FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0516, 307 aa 1>>>pF1KE0516 307 - 307 aa - 307 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8835+/-0.00092; mu= 12.0972+/- 0.055 mean_var=60.0718+/-12.197, 0's: 0 Z-trim(103.7): 13 B-trim: 0 in 0/51 Lambda= 0.165478 statistics sampled from 7530 (7534) to 7530 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.231), width: 16 Scan time: 2.070 The best scores are: opt bits E(32554) CCDS46683.1 HORMAD2 gene_id:150280|Hs108|chr22 ( 307) 2031 493.4 9.1e-140 CCDS967.1 HORMAD1 gene_id:84072|Hs108|chr1 ( 394) 903 224.1 1.3e-58 CCDS55633.1 HORMAD1 gene_id:84072|Hs108|chr1 ( 387) 502 128.4 8.7e-30 >>CCDS46683.1 HORMAD2 gene_id:150280|Hs108|chr22 (307 aa) initn: 2031 init1: 2031 opt: 2031 Z-score: 2622.8 bits: 493.4 E(32554): 9.1e-140 Smith-Waterman score: 2031; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KE0 MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQQSSECSRKKRKVSEPVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQQSSECSRKKRKVSEPVK 250 260 270 280 290 300 pF1KE0 VFIPNRK ::::::: CCDS46 VFIPNRK >>CCDS967.1 HORMAD1 gene_id:84072|Hs108|chr1 (394 aa) initn: 937 init1: 546 opt: 903 Z-score: 1165.5 bits: 224.1 E(32554): 1.3e-58 Smith-Waterman score: 903; 48.8% identity (76.4% similar) in 301 aa overlap (1-298:1-292) 10 20 30 40 50 60 pF1KE0 MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE ::::::.. : .: :::..:..::.:: .::.:.:.:.::::::::.::: .:: CCDS96 MATAQLQR--TPMSA---LVFPNKISTEHQSLVLVKRLLAVSVSCITYLRGIFPECAYGT 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY :.:::: .:::::::.:::: ....:. ::.:::.:.::::.::..::.: . ..: : CCDS96 RYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYLRMVVLAVYTNPEDPQTISECY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL :::::::..: ::: :...:. ::. . : ::::.:::::.:::::.: ::::.: : CCDS96 QFKFKYTNNGPLMDFISKNQSN--ESSMLSTDTKKASILLIRKIYILMQNLGPLPNDVCL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK :::: ::. ::: :::: :::.: . . ..:. ::. ..:: ::: :: .:::: :: . CCDS96 TMKLFYYDEVTPPDYQPPGFKDG-DCEGVIFEGEPMYLNVGEVSTPFHIFKVKVTTERER 180 190 200 210 220 230 250 260 270 280 290 pF1KE0 VIDLENNLFRENSTTEIAHQGL-DCDEEEECNDHIQR--MNFVCSQQSSECSRKKRKVSE . ....... .. .. : : : :.: ..: ... ... .: . . .. : CCDS96 MENIDSTILSPKQIKTPFQKILRDKDVEDE-QEHYTSDDLDIETKMEEQEKNPASSELEE 240 250 260 270 280 290 300 pF1KE0 PVKVFIPNRK : CCDS96 PSLVCEEDEIMRSKESPDLSISHSQVEQLVNKTSELDMSESKTRSGKVFQNKMANGNQPV 300 310 320 330 340 350 >>CCDS55633.1 HORMAD1 gene_id:84072|Hs108|chr1 (387 aa) initn: 894 init1: 393 opt: 502 Z-score: 648.3 bits: 128.4 E(32554): 8.7e-30 Smith-Waterman score: 850; 47.2% identity (74.1% similar) in 301 aa overlap (1-298:1-285) 10 20 30 40 50 60 pF1KE0 MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE ::::::.. : .: :::..:..::.:: .::.:.:.:.::::::::.::: .:: CCDS55 MATAQLQR--TPMSA---LVFPNKISTEHQSLVLVKRLLAVSVSCITYLRGIFPECAYGT 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY :.:::: .:::::::.:::: ....:. ::.:::.:.:. ::.: . ..: : CCDS55 RYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYV-------YTNPEDPQTISECY 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL :::::::..: ::: :...:. ::. . : ::::.:::::.:::::.: ::::.: : CCDS55 QFKFKYTNNGPLMDFISKNQSN--ESSMLSTDTKKASILLIRKIYILMQNLGPLPNDVCL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK :::: ::. ::: :::: :::.: . . ..:. ::. ..:: ::: :: .:::: :: . CCDS55 TMKLFYYDEVTPPDYQPPGFKDG-DCEGVIFEGEPMYLNVGEVSTPFHIFKVKVTTERER 170 180 190 200 210 220 250 260 270 280 290 pF1KE0 VIDLENNLFRENSTTEIAHQGL-DCDEEEECNDHIQR--MNFVCSQQSSECSRKKRKVSE . ....... .. .. : : : :.: ..: ... ... .: . . .. : CCDS55 MENIDSTILSPKQIKTPFQKILRDKDVEDE-QEHYTSDDLDIETKMEEQEKNPASSELEE 230 240 250 260 270 280 300 pF1KE0 PVKVFIPNRK : CCDS55 PSLVCEEDEIMRSKESPDLSISHSQVEQLVNKTSELDMSESKTRSGKVFQNKMANGNQPV 290 300 310 320 330 340 307 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:34:22 2016 done: Thu Nov 3 02:34:22 2016 Total Scan time: 2.070 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]