FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0519, 192 aa
  1>>>pF1KE0519 192 - 192 aa - 192 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7532+/-0.000256; mu= 15.0589+/- 0.016
 mean_var=159.9157+/-32.823, 0's: 0 Z-trim(125.3): 113  B-trim: 19 in 1/55
 Lambda= 0.101421
 statistics sampled from 48614 (48792) to 48614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.864), E-opt: 0.2 (0.572), width:  16
 Scan time:  5.090

The best scores are:                                      opt bits E(85289)
NP_008844 (OMIM: 602677) E3 ubiquitin-protein liga ( 180)  788 125.4 5.1e-29


>>NP_008844 (OMIM: 602677) E3 ubiquitin-protein ligase R  (180 aa)
 initn: 729 init1: 616 opt: 788  Z-score: 642.0  bits: 125.4 E(85289): 5.1e-29
Smith-Waterman score: 788; 60.9% identity (77.7% similar) in 184 aa overlap (8-190:2-178)

               10        20        30        40        50        60
pF1KE0 MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCW
              :.:  :.   ::: : .    : ::  .::::::::.::..::.:.::::.::
NP_008       MAAAEEED---GGPEGPNR---ERGGAGATFECNICLETAREAVVSVCGHLYCW
                        10           20        30        40        

               70        80        90       100       110       120
pF1KE0 PCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENR
       :::::::::::.:: ::::::::::.::.:::::::   :::: ::::::::::: ::.:
NP_008 PCLHQWLETRPERQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESR
       50        60        70        80        90       100        

              130       140       150        160       170         
pF1KE0 GGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDG-RPPPAVPGTPQYVDEQFLSRLFL
       :::: ::   :::..:::.::::::.:.:.:: ..  :   .:     .   .. . :::
NP_008 GGFQPFG-DTGGFHFSFGVGAFPFGFFTTVFNAHEPFRRGTGVDLGQGHPASSWQDSLFL
      110        120       130       140       150       160       

     180       190  
pF1KE0 FVALVIMFWLLIA
       :.:. ..::::  
NP_008 FLAIFFFFWLLSI
       170       180




192 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 02:11:51 2016 done: Thu Nov  3 02:11:52 2016
 Total Scan time:  5.090 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]