FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0512, 285 aa 1>>>pF1KE0512 285 - 285 aa - 285 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7991+/-0.000332; mu= 18.0577+/- 0.021 mean_var=65.4684+/-13.614, 0's: 0 Z-trim(115.6): 9 B-trim: 12 in 1/48 Lambda= 0.158511 statistics sampled from 26149 (26157) to 26149 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.307), width: 16 Scan time: 5.840 The best scores are: opt bits E(85289) NP_060054 (OMIM: 606774) inositol oxygenase [Homo ( 285) 2048 476.9 2e-134 XP_005261982 (OMIM: 606774) PREDICTED: inositol ox ( 239) 1742 406.8 2e-113 XP_011529007 (OMIM: 606774) PREDICTED: inositol ox ( 221) 764 183.1 4e-46 >>NP_060054 (OMIM: 606774) inositol oxygenase [Homo sapi (285 aa) initn: 2048 init1: 2048 opt: 2048 Z-score: 2534.5 bits: 476.9 E(85289): 2e-134 Smith-Waterman score: 2048; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285) 10 20 30 40 50 60 pF1KE0 MKVTVGPDPSLVYRPDVDPEVAKDKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MKVTVGPDPSLVYRPDVDPEVAKDKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AQFGGFSYKKMTVMEAVDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AQFGGFSYKKMTVMEAVDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LLHDLGKVLALFGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LLHDLGKVLALFGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PHCGLDRVLMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PHCGLDRVLMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDL 190 200 210 220 230 240 250 260 270 280 pF1KE0 AMLPWVREFNKFDLYTKCPDLPDVDKLRPYYQGLIDKYCPGILSW ::::::::::::::::::::::::::::::::::::::::::::: NP_060 AMLPWVREFNKFDLYTKCPDLPDVDKLRPYYQGLIDKYCPGILSW 250 260 270 280 >>XP_005261982 (OMIM: 606774) PREDICTED: inositol oxygen (239 aa) initn: 1742 init1: 1742 opt: 1742 Z-score: 2157.4 bits: 406.8 E(85289): 2e-113 Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 239 aa overlap (47-285:1-239) 20 30 40 50 60 70 pF1KE0 VDPEVAKDKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKHAQFGGFSYKKMTVMEA :::::::::::::::::::::::::::::: XP_005 MHTHQTVDFVRSKHAQFGGFSYKKMTVMEA 10 20 30 80 90 100 110 120 130 pF1KE0 VDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALFGEPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALFGEPQ 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 WAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRVLMSWGHDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRVLMSWGHDE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 YMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDLAMLPWVREFNKFDLYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDLAMLPWVREFNKFDLYT 160 170 180 190 200 210 260 270 280 pF1KE0 KCPDLPDVDKLRPYYQGLIDKYCPGILSW ::::::::::::::::::::::::::::: XP_005 KCPDLPDVDKLRPYYQGLIDKYCPGILSW 220 230 >>XP_011529007 (OMIM: 606774) PREDICTED: inositol oxygen (221 aa) initn: 764 init1: 764 opt: 764 Z-score: 949.1 bits: 183.1 E(85289): 4e-46 Smith-Waterman score: 764; 100.0% identity (100.0% similar) in 113 aa overlap (1-113:1-113) 10 20 30 40 50 60 pF1KE0 MKVTVGPDPSLVYRPDVDPEVAKDKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKVTVGPDPSLVYRPDVDPEVAKDKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AQFGGFSYKKMTVMEAVDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVG ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQFGGFSYKKMTVMEAVDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKVPNLPCP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LLHDLGKVLALFGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQ XP_011 SPSQTGSTSSGSCTTWGRSWPCSGSPSGRSSATPSPTSPTAPHGCLSLLSLLSLPSLPSL 130 140 150 160 170 180 285 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:00:20 2016 done: Thu Nov 3 03:00:21 2016 Total Scan time: 5.840 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]