FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0490, 407 aa 1>>>pF1KE0490 407 - 407 aa - 407 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5115+/-0.000862; mu= 16.4848+/- 0.052 mean_var=69.3285+/-13.768, 0's: 0 Z-trim(106.8): 18 B-trim: 3 in 1/50 Lambda= 0.154035 statistics sampled from 9207 (9211) to 9207 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.283), width: 16 Scan time: 2.880 The best scores are: opt bits E(32554) CCDS13969.2 TMEM184B gene_id:25829|Hs108|chr22 ( 407) 2732 616.1 1.9e-176 CCDS43537.1 TMEM184A gene_id:202915|Hs108|chr7 ( 413) 1752 398.3 6.8e-111 CCDS3770.1 TMEM184C gene_id:55751|Hs108|chr4 ( 438) 645 152.3 8.1e-37 >>CCDS13969.2 TMEM184B gene_id:25829|Hs108|chr22 (407 aa) initn: 2732 init1: 2732 opt: 2732 Z-score: 3281.4 bits: 616.1 E(32554): 1.9e-176 Smith-Waterman score: 2732; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KE0 MTVRGDVLAPDPASPTTAAASPSVSVIPEGSPTAMEQPVFLMTTAAQAISGFFVWTALLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MTVRGDVLAPDPASPTTAAASPSVSVIPEGSPTAMEQPVFLMTTAAQAISGFFVWTALLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIGFLRFCKQATLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIGFLRFCKQATLQF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 CVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 CVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSARVSVGEGTVAAGYQDFIIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSARVSVGEGTVAAGYQDFIIC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 VEMFFAALALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VEMFFAALALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPA 310 320 330 340 350 360 370 380 390 400 pF1KE0 YQQYTQQSTLEPGPTWRGGAHGLSRSHSLSGARDNEKTLLLSSDDEF ::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YQQYTQQSTLEPGPTWRGGAHGLSRSHSLSGARDNEKTLLLSSDDEF 370 380 390 400 >>CCDS43537.1 TMEM184A gene_id:202915|Hs108|chr7 (413 aa) initn: 1705 init1: 1308 opt: 1752 Z-score: 2104.3 bits: 398.3 E(32554): 6.8e-111 Smith-Waterman score: 1752; 64.6% identity (87.0% similar) in 401 aa overlap (10-405:21-412) 10 20 30 40 pF1KE0 MTVRGDVLAPDPASPTTAAASPSVSVIPEGSPTAMEQPVFLMTTA-AQA :.:. : .. :.:... . ..: : : ...:.: :.. CCDS43 MSNVSGILETAGVPLVSANWPQPSPPPAVPAGPQMDHMGNSSQGA---PWLFLTSALARG 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 ISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYY .::.::::::..::::::.::: :. :.:::::.:.:.::::::::::::::.. . ::: CCDS43 VSGIFVWTALVLTCHQIYLHLRSYTVPQEQRYIIRLLLIVPIYAFDSWLSLLLLGDHQYY 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 VYFGTVRDCYEALVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIG ::: .:::::::.:::.:::::..:::::..::.:::::::.:::.:::::: : ::::: CCDS43 VYFDSVRDCYEAFVIYSFLSLCFQYLGGEGAIMAEIRGKPIKSSCLYGTCCLRGMTYSIG 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 FLRFCKQATLQFCVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYA :::::::::::::.:::.:::.:..:::::::.::::.: :::::::.::: :::::::: CCDS43 FLRFCKQATLQFCLVKPVMAVTTIILQAFGKYHDGDFNVRSGYLYVTLIYNASVSLALYA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIH-SARVSVGE ::::::.::::: :..:::::. .:.:::::::::.::::::.::.::... :. ..: CCDS43 LFLFYFTTRELLRPFQPVLKFLTIKAVIFLSFWQGLLLAILERCGVIPEVETSGGNKLGA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 GTVAAGYQDFIICVEMFFAALALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPH ::.:::::.:::::::.::..:::.:: .:::.:. .. . :::.::::...::..:. CCDS43 GTLAAGYQNFIICVEMLFASVALRYAFPCQVYAEKKENSPAPPAPMQSISSGIRETVSPQ 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 DIVQDAIHNFSPAYQQYTQQSTLE---PGPTWRGGAHGLSRSHSLSGARDNEKTLLLSSD :::::::::::::::.::::.: : :: ::. : .:.:: :: .:. :. CCDS43 DIVQDAIHNFSPAYQHYTQQATHEAPRPGTHPSGGSGGSRKSRSL------EKRMLIPSE 360 370 380 390 400 410 pF1KE0 DEF : CCDS43 DL >>CCDS3770.1 TMEM184C gene_id:55751|Hs108|chr4 (438 aa) initn: 628 init1: 368 opt: 645 Z-score: 774.4 bits: 152.3 E(32554): 8.1e-37 Smith-Waterman score: 645; 37.7% identity (68.9% similar) in 289 aa overlap (44-330:46-326) 20 30 40 50 60 70 pF1KE0 SPTTAAASPSVSVIPEGSPTAMEQPVFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYS : : :.:.:. .. :. : .:: :. CCDS37 PLVAVIYLVSIVVAVPLCVWELQKLEVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYT 20 30 40 50 60 70 80 90 100 110 120 130 pF1KE0 CPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEALVIYNFLSLCYEY :. :. :.:::..::::..:::..: . .: : :.:::: :::::... .: CCDS37 QPELQKPIIRILWMVPIYSLDSWIALKY---PGIAIYVDTCRECYEAYVIYNFMGFLTNY 80 90 100 110 120 130 140 150 160 170 180 190 pF1KE0 LGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIG--FLRFCKQATLQFCVVKPLMAVST : .. . : ... . :: ...: .: :: ..::. ::.:. .. . CCDS37 LTNRYPNLVLILEAKDQQKHFPPLCCC--PPWAMGEVLLFRCKLGVLQYTVVRPFTTIVA 140 150 160 170 180 190 200 210 220 230 240 250 pF1KE0 VVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFM .. . .: : .:.:. .... :..:: :.: .:.: :.::: . .: ::: .:: ::. CCDS37 LICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFLC 200 210 220 230 240 250 260 270 280 290 300 310 pF1KE0 VKSVIFLSFWQGMLLAILEKCGAIPKIHSARVSVGEGTVAAGYQDFIICVEMFFAALALR :: :.:.::::....:.: : :.: . :. . .. :. ::.: ::::::.:::.::.: . CCDS37 VKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEA-VATGLQDFIICIEMFLAAIAHH 260 270 280 290 300 320 330 340 350 360 370 pF1KE0 HAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLE ..:.:: :... .: : CCDS37 YTFSYKPYVQEA--EEGSCFDSFLAMWDVSDIRDDISEQVRHVGRTVRGHPRKKLFPEDQ 310 320 330 340 350 360 407 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:38:28 2016 done: Thu Nov 3 04:38:28 2016 Total Scan time: 2.880 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]