FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0542, 307 aa 1>>>pF1KE0542 307 - 307 aa - 307 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8846+/-0.000525; mu= 17.6917+/- 0.032 mean_var=64.4002+/-14.047, 0's: 0 Z-trim(107.1): 268 B-trim: 602 in 1/49 Lambda= 0.159820 statistics sampled from 14905 (15203) to 14905 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.526), E-opt: 0.2 (0.178), width: 16 Scan time: 5.540 The best scores are: opt bits E(85289) NP_006349 (OMIM: 606795) peroxisomal membrane prot ( 307) 1967 462.8 3.7e-130 NP_001269655 (OMIM: 606795) peroxisomal membrane p ( 270) 1737 409.8 3.1e-114 NP_001269656 (OMIM: 606795) peroxisomal membrane p ( 234) 1249 297.2 2.1e-80 NP_110407 (OMIM: 610815,616839) mitochondrial fola ( 315) 382 97.4 3.9e-20 XP_011523400 (OMIM: 606521,607196,613710) PREDICTE ( 215) 283 74.5 2.2e-13 XP_016880417 (OMIM: 606521,607196,613710) PREDICTE ( 215) 283 74.5 2.2e-13 NP_001034444 (OMIM: 615064) mitochondrial basic am ( 303) 272 72.0 1.6e-12 XP_005263263 (OMIM: 113730,601665) PREDICTED: mito ( 306) 272 72.0 1.7e-12 XP_016869366 (OMIM: 610815,616839) PREDICTED: mito ( 183) 268 70.9 2.1e-12 NP_068605 (OMIM: 113730,601665) mitochondrial brow ( 307) 270 71.6 2.3e-12 NP_003347 (OMIM: 601665,602044) mitochondrial unco ( 312) 268 71.1 3.2e-12 XP_005257618 (OMIM: 606521,607196,613710) PREDICTE ( 320) 264 70.2 6.2e-12 XP_005257617 (OMIM: 606521,607196,613710) PREDICTE ( 320) 264 70.2 6.2e-12 XP_006722070 (OMIM: 606521,607196,613710) PREDICTE ( 320) 264 70.2 6.2e-12 XP_016880415 (OMIM: 606521,607196,613710) PREDICTE ( 320) 264 70.2 6.2e-12 NP_001119593 (OMIM: 606521,607196,613710) mitochon ( 320) 264 70.2 6.2e-12 XP_005257616 (OMIM: 606521,607196,613710) PREDICTE ( 320) 264 70.2 6.2e-12 XP_005257619 (OMIM: 606521,607196,613710) PREDICTE ( 320) 264 70.2 6.2e-12 NP_068380 (OMIM: 606521,607196,613710) mitochondri ( 320) 264 70.2 6.2e-12 NP_001119594 (OMIM: 606521,607196,613710) mitochon ( 320) 264 70.2 6.2e-12 NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 251 67.2 4.7e-11 NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 251 67.2 4.7e-11 NP_660348 (OMIM: 300641) solute carrier family 25 ( 341) 249 66.8 7.1e-11 XP_011530530 (OMIM: 113730,601665) PREDICTED: mito ( 277) 247 66.2 8.4e-11 XP_011543249 (OMIM: 610825) PREDICTED: solute carr ( 246) 241 64.8 2e-10 XP_016873051 (OMIM: 610825) PREDICTED: solute carr ( 260) 241 64.8 2.1e-10 XP_011535589 (OMIM: 607571) PREDICTED: mitochondri ( 303) 237 64.0 4.4e-10 XP_011535590 (OMIM: 607571) PREDICTED: mitochondri ( 269) 231 62.5 1.1e-09 XP_005266379 (OMIM: 610793) PREDICTED: kidney mito ( 254) 227 61.6 1.9e-09 XP_016876013 (OMIM: 610793) PREDICTED: kidney mito ( 291) 227 61.6 2.1e-09 NP_001010875 (OMIM: 610793) kidney mitochondrial c ( 291) 227 61.6 2.1e-09 XP_005266378 (OMIM: 610793) PREDICTED: kidney mito ( 293) 227 61.6 2.1e-09 XP_006719856 (OMIM: 610793) PREDICTED: kidney mito ( 293) 227 61.6 2.1e-09 XP_016876012 (OMIM: 610793) PREDICTED: kidney mito ( 293) 227 61.6 2.1e-09 XP_006719857 (OMIM: 610793) PREDICTED: kidney mito ( 293) 227 61.6 2.1e-09 NP_073714 (OMIM: 601665,602044) mitochondrial unco ( 275) 225 61.2 2.8e-09 NP_000378 (OMIM: 212138,613698) mitochondrial carn ( 301) 225 61.2 3e-09 XP_016880416 (OMIM: 606521,607196,613710) PREDICTE ( 219) 219 59.7 6.1e-09 NP_001158268 (OMIM: 611037,616794) S-adenosylmethi ( 186) 217 59.2 7.4e-09 XP_011531629 (OMIM: 611037,616794) PREDICTED: S-ad ( 186) 217 59.2 7.4e-09 NP_003553 (OMIM: 604165) mitochondrial 2-oxoglutar ( 314) 219 59.8 8.1e-09 NP_775742 (OMIM: 611037,616794) S-adenosylmethioni ( 274) 217 59.3 1e-08 NP_001158889 (OMIM: 604165) mitochondrial 2-oxoglu ( 303) 217 59.3 1.1e-08 NP_077008 (OMIM: 608746) calcium-binding mitochond ( 468) 215 59.0 2.1e-08 XP_011526586 (OMIM: 608746) PREDICTED: calcium-bin ( 469) 215 59.0 2.1e-08 XP_016882777 (OMIM: 608746) PREDICTED: calcium-bin ( 484) 215 59.0 2.1e-08 XP_011526585 (OMIM: 