       :.   :.. ::: .  : :::: :.: ::::  :. ::..  ..: . : ::. :.::::
CCDS34 GQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFDDS
            670       680       690       700       710       720  

         330       340       350       360         
pF1KE0 FLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR
       : : .....:.    :..:.::.:::...  .:..:  :     
CCDS34 FEHEVWQDASSF---RLIFIVDVWHPELTPQQRRSLPAI     
            730          740       750             




369 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:45:02 2016 done: Thu Nov  3 04:45:03 2016
 Total Scan time:  2.570 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]