Result of FASTA (omim) for
pF1KE0547
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0547, 423 aa
1>>>pF1KE0547 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5531+/-0.000424; mu= 15.8235+/- 0.026
mean_var=69.0509+/-13.509, 0's: 0 Z-trim(110.8): 43 B-trim: 0 in 0/54
Lambda= 0.154344
statistics sampled from 19194 (19222) to 19194 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.225), width: 16
Scan time: 6.980
The best scores are: opt bits E(85289)
XP_016884241 (OMIM: 608955) PREDICTED: probable tu ( 423) 2864 647.2 2.3e-185
NP_036395 (OMIM: 608955) probable tubulin polyglut ( 423) 2864 647.2 2.3e-185
XP_016884240 (OMIM: 608955) PREDICTED: probable tu ( 423) 2864 647.2 2.3e-185
XP_016884242 (OMIM: 608955) PREDICTED: probable tu ( 385) 2591 586.4 4.3e-167
XP_011528410 (OMIM: 608955) PREDICTED: probable tu ( 385) 2591 586.4 4.3e-167
XP_006724288 (OMIM: 608955) PREDICTED: probable tu ( 326) 2137 485.2 1e-136
XP_011528412 (OMIM: 608955) PREDICTED: probable tu ( 309) 2093 475.4 8.6e-134
NP_714923 (OMIM: 608291) tubulin--tyrosine ligase ( 377) 300 76.2 1.6e-13
XP_005263656 (OMIM: 608291) PREDICTED: tubulin--ty ( 367) 297 75.5 2.4e-13
NP_055887 (OMIM: 612268,615860) tubulin polyglutam (1281) 295 75.3 9.6e-13
XP_016879986 (OMIM: 610849) PREDICTED: tubulin pol ( 560) 276 70.9 8.9e-12
XP_016879981 (OMIM: 610849) PREDICTED: tubulin pol ( 738) 276 71.0 1.1e-11
XP_016879982 (OMIM: 610849) PREDICTED: tubulin pol ( 738) 276 71.0 1.1e-11
XP_016879983 (OMIM: 610849) PREDICTED: tubulin pol ( 738) 276 71.0 1.1e-11
XP_016879980 (OMIM: 610849) PREDICTED: tubulin pol ( 890) 276 71.0 1.3e-11
NP_001124390 (OMIM: 610849) tubulin polyglutamylas ( 891) 276 71.0 1.3e-11
XP_016879985 (OMIM: 610849) PREDICTED: tubulin pol ( 583) 196 53.1 2.1e-06
NP_775894 (OMIM: 610849) tubulin polyglutamylase T ( 584) 196 53.1 2.1e-06
XP_016879984 (OMIM: 610849) PREDICTED: tubulin pol ( 644) 196 53.2 2.3e-06
>>XP_016884241 (OMIM: 608955) PREDICTED: probable tubuli (423 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 3448.7 bits: 647.2 E(85289): 2.3e-185
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KE0 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
370 380 390 400 410 420
pF1KE0 TWK
:::
XP_016 TWK
>>NP_036395 (OMIM: 608955) probable tubulin polyglutamyl (423 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 3448.7 bits: 647.2 E(85289): 2.3e-185
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KE0 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
370 380 390 400 410 420
pF1KE0 TWK
:::
NP_036 TWK
>>XP_016884240 (OMIM: 608955) PREDICTED: probable tubuli (423 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 3448.7 bits: 647.2 E(85289): 2.3e-185
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KE0 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
370 380 390 400 410 420
pF1KE0 TWK
:::
XP_016 TWK
>>XP_016884242 (OMIM: 608955) PREDICTED: probable tubuli (385 aa)
initn: 2591 init1: 2591 opt: 2591 Z-score: 3120.8 bits: 586.4 E(85289): 4.3e-167
Smith-Waterman score: 2591; 100.0% identity (100.0% similar) in 385 aa overlap (39-423:1-385)
10 20 30 40 50 60
pF1KE0 TDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNH
::::::::::::::::::::::::::::::
XP_016 MSVQTIRNVFSVEAGYRLSDDQIVNHFPNH
10 20 30
70 80 90 100 110 120
pF1KE0 YELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 KSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 LIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 GEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 SPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
340 350 360 370 380
>>XP_011528410 (OMIM: 608955) PREDICTED: probable tubuli (385 aa)
initn: 2591 init1: 2591 opt: 2591 Z-score: 3120.8 bits: 586.4 E(85289): 4.3e-167
Smith-Waterman score: 2591; 100.0% identity (100.0% similar) in 385 aa overlap (39-423:1-385)
10 20 30 40 50 60
