FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0549, 154 aa 1>>>pF1KE0549 154 - 154 aa - 154 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1341+/-0.000607; mu= 13.6053+/- 0.037 mean_var=69.0881+/-13.532, 0's: 0 Z-trim(111.7): 63 B-trim: 0 in 0/52 Lambda= 0.154302 statistics sampled from 12535 (12600) to 12535 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.387), width: 16 Scan time: 1.630 The best scores are: opt bits E(32554) CCDS13790.1 UBE2L3 gene_id:7332|Hs108|chr22 ( 154) 1056 243.0 5.4e-65 CCDS58795.1 UBE2L3 gene_id:7332|Hs108|chr22 ( 212) 1006 232.0 1.5e-61 CCDS58796.1 UBE2L3 gene_id:7332|Hs108|chr22 ( 122) 787 183.1 4.7e-47 CCDS7960.1 UBE2L6 gene_id:9246|Hs108|chr11 ( 153) 594 140.2 4.9e-34 CCDS5474.1 UBE2D4 gene_id:51619|Hs108|chr7 ( 147) 410 99.2 1e-21 CCDS7252.1 UBE2D1 gene_id:7321|Hs108|chr10 ( 147) 404 97.9 2.5e-21 CCDS43369.1 UBE2D2 gene_id:7322|Hs108|chr5 ( 147) 399 96.8 5.5e-21 CCDS3661.1 UBE2D3 gene_id:7323|Hs108|chr4 ( 148) 393 95.4 1.4e-20 CCDS3660.1 UBE2D3 gene_id:7323|Hs108|chr4 ( 147) 391 95.0 1.9e-20 CCDS47275.1 UBE2D2 gene_id:7322|Hs108|chr5 ( 118) 387 94.0 2.9e-20 CCDS3659.1 UBE2D3 gene_id:7323|Hs108|chr4 ( 149) 387 94.1 3.5e-20 CCDS75172.1 UBE2D3 gene_id:7323|Hs108|chr4 ( 118) 381 92.7 7.4e-20 CCDS73139.1 UBE2D1 gene_id:7321|Hs108|chr10 ( 109) 368 89.8 5.2e-19 CCDS7961.1 UBE2L6 gene_id:9246|Hs108|chr11 ( 87) 348 85.2 9.5e-18 CCDS1425.1 UBE2T gene_id:29089|Hs108|chr1 ( 197) 347 85.3 2.1e-17 CCDS2638.1 UBE2E1 gene_id:7324|Hs108|chr3 ( 193) 337 83.0 9.7e-17 CCDS2637.1 UBE2E2 gene_id:7325|Hs108|chr3 ( 201) 337 83.1 1e-16 CCDS2282.1 UBE2E3 gene_id:10477|Hs108|chr2 ( 207) 337 83.1 1e-16 CCDS31875.1 UBE2N gene_id:7334|Hs108|chr12 ( 152) 333 82.1 1.5e-16 CCDS56244.1 UBE2E1 gene_id:7324|Hs108|chr3 ( 160) 332 81.9 1.8e-16 CCDS2639.1 UBE2E1 gene_id:7324|Hs108|chr3 ( 176) 330 81.5 2.7e-16 CCDS14580.1 UBE2A gene_id:7319|Hs108|chrX ( 152) 308 76.5 7.1e-15 CCDS4174.1 UBE2B gene_id:7320|Hs108|chr5 ( 152) 303 75.4 1.5e-14 CCDS33976.1 UBE2K gene_id:3093|Hs108|chr4 ( 200) 296 73.9 5.6e-14 CCDS12987.1 UBE2M gene_id:9040|Hs108|chr19 ( 183) 293 73.2 8.3e-14 CCDS78500.1 UBE2A gene_id:7319|Hs108|chrX ( 119) 279 70.0 5.1e-13 CCDS47043.1 UBE2K gene_id:3093|Hs108|chr4 ( 157) 273 68.7 1.6e-12 CCDS5814.1 UBE2H gene_id:7328|Hs108|chr7 ( 183) 264 66.8 7.3e-12 CCDS10433.1 UBE2I gene_id:7329|Hs108|chr16 ( 158) 256 64.9 2.2e-11 CCDS6546.1 UBE2R2 gene_id:54926|Hs108|chr9 ( 238) 251 64.0 6.7e-11 CCDS32532.1 UBE2G1 gene_id:7326|Hs108|chr17 ( 170) 249 63.4 7e-11 >>CCDS13790.1 UBE2L3 gene_id:7332|Hs108|chr22 (154 aa) initn: 1056 init1: 1056 opt: 1056 Z-score: 1280.4 bits: 243.0 E(32554): 5.4e-65 Smith-Waterman score: 1056; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154) 10 20 30 40 50 60 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP 70 80 90 100 110 120 130 140 150 pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :::::::::::::::::::::::::::::::::: CCDS13 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD 130 140 150 >>CCDS58795.1 UBE2L3 gene_id:7332|Hs108|chr22 (212 aa) initn: 1003 init1: 1003 opt: 1006 Z-score: 1218.3 bits: 232.0 E(32554): 1.5e-61 Smith-Waterman score: 1006; 