608746) PREDICTED: calcium-bin ( 490) 215 59.0 2.2e-08 XP_011526584 (OMIM: 608746) PREDICTED: calcium-bin ( 503) 215 59.0 2.2e-08 XP_011526583 (OMIM: 608746) PREDICTED: calcium-bin ( 515) 215 59.1 2.3e-08 XP_011526582 (OMIM: 608746) PREDICTED: calcium-bin ( 531) 215 59.1 2.3e-08 >>NP_006349 (OMIM: 606795) peroxisomal membrane protein (307 aa) initn: 1967 init1: 1967 opt: 1967 Z-score: 2457.6 bits: 462.8 E(85289): 3.7e-130 Smith-Waterman score: 1967; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KE0 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMG 250 260 270 280 290 300 pF1KE0 LKRAHQH ::::::: NP_006 LKRAHQH >>NP_001269655 (OMIM: 606795) peroxisomal membrane prote (270 aa) initn: 1737 init1: 1737 opt: 1737 Z-score: 2171.8 bits: 409.8 E(85289): 3.1e-114 Smith-Waterman score: 1737; 99.6% identity (100.0% similar) in 269 aa overlap (39-307:2-270) 10 20 30 40 50 60 pF1KE0 SLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGW .::::::::::::::::::::::::::::: NP_001 MIDEKRKSKTTHMVLLEIIKEEGLLAPYRGW 10 20 30 70 80 90 100 110 120 pF1KE0 FPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 LKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 LKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 NILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH 220 230 240 250 260 270 >>NP_001269656 (OMIM: 606795) peroxisomal membrane prote (234 aa) initn: 1464 init1: 1249 opt: 1249 Z-score: 1564.6 bits: 297.2 E(85289): 2.1e-80 Smith-Waterman score: 1322; 76.2% identity (76.2% similar) in 307 aa overlap (1-307:1-234) 10 20 30 40 50 60 pF1KE0 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEG :::::::::::::::::::::::::::::::::::::: NP_001 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQ---------------------- 10 20 30 70 80 90 100 110 120 pF1KE0 LLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTT ::::::::: NP_001 ---------------------------------------------------GVVNVLLTT 40 130 140 150 160 170 180 pF1KE0 PLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPA 50 60 70 80 90 100 190 200 210 220 230 240 pF1KE0 IQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPE 110 120 130 140 150 160 250 260 270 280 290 300 pF1KE0 NRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMG 170 180 190 200 210 220 pF1KE0 LKRAHQH ::::::: NP_001 LKRAHQH 230 >>NP_110407 (OMIM: 610815,616839) mitochondrial folate t (315 aa) initn: 283 init1: 119 opt: 382 Z-score: 482.4 bits: 97.4 E(85289): 3.9e-20 Smith-Waterman score: 382; 29.3% identity (62.6% similar) in 297 aa overlap (7-292:23-304) 10 20 30 40 pF1KE0 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDE--- ::.:. ::. :.: . .. ::: ...:. :.. NP_110 MTGQGQSASGSSAWSTVFRHVRYENLI---AGVSGGVLSNLALHPLDLVKIRFAVSDGLE 10 20 30 40 50 50 60 70 80 90 pF1KE0 -KRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKG--QH . : . : : : .:: . :.: : : . : .::. .:..:. ..: .. NP_110 LRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAER 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 STTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIR . . :: . ::.... .:.::::..::: :: : .:::..:.. .: . NP_110 LEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSP--HRQYKGMFDTLVKIYK 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 DEGISALWNGTFPSLLLVFNPAIQFMFYEGLK---RQLLKK--RMKLSSLDVFIIGAVAK ::. .:..: :.:. . . :.::: :: :: : ... . .::... . ..:..: NP_110 YEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSK 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 AIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAK .:...::: :.: : ::. .. .. .. .. . :. :. :.:::. . NP_110 IFAVAATYPYQVV-------RARLQDQHMFYSG---VIDVITKTWRKEGVGGFYKGIAPN 240 250 260 270 280 280 290 300 pF1KE0 LLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH :.... . . :.:::... NP_110 LIRVTPACCITFVVYENVSHFLLDLREKRK 290 300 310 >>XP_011523400 (OMIM: 606521,607196,613710) PREDICTED: m (215 aa) initn: 235 init1: 94 opt: 283 Z-score: 361.4 bits: 74.5 E(85289): 2.2e-13 