FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0552, 302 aa 1>>>pF1KE0552 302 - 302 aa - 302 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4137+/-0.00076; mu= 15.6719+/- 0.046 mean_var=71.0550+/-14.586, 0's: 0 Z-trim(109.5): 7 B-trim: 515 in 1/52 Lambda= 0.152152 statistics sampled from 10908 (10913) to 10908 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.335), width: 16 Scan time: 2.440 The best scores are: opt bits E(32554) CCDS46723.1 MPPED1 gene_id:758|Hs108|chr22 ( 326) 2126 475.4 2.6e-134 CCDS7870.1 MPPED2 gene_id:744|Hs108|chr11 ( 294) 1727 387.7 5.5e-108 CCDS44560.1 MPPED2 gene_id:744|Hs108|chr11 ( 277) 1519 342.1 2.9e-94 >>CCDS46723.1 MPPED1 gene_id:758|Hs108|chr22 (326 aa) initn: 2126 init1: 2126 opt: 2126 Z-score: 2524.9 bits: 475.4 E(32554): 2.6e-134 Smith-Waterman score: 2126; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:25-326) 10 20 30 pF1KE0 MAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTF :::::::::::::::::::::::::::::::::::: CCDS46 MWRSRWDASVLKAEALALLPCGLGMAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 YNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 ELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPEN 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 YENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVD 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 ILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYV 250 260 270 280 290 300 280 290 300 pF1KE0 NASVCTVNYQPVNPPIVIDLPTPRNS :::::::::::::::::::::::::: CCDS46 NASVCTVNYQPVNPPIVIDLPTPRNS 310 320 >>CCDS7870.1 MPPED2 gene_id:744|Hs108|chr11 (294 aa) initn: 1748 init1: 1727 opt: 1727 Z-score: 2052.2 bits: 387.7 E(32554): 5.5e-108 Smith-Waterman score: 1727; 79.3% identity (94.6% similar) in 294 aa overlap (9-302:1-294) 10 20 30 40 50 60 pF1KE0 MAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAP :: ..... : ::::::::::::: :::::.:::::::.::::.:.:.: CCDS78 MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTP 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 KPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKI :: :.:::::.:::::::: :::::::.:.:.::::::::::::::::.:::.::::::: CCDS78 KPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 VIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGF :::::::::::.::::::.:::.: ::::::::::...:::::::: ::::::::::.:: CCDS78 VIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 RIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGC ::::.:: ::: ::::::::::.::.::::::::.:::.:::::::: :::::..::::: CCDS78 RIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGC 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 VELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPR :::::::::::.:.::::: ::::::.:.:: :::.:::.:::..::.::::..:::.:. CCDS78 VELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQ 240 250 260 270 280 290 pF1KE0 NS .: CCDS78 GS >>CCDS44560.1 MPPED2 gene_id:744|Hs108|chr11 (277 aa) initn: 1519 init1: 1519 opt: 1519 Z-score: 1805.8 bits: 342.1 E(32554): 2.9e-94 Smith-Waterman score: 1519; 81.2% identity (94.1% similar) in 255 aa overlap (9-263:1-255) 10 20 30 40 50 60 pF1KE0 MAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAP :: ..... : ::::::::::::: :::::.:::::::.::::.:.:.: CCDS44 MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTP 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 KPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKI :: :.:::::.:::::::: :::::::.:.:.::::::::::::::::.:::.::::::: CCDS44 KPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 VIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGF :::::::::::.::::::.:::.: ::::::::::...:::::::: ::::::::::.:: CCDS44 VIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 RIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGC ::::.:: ::: ::::::::::.::.::::::::.:::.:::::::: :::::..::::: CCDS44 RIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGC 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 VELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPR :::::::::::.:.::::: ::: CCDS44 VELLNTVQRRVRPKLHVFGGIHEVNPVSISKALRTKICSLPSKTS 240 250 260 270 302 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:46:35 2016 done: Wed Nov 2 23:46:35 2016 Total Scan time: 2.440 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]