FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0521, 276 aa 1>>>pF1KE0521 276 - 276 aa - 276 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4522+/-0.000796; mu= 13.7305+/- 0.048 mean_var=61.2129+/-12.210, 0's: 0 Z-trim(107.0): 17 B-trim: 0 in 0/50 Lambda= 0.163928 statistics sampled from 9276 (9286) to 9276 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.285), width: 16 Scan time: 2.330 The best scores are: opt bits E(32554) CCDS13772.1 TANGO2 gene_id:128989|Hs108|chr22 ( 276) 1859 448.0 3.4e-126 CCDS63405.1 TANGO2 gene_id:128989|Hs108|chr22 ( 317) 1734 418.5 3e-117 CCDS63407.1 TANGO2 gene_id:128989|Hs108|chr22 ( 178) 1012 247.6 4.6e-66 CCDS63406.1 TANGO2 gene_id:128989|Hs108|chr22 ( 198) 892 219.3 1.8e-57 CCDS74821.1 TANGO2 gene_id:128989|Hs108|chr22 ( 201) 847 208.6 2.8e-54 CCDS63404.1 TANGO2 gene_id:128989|Hs108|chr22 ( 214) 842 207.5 6.8e-54 CCDS74822.1 TANGO2 gene_id:128989|Hs108|chr22 ( 107) 618 154.4 3.2e-38 >>CCDS13772.1 TANGO2 gene_id:128989|Hs108|chr22 (276 aa) initn: 1859 init1: 1859 opt: 1859 Z-score: 2379.1 bits: 448.0 E(32554): 3.4e-126 Smith-Waterman score: 1859; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276) 10 20 30 40 50 60 pF1KE0 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGKQLFLEAVER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGKQLFLEAVER 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNT 190 200 210 220 230 240 250 260 270 pF1KE0 IILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS :::::::::::::::::::::::::::::::::::: CCDS13 IILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS 250 260 270 >>CCDS63405.1 TANGO2 gene_id:128989|Hs108|chr22 (317 aa) initn: 1734 init1: 1734 opt: 1734 Z-score: 2218.4 bits: 418.5 E(32554): 3e-117 Smith-Waterman score: 1734; 98.1% identity (100.0% similar) in 263 aa overlap (14-276:55-317) 10 20 30 40 pF1KE0 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNN .....::::::::::::::::::::::::: CCDS63 PGQGHSVWDAVRMPLGAGTPVNVQRREDSATEGSHRLILAANRDEFYSRPSKLADFWGNN 30 40 50 60 70 80 50 60 70 80 90 100 pF1KE0 NEILSGLDMEEGKEGGTWLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NEILSGLDMEEGKEGGTWLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSL 90 100 110 120 130 140 110 120 130 140 150 160 pF1KE0 SYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETP 150 160 170 180 190 200 170 180 190 200 210 220 pF1KE0 WRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 WRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSK 210 220 230 240 250 260 230 240 250 260 270 pF1KE0 YAAVCVRCPGYGTRTNTIILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YAAVCVRCPGYGTRTNTIILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS 270 280 290 300 310 >>CCDS63407.1 TANGO2 gene_id:128989|Hs108|chr22 (178 aa) initn: 1028 init1: 1012 opt: 1012 Z-score: 1299.6 bits: 247.6 E(32554): 4.6e-66 Smith-Waterman score: 1012; 100.0% identity (100.0% similar) in 150 aa overlap (127-276:29-178) 100 110 120 130 140 150 pF1KE0 TTDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLS :::::::::::::::::::::::::::::: CCDS63 MAGHQHTWQAGSTHQLPAAAAGLAGPRASTAKGDVICYYGNRGEPDPIVLTPGTYGLS 10 20 30 40 50 160 170 180 190 200 210 pF1KE0 NALLETPWRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NALLETPWRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEY 60 70 80 90 100 110 220 230 240 250 260 270 pF1KE0 VQPMLSKYAAVCVRCPGYGTRTNTIILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VQPMLSKYAAVCVRCPGYGTRTNTIILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS 120 130 140 150 160 170 >>CCDS63406.1 TANGO2 gene_id:128989|Hs108|chr22 (198 aa) initn: 892 init1: 892 opt: 892 Z-score: 1145.5 bits: 219.3 E(32554): 1.8e-57 Smith-Waterman score: 892; 96.4% identity (100.0% similar) in 137 aa overlap (14-150:55-191) 10 20 30 40 pF1KE0 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNN .....::::::::::::::::::::::::: CCDS63 PGQGHSVWDAVRMPLGAGTPVNVQRREDSATEGSHRLILAANRDEFYSRPSKLADFWGNN 30 40 50 60 70 80 50 60 70 80 90 100 pF1KE0 NEILSGLDMEEGKEGGTWLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NEILSGLDMEEGKEGGTWLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSL 90 100 110 120 130 140 110 120 130 140 150 160 pF1KE0 SYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETP ::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIVLTPEPTLSSW 150 160 170 180 190 170 180 190 200 210 220 pF1KE0 WRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSK >>CCDS74821.1 TANGO2 gene_id:128989|Hs108|chr22 (201 aa) initn: 1341 init1: 847 opt: 847 Z-score: 1087.9 bits: 208.6 E(32554): 2.8e-54 Smith-Waterman score: 1194; 72.5% identity (72.5% similar) in 276 aa overlap (1-276:1-201) 10 20 30 40 50 60 pF1KE0 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 WLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGKQLFLEAVER :::::: CCDS74 LIAADLR----------------------------------------------------- 190 200 210 220 230 240 pF1KE0 SQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNT :::::::::::::::::::::::::::::::::::::: CCDS74 ----------------------QLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNT 130 140 150 160 250 260 270 pF1KE0 IILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS :::::::::::::::::::::::::::::::::::: CCDS74 IILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS 170 180 190 200 >>CCDS63404.1 TANGO2 gene_id:128989|Hs108|chr22 (214 aa) initn: 842 init1: 842 opt: 842 Z-score: 1081.0 bits: 207.5 E(32554): 6.8e-54 Smith-Waterman score: 1315; 77.5% identity (77.5% similar) in 276 aa overlap (1-276:1-214) 10 20 30 40 50 60 pF1KE0 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFN ::::::::::::::::::::::::::::: CCDS63 WLGISTRGKLAALTNYLQPQLDWQARGRG------------------------------- 70 80 130 140 150 160 170 180 pF1KE0 LIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGKQLFLEAVER ::::::::::::::::::::::::::::: CCDS63 -------------------------------TYGLSNALLETPWRKLCFGKQLFLEAVER 90 100 110 190 200 210 220 230 240 pF1KE0 SQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNT 120 130 140 150 160 170 250 260 270 pF1KE0 IILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS :::::::::::::::::::::::::::::::::::: CCDS63 IILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQS 180 190 200 210 >>CCDS74822.1 TANGO2 gene_id:128989|Hs108|chr22 (107 aa) initn: 615 init1: 615 opt: 618 Z-score: 799.6 bits: 154.4 E(32554): 3.2e-38 Smith-Waterman score: 618; 91.2% identity (92.2% similar) in 102 aa overlap (1-102:1-102) 10 20 30 40 50 60 pF1KE0 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFN ::::::::::::::::::::::::::::: :. : : : CCDS74 WLGISTRGKLAALTNYLQPQLDWQARGRGSCQTRPSRTRVGSTCSPC 70 80 90 100 130 140 150 160 170 180 pF1KE0 LIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGKQLFLEAVER 276 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:02:29 2016 done: Thu Nov 3 02:02:29 2016 Total Scan time: 2.330 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]