FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0528, 288 aa 1>>>pF1KE0528 288 - 288 aa - 288 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6554+/-0.000766; mu= 14.6395+/- 0.046 mean_var=76.3895+/-15.109, 0's: 0 Z-trim(109.1): 7 B-trim: 0 in 0/51 Lambda= 0.146743 statistics sampled from 10654 (10658) to 10654 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.327), width: 16 Scan time: 2.650 The best scores are: opt bits E(32554) CCDS13914.1 HMOX1 gene_id:3162|Hs108|chr22 ( 288) 1882 407.3 6.5e-114 CCDS66931.1 HMOX2 gene_id:3163|Hs108|chr16 ( 287) 837 186.1 2.6e-47 CCDS10517.1 HMOX2 gene_id:3163|Hs108|chr16 ( 316) 837 186.1 2.8e-47 CCDS73818.1 HMOX2 gene_id:3163|Hs108|chr16 ( 370) 837 186.2 3.2e-47 >>CCDS13914.1 HMOX1 gene_id:3162|Hs108|chr22 (288 aa) initn: 1882 init1: 1882 opt: 1882 Z-score: 2158.6 bits: 407.3 E(32554): 6.5e-114 Smith-Waterman score: 1882; 100.0% identity (100.0% similar) in 288 aa overlap (1-288:1-288) 10 20 30 40 50 60 pF1KE0 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA 190 200 210 220 230 240 250 260 270 280 pF1KE0 SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM :::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM 250 260 270 280 >>CCDS66931.1 HMOX2 gene_id:3163|Hs108|chr16 (287 aa) initn: 859 init1: 837 opt: 837 Z-score: 963.0 bits: 186.1 E(32554): 2.6e-47 Smith-Waterman score: 837; 56.2% identity (83.2% similar) in 208 aa overlap (12-219:3-210) 10 20 30 40 50 60 pF1KE0 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA :::: :::.:::.: .:::..:...: ::.. .. :::. ..:: : : CCDS66 MADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSA 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE ::::.::::. :.:::.::: ::::: :: .:. ...: :.: . : :.::.:.: CCDS66 LEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ .:..:::::::::::::.:::::::::::.::.:: :::.::: :. : :. .: .::: CCDS66 IGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA :::.:::.:... ...:..:::. :: :.:.:.::.. CCDS66 LYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKG 180 190 200 210 220 230 250 260 270 280 pF1KE0 SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM CCDS66 DMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM 240 250 260 270 280 >>CCDS10517.1 HMOX2 gene_id:3163|Hs108|chr16 (316 aa) initn: 859 init1: 837 opt: 837 Z-score: 962.4 bits: 186.1 E(32554): 2.8e-47 Smith-Waterman score: 837; 56.2% identity (83.2% similar) in 208 aa overlap (12-219:32-239) 10 20 30 40 pF1KE0 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQ :::: :::.:::.: .:::..:...: ::. CCDS10 SAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 VTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRW . .. :::. ..:: : :::::.::::. :.:::.::: ::::: :: .:. ...: : CCDS10 IKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENW 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 QEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSG .: . : :.::.:.: .:..:::::::::::::.:::::::::::.::.:: :::.: CCDS10 EEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 EGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELL :: :. : :. .: .::::::.:::.:... ...:..:::. :: :.:.:.::.. CCDS10 EGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 THDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATV CCDS10 STLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILA 250 260 270 280 290 300 >>CCDS73818.1 HMOX2 gene_id:3163|Hs108|chr16 (370 aa) initn: 859 init1: 837 opt: 837 Z-score: 961.3 bits: 186.2 E(32554): 3.2e-47 Smith-Waterman score: 837; 56.2% identity (83.2% similar) in 208 aa overlap (12-219:86-293) 10 20 30 40 pF1KE0 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQ :::: :::.:::.: .:::..:...: ::. CCDS73 SAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGN 60 70 80 90 100 110 50 60 70 80 90 100 pF1KE0 VTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRW . .. :::. ..:: : :::::.::::. :.:::.::: ::::: :: .:. ...: : CCDS73 IKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENW 120 130 140 150 160 170 110 120 130 140 150 160 pF1KE0 QEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSG .: . : :.::.:.: .:..:::::::::::::.:::::::::::.::.:: :::.: CCDS73 EEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTG 180 190 200 210 220 230 170 180 190 200 210 220 pF1KE0 EGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELL :: :. : :. .: .::::::.:::.:... ...:..:::. :: :.:.:.::.. CCDS73 EGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAG 240 250 260 270 280 290 230 240 250 260 270 280 pF1KE0 THDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATV CCDS73 STLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILA 300 310 320 330 340 350 288 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:37:29 2016 done: Thu Nov 3 01:37:29 2016 Total Scan time: 2.650 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]