FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0561, 333 aa 1>>>pF1KE0561 333 - 333 aa - 333 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0023+/-0.000375; mu= 17.4856+/- 0.023 mean_var=63.4075+/-13.311, 0's: 0 Z-trim(112.1): 19 B-trim: 531 in 1/54 Lambda= 0.161066 statistics sampled from 20858 (20877) to 20858 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.245), width: 16 Scan time: 5.670 The best scores are: opt bits E(85289) NP_001002254 (OMIM: 300925) acyl-CoA wax alcohol a ( 333) 2311 545.8 4.7e-155 XP_011529178 (OMIM: 300925) PREDICTED: acyl-CoA wa ( 333) 2311 545.8 4.7e-155 NP_940914 (OMIM: 300926) diacylglycerol O-acyltran ( 337) 1252 299.7 5.6e-81 NP_001013597 (OMIM: 300924) acyl-CoA wax alcohol a ( 328) 1222 292.8 6.9e-79 XP_011543606 (OMIM: 606983) PREDICTED: diacylglyce ( 358) 1194 286.3 6.8e-77 NP_115953 (OMIM: 606983) diacylglycerol O-acyltran ( 388) 1194 286.3 7.2e-77 NP_001240820 (OMIM: 606983) diacylglycerol O-acylt ( 345) 1149 275.8 9.2e-74 NP_835470 (OMIM: 610184) 2-acylglycerol O-acyltran ( 341) 1020 245.8 9.6e-65 XP_016884784 (OMIM: 300924) PREDICTED: acyl-CoA wa ( 395) 975 235.4 1.5e-61 NP_079374 (OMIM: 610270) 2-acylglycerol O-acyltran ( 334) 956 231.0 2.8e-60 NP_477513 (OMIM: 610268) 2-acylglycerol O-acyltran ( 335) 956 231.0 2.8e-60 XP_011514428 (OMIM: 610184) PREDICTED: 2-acylglyce ( 305) 896 217.0 4.2e-56 XP_005250366 (OMIM: 610184) PREDICTED: 2-acylglyce ( 344) 876 212.4 1.1e-54 XP_011543569 (OMIM: 610270) PREDICTED: 2-acylglyce ( 336) 841 204.2 3.2e-52 XP_011514429 (OMIM: 610184) PREDICTED: 2-acylglyce ( 223) 724 176.9 3.5e-44 NP_001274076 (OMIM: 610184) 2-acylglycerol O-acylt ( 281) 667 163.8 4.1e-40 >>NP_001002254 (OMIM: 300925) acyl-CoA wax alcohol acylt (333 aa) initn: 2311 init1: 2311 opt: 2311 Z-score: 2904.7 bits: 545.8 E(85289): 4.7e-155 Smith-Waterman score: 2311; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV 250 260 270 280 290 300 310 320 330 pF1KE0 AKYHTLYIDALRKLFDQHKTKFGISETQELEII ::::::::::::::::::::::::::::::::: NP_001 AKYHTLYIDALRKLFDQHKTKFGISETQELEII 310 320 330 >>XP_011529178 (OMIM: 300925) PREDICTED: acyl-CoA wax al (333 aa) initn: 2311 init1: 2311 opt: 2311 Z-score: 2904.7 bits: 545.8 E(85289): 4.7e-155 Smith-Waterman score: 2311; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV 250 260 270 280 290 300 310 320 330 pF1KE0 AKYHTLYIDALRKLFDQHKTKFGISETQELEII ::::::::::::::::::::::::::::::::: XP_011 AKYHTLYIDALRKLFDQHKTKFGISETQELEII 310 320 330 >>NP_940914 (OMIM: 300926) diacylglycerol O-acyltransfer (337 aa) initn: 1275 init1: 884 opt: 1252 Z-score: 1574.7 bits: 299.7 E(85289): 5.6e-81 Smith-Waterman score: 1252; 50.9% identity (81.2% similar) in 336 aa overlap (1-332:1-336) 10 20 30 40 50 60 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW : . :. .:. .:..: :.:: ... . : . :...:. .::..:: :.::..:: NP_940 MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF .: ..:::: . ::.: :::.. .:::.::.::::. :..:::.. ::::... : : .: NP_940 NTHSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV ::::.:...:::.:::.. :: .::.:..:::::: :.: :: :.. .:::.::.:: : NP_940 ATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG ..:.:: :: ::.::: ::.:.:::.:::: :. :.:.:.:::.....:. : : NP_940 VIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGT 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 FVNRFQKWFQS----MVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPS .. ::: ::. .. . :.:.:::::..:::.::..::.::.::::::.:.:. :. NP_940 WLRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPN 250 260 270 280 290 300 300 310 320 330 pF1KE0 QEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII :. : :::.:::.::::::::::...:. ::::: : NP_940 QKTVDKYHALYISALRKLFDQHKVEYGLPETQELTIT 310 