Smith-Waterman score: 283; 28.8% identity (68.2% similar) in 198 aa overlap (96-289:10-199) 70 80 90 100 110 120 pF1KE0 RGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVV :...: . :.: :.:.:. : .:. :. XP_011 MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVI 10 20 30 130 140 150 160 170 180 pF1KE0 NTRLKLQGAKFRNEDIVPT-NYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFN-PAIQF . :..:: .. : :. .:.::..: .::...:: .:.:.: :. .: .. :.:: XP_011 KIRFQLQHERLSRSD--PSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQF 40 50 60 70 80 90 190 200 210 220 230 240 pF1KE0 MFYEGLKRQLLKKRM-KLSSLDV-FIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPEN . .: : . . . . ..: :. :..: .:: ...:...... ::. . .:. XP_011 LSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRT--RFAAQG-EPKV 100 110 120 130 140 150 250 260 270 280 290 300 pF1KE0 RTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGL : .... .: ... : .:..::: .::...:....::. :: XP_011 RR---YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCMNRT 160 170 180 190 200 210 pF1KE0 KRAHQH XP_011 ASQR >>XP_016880417 (OMIM: 606521,607196,613710) PREDICTED: m (215 aa) initn: 235 init1: 94 opt: 283 Z-score: 361.4 bits: 74.5 E(85289): 2.2e-13 Smith-Waterman score: 283; 28.8% identity (68.2% similar) in 198 aa overlap (96-289:10-199) 70 80 90 100 110 120 pF1KE0 RGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVV :...: . :.: :.:.:. : .:. :. XP_016 MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVI 10 20 30 130 140 150 160 170 180 pF1KE0 NTRLKLQGAKFRNEDIVPT-NYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFN-PAIQF . :..:: .. : :. .:.::..: .::...:: .:.:.: :. .: .. :.:: XP_016 KIRFQLQHERLSRSD--PSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQF 40 50 60 70 80 90 190 200 210 220 230 240 pF1KE0 MFYEGLKRQLLKKRM-KLSSLDV-FIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPEN . .: : . . . . ..: :. :..: .:: ...:...... ::. . .:. XP_016 LSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRT--RFAAQG-EPKV 100 110 120 130 140 150 250 260 270 280 290 300 pF1KE0 RTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGL : .... .: ... : .:..::: .::...:....::. :: XP_016 RR---YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCMNRT 160 170 180 190 200 210 pF1KE0 KRAHQH XP_016 ASQR >>NP_001034444 (OMIM: 615064) mitochondrial basic amino (303 aa) initn: 282 init1: 80 opt: 272 Z-score: 345.6 bits: 72.0 E(85289): 1.6e-12 Smith-Waterman score: 302; 29.4% identity (58.8% similar) in 279 aa overlap (14-285:6-266) 10 20 30 40 50 pF1KE0 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVD--EKRKSKTTHMVLLEIIKE .:: .:.:... : :.::...::::. :: . . : . :::. NP_001 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQ 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EGLLAPYRGW-FPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVL :..:. :.: :... . .:. :.:.:: : :.. .....: .::... . NP_001 ESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRAL---G-HDSPLNQFLAGAAAGAIQCV 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 LTTPLWVVNTRLKLQGAKFRNEDIVPT-NYKGIIDAFHQIIRDEGISALWNGTFPSLLLV . :. ...:::.:: : :. .::: .: . :: ::. .. : : :: NP_001 ICCPMELAKTRLQLQ-------DAGPARTYKGSLDCLAQIYGHEGLRGVNRGMV-STLLR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 FNPA--IQFMFYEGLKRQL-LKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFG .:. . :. :..: : : . .: ... :... .. :::...:.: :. NP_001 ETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 RHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTA : :. :.:: .:: : : . .:: . ::.. . : : NP_001 GLRGAPR------YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLT 230 240 250 260 270 300 pF1KE0 ATFTVMGLKRAHQH NP_001 YARGEEAGPEGEAVPAAPAGPALAQPSSL 280 290 300 >>XP_005263263 (OMIM: 113730,601665) PREDICTED: mitochon (306 aa) initn: 204 init1: 92 opt: 272 Z-score: 345.5 bits: 72.0 E(85289): 1.7e-12 Smith-Waterman score: 272; 23.4% identity (58.8% similar) in 291 aa overlap (11-291:15-291) 