FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0519, 192 aa 1>>>pF1KE0519 192 - 192 aa - 192 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8231+/-0.000624; mu= 14.9219+/- 0.038 mean_var=159.5092+/-32.916, 0's: 0 Z-trim(118.0): 61 B-trim: 4 in 1/52 Lambda= 0.101550 statistics sampled from 18768 (18838) to 18768 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.866), E-opt: 0.2 (0.579), width: 16 Scan time: 2.220 The best scores are: opt bits E(32554) CCDS13890.1 RNF185 gene_id:91445|Hs108|chr22 ( 192) 1379 212.2 1.6e-55 CCDS4745.1 RNF5 gene_id:6048|Hs108|chr6 ( 180) 788 125.5 1.8e-29 CCDS46689.1 RNF185 gene_id:91445|Hs108|chr22 ( 136) 501 83.3 7.1e-17 >>CCDS13890.1 RNF185 gene_id:91445|Hs108|chr22 (192 aa) initn: 1379 init1: 1379 opt: 1379 Z-score: 1110.1 bits: 212.2 E(32554): 1.6e-55 Smith-Waterman score: 1379; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192) 10 20 30 40 50 60 pF1KE0 MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLF 130 140 150 160 170 180 190 pF1KE0 VALVIMFWLLIA :::::::::::: CCDS13 VALVIMFWLLIA 190 >>CCDS4745.1 RNF5 gene_id:6048|Hs108|chr6 (180 aa) initn: 729 init1: 616 opt: 788 Z-score: 642.4 bits: 125.5 E(32554): 1.8e-29 Smith-Waterman score: 788; 60.9% identity (77.7% similar) in 184 aa overlap (8-190:2-178) 10 20 30 40 50 60 pF1KE0 MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW :.: :. ::: : . : :: .::::::::.::..::.:.::::.:: CCDS47 MAAAEEED---GGPEGPNR---ERGGAGATFECNICLETAREAVVSVCGHLYCW 10 20 30 40 70 80 90 100 110 120 pF1KE0 PCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENR :::::::::::.:: ::::::::::.::.::::::: :::: ::::::::::: ::.: CCDS47 PCLHQWLETRPERQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESR 50 60 70 80 90 100 130 140 150 160 170 pF1KE0 GGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDG-RPPPAVPGTPQYVDEQFLSRLFL :::: :: :::..:::.::::::.:.:.:: .. : .: . .. . ::: CCDS47 GGFQPFG-DTGGFHFSFGVGAFPFGFFTTVFNAHEPFRRGTGVDLGQGHPASSWQDSLFL 110 120 130 140 150 160 180 190 pF1KE0 FVALVIMFWLLIA :.:. ..:::: CCDS47 FLAIFFFFWLLSI 170 180 >>CCDS46689.1 RNF185 gene_id:91445|Hs108|chr22 (136 aa) initn: 950 init1: 500 opt: 501 Z-score: 416.5 bits: 83.3 E(32554): 7.1e-17 Smith-Waterman score: 842; 70.8% identity (70.8% similar) in 192 aa overlap (1-192:1-136) 10 20 30 40 50 60 pF1KE0 MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENR ::::: CCDS46 PCLHQ------------------------------------------------------- 130 140 150 160 170 180 pF1KE0 GGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 -GFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLF 70 80 90 100 110 120 190 pF1KE0 VALVIMFWLLIA :::::::::::: CCDS46 VALVIMFWLLIA 130 192 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:11:50 2016 done: Thu Nov 3 02:11:51 2016 Total Scan time: 2.220 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]