Result of FASTA (omim) for
pF1KE0527
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0527, 244 aa
1>>>pF1KE0527 244 - 244 aa - 244 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8871+/-0.000355; mu= 16.7627+/- 0.022
mean_var=66.1736+/-13.729, 0's: 0 Z-trim(114.1): 27 B-trim: 0 in 0/52
Lambda= 0.157664
statistics sampled from 23773 (23797) to 23773 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.279), width: 16
Scan time: 5.710
The best scores are: opt bits E(85289)
NP_000845 (OMIM: 600437) glutathione S-transferase ( 244) 1622 377.6 1.1e-104
NP_001289599 (OMIM: 600437) glutathione S-transfer ( 230) 1090 256.5 2.9e-68
NP_000844 (OMIM: 600436) glutathione S-transferase ( 240) 834 198.3 1e-50
NP_001280742 (OMIM: 600436) glutathione S-transfer ( 105) 337 85.0 5.7e-17
NP_001280736 (OMIM: 600436) glutathione S-transfer ( 226) 323 82.1 9.4e-16
NP_001280738 (OMIM: 600436) glutathione S-transfer ( 122) 315 80.0 2.1e-15
NP_001280737 (OMIM: 600436) glutathione S-transfer ( 122) 315 80.0 2.1e-15
NP_001280741 (OMIM: 600436) glutathione S-transfer ( 122) 315 80.0 2.1e-15
NP_001280739 (OMIM: 600436) glutathione S-transfer ( 122) 315 80.0 2.1e-15
NP_001280740 (OMIM: 600436) glutathione S-transfer ( 122) 315 80.0 2.1e-15
NP_001280743 (OMIM: 600436) glutathione S-transfer ( 72) 198 53.2 1.4e-07
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 151 42.9 0.00054
>>NP_000845 (OMIM: 600437) glutathione S-transferase the (244 aa)
initn: 1622 init1: 1622 opt: 1622 Z-score: 2000.2 bits: 377.6 E(85289): 1.1e-104
Smith-Waterman score: 1622; 99.6% identity (100.0% similar) in 244 aa overlap (1-244:1-244)
10 20 30 40 50 60
pF1KE0 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALG
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 YELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRI
190 200 210 220 230 240
pF1KE0 ARIP
::::
NP_000 ARIP
>>NP_001289599 (OMIM: 600437) glutathione S-transferase (230 aa)
initn: 1090 init1: 1090 opt: 1090 Z-score: 1346.6 bits: 256.5 E(85289): 2.9e-68
Smith-Waterman score: 1503; 93.9% identity (94.3% similar) in 244 aa overlap (1-244:1-230)
10 20 30 40 50 60
pF1KE0 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALG
::::::::.:::::::::::::::::::::::::::::::: :::::
NP_001 PLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQ--------------PVALG
130 140 150 160
190 200 210 220 230 240
pF1KE0 YELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRI
170 180 190 200 210 220
pF1KE0 ARIP
::::
NP_001 ARIP
230
>>NP_000844 (OMIM: 600436) glutathione S-transferase the (240 aa)
initn: 819 init1: 532 opt: 834 Z-score: 1031.7 bits: 198.3 E(85289): 1e-50
Smith-Waterman score: 834; 54.2% identity (74.8% similar) in 238 aa overlap (1-237:1-232)
10 20 30 40 50 60
pF1KE0 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
:::::.:::.::: :::::::::: ::.::: :::.:::: : : :.: : :.:.::::
NP_000 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
:: :::: :::.::. ::..::.:::.:::::::: :::.:. .: . :: .:.
NP_000 DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 PL-IGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVAL
:. .: : . . . . .: .:: :::::: .. ::.: ...::::.:. :::.::.
NP_000 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 GYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLR
: ..:::::.::.:: :::: .: .: :::: .::. : .: .: : ..
NP_000 GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKA------KDFPPADPTIKQKLMPW
190 200 210 220 230
240
pF1KE0 IARIP
NP_000 VLAMIR
240
>>NP_001280742 (OMIM: 600436) glutathione S-transferase (105 aa)
initn: 347 init1: 333 opt: 337 Z-score: 425.7 bits: 85.0 E(85289): 5.7e-17
Smith-Waterman score: 337; 68.8% identity (79.2% similar) in 77 aa overlap (1-77:1-77)
10 20 30 40 50 60
pF1KE0 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
:::::.:::.::: :::::::::: ::.::: :::.:::: : : :.: : :.:.::::
NP_001 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
:: :::: .: : :
NP_001 DFTLTESPWVLAAKSSKADPSWPHGGSAWRQQWGRTSSRRPMRSF
70 80 90 100
>>NP_001280736 (OMIM: 600436) glutathione S-transferase (226 aa)
initn: 484 init1: 301 opt: 323 Z-score: 403.8 bits: 82.1 E(85289): 9.4e-16
Smith-Waterman score: 464; 38.5% identity (61.1% similar) in 239 aa overlap (1-237:1-218)
10 20 30 40 50
pF1KE0 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVK-GQHKSKEFLQINSLGKLPTLKD
:::::.:::.::: :::::::::: ::.::: :::.: : . . . ..: . .