94.9% identity (96.8% similar) in 156 aa overlap (1-154:57-212) 10 20 pF1KE0 MAASRRLM--KELEEIRKCGMKNFRNIQVD .:. :: .::::::::::::::::::: CCDS58 VLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVD 30 40 50 60 70 80 30 40 50 60 70 80 pF1KE0 EANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLP 90 100 110 120 130 140 90 100 110 120 130 140 pF1KE0 VISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG 150 160 170 180 190 200 150 pF1KE0 EKRPVD :::::: CCDS58 EKRPVD 210 >>CCDS58796.1 UBE2L3 gene_id:7332|Hs108|chr22 (122 aa) initn: 787 init1: 787 opt: 787 Z-score: 958.2 bits: 183.1 E(32554): 4.7e-47 Smith-Waterman score: 787; 97.4% identity (99.1% similar) in 116 aa overlap (39-154:7-122) 10 20 30 40 50 60 pF1KE0 KELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKI .. ::::::::::::::::::::::::::: CCDS58 MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKI 10 20 30 70 80 90 100 110 120 pF1KE0 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE 40 50 60 70 80 90 130 140 150 pF1KE0 YSKDRKKFCKNAEEFTKKYGEKRPVD :::::::::::::::::::::::::: CCDS58 YSKDRKKFCKNAEEFTKKYGEKRPVD 100 110 120 >>CCDS7960.1 UBE2L6 gene_id:9246|Hs108|chr11 (153 aa) initn: 594 init1: 594 opt: 594 Z-score: 724.6 bits: 140.2 E(32554): 4.9e-34 Smith-Waterman score: 594; 55.3% identity (80.3% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE : :: :..::::...: .::.. :.::.:.:..:..::.::: :: ..:.:: : CCDS79 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP :::::: : : :::::::.::.::.:::.::.::::: ::: ::...: .::: :. ..: CCDS79 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP 70 80 90 100 110 120 130 140 150 pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :: :::. ... . : ::::::: ..: :: CCDS79 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS 130 140 150 >>CCDS5474.1 UBE2D4 gene_id:51619|Hs108|chr7 (147 aa) initn: 391 init1: 232 opt: 410 Z-score: 503.5 bits: 99.2 E(32554): 1e-21 Smith-Waterman score: 410; 39.7% identity (74.7% similar) in 146 aa overlap (3-147:2-145) 10 20 30 40 50 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA : .:..::: .... . : . .:. ::. :. :.. ::. :.: . :.::. CCDS54 MALKRIQKELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPT 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH .:::::::..: ::::::::. .:..:: .. .. :.:: ...:. :. .:. ::.:. CCDS54 DYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQ-WSPALTVSKVLLSICSLLCDPNPDD 60 70 80 90 100 110 120 130 140 150 pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :: ..:. :. ::.:. . :.:.:.:: CCDS54 PLVPEIAHTYKADREKYNRLAREWTQKYAM 120 130 140 >>CCDS7252.1 UBE2D1 gene_id:7321|Hs108|chr10 (147 aa) initn: 358 init1: 184 opt: 404 Z-score: 496.3 bits: 97.9 E(32554): 2.5e-21 Smith-Waterman score: 404; 39.0% identity (74.7% similar) in 146 aa overlap (3-147:2-145) 10 20 30 40 50 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA : .:..::: .... . : . .:. ::. :. : . :. :.: . ..::. CCDS72 MALKRIQKELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPT 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH .::::::::.: ::::::::. .:..:: .. .. :.:: ...:. :. .:. ::.:. CCDS72 DYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQ-WSPALTVSKVLLSICSLLCDPNPDD 