320 330 >>NP_001013597 (OMIM: 300924) acyl-CoA wax alcohol acylt (328 aa) initn: 1202 init1: 643 opt: 1222 Z-score: 1537.2 bits: 292.8 E(85289): 6.9e-79 Smith-Waterman score: 1222; 54.3% identity (81.5% similar) in 313 aa overlap (18-330:15-325) 10 20 30 40 50 60 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW ..:: .: : : . . .::. :: ::. :: ..:: .:: NP_001 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLL-FTSLWPLPVLYFAWLFLDW 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF :::.::::: . ::.: .: : ::::. .:::.:. : .::.. :::::.. : : .: NP_001 KTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV :::.:::: ::::::.. ::. :: .::.:::.:. :.::::. .:..::.: ::::.: NP_001 CTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-GTGNLV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG .:.::..: :.:...::.:..:.:::: :::::. :.:...::::..::: .: . NP_001 GIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV . .::. :. . .: :.:::..: ..: ::::::::..:.::::::.:.::.::::.: NP_001 RMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMV 240 250 260 270 280 290 310 320 330 pF1KE0 AKYHTLYIDALRKLFDQHKTKFGISETQELEII :::.::.:::.::::::::..: ::::.: NP_001 DKYHALYMDALHKLFDQHKTHYGCSETQKLFFL 300 310 320 >>XP_011543606 (OMIM: 606983) PREDICTED: diacylglycerol (358 aa) initn: 1113 init1: 828 opt: 1194 Z-score: 1501.5 bits: 286.3 E(85289): 6.8e-77 Smith-Waterman score: 1194; 48.9% identity (79.9% similar) in 329 aa overlap (5-332:30-357) 10 20 30 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAV ... .. :.:..:.:: .: :.. .. :. XP_011 MDSVKGSPVTGTGSSILSALQDLFSVTWLNRSKVEKQLQVISVLQWVLSFLVLGVACSAI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 NLYLVVFTPYWPVTVLILTWLAFDWKTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHD .: . : : ..:: .:::.:::.::..:::: ::.: .:... ::::..:.:::. XP_011 LMY-IFCTDCWLIAVLYFTWLVFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHN 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 ICPSRNYILVCHPHGLFAHGWFGHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYVM . .::::. ::::... : : .:.:::. :: :::: ::. ::.. : :: ::::.: XP_011 LLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLM 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 STGACSVSRSSIDFLLTHKGTGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQH : : : :::..::.::...:.:: .:.:.:: :: :.::.....:.::.:::..::.: XP_011 SGGICPVSRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRH 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 GVPLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQSMVHIYPCAFYGRG-FTKNSWGLLP :. :.: :.:::...: : :: :.. :: ::... . :: :.::: :....:::.: XP_011 GADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVP 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 YSRPVTTIVGEPLPMPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII ::.:.::.::::. .::.:.:.:. . :::.:..:: ::::.::::::. ::. ::. XP_011 YSKPITTVVGEPITIPKLEHPTQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEVN 300 310 320 330 340 350 >>NP_115953 (OMIM: 606983) diacylglycerol O-acyltransfer (388 aa) initn: 1113 init1: 828 opt: 1194 Z-score: 1501.0 bits: 286.3 E(85289): 7.2e-77 Smith-Waterman score: 1194; 48.9% identity (79.9% similar) in 329 aa overlap (5-332:60-387) 10 20 30 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIA ... .. :.:..:.:: .: :.. .. : NP_115 PALSREGSGRWGTGSSILSALQDLFSVTWLNRSKVEKQLQVISVLQWVLSFLVLGVACSA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VNLYLVVFTPYWPVTVLILTWLAFDWKTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTH . .: . : : ..:: .:::.:::.::..:::: ::.: .:... ::::..:.::: NP_115 ILMY-IFCTDCWLIAVLYFTWLVFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTH 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 