FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0545, 377 aa 1>>>pF1KE0545 377 - 377 aa - 377 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6977+/-0.000371; mu= 14.4966+/- 0.023 mean_var=65.1556+/-13.486, 0's: 0 Z-trim(112.3): 18 B-trim: 1193 in 1/51 Lambda= 0.158891 statistics sampled from 21109 (21123) to 21109 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.248), width: 16 Scan time: 7.550 The best scores are: opt bits E(85289) NP_001008566 (OMIM: 603126) protein-tyrosine sulfo ( 377) 2502 582.4 5.7e-166 NP_003586 (OMIM: 603126) protein-tyrosine sulfotra ( 377) 2502 582.4 5.7e-166 XP_006724401 (OMIM: 603126) PREDICTED: protein-tyr ( 431) 2502 582.4 6.4e-166 NP_003587 (OMIM: 603125) protein-tyrosine sulfotra ( 370) 1625 381.4 1.8e-105 XP_016868216 (OMIM: 603125) PREDICTED: protein-tyr ( 370) 1625 381.4 1.8e-105 XP_016868215 (OMIM: 603125) PREDICTED: protein-tyr ( 370) 1625 381.4 1.8e-105 XP_016868214 (OMIM: 603125) PREDICTED: protein-tyr ( 370) 1625 381.4 1.8e-105 XP_016868213 (OMIM: 603125) PREDICTED: protein-tyr ( 376) 1623 380.9 2.6e-105 XP_005250699 (OMIM: 603125) PREDICTED: protein-tyr ( 376) 1623 380.9 2.6e-105 XP_011514937 (OMIM: 603125) PREDICTED: protein-tyr ( 353) 1580 371.1 2.3e-102 XP_011514936 (OMIM: 603125) PREDICTED: protein-tyr ( 353) 1580 371.1 2.3e-102 >>NP_001008566 (OMIM: 603126) protein-tyrosine sulfotran (377 aa) initn: 2502 init1: 2502 opt: 2502 Z-score: 3100.7 bits: 582.4 E(85289): 5.7e-166 Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 MVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 WTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLK 310 320 330 340 350 360 370 pF1KE0 GYFQVNQNSTSSHLGSS ::::::::::::::::: NP_001 GYFQVNQNSTSSHLGSS 370 >>NP_003586 (OMIM: 603126) protein-tyrosine sulfotransfe (377 aa) initn: 2502 init1: 2502 opt: 2502 Z-score: 3100.7 bits: 582.4 E(85289): 5.7e-166 Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 MVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 WTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 WTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLK 310 320 330 340 350 360 370 pF1KE0 GYFQVNQNSTSSHLGSS ::::::::::::::::: NP_003 GYFQVNQNSTSSHLGSS 370 >>XP_006724401 (OMIM: 603126) PREDICTED: protein-tyrosin (431 aa) initn: 2502 init1: 2502 opt: 2502 Z-score: 3099.7 bits: 582.4 E(85289): 6.4e-166 Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:55-431) 10 20 30 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLE :::::::::::::::::::::::::::::: XP_006 RCEPGGLPANLSLKPQKRALRPGLPCLRPSMRLSVRRVLLAAGCALVLVLAVQLGQQVLE 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 CRAVLAGLRSPRGAMRPEQEELVMVGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CRAVLAGLRSPRGAMRPEQEELVMVGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDA 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 HPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGE 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDC 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE0 LTKWNKAIEVMYAQCMEVGKEKCLPVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTKWNKAIEVMYAQCMEVGKEKCLPVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDL 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE0 IGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYAN 330 340 350 360 370 380 340 350 360 370 pF1KE0 PPNYGNPDPFVINNTQRVLKGDYKTPANLKGYFQVNQNSTSSHLGSS ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPNYGNPDPFVINNTQRVLKGDYKTPANLKGYFQVNQNSTSSHLGSS 390 400 410 420 430 >>NP_003587 (OMIM: 603125) protein-tyrosine sulfotransfe (370 aa) initn: 1635 init1: 1597 opt: 1625 Z-score: 2014.3 bits: 381.4 E(85289): 1.8e-105 Smith-Waterman score: 1625; 65.9% identity (84.6% similar) in 369 aa overlap (5-367:5-368) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . NP_003 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: NP_003 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: NP_003 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. NP_003 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: NP_003 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.:: ::... NP_003 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQ 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS : :: :..: NP_003 LPDFLKEKPQTEQVE 360 370 >>XP_016868216 (OMIM: 603125) PREDICTED: protein-tyrosin (370 aa) initn: 1635 init1: 1597 opt: 1625 Z-score: 2014.3 bits: 381.4 E(85289): 1.8e-105 Smith-Waterman score: 1625; 65.9% identity (84.6% similar) in 369 aa overlap (5-367:5-368) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . XP_016 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: XP_016 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: XP_016 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. XP_016 