FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0524, 239 aa 1>>>pF1KE0524 239 - 239 aa - 239 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1397+/-0.000799; mu= 15.8978+/- 0.048 mean_var=77.2567+/-15.998, 0's: 0 Z-trim(108.9): 18 B-trim: 82 in 1/49 Lambda= 0.145917 statistics sampled from 10522 (10532) to 10522 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.324), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS46672.1 DERL3 gene_id:91319|Hs108|chr22 ( 239) 1609 347.7 4e-96 CCDS33615.1 DERL3 gene_id:91319|Hs108|chr22 ( 235) 1402 304.1 5.1e-83 CCDS42986.1 DERL3 gene_id:91319|Hs108|chr22 ( 205) 1386 300.7 4.8e-82 CCDS11073.1 DERL2 gene_id:51009|Hs108|chr17 ( 239) 1158 252.8 1.5e-67 CCDS6337.1 DERL1 gene_id:79139|Hs108|chr8 ( 251) 493 112.8 2.2e-25 CCDS47915.1 DERL1 gene_id:79139|Hs108|chr8 ( 231) 415 96.3 1.8e-20 CCDS76927.1 DERL2 gene_id:51009|Hs108|chr17 ( 74) 280 67.5 2.7e-12 >>CCDS46672.1 DERL3 gene_id:91319|Hs108|chr22 (239 aa) initn: 1609 init1: 1609 opt: 1609 Z-score: 1839.3 bits: 347.7 E(32554): 4e-96 Smith-Waterman score: 1609; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS 190 200 210 220 230 >>CCDS33615.1 DERL3 gene_id:91319|Hs108|chr22 (235 aa) initn: 1453 init1: 1389 opt: 1402 Z-score: 1603.9 bits: 304.1 E(32554): 5.1e-83 Smith-Waterman score: 1402; 92.6% identity (94.3% similar) in 229 aa overlap (1-229:1-228) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS ::::::::::::::::::::::::: : . ::: . . . : :: CCDS33 IYYFLEDVFPNQPGGKRLLQTPGFLKLLLD-APAEDPNYLPLPEEQPGPHLPPPQQ 190 200 210 220 230 >>CCDS42986.1 DERL3 gene_id:91319|Hs108|chr22 (205 aa) initn: 1386 init1: 1386 opt: 1386 Z-score: 1586.5 bits: 300.7 E(32554): 4.8e-82 Smith-Waterman score: 1386; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS ::::::::::::::::::::::::: CCDS42 IYYFLEDVFPNQPGGKRLLQTPGFL 190 200 >>CCDS11073.1 DERL2 gene_id:51009|Hs108|chr17 (239 aa) initn: 1158 init1: 1158 opt: 1158 Z-score: 1326.2 bits: 252.8 E(32554): 1.5e-67 Smith-Waterman score: 1158; 79.0% identity (95.1% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN ::.:.: :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.:: CCDS11 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: :: CCDS11 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH :::. :::::::::.: ::.::::::.::::::::.::::::::::::.:::::::::: CCDS11 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS ::.:::::::::::: :.:.::..: CCDS11 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG 190 200 210 220 230 >>CCDS6337.1 DERL1 gene_id:79139|Hs108|chr8 (251 aa) initn: 479 init1: 365 opt: 493 Z-score: 569.3 bits: 112.8 E(32554): 2.2e-25 Smith-Waterman score: 495; 33.8% identity (64.6% similar) in 237 aa overlap (10-234:8-244) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN : ..::.:: . :: : . . .: :.:: :.. :. . .::.:: .: CCDS63 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITA 10 20 30 40 50 70 80 90 100 110 pF1KE0 FLFF--GP-LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSL ..: :: :: .. :. :...: :: :.: :: ::..::.::. . ... :: .. CCDS63 TFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 FFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIA .: :. ..:::.. . . :.:. :.: .:::...::. ..:.:.. .:.: CCDS63 QLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNL 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 VGHIYYFLEDVFPNQPGGKRLLQTPGFL---------GLQSSKAPAGSSLTIWTQQSQGG :::.:.:: .: . ::. .:.:: :: :... .: .: :.. :: CCDS63 VGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGG 180 190 200 210 220 230 230 pF1KE0 PGTAGELAAPS . :. CCDS63 RHNWGQGFRLGDQ 240 250 >>CCDS47915.1 DERL1 gene_id:79139|Hs108|chr8 (231 aa) initn: 395 init1: 281 opt: 415 Z-score: 481.0 bits: 96.3 E(32554): 1.8e-20 Smith-Waterman score: 415; 31.8% identity (61.8% similar) in 217 aa overlap (10-223:8-224) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN : ..::.:: . :: : . . .: :.:: :.. :. . .::.:: .: CCDS47 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITA 10 20 30 40 50 70 80 90 100 110 pF1KE0 FLFF--GP-LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSL ..: :: :: .. :. :...: :: :.: :: ::..::.::. . ... :: .. CCDS47 TFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 FFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIA .: :. ..:::.. . . :.:. :.: .:::...::. ..:.: .:: : CCDS47 QLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VGHIYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAA :: .:.. :: . .: ... .:.. : : CCDS47 FLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ 180 190 200 210 220 230 pF1KE0 PS >>CCDS76927.1 DERL2 gene_id:51009|Hs108|chr17 (74 aa) initn: 277 init1: 277 opt: 280 Z-score: 334.1 bits: 67.5 E(32554): 2.7e-12 Smith-Waterman score: 280; 62.3% identity (85.5% similar) in 69 aa overlap (1-69:1-68) 10 20 30 40 50 60 pF1KE0 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN ::.:.: :.::.: :.::::.:::::::::::::..::::::::.:.:..::: .: : CCDS76 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQVLQLDT- 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL ..: . : CCDS76 YIFSWKMYFPINLVE 60 70 239 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:56:09 2016 done: Thu Nov 3 01:56:10 2016 Total Scan time: 2.230 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]