pF1KE0 TDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNH
::::::::::::::::::::::::::::::
XP_011 MSVQTIRNVFSVEAGYRLSDDQIVNHFPNH
10 20 30
70 80 90 100 110 120
pF1KE0 YELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 KSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 LIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 GEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 SPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
340 350 360 370 380
>>XP_006724288 (OMIM: 608955) PREDICTED: probable tubuli (326 aa)
initn: 2136 init1: 2136 opt: 2137 Z-score: 2575.6 bits: 485.2 E(85289): 1e-136
Smith-Waterman score: 2137; 97.5% identity (98.8% similar) in 326 aa overlap (98-423:2-326)
70 80 90 100 110 120
pF1KE0 HYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEF
: :: . ... :::::::::::::::::::
XP_006 MKMENTS-IWVYFVPVTYMLPADYNLFVEEF
10 20 30
130 140 150 160 170 180
pF1KE0 RKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNP
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE0 LLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 HGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCF
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 ECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWN
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 KSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
280 290 300 310 320
>>XP_011528412 (OMIM: 608955) PREDICTED: probable tubuli (309 aa)
initn: 2093 init1: 2093 opt: 2093 Z-score: 2523.0 bits: 475.4 E(85289): 8.6e-134
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 309 aa overlap (115-423:1-309)
90 100 110 120 130 140
pF1KE0 RKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQ
::::::::::::::::::::::::::::::
XP_011 MLPADYNLFVEEFRKSPSSTWIMKPCGKAQ
10 20 30
150 160 170 180 190 200
pF1KE0 GKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVS
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE0 TYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSN
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE0 LRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE0 IEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDE
220 230 240 250 260 270
390 400 410 420
pF1KE0 ELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
:::::::::::::::::::::::::::::::::::::::
XP_011 ELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
280 290 300
>>NP_714923 (OMIM: 608291) tubulin--tyrosine ligase [Hom (377 aa)
initn: 243 init1: 63 opt: 300 Z-score: 364.0 bits: 76.2 E(85289): 1.6e-13
Smith-Waterman score: 300; 25.8% identity (58.3% similar) in 333 aa overlap (60-371:60-371)
30 40 50 60 70 80
pF1KE0 ENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELE
:.::.. . .: :: .:: :: ::
NP_714 LRRDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKT-SPELA
30 40 50 60 70 80
90 100 110 120 130
pF1KE0 KEGS---------PLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEF-RKSPS---STWI
. . : : . :.. . ..:. . ::. . ..::
NP_714 ESCTWFPESYVIYPTNLKTPVAPAQNGIQPPISNSRTDEREFFLASYNRKKEDGEGNVWI
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE0 MKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLI--GGRK
: . :.:.::.. .. :.. .:...... ..::. :...:::. : ::
NP_714 AKSSAGAKGEGILISSEASEL---------LDFIDNQGQ-VHVIQKYLEHPLLLEPGHRK
150 160 170 180 190
200 210 220 230 240 250
pF1KE0 FDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQK-HGEDYN
::.: .:::. . :.:. : : . : ...... :::: ::: ....:.
NP_714 FDIRSWVLVDHQYNI--YLYREGVLRTASEPY--HVDNFQDKTCHLTNHCIQKEYSKNYG
200 210 220 230 240 250
260 270 280 290 300
pF1KE0 HIH-GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH----CFE
. . :.. ... :: :. . . :... .:. :: . : .: :.... :: :.
NP_714 KYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAIST-KHLPYQSFQ
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE0 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK
.:.:...:..:: ::::::..:. ... . : .... ... . : :: . .