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: XP_016 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.:: ::... XP_016 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQ 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS : :: :..: XP_016 LPDFLKEKPQTEQVE 360 370 >>XP_016868215 (OMIM: 603125) PREDICTED: protein-tyrosin (370 aa) initn: 1635 init1: 1597 opt: 1625 Z-score: 2014.3 bits: 381.4 E(85289): 1.8e-105 Smith-Waterman score: 1625; 65.9% identity (84.6% similar) in 369 aa overlap (5-367:5-368) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . XP_016 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: XP_016 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: XP_016 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. XP_016 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: XP_016 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.:: ::... XP_016 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQ 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS : :: :..: XP_016 LPDFLKEKPQTEQVE 360 370 >>XP_016868214 (OMIM: 603125) PREDICTED: protein-tyrosin (370 aa) initn: 1635 init1: 1597 opt: 1625 Z-score: 2014.3 bits: 381.4 E(85289): 1.8e-105 Smith-Waterman score: 1625; 65.9% identity (84.6% similar) in 369 aa overlap (5-367:5-368) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . XP_016 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: XP_016 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: XP_016 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. XP_016 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: XP_016 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.:: ::... XP_016 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQ 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS : :: :..: XP_016 LPDFLKEKPQTEQVE 360 370 >>XP_016868213 (OMIM: 603125) PREDICTED: protein-tyrosin (376 aa) initn: 1638 init1: 1600 opt: 1623 Z-score: 2011.7 bits: 380.9 E(85289): 2.6e-105 Smith-Waterman score: 1623; 66.2% identity (84.5% similar) in 367 aa overlap (5-365:5-366) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . XP_016 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: XP_016 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: XP_016 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. XP_016 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: XP_016 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.:: ::... XP_016 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQ 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS : :: :: XP_016 LPDFLKEKPQVLCLLFPPDVY 360 370 >>XP_005250699 (OMIM: 603125) PREDICTED: protein-tyrosin (376 aa) initn: 1638 init1: 1600 opt: 1623 Z-score: 2011.7 bits: 380.9 E(85289): 2.6e-105 Smith-Waterman score: 1623; 66.2% identity (84.5% similar) in 367 aa overlap (5-365:5-366) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . XP_005 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: XP_005 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: XP_005 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. XP_005 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: XP_005 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.:: ::... XP_005 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQ 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS : :: :: XP_005 LPDFLKEKPQVLCLLFPPDVY 360 370 >>XP_011514937 (OMIM: 603125) PREDICTED: protein-tyrosin (353 aa) initn: 1612 init1: 1545 opt: 1580 Z-score: 1958.9 bits: 371.1 E(85289): 2.3e-102 Smith-Waterman score: 1580; 67.3% identity (85.7% similar) in 349 aa overlap (5-347:5-348) 10 20 30 40 50 pF1KE0 MRLSVRRVLLAAGCALVLVLAVQLGQQVLEC------RAVLAGLRSPRGAMRPEQEELVM ... :: : .. : . :::...:: :. . :.: : ..: . XP_011 MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLD---- 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWS . .:.. . : : :::::.:::::::::::::::::::..:::::::.:::.::..: :: XP_011 LKANKT-FAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFP .:..::.:::::::::::::.:::::.::.:.:::::: :::::::.::: .::::::: XP_011 RSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCL :.:::::::::::::::::.::::::::::.::::::::::.:::.:: :::::: .::. XP_011 NAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 PVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVN :.::::::::.: .. .: :: : :. .:::::..::: :::::::.:::::::::::: XP_011 LVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYK . :::::.:.:: ::..::: ::::::.:::::::::::::.::: .:.::.: XP_011 VGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRTEQVE 300 310 320 330 340 350 360 370 pF1KE0 TPANLKGYFQVNQNSTSSHLGSS 377 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:03:37 2016 done: Thu Nov 3 00:03:38 2016 Total Scan time: 7.550 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]