FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0547, 423 aa 1>>>pF1KE0547 423 - 423 aa - 423 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2687+/-0.000996; mu= 17.3469+/- 0.060 mean_var=64.5972+/-12.786, 0's: 0 Z-trim(104.1): 31 B-trim: 378 in 1/50 Lambda= 0.159576 statistics sampled from 7720 (7740) to 7720 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.238), width: 16 Scan time: 2.080 The best scores are: opt bits E(32554) CCDS14043.1 TTLL1 gene_id:25809|Hs108|chr22 ( 423) 2864 668.4 3.7e-192 CCDS5301.1 TTLL2 gene_id:83887|Hs108|chr6 ( 592) 536 132.5 1.1e-30 CCDS42863.1 TTLL9 gene_id:164395|Hs108|chr20 ( 439) 422 106.2 6.5e-23 CCDS56237.1 TTLL3 gene_id:100526693|Hs108|chr3 ( 625) 388 98.4 2e-20 CCDS43048.2 TTLL3 gene_id:26140|Hs108|chr3 ( 915) 388 98.5 2.8e-20 CCDS44036.1 TTLL10 gene_id:254173|Hs108|chr1 ( 673) 351 89.9 7.8e-18 CCDS2096.1 TTL gene_id:150465|Hs108|chr2 ( 377) 300 78.1 1.6e-14 CCDS6834.2 TTLL11 gene_id:158135|Hs108|chr9 ( 538) 293 76.5 6.8e-14 CCDS48012.1 TTLL11 gene_id:158135|Hs108|chr9 ( 800) 293 76.6 9.4e-14 CCDS32124.1 TTLL5 gene_id:23093|Hs108|chr14 (1281) 295 77.2 1e-13 CCDS2422.1 TTLL4 gene_id:9654|Hs108|chr2 (1199) 283 74.4 6.5e-13 CCDS45724.1 TTLL6 gene_id:284076|Hs108|chr17 ( 891) 276 72.7 1.6e-12 CCDS690.2 TTLL7 gene_id:79739|Hs108|chr1 ( 887) 258 68.6 2.7e-11 CCDS8.1 TTLL10 gene_id:254173|Hs108|chr1 ( 404) 250 66.6 5.1e-11 >>CCDS14043.1 TTLL1 gene_id:25809|Hs108|chr22 (423 aa) initn: 2864 init1: 2864 opt: 2864 Z-score: 3563.4 bits: 668.4 E(32554): 3.7e-192 Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423) 10 20 30 40 50 60 pF1KE0 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT 370 380 390 400 410 420 pF1KE0 TWK ::: CCDS14 TWK >>CCDS5301.1 TTLL2 gene_id:83887|Hs108|chr6 (592 aa) initn: 603 init1: 246 opt: 536 Z-score: 664.7 bits: 132.5 E(32554): 1.1e-30 Smith-Waterman score: 680; 34.6% identity (61.0% similar) in 367 aa overlap (8-359:91-419) 10 20 30 pF1KE0 MAGKVKWVTDIEKSVLINNFEKRGWV----QVTENED : . .:. . . .::: : . :: CCDS53 PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED 70 80 90 100 110 120 40 50 60 70 80 90 pF1KE0 WNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGS ::.:: . . : . .. : .:: :. .::::: ..:..:..:. CCDS53 WNLYWRT-----SSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMY----- 130 140 150 160 170 100 110 120 130 140 pF1KE0 PLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRK------SPSSTWIMKPCGKAQGKG : :: .:.:.:...: ::. :: :. . . : :: :: ..:.: CCDS53 --------GTSLY-QFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRG 180 190 200 210 220 150 160 170 180 190 200 pF1KE0 IFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYR :.. .:..: . : . :... ::.:::::: : :::.:: :. .. CCDS53 ILI---FSDFKDFIFD------------DMYIVQKYISNPLLIGRYKCDLRIYVCVTGFK 230 240 250 260 210 220 230 240 250 260 pF1KE0 PLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHI-----HGGKWTV :: :.:. :. :: : :. . :.:.: ..:::: .:.: : .:..: :: :::. CCDS53 PLTIYVYQEGLVRFATEKF--DLSNLQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTL 270 280 290 300 310 320 270 280 290 300 310 320 pF1KE0 SNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKP : . ::.: .. :. .:: ... .. :.:: . .::: .:.::.:::.::: CCDS53 SRFFSYLRSWDVDDLL--LWKKIHRMVILTILAIAPSVPFAANCFELFGFDILIDDNLKP 330 340 350 360 370 380 330 340 350 360 370 380 pF1KE0 WLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILY ::.::: ::.:: . ..: ..: .:..: ... :: CCDS53 WLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGLRNEGREASNATHGNSNIDAAKS 390 