NP_714 LFGFDFMVDEELKVWLIEVNGAPACAQKLYAE--LCQGIVDIAISSVFPP---PDVEQPQ
320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
. :
NP_714 TQPAAFIKL
370
>>XP_005263656 (OMIM: 608291) PREDICTED: tubulin--tyrosi (367 aa)
initn: 246 init1: 66 opt: 297 Z-score: 360.5 bits: 75.5 E(85289): 2.4e-13
Smith-Waterman score: 297; 28.5% identity (59.4% similar) in 298 aa overlap (60-336:60-341)
30 40 50 60 70 80
pF1KE0 ENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELE
:.::.. . .: :: .:: :: ::
XP_005 LRRDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKT-SPELA
30 40 50 60 70 80
90 100 110 120 130
pF1KE0 KEGS---------PLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEF-RKSPS---STWI
. . : : . :.. . ..:. . ::. . ..::
XP_005 ESCTWFPESYVIYPTNLKTPVAPAQNGIQPPISNSRTDEREFFLASYNRKKEDGEGNVWI
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE0 MKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLI--GGRK
: . :.:.:: ::. :. :. .:...... ..::. :...:::. : ::
XP_005 AKSSAGAKGEGI-LIS--------SEASELLDFIDNQGQ-VHVIQKYLEHPLLLEPGHRK
150 160 170 180 190
200 210 220 230 240 250
pF1KE0 FDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQK-HGEDYN
::.: .:::. . :.:. : : . : ...... :::: ::: ....:.
XP_005 FDIRSWVLVDHQYNI--YLYREGVLRTASEPY--HVDNFQDKTCHLTNHCIQKEYSKNYG
200 210 220 230 240 250
260 270 280 290 300
pF1KE0 HIH-GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH----CFE
. . :.. ... :: :. . . :... .:. :: . : .: :.... :: :.
XP_005 KYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAIST-KHLPYQSFQ
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE0 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNK
.:.:...:..:: ::::::..:. ..:
XP_005 LFGFDFMVDEELKVWLIEVNGAPACAQSGRCPEEQKLLRTCSPELLLLSGEGWL
320 330 340 350 360
>>NP_055887 (OMIM: 612268,615860) tubulin polyglutamylas (1281 aa)
initn: 609 init1: 262 opt: 295 Z-score: 349.8 bits: 75.3 E(85289): 9.6e-13
Smith-Waterman score: 626; 35.7% identity (64.0% similar) in 336 aa overlap (33-354:95-394)
10 20 30 40 50 60
pF1KE0 GKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIV
:.:..: . . . : ... ::. : :
NP_055 LSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHL--KPFLLRT---LSEAQKV
70 80 90 100 110
70 80 90 100 110 120
pF1KE0 NHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNL
:::: ::::::: . ::: :... .: . . ..: :..:::.:
NP_055 NHFPRSYELTRKDRLYKNIIRMQHT-------------HG-FKAFHILPQTFLLPAEYAE
120 130 140 150 160
130 140 150 160 170 180
pF1KE0 FVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISL
: . . :. . ::.:: ....:.:..:::. .:: : .: ..:
NP_055 FCNSYSKD-RGPWIVKPVASSRGRGVYLINNPNQI---------------SLEENILVSR
170 180 190 200
190 200 210 220 230 240
pF1KE0 YINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTN
:::::::: :::.::::::..: :: :.:. :. :: ::.: ..... :.:.::::
NP_055 YINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTN
210 220 230 240 250 260
250 260 270 280 290
pF1KE0 VAIQKHGEDYNHI-------HGGKWTVSNLRLYLESTRGKEVTS---KLFDEIHWIIVQS
...:.. :: .:.::..: . ::.. .:...:. .. : : :...
NP_055 YSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQ-EGRDTTALMAHVEDLIIKTIISA
270 280 290 300 310 320
300 310 320 330 340
pF1KE0 LKAVAPV----MNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLI
:.: . . . . ::: ::.:..::. :::::.::: ::::. .. : .: ..:
NP_055 ELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMI
330 340 350 360 370 380
350 360 370 380 390 400
pF1KE0 NDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRA
.: ...
NP_055 SDMFTVVGFVCQDPAQRASTRPIYPTFESSRRNPFQKPQRCRPLSASDAEMKNLVGSARE
390 400 410 420 430 440
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:00:45 2016 done: Thu Nov 3 00:00:47 2016
Total Scan time: 6.980 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]