FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0530, 154 aa 1>>>pF1KE0530 154 - 154 aa - 154 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8810+/-0.00031; mu= 14.7397+/- 0.019 mean_var=66.9156+/-13.243, 0's: 0 Z-trim(115.9): 20 B-trim: 0 in 0/51 Lambda= 0.156787 statistics sampled from 26703 (26723) to 26703 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.313), width: 16 Scan time: 4.710 The best scores are: opt bits E(85289) XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 1030 241.1 5.2e-64 NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 1030 241.1 5.2e-64 NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 1030 241.1 5.2e-64 NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 1030 241.1 5.2e-64 NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 253 65.4 5e-11 XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 253 65.5 5.2e-11 NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 230 60.1 1.5e-09 XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 230 60.1 1.5e-09 XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 230 60.2 1.6e-09 NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 186 50.2 1.5e-06 NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 185 50.0 1.7e-06 NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 180 48.8 3.7e-06 NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 180 48.8 3.7e-06 NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 176 47.9 7e-06 NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 171 46.8 1.6e-05 NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 166 45.7 3.4e-05 NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 163 45.0 5.3e-05 NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 163 45.0 5.5e-05 XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 151 42.3 0.00034 >>XP_005261662 (OMIM: 160000) PREDICTED: myoglobin isofo (154 aa) initn: 1030 init1: 1030 opt: 1030 Z-score: 1270.1 bits: 241.1 E(85289): 5.2e-64 Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154) 10 20 30 40 50 60 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH 70 80 90 100 110 120 130 140 150 pF1KE0 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG :::::::::::::::::::::::::::::::::: XP_005 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG 130 140 150 >>NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] (154 aa) initn: 1030 init1: 1030 opt: 1030 Z-score: 1270.1 bits: 241.1 E(85289): 5.2e-64 Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154) 10 20 30 40 50 60 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH 70 80 90 100 110 120 130 140 150 pF1KE0 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG :::::::::::::::::::::::::::::::::: NP_005 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG 130 140 150 >>NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] (154 aa) initn: 1030 init1: 1030 opt: 1030 Z-score: 1270.1 bits: 241.1 E(85289): 5.2e-64 Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154) 10 20 30 40 50 60 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_976 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_976 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH 70 80 90 100 110 120 130 140 150 pF1KE0 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG :::::::::::::::::::::::::::::::::: NP_976 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG 130 140 150 >>NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] (154 aa) initn: 1030 init1: 1030 opt: 1030 Z-score: 1270.1 bits: 241.1 E(85289): 5.2e-64 Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154) 10 20 30 40 50 60 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_976 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_976 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKH 70 80 90 100 110 120 130 140 150 pF1KE0 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG :::::::::::::::::::::::::::::::::: NP_976 PGDFGADAQGAMNKALELFRKDMASNYKELGFQG 130 140 150 >>NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] (190 aa) initn: 238 init1: 126 opt: 253 Z-score: 319.0 bits: 65.4 E(85289): 5e-11 Smith-Waterman score: 253; 28.6% identity (64.3% similar) in 154 aa overlap (3-152:19-171) 10 20 30 40 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKF ::..: . : .:... :. : .:.:.: . : . . : NP_599 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 DKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPL----AQSHATKHKI ..:::... ::. : .:.::. :. ::. .... : ... . ...:: :::. NP_599 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENL-HDPDKVSSVLALVGKAHALKHKV 70 80 