FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0566, 407 aa 1>>>pF1KE0566 407 - 407 aa - 407 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5470+/-0.00033; mu= 17.0416+/- 0.021 mean_var=79.8326+/-16.210, 0's: 0 Z-trim(116.9): 14 B-trim: 1435 in 1/52 Lambda= 0.143544 statistics sampled from 28429 (28439) to 28429 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.333), width: 16 Scan time: 5.180 The best scores are: opt bits E(85289) NP_006484 (OMIM: 256731,608102) ceroid-lipofuscino ( 407) 2876 604.9 1.1e-172 XP_011533219 (OMIM: 256731,608102) PREDICTED: cero ( 246) 1714 364.1 2.1e-100 >>NP_006484 (OMIM: 256731,608102) ceroid-lipofuscinosis (407 aa) initn: 2876 init1: 2876 opt: 2876 Z-score: 3221.0 bits: 604.9 E(85289): 1.1e-172 Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KE0 MRRNLRLGPSSGADAQGQGAPRPGLAAPRMLLPPASQASRGSGSTGCSLMAQEVDTAQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MRRNLRLGPSSGADAQGQGAPRPGLAAPRMLLPPASQASRGSGSTGCSLMAQEVDTAQGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPYKRFDFRPKPDPYCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPYKRFDFRPKPDPYCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AKYTFCPTGSPIPVMEGDDDIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AKYTFCPTGSPIPVMEGDDDIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISGNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISGNM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FNQMAKWVKQDNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FNQMAKWVKQDNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 IETNYTRIFLYSGEPTYLGNETSVFGPTGNKTLGLAIKRFYYPFKPHLPTKEFLLSLLQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IETNYTRIFLYSGEPTYLGNETSVFGPTGNKTLGLAIKRFYYPFKPHLPTKEFLLSLLQI 310 320 330 340 350 360 370 380 390 400 pF1KE0 FDAVIVHKQFYLFYNFEYWFLPMKFPFIKITYEEIPLPIRNKTLSGL ::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FDAVIVHKQFYLFYNFEYWFLPMKFPFIKITYEEIPLPIRNKTLSGL 370 380 390 400 >>XP_011533219 (OMIM: 256731,608102) PREDICTED: ceroid-l (246 aa) initn: 1714 init1: 1714 opt: 1714 Z-score: 1923.6 bits: 364.1 E(85289): 2.1e-100 Smith-Waterman score: 1714; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KE0 MRRNLRLGPSSGADAQGQGAPRPGLAAPRMLLPPASQASRGSGSTGCSLMAQEVDTAQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRRNLRLGPSSGADAQGQGAPRPGLAAPRMLLPPASQASRGSGSTGCSLMAQEVDTAQGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPYKRFDFRPKPDPYCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPYKRFDFRPKPDPYCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AKYTFCPTGSPIPVMEGDDDIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKYTFCPTGSPIPVMEGDDDIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISGNM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISDGE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FNQMAKWVKQDNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKN XP_011 TEAQRG 407 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:05:42 2016 done: Wed Nov 2 23:05:43 2016 Total Scan time: 5.180 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]