DICPSRNYILVCHPHGLFAHGWFGHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYV .. .::::. ::::... : : .:.:::. :: :::: ::. ::.. : :: ::::. NP_115 NLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYL 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 MSTGACSVSRSSIDFLLTHKGTGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQ :: : : :::..::.::...:.:: .:.:.:: :: :.::.....:.::.:::..::. NP_115 MSGGICPVSRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALR 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE0 HGVPLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQSMVHIYPCAFYGRG-FTKNSWGLL ::. :.: :.:::...: : :: :.. :: ::... . :: :.::: :....:::. NP_115 HGADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLV 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE0 PYSRPVTTIVGEPLPMPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII :::.:.::.::::. .::.:.:.:. . :::.:..:: ::::.::::::. ::. ::. NP_115 PYSKPITTVVGEPITIPKLEHPTQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEVN 330 340 350 360 370 380 >>NP_001240820 (OMIM: 606983) diacylglycerol O-acyltrans (345 aa) initn: 1113 init1: 828 opt: 1149 Z-score: 1445.3 bits: 275.8 E(85289): 9.2e-74 Smith-Waterman score: 1149; 51.5% identity (80.8% similar) in 297 aa overlap (37-332:48-344) 10 20 30 40 50 60 pF1KE0 KDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDWKTPQRG :. . : : ..:: .:::.:::.::..: NP_001 AEADRSQRSHGGPALSREGSGRWGVACSAILMYIFCTDCWLIAVLYFTWLVFDWNTPKKG 20 30 40 50 60 70 70 80 90 100 110 120 pF1KE0 GRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHFATEASG ::: ::.: .:... ::::..:.:::.. .::::. ::::... : : .:.:::. NP_001 GRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATE 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE0 FSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMVIVVIGG :: :::: ::. ::.. : :: ::::.:: : : :::..::.::...:.:: .:.:.:: NP_001 VSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNGSGNAIIIVVGG 140 150 160 170 180 190 190 200 210 220 230 240 pF1KE0 LAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGGFVNRFQ :: :.::.....:.::.:::..::.::. :.: :.:::...: : :: :.. : NP_001 AAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPIYSFGENEVYKQVIFEEGSWGRWVQ 200 210 220 230 240 250 250 260 270 280 290 300 pF1KE0 KWFQSMVHIYPCAFYGRG-FTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIVAKYHT : ::... . :: :.::: :....:::.:::.:.::.::::. .::.:.:.:. . ::: NP_001 KKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIPKLEHPTQQDIDLYHT 260 270 280 290 300 310 310 320 330 pF1KE0 LYIDALRKLFDQHKTKFGISETQELEII .:..:: ::::.::::::. ::. ::. NP_001 MYMEALVKLFDKHKTKFGLPETEVLEVN 320 330 340 >>NP_835470 (OMIM: 610184) 2-acylglycerol O-acyltransfer (341 aa) initn: 988 init1: 771 opt: 1020 Z-score: 1283.3 bits: 245.8 E(85289): 9.6e-65 Smith-Waterman score: 1020; 40.9% identity (75.8% similar) in 330 aa overlap (5-333:13-341) 10 20 30 40 50 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLI :: : :.. ...:. .. :.. ... .....:: :: .:. NP_835 MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGP-FFSLLVFVLLFTSLWPFSVFY 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 LTWLAFDWKTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLF :.:: :: ::..:::: .:. .:.. ::.:.::.:: .. :.:::.: ::::.. NP_835 LVWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 AHGWFGHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLT :.. .:.::..:::..:::. :.. .:...:..: :.:.:: : : :::.:.::.:. NP_835 CTGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 HKGTGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYD . :. :....:: : ::.:: :.:..:.::::.::.::. :.:.:.:::.:.. NP_835 QPQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 QHIFTPGGFVNRFQKWFQSMVHIYPCAFYGRG-FTKNSWGLLPYSRPVTTIVGEPLPMPK . :. :.. . : :.... . :: :.::: :. .::::::.. :.::.::.:.:.:. NP_835 LKAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQ 240 250 260 270 280 290 300 310 320 330 pF1KE0 IENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII .:..: : .::.::. ::..::..:: . :. . : .: NP_835 RLHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI 300 310 320 330 340 >>XP_016884784 (OMIM: 300924) PREDICTED: acyl-CoA wax al (395 aa) initn: 1188 init1: 573 opt: 975 Z-score: 1225.9 bits: 235.4 E(85289): 1.5e-61 Smith-Waterman score: 975; 50.4% identity (78.1% similar) in 274 aa overlap (18-291:15-285) 10 20 30 40 50 60 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW ..:: .: : : . . .::. :: ::. :: ..:: .:: XP_016 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLL-FTSLWPLPVLYFAWLFLDW 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF :::.::::: . ::.: .: : ::::. .:::.:. : .::.. :::::.. : : .: XP_016 KTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV :::.:::: ::::::.. ::. :: .::.:::.:. :.::::. .:..::.: ::::.: XP_016 CTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-GTGNLV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG .:.::..: :.:...::.:..:.:::: :::::. :.:...::::..::: .: . XP_016 GIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV . .::. :. . .: :.:::..: ..: ::::::::..: ::: .:. XP_016 RMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVT-VGECHSQPQCHLRFLNLN 240 250 260 270 280 290 310 320 330 pF1KE0 AKYHTLYIDALRKLFDQHKTKFGISETQELEII XP_016 LSLAPPKKRAAEGKVGADLGCESQAQGRRGRLKEEEVLTLSSSLFRSLLAVGEPLPLPQI 300 310 320 330 340 350 >-- initn: 303 init1: 254 opt: 254 Z-score: 320.4 bits: 67.9 E(85289): 4.1e-11 Smith-Waterman score: 254; 75.0% identity (95.8% similar) in 48 aa overlap (283-330:345-392) 260 270 280 290 300 310 pF1KE0 VHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIVAKYHTLYIDALR ::::::.:.::.::::.: :::.::.:::. XP_016 CESQAQGRRGRLKEEEVLTLSSSLFRSLLAVGEPLPLPQIEKPSQEMVDKYHALYMDALH 320 330 340 350 360 370 320 330 pF1KE0 KLFDQHKTKFGISETQELEII ::::::::..: ::::.: XP_016 KLFDQHKTHYGCSETQKLFFL 380 390 >>NP_079374 (OMIM: 610270) 2-acylglycerol O-acyltransfer (334 aa) initn: 929 init1: 929 opt: 956 Z-score: 1203.1 bits: 231.0 E(85289): 2.8e-60 Smith-Waterman score: 956; 42.3% identity (71.9% similar) in 331 aa overlap (1-331:7-332) 10 20 30 40 50 pF1KE0 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILT ...: .. :.: .::.:. :: .: . . .:.. ..:: .: .::: . NP_079 MVEFAPLFMPWERRLQT----LAVLQFVFS-FLALAEICTVGFIALLFTRFWLLTVLYAA 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 WLAFDWKTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAH : .: :..:::.. .: : .::...::::..:.:: .. :::::: ::::..: NP_079 WWYLDRDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GWFGHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHK : :... ::..:::.::::: :... : .: ::.:.:.::.: . . : .:..: NP_079 GAFANLCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GTGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQH : ::.. ...:: : . ::: ::.:.::.::::.:: ::.::.: ..:::.::.:: NP_079 GGGNLLGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 IFTPGGFVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIEN . :... .:. .:... : :.::: . :.::.:: ::.::.::.:. . : . NP_079 PNSSGSWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLH 240 250 260 270 280 290 300 310 320 330 pF1KE0 PSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII ::.: : . : :: : .::. :: ::.: :.:: NP_079 PSEEEVNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC 300 310 320 330 333 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:22:56 2016 done: Wed Nov 2 23:22:57 2016 Total Scan time: 5.670 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]