FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0510, 235 aa 1>>>pF1KE0510 235 - 235 aa - 235 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5034+/-0.000296; mu= 15.4642+/- 0.019 mean_var=92.5409+/-18.831, 0's: 0 Z-trim(119.0): 7 B-trim: 0 in 0/55 Lambda= 0.133324 statistics sampled from 32635 (32642) to 32635 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.383), width: 16 Scan time: 5.360 The best scores are: opt bits E(85289) NP_741999 (OMIM: 608142) iron-sulfur cluster co-ch ( 235) 1620 320.8 1.3e-87 NP_001305243 (OMIM: 608142) iron-sulfur cluster co ( 150) 1045 210.0 1.8e-54 NP_001305244 (OMIM: 608142) iron-sulfur cluster co ( 143) 1041 209.3 2.9e-54 XP_005261416 (OMIM: 608142) PREDICTED: iron-sulfur ( 223) 985 198.7 7.1e-51 XP_016884109 (OMIM: 608142) PREDICTED: iron-sulfur ( 79) 480 101.1 5.7e-22 XP_016884108 (OMIM: 608142) PREDICTED: iron-sulfur ( 79) 480 101.1 5.7e-22 NP_001305245 (OMIM: 608142) iron-sulfur cluster co ( 79) 480 101.1 5.7e-22 >>NP_741999 (OMIM: 608142) iron-sulfur cluster co-chaper (235 aa) initn: 1620 init1: 1620 opt: 1620 Z-score: 1694.2 bits: 320.8 E(85289): 1.3e-87 Smith-Waterman score: 1620; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235) 10 20 30 40 50 60 pF1KE0 MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 STLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 STLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAA 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 MKEIESIVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 MKEIESIVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL 190 200 210 220 230 >>NP_001305243 (OMIM: 608142) iron-sulfur cluster co-cha (150 aa) initn: 1045 init1: 1045 opt: 1045 Z-score: 1099.0 bits: 210.0 E(85289): 1.8e-54 Smith-Waterman score: 1045; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KE0 MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 STLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAA :::::::::::::::::::::: NP_001 STLVNDAYKTLLAPLSRGLYLLNRKNLLTM 130 140 150 >>NP_001305244 (OMIM: 608142) iron-sulfur cluster co-cha (143 aa) initn: 1041 init1: 1041 opt: 1041 Z-score: 1095.2 bits: 209.3 E(85289): 2.9e-54 Smith-Waterman score: 1041; 99.3% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KE0 MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 STLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAA :::::::::::::::::::::. NP_001 STLVNDAYKTLLAPLSRGLYLVS 130 140 >>XP_005261416 (OMIM: 608142) PREDICTED: iron-sulfur clu (223 aa) initn: 985 init1: 985 opt: 985 Z-score: 1034.4 bits: 198.7 E(85289): 7.1e-51 Smith-Waterman score: 985; 100.0% identity (100.0% similar) in 156 aa overlap (80-235:68-223) 50 60 70 80 90 100 pF1KE0 PGREDRFFCPQCRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQR :::::::::::::::::::::::::::::: XP_005 HLTPLETTSALWTGTSDGFGKRARARDTSSNRSFRVDTAKLQHRYQQLQRLVHPDFFSQR 40 50 60 70 80 90 110 120 130 140 150 160 pF1KE0 SQTEKDFSEKHSTLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQTEKDFSEKHSTLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEIN 100 110 120 130 140 150 170 180 190 200 210 220 pF1KE0 EKLAEAESEAAMKEIESIVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLAEAESEAAMKEIESIVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIK 160 170 180 190 200 210 230 pF1KE0 LKKIPL :::::: XP_005 LKKIPL 220 >>XP_016884109 (OMIM: 608142) PREDICTED: iron-sulfur clu (79 aa) initn: 480 init1: 480 opt: 480 Z-score: 515.4 bits: 101.1 E(85289): 5.7e-22 Smith-Waterman score: 480; 100.0% identity (100.0% similar) in 79 aa overlap (157-235:1-79) 130 140 150 160 170 180 pF1KE0 AYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAAMKEIES :::::::::::::::::::::::::::::: XP_016 MDRQFLIEIMEINEKLAEAESEAAMKEIES 10 20 30 190 200 210 220 230 pF1KE0 IVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL 40 50 60 70 >>XP_016884108 (OMIM: 608142) PREDICTED: iron-sulfur clu (79 aa) initn: 480 init1: 480 opt: 480 Z-score: 515.4 bits: 101.1 E(85289): 5.7e-22 Smith-Waterman score: 480; 100.0% identity (100.0% similar) in 79 aa overlap (157-235:1-79) 130 140 150 160 170 180 pF1KE0 AYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAAMKEIES :::::::::::::::::::::::::::::: XP_016 MDRQFLIEIMEINEKLAEAESEAAMKEIES 10 20 30 190 200 210 220 230 pF1KE0 IVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL 40 50 60 70 >>NP_001305245 (OMIM: 608142) iron-sulfur cluster co-cha (79 aa) initn: 480 init1: 480 opt: 480 Z-score: 515.4 bits: 101.1 E(85289): 5.7e-22 Smith-Waterman score: 480; 100.0% identity (100.0% similar) in 79 aa overlap (157-235:1-79) 130 140 150 160 170 180 pF1KE0 AYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAAMKEIES :::::::::::::::::::::::::::::: NP_001 MDRQFLIEIMEINEKLAEAESEAAMKEIES 10 20 30 190 200 210 220 230 pF1KE0 IVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL 40 50 60 70 235 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:09:16 2016 done: Thu Nov 3 03:09:17 2016 Total Scan time: 5.360 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]