FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0517, 309 aa 1>>>pF1KE0517 309 - 309 aa - 309 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2958+/-0.000303; mu= -0.0872+/- 0.019 mean_var=271.1693+/-54.827, 0's: 0 Z-trim(125.1): 17 B-trim: 21 in 1/61 Lambda= 0.077885 statistics sampled from 48136 (48157) to 48136 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.565), width: 16 Scan time: 8.560 The best scores are: opt bits E(85289) NP_001008695 (OMIM: 609518) THAP domain-containing ( 309) 2149 253.7 3.5e-67 NP_085050 (OMIM: 609518) THAP domain-containing pr ( 309) 2149 253.7 3.5e-67 NP_078948 (OMIM: 612537) DNA transposase THAP9 iso ( 903) 292 45.5 0.00049 >>NP_001008695 (OMIM: 609518) THAP domain-containing pro (309 aa) initn: 2149 init1: 2149 opt: 2149 Z-score: 1327.2 bits: 253.7 E(85289): 3.5e-67 Smith-Waterman score: 2149; 99.7% identity (99.7% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KE0 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPPEVSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_001 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF 250 260 270 280 290 300 pF1KE0 AMQLSSSMA ::::::::: NP_001 AMQLSSSMA >>NP_085050 (OMIM: 609518) THAP domain-containing protei (309 aa) initn: 2149 init1: 2149 opt: 2149 Z-score: 1327.2 bits: 253.7 E(85289): 3.5e-67 Smith-Waterman score: 2149; 99.7% identity (99.7% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KE0 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPPEVSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_085 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF 250 260 270 280 290 300 pF1KE0 AMQLSSSMA ::::::::: NP_085 AMQLSSSMA >>NP_078948 (OMIM: 612537) DNA transposase THAP9 isoform (903 aa) initn: 211 init1: 123 opt: 292 Z-score: 193.4 bits: 45.5 E(85289): 0.00049 Smith-Waterman score: 292; 43.1% identity (71.6% similar) in 109 aa overlap (1-109:1-103) 10 20 30 40 50 60 pF1KE0 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY : : :::.:: :::: .:.::.:::..: :. .:. :. .:.:: .. .: :. NP_078 MTRSCSAVGCSTRDTVLSRERGLSFHQFPT-DTIQRSKWIRAVNRVDPRSKKIWIPGPGA 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPPEVSRL : .:::::.:. :: :: ..::.::::.. :. :. . .. ::.. NP_078 I-LCSKHFQESDFESYGIR--RKLKKGAVPSV--SLYKIPQGVHLKGKARQKILKQPLPD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG NP_078 NSQEVATEDHNYSLKTPLTIGAEKLAEVQQMLQVSKKRLISVKNYRMIKKRKGLRLIDAL 120 130 140 150 160 170 309 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:21:31 2016 done: Thu Nov 3 02:21:32 2016 Total Scan time: 8.560 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]