10 20 30 40 50 pF1KE0 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKS------KTTHM :. ...... : .. ::::::..::::. . . : . XP_005 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLG 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 VLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTT-GKDLVVGF .. ..: :: . : : .. : . . ..... . . :... . :. ...:. XP_005 TITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETPSLGSKILAGL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 VAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGT ..: : :.. : ::..::. :. . . : : : : .:.. : ::...::.:: XP_005 TTGGVAVFIGQPTEVVKVRLQAQS---HLHGIKPR-YTGTYNAYRIIATTEGLTGLWKGT 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 FPSLL--LVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGA-VAKAIATTVTYPLQTV :.:. ...: ... :. .:. ..:. . ... ...: .: ::... :...: XP_005 TPNLMRSVIIN-CTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVV 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 QSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFL .. :: : :. ... . : ...::: ..:. ..::. XP_005 KT--RFI-------NSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFV 240 250 260 270 280 290 300 pF1KE0 VYEKLTAATFTVMGLKRAHQH .:.: XP_005 CFEQLKRELSKSRQTMDCAT 290 300 >>XP_016869366 (OMIM: 610815,616839) PREDICTED: mitochon (183 aa) initn: 216 init1: 119 opt: 268 Z-score: 343.6 bits: 70.9 E(85289): 2.1e-12 Smith-Waterman score: 268; 30.6% identity (65.6% similar) in 180 aa overlap (118-292:5-172) 90 100 110 120 130 140 pF1KE0 SLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYK .:.::::..::: :: : .:: XP_016 MTLCITNPLWVTKTRLMLQYDAVVNSP--HRQYK 10 20 30 150 160 170 180 190 200 pF1KE0 GIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLK---RQLLKK--RMKLSS :..:.. .: . ::. .:..: :.:. . . :.::: :: :: : ... . .::. XP_016 GMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLST 40 50 60 70 80 90 210 220 230 240 250 260 pF1KE0 LDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFG .. . ..:..: .:...::: :.: : ::. .. . ... .. . :. : XP_016 VEYISVAALSKIFAVAATYPYQVV-------RARLQDQHMFYS---GVIDVITKTWRKEG 100 110 120 130 140 270 280 290 300 pF1KE0 IMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH . :.:::. .:.... . . :.:::... XP_016 VGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLREKRK 150 160 170 180 >>NP_068605 (OMIM: 113730,601665) mitochondrial brown fa (307 aa) initn: 204 init1: 92 opt: 270 Z-score: 343.0 bits: 71.6 E(85289): 2.3e-12 Smith-Waterman score: 270; 23.3% identity (58.6% similar) in 292 aa overlap (11-291:15-292) 10 20 30 40 50 pF1KE0 MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKS------KTTHM :. ...... : .. ::::::..::::. . . : . NP_068 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLG 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 VLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHS--TTGKDLVVG .. ..: :: . : : .. : . . ..... . . :... . :. ...: NP_068 TITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 FVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNG ...: : :.. : ::..::. :. . . : : : : .:.. : ::...::.: NP_068 LTTGGVAVFIGQPTEVVKVRLQAQS---HLHGIKPR-YTGTYNAYRIIATTEGLTGLWKG 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 TFPSLL--LVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGA-VAKAIATTVTYPLQT : :.:. ...: ... :. .:. ..:. . ... ...: .: ::... :... NP_068 TTPNLMRSVIIN-CTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDV 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 VQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMF :.. :: : :. ... . : ...::: ..:. ..:: NP_068 VKT--RFI-------NSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMF 240 250 260 270 280 290 300 pF1KE0 LVYEKLTAATFTVMGLKRAHQH . .:.: NP_068 VCFEQLKRELSKSRQTMDCAT 290 300 307 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:21:59 2016 done: Thu Nov 3 00:22:00 2016 Total Scan time: 5.540 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]