90 100 110 110 120 130 140 150 pF1KE0 PVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG :....: :..:. . .:: ..: : : :. . ... :::.:. NP_599 EPVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNAT 120 130 140 150 160 170 NP_599 TPPATLPSSGP 180 190 >>XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin isof (202 aa) initn: 238 init1: 126 opt: 253 Z-score: 318.6 bits: 65.5 E(85289): 5.2e-11 Smith-Waterman score: 253; 28.6% identity (64.3% similar) in 154 aa overlap (3-152:19-171) 10 20 30 40 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKF ::..: . : .:... :. : .:.:.: . : . . : XP_005 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 DKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPL----AQSHATKHKI ..:::... ::. : .:.::. :. ::. .... : ... . ...:: :::. XP_005 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENL-HDPDKVSSVLALVGKAHALKHKV 70 80 90 100 110 110 120 130 140 150 pF1KE0 PVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG :....: :..:. . .:: ..: : : :. . ... :::.:. XP_005 EPVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNAT 120 130 140 150 160 170 XP_005 THSSWRRSPEGSWGRQASCPSCC 180 190 200 >>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa) initn: 167 init1: 123 opt: 230 Z-score: 292.6 bits: 60.1 E(85289): 1.5e-09 Smith-Waterman score: 230; 28.2% identity (63.8% similar) in 149 aa overlap (1-148:1-142) 10 20 30 40 50 60 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE :.:. : .....:.:. .. : :.: ::: .::.: : .: : .: NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF------DLHPGSA 10 20 30 40 50 70 80 90 100 110 pF1KE0 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKI-PVKYLEFISECIIQVLQSK .:. ::. :..:.: .:. . .. :.. :: .. ::.. ...:.:.. .: .. NP_005 QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNF-KLLSHCLLVTLAAR 60 70 80 90 100 110 120 130 140 150 pF1KE0 HPGDFGADAQGAMNKALELFRKDMASNYKELGFQG :.:: :.:..: .: : . . .. .:. NP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR 120 130 140 >>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa) initn: 167 init1: 123 opt: 230 Z-score: 292.6 bits: 60.1 E(85289): 1.5e-09 Smith-Waterman score: 230; 28.2% identity (63.8% similar) in 149 aa overlap (1-148:1-142) 10 20 30 40 50 60 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASE :.:. : .....:.:. .. : :.: ::: .::.: : .: : .: XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF------DLHPGSA 10 20 30 40 50 70 80 90 100 110 pF1KE0 DLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKI-PVKYLEFISECIIQVLQSK .:. ::. :..:.: .:. . .. :.. :: .. ::.. ...:.:.. .: .. XP_005 QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNF-KLLSHCLLVTLAAR 60 70 80 90 100 110 120 130 140 150 pF1KE0 HPGDFGADAQGAMNKALELFRKDMASNYKELGFQG :.:: :.:..: .: : . . .. .:. XP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR 120 130 140 >>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa) initn: 167 init1: 123 opt: 230 Z-score: 292.1 bits: 60.2 E(85289): 1.6e-09 Smith-Waterman score: 230; 28.2% identity (63.8% similar) in 149 aa overlap (1-148:13-154) 10 20 30 40 pF1KE0 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFK :.:. : .....:.:. .. : :.: ::: .::.: : .: XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF- 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 HLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKI-PVKYLEF : .: .:. ::. :..:.: .:. . .. :.. :: .. ::.. .. XP_005 -----DLHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNF-KL 60 70 80 90 100 110 110 120 130 140 150 pF1KE0 ISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG .:.:.. .: .. :.:: :.:..: .: : . . .. .:. XP_005 LSHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR 120 130 140 150 >>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa) initn: 141 init1: 141 opt: 186 Z-score: 238.6 bits: 50.2 E(85289): 1.5e-06 Smith-Waterman score: 186; 25.0% identity (59.5% similar) in 148 aa overlap (1-147:1-146) 10 20 30 40 50 pF1KE0 MG-LSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKAS :: ... . . ..:::: .. : :.: ::. .: : . ::.: .:.: . . .. NP_000 MGHFTEEDKATITSLWGKV--NVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSK .: :: :::.:: .:. .. . :.. : : .. . ...... .. :: . NP_000 PKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH 60 70 80 90 100 110 120 130 140 150 pF1KE0 HPGDFGADAQGAMNKALELFRKDMASNYKELGFQG .: ..:.. .: . . ..: : NP_000 FGKEFTPEVQASWQKMVTGVASALSSRYH 120 130 140 154 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:30:19 2016 done: Thu Nov 3 01:30:20 2016 Total Scan time: 4.710 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]