FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0513, 331 aa 1>>>pF1KE0513 331 - 331 aa - 331 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9828+/-0.000337; mu= 12.6181+/- 0.021 mean_var=77.1084+/-14.860, 0's: 0 Z-trim(115.4): 49 B-trim: 229 in 2/54 Lambda= 0.146057 statistics sampled from 25811 (25860) to 25811 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.303), width: 16 Scan time: 6.140 The best scores are: opt bits E(85289) NP_001131077 (OMIM: 608122) gamma-parvin [Homo sap ( 331) 2133 458.8 7.3e-129 XP_005261759 (OMIM: 608122) PREDICTED: gamma-parvi ( 331) 2133 458.8 7.3e-129 NP_071424 (OMIM: 608122) gamma-parvin [Homo sapien ( 331) 2133 458.8 7.3e-129 XP_011528604 (OMIM: 608122) PREDICTED: gamma-parvi ( 398) 2133 458.8 8.6e-129 XP_016884396 (OMIM: 608122) PREDICTED: gamma-parvi ( 317) 1816 392.0 9e-109 XP_016884397 (OMIM: 608122) PREDICTED: gamma-parvi ( 317) 1816 392.0 9e-109 XP_005261653 (OMIM: 608121) PREDICTED: beta-parvin ( 312) 863 191.2 2.5e-48 NP_001230314 (OMIM: 608121) beta-parvin isoform c ( 327) 863 191.2 2.6e-48 NP_037459 (OMIM: 608121) beta-parvin isoform b [Ho ( 364) 863 191.2 2.9e-48 NP_001003828 (OMIM: 608121) beta-parvin isoform a ( 397) 863 191.2 3.1e-48 XP_005253072 (OMIM: 608120) PREDICTED: alpha-parvi ( 328) 850 188.4 1.8e-47 NP_060692 (OMIM: 608120) alpha-parvin [Homo sapien ( 412) 850 188.5 2.1e-47 NP_001230315 (OMIM: 608121) beta-parvin isoform d ( 289) 513 117.4 3.7e-26 XP_016884281 (OMIM: 608121) PREDICTED: beta-parvin ( 341) 513 117.4 4.3e-26 >>NP_001131077 (OMIM: 608122) gamma-parvin [Homo sapiens (331 aa) initn: 2133 init1: 2133 opt: 2133 Z-score: 2434.5 bits: 458.8 E(85289): 7.3e-129 Smith-Waterman score: 2133; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 250 260 270 280 290 300 310 320 330 pF1KE0 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN ::::::::::::::::::::::::::::::: NP_001 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 310 320 330 >>XP_005261759 (OMIM: 608122) PREDICTED: gamma-parvin is (331 aa) initn: 2133 init1: 2133 opt: 2133 Z-score: 2434.5 bits: 458.8 E(85289): 7.3e-129 Smith-Waterman score: 2133; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 250 260 270 280 290 300 310 320 330 pF1KE0 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN ::::::::::::::::::::::::::::::: XP_005 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 310 320 330 >>NP_071424 (OMIM: 608122) gamma-parvin [Homo sapiens] (331 aa) initn: 2133 init1: 2133 opt: 2133 Z-score: 2434.5 bits: 458.8 E(85289): 7.3e-129 Smith-Waterman score: 2133; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 250 260 270 280 290 300 310 320 330 pF1KE0 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN ::::::::::::::::::::::::::::::: NP_071 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 310 320 330 >>XP_011528604 (OMIM: 608122) PREDICTED: gamma-parvin is (398 aa) initn: 2133 init1: 2133 opt: 2133 Z-score: 2433.2 bits: 458.8 E(85289): 8.6e-129 Smith-Waterman score: 2133; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:68-398) 10 20 30 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKK :::::::::::::::::::::::::::::: XP_011 VGDGTLGTPNFCWDHKEKRAAESQLQAWEAMEPEFLYDLLQLPKGVEPPAEEELSKGGKK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 KYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKL 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 EAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRF 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 QPDLSLPTNVQVEVITIESTKSGLKSEKLVEQLTEYSTDKDEPPKDVFDELFKLAPEKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPDLSLPTNVQVEVITIESTKSGLKSEKLVEQLTEYSTDKDEPPKDVFDELFKLAPEKVN 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE0 AVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAE 280 290 300 310 320 330 280 290 300 310 320 330 pF1KE0 MLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAP 340 350 360 370 380 390 pF1KE0 N : XP_011 N >>XP_016884396 (OMIM: 608122) PREDICTED: gamma-parvin is (317 aa) initn: 1809 init1: 1809 opt: 1816 Z-score: 2073.8 bits: 392.0 E(85289): 9e-109 Smith-Waterman score: 1816; 94.8% identity (96.1% similar) in 305 aa overlap (27-331:16-317) 10 20 30 40 50 60 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP :: . : .. .: :: :::::::::::: XP_016 MGRSWQARGRHSEPGGGPGEKSPSPQKLSPW--SLQ-VLMEWINATLLP 10 20 30 40 70 80 90 100 110 120 pF1KE0 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 230 240 250 260 270 280 310 320 330 pF1KE0 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN ::::::::::::::::::::::::::::::: XP_016 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 290 300 310 >>XP_016884397 (OMIM: 608122) PREDICTED: gamma-parvin is (317 aa) initn: 1809 init1: 1809 opt: 1816 Z-score: 2073.8 bits: 392.0 E(85289): 9e-109 Smith-Waterman score: 1816; 94.8% identity (96.1% similar) in 305 aa overlap (27-331:16-317) 10 20 30 40 50 60 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP :: . : .. .: :: :::::::::::: XP_016 MGRSWQARGRHSEPGGGPGEKSPSPQKLSPW--SLQ-VLMEWINATLLP 10 20 30 40 70 80 90 100 110 120 pF1KE0 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 230 240 250 260 270 280 310 320 330 pF1KE0 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN ::::::::::::::::::::::::::::::: XP_016 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 290 300 310 >>XP_005261653 (OMIM: 608121) PREDICTED: beta-parvin iso (312 aa) initn: 862 init1: 465 opt: 863 Z-score: 988.6 bits: 191.2 E(85289): 2.5e-48 Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (19-316:10-308) 10 20 30 40 50 60 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP : . .: .. .. .. :::..::::.:: :::..::: .:. XP_005 MSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVE 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: .:::::. :. . XP_005 ERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:..... .. :.: .. XP_005 GWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHIS 120 130 140 150 160 170 190 200 210 220 230 pF1KE0 EQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQ :.:: :. . : .:.:: :: ::.:...::.....:::..:..:.: : .:.:: XP_005 EELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQ 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 FADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDI ::::: :.::.: :: .:. :..:::::.: . .:::..:.::. : :: . . :::. XP_005 FADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDV 230 240 250 260 270 280 300 310 320 330 pF1KE0 VNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN :: : ::::::::.:: :. XP_005 VNLDLKSTLRVLYNLFTKYKNVE 290 300 310 >>NP_001230314 (OMIM: 608121) beta-parvin isoform c [Hom (327 aa) initn: 862 init1: 465 opt: 863 Z-score: 988.3 bits: 191.2 E(85289): 2.6e-48 Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (19-316:25-323) 10 20 30 40 50 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWI : . .: .. .. .. :::..::::.:: :::..:: NP_001 MSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 NATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVN : .:. :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: .:::::. NP_001 NDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 RSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGL :. . : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:..... .. : NP_001 DLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 KSEKLVEQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSV .: .. :.:: :. . : .:.:: :: ::.:...::.....:::..:..:.: : NP_001 HSSHISEELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEV 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 QNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCP .:.::::::: :.::.: :: .:. :..:::::.: . .:::..:.::. : :: . NP_001 TELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPK 240 250 260 270 280 290 300 310 320 330 pF1KE0 VSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN . :::.:: : ::::::::.:: :. NP_001 ARPEDVVNLDLKSTLRVLYNLFTKYKNVE 300 310 320 >>NP_037459 (OMIM: 608121) beta-parvin isoform b [Homo s (364 aa) initn: 862 init1: 465 opt: 863 Z-score: 987.5 bits: 191.2 E(85289): 2.9e-48 Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (19-316:62-360) 10 20 30 40 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQK : . .: .. .. .. :::..::::.:: : NP_037 KRRAREVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVK 40 50 60 70 80 90 50 60 70 80 90 100 pF1KE0 VLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTV ::..::: .:. :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: . NP_037 VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQT 100 110 120 130 140 150 110 120 130 140 150 160 pF1KE0 VLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIE :::::. :. . : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:.... NP_037 VLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVR 160 170 180 190 200 210 170 180 190 200 210 220 pF1KE0 STKSGLKSEKLVEQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLD . .. :.: .. :.:: :. . : .:.:: :: ::.:...::.....:::..:. NP_037 KREGLLHSSHISEELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLN 220 230 240 250 260 230 240 250 260 270 280 pF1KE0 RLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDE .:.: : .:.::::::: :.::.: :: .:. :..:::::.: . .:::..:.::. : NP_037 KLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDG 270 280 290 300 310 320 290 300 310 320 330 pF1KE0 GLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN :: . . :::.:: : ::::::::.:: :. NP_037 GLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE 330 340 350 360 >>NP_001003828 (OMIM: 608121) beta-parvin isoform a [Hom (397 aa) initn: 862 init1: 465 opt: 863 Z-score: 987.0 bits: 191.2 E(85289): 3.1e-48 Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (19-316:95-393) 10 20 30 40 pF1KE0 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQK : . .: .. .. .. :::..::::.:: : NP_001 EYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVK 70 80 90 100 110 120 50 60 70 80 90 100 pF1KE0 VLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTV ::..::: .:. :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: . NP_001 VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQT 130 140 150 160 170 180 110 120 130 140 150 160 pF1KE0 VLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIE :::::. :. . : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:.... NP_001 VLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVR 190 200 210 220 230 240 170 180 190 200 210 220 pF1KE0 STKSGLKSEKLVEQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLD . .. :.: .. :.:: :. . : .:.:: :: ::.:...::.....:::..:. NP_001 KREGLLHSSHISEELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLN 250 260 270 280 290 300 230 240 250 260 270 280 pF1KE0 RLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDE .:.: : .:.::::::: :.::.: :: .:. :..:::::.: . .:::..:.::. : NP_001 KLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDG 310 320 330 340 350 360 290 300 310 320 330 pF1KE0 GLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN :: . . :::.:: : ::::::::.:: :. NP_001 GLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE 370 380 390 331 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:00:50 2016 done: Thu Nov 3 03:00:51 2016 Total Scan time: 6.140 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]