NP_001 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKDGVSLCRPGWSAVAGSQLTATSA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 G-DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQV
. ...: :..: . :.. .. : : : : : .:..
NP_001 ARNLVLC-----LLFLLGRSALKRCLCPGEPPQEGASLEGRGLHLD---GEVMFPVF---
70 80 90 100
120 130 140 150 160 170
pF1KE0 LGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVA
.: : . . . . .: .:: :::::: .. ::.: ...::::.:. :::.::.
NP_001 ----LGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 LGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLL
: ..:::::.::.:: :::: .: .: :::: .::. : .: .: : ..
NP_001 AGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKA------KDFPPADPTIKQKLMP
170 180 190 200 210
240
pF1KE0 RIARIP
NP_001 WVLAMIR
220
>>NP_001280738 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 301 init1: 301 opt: 315 Z-score: 397.7 bits: 80.0 E(85289): 2.1e-15
Smith-Waterman score: 315; 43.1% identity (69.0% similar) in 116 aa overlap (122-237:5-114)
100 110 120 130 140 150
pF1KE0 RARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFL
..: : . . . . .: .:: ::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFL
10 20 30
160 170 180 190 200 210
pF1KE0 GDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHS
.. ::.: ...::::.:. :::.::. : ..:::::.::.:: :::: .: .: ::::
NP_001 QNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHE
40 50 60 70 80 90
220 230 240
pF1KE0 IILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
.::. : .: .: : ..
NP_001 VILKA------KDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280737 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 301 init1: 301 opt: 315 Z-score: 397.7 bits: 80.0 E(85289): 2.1e-15
Smith-Waterman score: 315; 43.1% identity (69.0% similar) in 116 aa overlap (122-237:5-114)
100 110 120 130 140 150
pF1KE0 RARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFL
..: : . . . . .: .:: ::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFL
10 20 30
160 170 180 190 200 210
pF1KE0 GDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHS
.. ::.: ...::::.:. :::.::. : ..:::::.::.:: :::: .: .: ::::
NP_001 QNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHE
40 50 60 70 80 90
220 230 240
pF1KE0 IILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
.::. : .: .: : ..
NP_001 VILKA------KDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280741 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 301 init1: 301 opt: 315 Z-score: 397.7 bits: 80.0 E(85289): 2.1e-15
Smith-Waterman score: 315; 43.1% identity (69.0% similar) in 116 aa overlap (122-237:5-114)
100 110 120 130 140 150
pF1KE0 RARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFL
..: : . . . . .: .:: ::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFL
10 20 30
160 170 180 190 200 210
pF1KE0 GDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHS
.. ::.: ...::::.:. :::.::. : ..:::::.::.:: :::: .: .: ::::
NP_001 QNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHE
40 50 60 70 80 90
220 230 240
pF1KE0 IILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
.::. : .: .: : ..
NP_001 VILKA------KDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280739 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 301 init1: 301 opt: 315 Z-score: 397.7 bits: 80.0 E(85289): 2.1e-15
Smith-Waterman score: 315; 43.1% identity (69.0% similar) in 116 aa overlap (122-237:5-114)
100 110 120 130 140 150
pF1KE0 RARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFL
..: : . . . . .: .:: ::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFL
10 20 30
160 170 180 190 200 210
pF1KE0 GDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHS
.. ::.: ...::::.:. :::.::. : ..:::::.::.:: :::: .: .: ::::
NP_001 QNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHE
40 50 60 70 80 90
220 230 240
pF1KE0 IILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
.::. : .: .: : ..
NP_001 VILKA------KDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280740 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 301 init1: 301 opt: 315 Z-score: 397.7 bits: 80.0 E(85289): 2.1e-15
Smith-Waterman score: 315; 43.1% identity (69.0% similar) in 116 aa overlap (122-237:5-114)
100 110 120 130 140 150
pF1KE0 RARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFL
..: : . . . . .: .:: ::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFL
10 20 30
160 170 180 190 200 210
pF1KE0 GDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHS
.. ::.: ...::::.:. :::.::. : ..:::::.::.:: :::: .: .: ::::
NP_001 QNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHE
40 50 60 70 80 90
220 230 240
pF1KE0 IILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
.::. : .: .: : ..
NP_001 VILKA------KDFPPADPTIKQKLMPWVLAMIR
100 110 120
244 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:41:13 2016 done: Thu Nov 3 01:41:14 2016
Total Scan time: 5.710 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]