FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0562, 328 aa 1>>>pF1KE0562 328 - 328 aa - 328 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6868+/-0.000371; mu= 19.6835+/- 0.023 mean_var=63.3934+/-13.046, 0's: 0 Z-trim(113.4): 27 B-trim: 0 in 0/51 Lambda= 0.161084 statistics sampled from 22775 (22794) to 22775 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.267), width: 16 Scan time: 5.710 The best scores are: opt bits E(85289) NP_001013597 (OMIM: 300924) acyl-CoA wax alcohol a ( 328) 2313 546.1 3.7e-155 XP_016884784 (OMIM: 300924) PREDICTED: acyl-CoA wa ( 395) 1965 465.3 9.5e-131 NP_940914 (OMIM: 300926) diacylglycerol O-acyltran ( 337) 1231 294.7 1.9e-79 XP_011529178 (OMIM: 300925) PREDICTED: acyl-CoA wa ( 333) 1222 292.6 7.9e-79 NP_001002254 (OMIM: 300925) acyl-CoA wax alcohol a ( 333) 1222 292.6 7.9e-79 XP_011543606 (OMIM: 606983) PREDICTED: diacylglyce ( 358) 1188 284.7 2e-76 NP_115953 (OMIM: 606983) diacylglycerol O-acyltran ( 388) 1188 284.7 2.1e-76 NP_001240820 (OMIM: 606983) diacylglycerol O-acylt ( 345) 1137 272.8 7.2e-73 NP_835470 (OMIM: 610184) 2-acylglycerol O-acyltran ( 341) 1070 257.2 3.5e-68 NP_079374 (OMIM: 610270) 2-acylglycerol O-acyltran ( 334) 996 240.0 5.1e-63 NP_477513 (OMIM: 610268) 2-acylglycerol O-acyltran ( 335) 953 230.0 5.3e-60 XP_005250366 (OMIM: 610184) PREDICTED: 2-acylglyce ( 344) 909 219.8 6.4e-57 XP_011514428 (OMIM: 610184) PREDICTED: 2-acylglyce ( 305) 907 219.3 8.1e-57 XP_011543569 (OMIM: 610270) PREDICTED: 2-acylglyce ( 336) 899 217.5 3.2e-56 NP_001274076 (OMIM: 610184) 2-acylglycerol O-acylt ( 281) 731 178.4 1.6e-44 XP_011514429 (OMIM: 610184) PREDICTED: 2-acylglyce ( 223) 685 167.6 2.2e-41 >>NP_001013597 (OMIM: 300924) acyl-CoA wax alcohol acylt (328 aa) initn: 2313 init1: 2313 opt: 2313 Z-score: 2906.5 bits: 546.1 E(85289): 3.7e-155 Smith-Waterman score: 2313; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328) 10 20 30 40 50 60 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSHGTGNLVGIVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSHGTGNLVGIVVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHA 250 260 270 280 290 300 310 320 pF1KE0 LYMDALHKLFDQHKTHYGCSETQKLFFL :::::::::::::::::::::::::::: NP_001 LYMDALHKLFDQHKTHYGCSETQKLFFL 310 320 >>XP_016884784 (OMIM: 300924) PREDICTED: acyl-CoA wax al (395 aa) initn: 2299 init1: 1956 opt: 1965 Z-score: 2468.3 bits: 465.3 E(85289): 9.5e-131 Smith-Waterman score: 1965; 98.3% identity (98.3% similar) in 286 aa overlap (1-286:1-285) 10 20 30 40 50 60 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSHGTGNLVGIVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSHGTGNLVGIVVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHA ::::::::::::::::::::::::::::::::::::: :: :: XP_016 QSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTV-GECHSQPQCHLRFLNLNLSLAP 250 260 270 280 290 310 320 pF1KE0 LYMDALHKLFDQHKTHYGCSETQKLFFL XP_016 PKKRAAEGKVGADLGCESQAQGRRGRLKEEEVLTLSSSLFRSLLAVGEPLPLPQIEKPSQ 300 310 320 330 340 350 >-- initn: 365 init1: 357 opt: 357 Z-score: 448.8 bits: 91.6 E(85289): 2.9e-18 Smith-Waterman score: 357; 100.0% identity (100.0% similar) in 51 aa overlap (278-328:345-395) 250 260 270 280 290 300 pF1KE0 FGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHALYMDALH :::::::::::::::::::::::::::::: XP_016 CESQAQGRRGRLKEEEVLTLSSSLFRSLLAVGEPLPLPQIEKPSQEMVDKYHALYMDALH 320 330 340 350 360 370 310 320 pF1KE0 KLFDQHKTHYGCSETQKLFFL ::::::::::::::::::::: XP_016 KLFDQHKTHYGCSETQKLFFL 380 390 >>NP_940914 (OMIM: 300926) diacylglycerol O-acyltransfer (337 aa) initn: 1216 init1: 602 opt: 1231 Z-score: 1547.4 bits: 294.7 E(85289): 1.9e-79 Smith-Waterman score: 1231; 54.6% identity (82.7% similar) in 324 aa overlap (10-325:13-334) 10 20 30 40 50 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYL---AIFWILQPLFVYLLFTSLWPLPVLYFAWLFL .:....::: :. :: .: : : :::...::: :: .::: NP_940 MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYF--LLFSKFWPLAVLSLAWLTY 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 DWKTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFC ::.: .::::::::::: .: ..:.:::. ..::.::::.:::... ::::.:.::.: NP_940 DWNTHSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 NFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-GTGN :: :::::... ::.::: ..:: .: ::.::::.:. ::: ::. :..:::.. :.:: NP_940 NFATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHK : :::::..::: :...::.:..:::::. ::: ::.:::...:::.::..: : . NP_940 AVVIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPE 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 DS--RMYK--FQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEK . :... ::. :..:.:. :.:.:..: .:: :.::..:::.::::::::.:.:.. NP_940 GTWLRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKR 240 250 260 270 280 290 290 300 310 320 pF1KE0 PSQEMVDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL :.:. ::::::::..::.:::::::..:: :::.: NP_940 PNQKTVDKYHALYISALRKLFDQHKVEYGLPETQELTIT 300 310 320 330 >>XP_011529178 (OMIM: 300925) PREDICTED: acyl-CoA wax al (333 aa) initn: 1202 init1: 643 opt: 1222 Z-score: 1536.2 bits: 292.6 E(85289): 7.9e-79 Smith-Waterman score: 1222; 54.3% identity (81.5% similar) in 313 aa overlap (15-325:18-330) 10 20 30 40 50 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLL-FTSLWPLPVLYFAWLFLDW ..:: .: : : . . .::. :: ::. :: ..:: .:: XP_011 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 KTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNF :::.::::: . ::.: .: : ::::. .:::.:. : .::.. :::::.. : : .: XP_011 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 CTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-GTGNLV :::.:::: ::::::.. ::. :: .::.:::.:. :.::::. .:..::.: ::::.: XP_011 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 GIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDS .:.::..: :.:...::.:..:.:::: :::::. :.:...::::..::: .: . XP_011 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 RMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMV . .::. :. . .: :.:::..: ..: ::::::::..:.::::::.:.::.::::.: XP_011 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV 250 260 270 280 290 300 300 310 320 pF1KE0 DKYHALYMDALHKLFDQHKTHYGCSETQKLFFL :::.::.:::.::::::::..: ::::.: XP_011 AKYHTLYIDALRKLFDQHKTKFGISETQELEII 310 320 330 >>NP_001002254 (OMIM: 300925) acyl-CoA wax alcohol acylt (333 aa) initn: 1202 init1: 643 opt: 1222 Z-score: 1536.2 bits: 292.6 E(85289): 7.9e-79 Smith-Waterman score: 1222; 54.3% identity (81.5% similar) in 313 aa overlap (15-325:18-330) 10 20 30 40 50 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLL-FTSLWPLPVLYFAWLFLDW ..:: .: : : . . .::. :: ::. :: ..:: .:: NP_001 MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 KTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNF :::.::::: . ::.: .: : ::::. .:::.:. : .::.. :::::.. : : .: NP_001 KTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 CTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-GTGNLV :::.:::: ::::::.. ::. :: .::.:::.:. :.::::. .:..::.: ::::.: NP_001 ATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 GIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDS .:.::..: :.:...::.:..:.:::: :::::. :.:...::::..::: .: . NP_001 IVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 RMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMV . .::. :. . .: :.:::..: ..: ::::::::..:.::::::.:.::.::::.: NP_001 FVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV 250 260 270 280 290 300 300 310 320 pF1KE0 DKYHALYMDALHKLFDQHKTHYGCSETQKLFFL :::.::.:::.::::::::..: ::::.: NP_001 AKYHTLYIDALRKLFDQHKTKFGISETQELEII 310 320 330 >>XP_011543606 (OMIM: 606983) PREDICTED: diacylglycerol (358 aa) initn: 894 init1: 647 opt: 1188 Z-score: 1493.0 