400 410 420 430 440 390 400 410 420 pF1KE0 DEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK CCDS53 DRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLSTR 450 460 470 480 490 500 >>CCDS42863.1 TTLL9 gene_id:164395|Hs108|chr20 (439 aa) initn: 1008 init1: 421 opt: 422 Z-score: 524.8 bits: 106.2 E(32554): 6.5e-23 Smith-Waterman score: 958; 45.0% identity (69.5% similar) in 371 aa overlap (14-370:52-392) 10 20 30 40 pF1KE0 MAGKVKWVTDIEKSVLINNFEKR-GWVQVTENEDWNFYWMSVQ ..:.. ...: :::.: .. .:.::: .:. CCDS42 LQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVS 30 40 50 60 70 80 50 60 70 80 90 100 pF1KE0 TIRNVFSVEAGYRLSDDQI-VNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDEN .:. :. . :... ..:: ::::::::. ::::.::.::.::.: : : : CCDS42 WLRENFD----HTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLERE----AGKLEA 90 100 110 120 130 110 120 130 140 150 160 pF1KE0 GKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWS .: :: : :. .: .:.::::::::.:. :::::: ...:::::::. .:..: : CCDS42 AK---CDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWR 140 150 160 170 180 190 170 180 190 200 210 pF1KE0 RDSKTSSFVSQSNK---EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGF .:...:. .:.. : :: . ::.:: ::::::::::.:::: . .: ... : CCDS42 KDTRSSD--DQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSVFA-ECLLWS-GH 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 CRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVT : : :::::::.:: . ::. .: :::.. .: :: : .: :.. CCDS42 RR------------QD---VHLTNVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAV 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 SKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTA :: .: :.:.::..: :. .:::::: :::::.::. :::::.:::::::::.:. CCDS42 ETLFRDIDNIFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQ 300 310 320 330 340 350 340 350 360 370 380 pF1KE0 NDRILKYNLINDTLNIAVPNGEIP---------DCKWNKSPPKEVLGNYEILYDEELAQG .: :: :..:::... .... : :: .: CCDS42 EDYELKTCLLEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTN 360 370 380 390 400 410 390 400 410 420 pF1KE0 DGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK CCDS42 THLGCVNDRKKQLRQLFCSLQVQKKASS 420 430 >>CCDS56237.1 TTLL3 gene_id:100526693|Hs108|chr3 (625 aa) initn: 379 init1: 144 opt: 388 Z-score: 480.2 bits: 98.4 E(32554): 2e-20 Smith-Waterman score: 388; 32.5% identity (63.6% similar) in 228 aa overlap (135-356:341-560) 110 120 130 140 150 160 pF1KE0 LYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDS ::.:: .:..:.::. ...: .. : . CCDS56 LDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGN 320 330 340 350 360 370 170 180 190 200 210 220 pF1KE0 KTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTV . : ...: .:.. ::. :::: : ::::: . ::. . :: ..:. .. :: : CCDS56 PV---VMKDGK--WVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQ 380 390 400 410 420 230 240 250 260 270 pF1KE0 KYTPSTSELDNMFVHLTNVAIQKHGEDYNHIH-----GGKWTVSNLRLYLESTRGKEVTS . : ..::: ::: : .:::: :. : : . :. . .. .:. . .. : CCDS56 PF--SLKNLDNS-VHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAWS 430 440 450 460 470 480 280 290 300 310 320 330 pF1KE0 KLF-DEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTA .. .. ....:.. ... : :: :: :... . ..:::::.::::... ::: CCDS56 TIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTA 490 500 510 520 530 540 340 350 360 370 380 390 pF1KE0 NDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRS : .. ::: ... CCDS56 VTARLCAGVQADTLRVVIDRMLDRNCDTGAFELIYKQPVTTSPASTPRPSCLLPMYSDTR 550 560 570 580 590 600 >>CCDS43048.2 TTLL3 gene_id:26140|Hs108|chr3 (915 aa) initn: 379 init1: 144 opt: 388 Z-score: 477.7 bits: 98.5 E(32554): 2.8e-20 Smith-Waterman score: 388; 32.5% identity (63.6% similar) in 228 aa overlap (135-356:423-642) 110 120 130 140 150 160 pF1KE0 LYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDS ::.:: .:..:.::. ...: .. : . CCDS43 LDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGN 400 410 420 430 440 450 170 180 190 200 210 220 pF1KE0 KTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTV . : ...: .:.. ::. :::: : ::::: . ::. . :: ..:. .. :: : CCDS43 PV---VMKDGK--WVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQ 460 470 480 490 500 230 240 250 260 270 pF1KE0 KYTPSTSELDNMFVHLTNVAIQKHGEDYNHIH-----GGKWTVSNLRLYLESTRGKEVTS . : ..::: ::: : .:::: :. : : . :. . .. .:. . .. : CCDS43 PF--SLKNLDNS-VHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAWS 510 520 530 540 550 560 280 290 300 310 320 330 pF1KE0 KLF-DEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTA .. .. ....:.. ... : :: :: :... . ..:::::.::::... ::: CCDS43 TIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTA 570 580 590 600 610 620 340 350 360 370 380 390 pF1KE0 NDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRS : .. ::: ... CCDS43 VTARLCAGVQADTLRVVIDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKKP 630 640 650 660 670 680 >>CCDS44036.1 TTLL10 gene_id:254173|Hs108|chr1 (673 aa) initn: 294 init1: 110 opt: 351 Z-score: 433.6 bits: 89.9 E(32554): 7.8e-18 Smith-Waterman score: 382; 25.8% identity (57.0% similar) in 384 aa overlap (14-356:167-541) 10 20 30 40 pF1KE0 MAGKVKWVTDIEKSVLINNFEK-RGWVQVTEN--EDWNFYWMS ...:... : .:: .. .. .:... : CCDS44 LLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQRIHDSRRDDYTLKWCE 140 150 160 170 180 190 50 60 70 80 90 pF1KE0 VQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKE----GSPLA :.. . : . : .:.. ..::. :: : ...... . . : :. : CCDS44 VKSRDSYGSFREG-----EQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGVQA 200 210 220 230 240 250 100 110 120 130 pF1KE0 --EKDENGKYL---------YLDFVPVTYM---LPADYNLFVEEFRKS------PSSTWI ::: . : :: : : .: : : ... :.. .. :: CCDS44 RLEKDAAAPALEDLPWTSPGYLRPQRVLRMEEFFPETYRLDLKHEREAFFTLFDETQIWI 260 270 280 290 300 310 140 150 160 170 180 190 pF1KE0 MKPCGKAQGKGIFLI---NKLSQIKKWSRDSKTSSFVSQS---NKEAYVISLYINNPLLI :: .. :::::::. .... .. .:. . . . .. . .: :.. ::.::::. CCDS44 CKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLV 320 330 340 350 360 370 200 210 220 230 240 250 pF1KE0 GGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGE :::::.: :.:.. : . . :. :. : : .:.: . :::: .::.. CCDS44 DGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYDPHSSDLGG---HLTNQFMQKKSP 380 390 400 410 420 260 270 280 290 300 pF1KE0 DYNHIHGGK-WTVSNLRLYLEST----RG--KE-VTSKLFDEIHWIIVQSLKAVAPVMNN : .. :.. .: :. .: :: :. : . : ... :... . :. : .. CCDS44 LYMLLKEHTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLAAKPKLDC 430 440 450 460 470 480 310 320 330 340 350 360 pF1KE0 DKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIP :. : :..:::..: ::.:.:..:.: .. . . ... .::.... CCDS44 KLGYFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLVLETFRKS 490 500 510 520 530 540 370 380 390 400 410 420 pF1KE0 DCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTW CCDS44 LRGQKMLPLLSQRRFVLLHNGEADPRPHLGGSCSLRRWPPLPTRQAKSSGPPMPHAPDQP 550 560 570 580 590 600 >>CCDS2096.1 TTL gene_id:150465|Hs108|chr2 (377 aa) initn: 243 init1: 63 opt: 300 Z-score: 374.0 bits: 78.1 E(32554): 1.6e-14 Smith-Waterman score: 300; 