FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0550, 307 aa 1>>>pF1KE0550 307 - 307 aa - 307 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8110+/-0.000345; mu= 13.0665+/- 0.022 mean_var=72.2112+/-14.345, 0's: 0 Z-trim(114.5): 16 B-trim: 0 in 0/55 Lambda= 0.150929 statistics sampled from 24355 (24369) to 24355 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.286), width: 16 Scan time: 6.760 The best scores are: opt bits E(85289) NP_005650 (OMIM: 601754) ubiquitin fusion degradat ( 307) 2073 460.5 2e-129 XP_011528663 (OMIM: 601754) PREDICTED: ubiquitin f ( 302) 2038 452.8 3.8e-127 NP_001030324 (OMIM: 601754) ubiquitin fusion degra ( 266) 1807 402.5 4.7e-112 >>NP_005650 (OMIM: 601754) ubiquitin fusion degradation (307 aa) initn: 2073 init1: 2073 opt: 2073 Z-score: 2444.7 bits: 460.5 E(85289): 2e-129 Smith-Waterman score: 2073; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KE0 MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFVAFSGEGQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFVAFSGEGQSL 250 260 270 280 290 300 pF1KE0 RKKGRKP ::::::: NP_005 RKKGRKP >>XP_011528663 (OMIM: 601754) PREDICTED: ubiquitin fusio (302 aa) initn: 2038 init1: 2038 opt: 2038 Z-score: 2403.6 bits: 452.8 E(85289): 3.8e-127 Smith-Waterman score: 2038; 100.0% identity (100.0% similar) in 302 aa overlap (6-307:1-302) 10 20 30 40 50 60 pF1KE0 MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLN ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLN 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 ITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 TYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 SIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 GVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFVAFSGEGQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFVAFSGEGQSL 240 250 260 270 280 290 pF1KE0 RKKGRKP ::::::: XP_011 RKKGRKP 300 >>NP_001030324 (OMIM: 601754) ubiquitin fusion degradati (266 aa) initn: 1807 init1: 1807 opt: 1807 Z-score: 2132.7 bits: 402.5 E(85289): 4.7e-112 Smith-Waterman score: 1807; 100.0% identity (100.0% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KE0 MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFVAFSGEGQSL :::::::::::::::::::::::::: NP_001 GVEPSPSPIKPGDIKRGIPNYEFKLG 250 260 307 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:52:48 2016 done: Wed Nov 2 23:52:49 2016 Total Scan time: 6.760 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]