Result of FASTA (omim) for
pF1KE0507
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0507, 259 aa
1>>>pF1KE0507 259 - 259 aa - 259 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2928+/-0.000274; mu= 15.8022+/- 0.017
mean_var=77.2498+/-15.572, 0's: 0 Z-trim(120.2): 67 B-trim: 566 in 1/53
Lambda= 0.145924
statistics sampled from 34966 (35039) to 34966 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.411), width: 16
Scan time: 6.790
The best scores are: opt bits E(85289)
XP_005261430 (OMIM: 614240) PREDICTED: sesquipedal ( 259) 1799 387.4 1.4e-107
NP_001002034 (OMIM: 614240) sesquipedalian-2 [Homo ( 259) 1799 387.4 1.4e-107
XP_016874372 (OMIM: 614239) PREDICTED: sesquipedal ( 249) 482 110.1 4e-24
NP_001171468 (OMIM: 614239) sesquipedalian-1 isofo ( 249) 482 110.1 4e-24
XP_011536278 (OMIM: 614239) PREDICTED: sesquipedal ( 249) 482 110.1 4e-24
XP_006719320 (OMIM: 614239) PREDICTED: sesquipedal ( 249) 482 110.1 4e-24
NP_653272 (OMIM: 614239) sesquipedalian-1 isoform ( 249) 482 110.1 4e-24
NP_001171467 (OMIM: 614239) sesquipedalian-1 isofo ( 262) 482 110.1 4.1e-24
>>XP_005261430 (OMIM: 614240) PREDICTED: sesquipedalian- (259 aa)
initn: 1799 init1: 1799 opt: 1799 Z-score: 2052.3 bits: 387.4 E(85289): 1.4e-107
Smith-Waterman score: 1799; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
190 200 210 220 230 240
250
pF1KE0 CWQKRAQGSHSKCEEQDRP
:::::::::::::::::::
XP_005 CWQKRAQGSHSKCEEQDRP
250
>>NP_001002034 (OMIM: 614240) sesquipedalian-2 [Homo sap (259 aa)
initn: 1799 init1: 1799 opt: 1799 Z-score: 2052.3 bits: 387.4 E(85289): 1.4e-107
Smith-Waterman score: 1799; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
190 200 210 220 230 240
250
pF1KE0 CWQKRAQGSHSKCEEQDRP
:::::::::::::::::::
NP_001 CWQKRAQGSHSKCEEQDRP
250
>>XP_016874372 (OMIM: 614239) PREDICTED: sesquipedalian- (249 aa)
initn: 522 init1: 211 opt: 482 Z-score: 554.1 bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
:::::::.: :: :.:.:. ::: :: .. :: ::::.::.:: ::. .
XP_016 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
: :.....::::::::.:: ::::::. : . .: ..::::. :.:.:::.:::::
XP_016 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
: :.::::::::.:: .: . .. . . . : :. .: : : . .
XP_016 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
120 130 140 150 160
190 200 210 220
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
:: . :: : : : .. : ....: .: . . :. :
XP_016 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
170 180 190 200 210 220
230 240 250
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
:. ::::: :: : ..:.:
XP_016 HECYGQEIRALRGQWLSSRVQP
230 240
>>NP_001171468 (OMIM: 614239) sesquipedalian-1 isoform 2 (249 aa)
initn: 522 init1: 211 opt: 482 Z-score: 554.1 bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
:::::::.: :: :.:.:. ::: :: .. :: ::::.::.:: ::. .
NP_001 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
: :.....::::::::.:: ::::::. : . .: ..::::. :.:.:::.:::::
NP_001 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
: :.::::::::.:: .: . .. . . . : :. .: : : . .
NP_001 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
120 130 140 150 160
190 200 210 220
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
:: . :: : : : .. : ....: .: . . :. :
NP_001 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
170 180 190 200 210 220
230 240 250
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
:. ::::: :: : ..:.:
NP_001 HECYGQEIRALRGQWLSSRVQP
230 240
>>XP_011536278 (OMIM: 614239) PREDICTED: sesquipedalian- (249 aa)
initn: 522 init1: 211 opt: 482 Z-score: 554.1 bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
:::::::.: :: :.:.:. ::: :: .. :: ::::.::.:: ::. .
XP_011 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
: :.....::::::::.:: ::::::. : . .: ..::::. :.:.:::.:::::
XP_011 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
: :.::::::::.:: .: . .. . . . : :. .: : : . .
XP_011 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
120 130 140 150 160
190 200 210 220
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
:: . :: : : : .. : ....: .: . . :. :
XP_011 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
170 180 190 200 210 220
230 240 250
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
:. ::::: :: : ..:.:
XP_011 HECYGQEIRALRGQWLSSRVQP
230 240
>>XP_006719320 (OMIM: 614239) PREDICTED: sesquipedalian- (249 aa)
initn: 522 init1: 211 opt: 482 Z-score: 554.1 bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
:::::::.: :: :.:.:. ::: :: .. :: ::::.::.:: ::. .
XP_006 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
: :.....::::::::.:: ::::::. : . .: ..::::. :.:.:::.:::::
XP_006 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
: :.::::::::.:: .: . .. . . . : :. .: : : . .
XP_006 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
120 130 140 150 160
190 200 210 220
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
:: . :: : : : .. : ....: .: . . :. :
XP_006 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
170 180 190 200 210 220
230 240 250
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
:. ::::: :: : ..:.:
XP_006 HECYGQEIRALRGQWLSSRVQP
230 240
>>NP_653272 (OMIM: 614239) sesquipedalian-1 isoform 2 [H (249 aa)
initn: 522 init1: 211 opt: 482 Z-score: 554.1 bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)
10 20 30 40 50 60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
:::::::.: :: :.:.:. ::: :: .. :: ::::.::.:: ::. .
NP_653 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
: :.....::::::::.:: ::::::. : . .: ..::::. :.:.:::.:::::
NP_653 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
: :.::::::::.:: .: . .. . . . : :. .: : : . .
NP_653 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
120 130 140 150 160
190 200 210 220
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
:: . :: : : : .. : ....: .: . . :. :
NP_653 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
170 180 190 200 210 220
230 240 250
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
:. ::::: :: : ..:.:
NP_653 HECYGQEIRALRGQWLSSRVQP
230 240
>>NP_001171467 (OMIM: 614239) sesquipedalian-1 isoform 1 (262 aa)
initn: 522 init1: 211 opt: 482 Z-score: 553.8 bits: 110.1 E(85289): 4.1e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:14-261)
10 20 30 40
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVL
:::::::.: :: :.:.:. ::: :: .. :: ::::
NP_001 MAPGSPPGPAIATMKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVL
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 KGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPA
.::.:: ::. .: :.....::::::::.:: ::::::. : . .: ..::::.
NP_001 RGNMLFYFEDAASREPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 AQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAA
:.:.:::.:::::: :.::::::::.:: .: . .. . . . : :. .:
NP_001 AMEGWVKALSRASFDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA
120 130 140 150 160
170 180 190 200 210
pF1KE0 GLENGHCLSKDSSPVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQS
: : . .:: . :: : : : .. : ....
NP_001 -LAPVPSLPSAPAPVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASA
170 180 190 200 210 220
220 230 240 250
pF1KE0 PVSP-ETSCFSTLHDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
: .: . . :. ::. ::::: :: : ..:.:
NP_001 PHGPLDMAPFARLHECYGQEIRALRGQWLSSRVQP
230 240 250 260
259 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:43:18 2016 done: Thu Nov 3 03:43:19 2016
Total Scan time: 6.790 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]