25.8% identity (58.3% similar) in 333 aa overlap (60-371:60-371) 30 40 50 60 70 80 pF1KE0 ENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELE :.::.. . .: :: .:: :: :: CCDS20 LRRDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKT-SPELA 30 40 50 60 70 80 90 100 110 120 130 pF1KE0 KEGS---------PLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEF-RKSPS---STWI . . : : . :.. . ..:. . ::. . ..:: CCDS20 ESCTWFPESYVIYPTNLKTPVAPAQNGIQPPISNSRTDEREFFLASYNRKKEDGEGNVWI 90 100 110 120 130 140 140 150 160 170 180 190 pF1KE0 MKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLI--GGRK : . :.:.::.. .. :.. .:...... ..::. :...:::. : :: CCDS20 AKSSAGAKGEGILISSEASEL---------LDFIDNQGQ-VHVIQKYLEHPLLLEPGHRK 150 160 170 180 190 200 210 220 230 240 250 pF1KE0 FDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQK-HGEDYN ::.: .:::. . :.:. : : . : ...... :::: ::: ....:. CCDS20 FDIRSWVLVDHQYNI--YLYREGVLRTASEPY--HVDNFQDKTCHLTNHCIQKEYSKNYG 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HIH-GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH----CFE . . :.. ... :: :. . . :... .:. :: . : .: :.... :: :. CCDS20 KYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAIST-KHLPYQSFQ 260 270 280 290 300 310 310 320 330 340 350 360 pF1KE0 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK .:.:...:..:: ::::::..:. ... . : .... ... . : :: . . CCDS20 LFGFDFMVDEELKVWLIEVNGAPACAQKLYAE--LCQGIVDIAISSVFPP---PDVEQPQ 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 SPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK . : CCDS20 TQPAAFIKL 370 >>CCDS6834.2 TTLL11 gene_id:158135|Hs108|chr9 (538 aa) initn: 251 init1: 160 opt: 293 Z-score: 363.0 bits: 76.5 E(32554): 6.8e-14 Smith-Waterman score: 355; 29.5% identity (60.2% similar) in 261 aa overlap (53-298:259-492) 30 40 50 60 70 pF1KE0 RGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQI----VNHFPNHYELTRKDLMV : . :..: ::.::. :..:: . CCDS68 SLDALKISIRQLKWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLS 230 240 250 260 270 280 80 90 100 110 120 130 pF1KE0 KNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFR--KSPSSTW- . .. ... . .: .: : ...:: ...::: . . :. . .: CCDS68 RAVRTMQNLFPEE---------------YNFYPRSWILPDEFQLFVAQVQMVKDDDPSWK 290 300 310 320 330 140 150 160 170 180 190 pF1KE0 ---IMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGG :.:: : :: ::.::. :.:. ... ... :.. :: .:::: CCDS68 PTFIVKPDGGCQGDGIYLIKDPSDIR----------LAGTLQSRPAVVQEYICKPLLIDK 340 350 360 370 380 200 210 220 230 240 250 pF1KE0 RKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYT-PSTSELDNMFVHLTNVAIQKHGED :::.:::::... ::. :. : :. :::: : :. ..: .:.:::: ... :. . CCDS68 LKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGN 390 400 410 420 430 440 260 270 280 290 300 pF1KE0 YNHIH----GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCF . : :.: : :.. : :..: .. .:....: ...... :..: CCDS68 FIHSDSASTGSKRTFSSILCRL-SSKGVDI-KKVWSDIISVVIKTVIALTPELKVFYQSD 450 460 470 480 490 500 310 320 330 340 350 360 pF1KE0 ECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWN CCDS68 IPTGRPGPTCFQVTIASSQPAFPALTGLKRALWLRVG 510 520 530 >>CCDS48012.1 TTLL11 gene_id:158135|Hs108|chr9 (800 aa) initn: 348 init1: 160 opt: 293 Z-score: 360.4 bits: 76.6 E(32554): 9.4e-14 Smith-Waterman score: 434; 28.1% identity (57.2% similar) in 388 aa overlap (53-408:259-615) 30 40 50 60 70 pF1KE0 RGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQI----VNHFPNHYELTRKDLMV : . :..: ::.::. :..:: . CCDS48 SLDALKISIRQLKWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLS 230 240 