bits: 284.7 E(85289): 2e-76 Smith-Waterman score: 1188; 50.8% identity (79.8% similar) in 327 aa overlap (1-325:29-355) 10 20 30 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPL . .:: ...: . .::: ::.:.. . . XP_011 MDSVKGSPVTGTGSSILSALQDLFSVTWLNRSKVEKQLQVISVLQWVLSFLVLGVACSAI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 FVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDL ..:.. :. : . ::::.:: .::.::..::::: ::::: :: ..:::::: ..::..: XP_011 LMYIFCTDCWLIAVLYFTWLVFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 SPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMA .::..: ::::.. .:::::: :::: :: :::: :.::::. :..: .:::::. XP_011 LTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 KGVCSVSQPAINYLLS-HGTGNLVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHG :.: ::. .:.:::: .:.:: . :::::..:.:.:.:. ... :..:::::. ::.:: XP_011 GGICPVSRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 AHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFRRIFGFYCCVFYGQS-FCQGSTGLLPY : ::: ..:::.::: ::.:.. : :. :.. .:: :.:.:.. : . . ::.:: XP_011 ADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPY 250 260 270 280 290 300 280 290 300 310 320 pF1KE0 SRPIVTVVGEPLPLPQIEKPSQEMVDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL :.::.::::::. .:..:.:.:. .: ::..::.:: ::::.:::..: ::. : XP_011 SKPITTVVGEPITIPKLEHPTQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEVN 310 320 330 340 350 >>NP_115953 (OMIM: 606983) diacylglycerol O-acyltransfer (388 aa) initn: 894 init1: 647 opt: 1188 Z-score: 1492.6 bits: 284.7 E(85289): 2.1e-76 Smith-Waterman score: 1188; 50.8% identity (79.8% similar) in 327 aa overlap (1-325:59-385) 10 20 30 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQ . .:: ...: . .::: ::.:.. . NP_115 GPALSREGSGRWGTGSSILSALQDLFSVTWLNRSKVEKQLQVISVLQWVLSFLVLGVACS 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 PLFVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSAWVRNWCVWTHIRDYFPITILKTK ...:.. :. : . ::::.:: .::.::..::::: ::::: :: ..:::::: ..::. NP_115 AILMYIFCTDCWLIAVLYFTWLVFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTH 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 DLSPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYL .: .::..: ::::.. .:::::: :::: :: :::: :.::::. :..: .:::: NP_115 NLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYL 150 160 170 180 190 200 160 170 180 190 200 pF1KE0 MAKGVCSVSQPAINYLLS-HGTGNLVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQ :. :.: ::. .:.:::: .:.:: . :::::..:.:.:.:. ... :..:::::. ::. NP_115 MSGGICPVSRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALR 210 220 230 240 250 260 210 220 230 240 250 260 pF1KE0 HGAHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFRRIFGFYCCVFYGQS-FCQGSTGLL ::: ::: ..:::.::: ::.:.. : :. :.. .:: :.:.:.. : . . ::. NP_115 HGADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLV 270 280 290 300 310 320 270 280 290 300 310 320 pF1KE0 PYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL :::.::.::::::. .:..:.:.:. .: ::..::.:: ::::.:::..: ::. : NP_115 PYSKPITTVVGEPITIPKLEHPTQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEVN 330 340 350 360 370 380 >>NP_001240820 (OMIM: 606983) diacylglycerol O-acyltrans (345 aa) initn: 843 init1: 596 opt: 1137 Z-score: 1429.2 bits: 272.8 E(85289): 7.2e-73 Smith-Waterman score: 1137; 53.0% identity (81.4% similar) in 296 aa overlap (32-325:47-342) 10 20 30 40 50 60 pF1KE0 AHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPER ...:.. :. : . ::::.:: .::.::.. NP_001 QAEADRSQRSHGGPALSREGSGRWGVACSAILMYIFCTDCWLIAVLYFTWLVFDWNTPKK 20 30 40 50 60 70 70 80 90 100 110 120 pF1KE0 GGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEAT ::::: ::::: :: ..:::::: ..::..: .::..: ::::.. .:::::: :::: NP_001 GGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEAT 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE0 GFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLS-HGTGNLVGIVVG :: :::: :.::::. :..: .:::::. :.: ::. .:.:::: .:.:: . :::: NP_001 EVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNGSGNAIIIVVG 140 150 160 170 180 190 190 200 210 220 230 240 pF1KE0 GVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKF :..:.:.:.:. ... :..:::::. ::.::: ::: ..:::.::: ::.:.. : NP_001 GAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPIYSFGENEVYKQVIFEEGSWGRWV 200 210 220 230 240 250 250 260 270 280 290 pF1KE0 QSCFRRIFGFYCCVFYGQS-FCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYH :. :.. .:: :.:.:.. : . . ::.:::.::.::::::. .:..:.:.:. .: :: NP_001 QKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIPKLEHPTQQDIDLYH 260 270 280 290 300 310 300 310 320 pF1KE0 ALYMDALHKLFDQHKTHYGCSETQKLFFL ..::.:: ::::.:::..: ::. : NP_001 TMYMEALVKLFDKHKTKFGLPETEVLEVN 320 330 340 >>NP_835470 (OMIM: 610184) 2-acylglycerol O-acyltransfer (341 aa) initn: 1001 init1: 565 opt: 1070 Z-score: 1345.1 bits: 257.2 E(85289): 3.5e-68 Smith-Waterman score: 1070; 45.8% identity (75.1% similar) in 325 aa overlap (6-328:17-341) 10 20 30 40 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYF : .:.... :. :..: . ... : ::::::::. :.:. NP_835 MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 AWLFLDWKTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLT .::..:: ::..::::: :.:: .: ..:::.:. ..:: .: :..::..:.::::.. NP_835 VWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 FGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH : .::: ::..:::. :::. : ::.:. .: .: :.:.:. :.: ::. .....::. NP_835 TGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 GT-GNLVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQ :. : :.:::. ::: :::. : ::::::::: ::.::: :::...:::.... NP_835 PQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 VLFHKDSRMYKFQSCFRRIFGFYCCVFYGQS-FCQGSTGLLPYSRPIVTVVGEPLPLPQI : : .. : :....:: :.:.:.. : : ::::.. ::.::::.:.:.:: NP_835 KAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQR 250 260 270 280 290 300 290 300 310 320 pF1KE0 EKPSQEMVDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL .:..: :..:::::: ::..::..:: : . : :. NP_835 LHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI 310 320 330 340 >>NP_079374 (OMIM: 610270) 2-acylglycerol O-acyltransfer (334 aa) initn: 1018 init1: 536 opt: 996 Z-score: 1252.3 bits: 240.0 E(85289): 5.1e-63 Smith-Waterman score: 996; 45.8% identity (72.7% similar) in 319 aa overlap (10-327:15-333) 10 20 30 40 50 pF1KE0 MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLD .:.: .::. .:.::. : :. :::: .: : ::: :: .:: NP_079 MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 WKTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCN :..:::. .: : .: ...:::::...:: .:.: .::. : ::::.:. ::: : NP_079 RDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFAN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 FCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKG-VCSVSQPAINYLLSHGTGNL .:::.::::. :::: ::: :. .:. :: :.:.:. : : : .. : . : .: ::: NP_079 LCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 VGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKD .::.:::. :::.. :.. ::.:..:::::: :: ::: ::: :.:::....::. . NP_079 LGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 SRMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEM : . .:. ...:.:. .:.:.. : : ::.:: :::.::::.:. . . .::.: NP_079 SWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEE 250 260 270 280 290 300 300 310 320 pF1KE0 VDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL :.. : :. : .::. :: ... :.: : NP_079 VNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC 310 320 330 328 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:20:10 2016 done: Wed Nov 2 23:20:10 2016 Total Scan time: 5.710 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]