60 70 80 90 100 110 120 130 140 150 pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :: :.:. :..:..:. ..:.:.:.:: CCDS72 PLVPDIAQIYKSDKEKYNRHAREWTQKYAM 120 130 140 >>CCDS43369.1 UBE2D2 gene_id:7322|Hs108|chr5 (147 aa) initn: 385 init1: 229 opt: 399 Z-score: 490.2 bits: 96.8 E(32554): 5.5e-21 Smith-Waterman score: 399; 38.4% identity (73.3% similar) in 146 aa overlap (3-147:2-145) 10 20 30 40 50 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA : .:. :::... . . : . ... ::. :. :.. ::. :.: . :.::. CCDS43 MALKRIHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH .:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:. CCDS43 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD 60 70 80 90 100 110 120 130 140 150 pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :: ..:. :. ::.:. . :.:.:.:: CCDS43 PLVPEIARIYKTDREKYNRIAREWTQKYAM 120 130 140 >>CCDS3661.1 UBE2D3 gene_id:7323|Hs108|chr4 (148 aa) initn: 381 init1: 229 opt: 393 Z-score: 483.0 bits: 95.4 E(32554): 1.4e-20 Smith-Waterman score: 393; 38.4% identity (71.9% similar) in 146 aa overlap (3-147:2-145) 10 20 30 40 50 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA : .:. ::: .. . . : . ... ::. :. :.. ::. :.: . :.::. CCDS36 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH .:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:. CCDS36 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD 60 70 80 90 100 110 120 130 140 150 pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :: ..:. :. :: :. . :.:.:.:: CCDS36 PLVPEIARIYKTDRDKYNRLAREWTEKYAML 120 130 140 >>CCDS3660.1 UBE2D3 gene_id:7323|Hs108|chr4 (147 aa) initn: 379 init1: 229 opt: 391 Z-score: 480.6 bits: 95.0 E(32554): 1.9e-20 Smith-Waterman score: 391; 37.7% identity (71.9% similar) in 146 aa overlap (3-147:2-145) 10 20 30 40 50 pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA : .:. ::: .. . . : . ... ::. :. :.. ::. :.: . :.::. CCDS36 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH .:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:. CCDS36 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD 60 70 80 90 100 110 120 130 140 150 pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD :: ..:. :. :: :. . ..:.:.:: CCDS36 PLVPEIARIYKTDRDKYNRISREWTQKYAM 120 130 140 >>CCDS47275.1 UBE2D2 gene_id:7322|Hs108|chr5 (118 aa) initn: 372 init1: 216 opt: 387 Z-score: 477.2 bits: 94.0 E(32554): 2.9e-20 Smith-Waterman score: 387; 42.7% identity (78.6% similar) in 117 aa overlap (32-147:1-116) 10 20 30 40 50 60 pF1KE0 AASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAE .. ::. :. :.. ::. :.: . :.::.. CCDS47 MFHWQATIMGPNDSPYQGGVFFLTIHFPTD 10 20 30 70 80 90 100 110 120 pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP :::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:. : CCDS47 YPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDDP 40 50 60 70 80 130 140 150 pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD : ..:. :. ::.:. . :.:.:.:: CCDS47 LVPEIARIYKTDREKYNRIAREWTQKYAM 90 100 110 154 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:56:08 2016 done: Wed Nov 2 23:56:08 2016 Total Scan time: 1.630 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]