250 260 270 280 80 90 100 110 120 130 pF1KE0 KNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFR--KSPSSTW- . .. ... . .: .: : ...:: ...::: . . :. . .: CCDS48 RAVRTMQNLFPEE---------------YNFYPRSWILPDEFQLFVAQVQMVKDDDPSWK 290 300 310 320 330 140 150 160 170 180 190 pF1KE0 ---IMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGG :.:: : :: ::.::. :.:. ... ... :.. :: .:::: CCDS48 PTFIVKPDGGCQGDGIYLIKDPSDIR----------LAGTLQSRPAVVQEYICKPLLIDK 340 350 360 370 380 200 210 220 230 240 250 pF1KE0 RKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYT-PSTSELDNMFVHLTNVAIQKHGED :::.:::::... ::. :. : :. :::: : :. ..: .:.:::: ... :. . CCDS48 LKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGN 390 400 410 420 430 440 260 270 280 290 300 pF1KE0 YNHIH----GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMN----ND . : :.: : :.. : :..: .. .:....: ...... :..: .. .: CCDS48 FIHSDSASTGSKRTFSSILCRL-SSKGVDI-KKVWSDIISVVIKTVIALTPELKVFYQSD 450 460 470 480 490 500 310 320 330 340 350 pF1KE0 -------KHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDR---ILKY--NLINDT ::. :.::.. .::: :.::::.::. .. ... .:... CCDS48 IPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEE 510 520 530 540 550 560 360 370 380 390 400 410 pF1KE0 LNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELA-QGDGADRELRSRQGQSLGPRAGR ...:: : : .: :. : .. .: . :. : :: : . .:.: CCDS48 VKVAV----IRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHL 570 580 590 600 610 420 pF1KE0 SRDSGRAVLTTWK CCDS48 PSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSL 620 630 640 650 660 670 >>CCDS32124.1 TTLL5 gene_id:23093|Hs108|chr14 (1281 aa) initn: 609 init1: 262 opt: 295 Z-score: 359.8 bits: 77.2 E(32554): 1e-13 Smith-Waterman score: 626; 35.7% identity (64.0% similar) in 336 aa overlap (33-354:95-394) 10 20 30 40 50 60 pF1KE0 GKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIV :.:..: . . . : ... ::. : : CCDS32 LSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHL--KPFLLRT---LSEAQKV 70 80 90 100 110 70 80 90 100 110 120 pF1KE0 NHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNL :::: ::::::: . ::: :... .: . . ..: :..:::.: CCDS32 NHFPRSYELTRKDRLYKNIIRMQHT-------------HG-FKAFHILPQTFLLPAEYAE 120 130 140 150 160 130 140 150 160 170 180 pF1KE0 FVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISL : . . :. . ::.:: ....:.:..:::. .:: : .: ..: CCDS32 FCNSYSKD-RGPWIVKPVASSRGRGVYLINNPNQI---------------SLEENILVSR 170 180 190 200 190 200 210 220 230 240 pF1KE0 YINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTN :::::::: :::.::::::..: :: :.:. :. :: ::.: ..... :.:.:::: CCDS32 YINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTN 210 220 230 240 250 260 250 260 270 280 290 pF1KE0 VAIQKHGEDYNHI-------HGGKWTVSNLRLYLESTRGKEVTS---KLFDEIHWIIVQS ...:.. :: .:.::..: . ::.. .:...:. .. : : :... CCDS32 YSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQ-EGRDTTALMAHVEDLIIKTIISA 270 280 290 300 310 320 300 310 320 330 340 pF1KE0 LKAVAPV----MNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLI :.: . . . . ::: ::.:..::. :::::.::: ::::. .. : .: ..: CCDS32 ELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMI 330 340 350 360 370 380 350 360 370 380 390 400 pF1KE0 NDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRA .: ... CCDS32 SDMFTVVGFVCQDPAQRASTRPIYPTFESSRRNPFQKPQRCRPLSASDAEMKNLVGSARE 390 400 410 420 430 440 423 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:00:45 2016 done: Thu Nov 3 00:00:45 2016 Total Scan time: 2.080 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]