FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0571, 188 aa 1>>>pF1KE0571 188 - 188 aa - 188 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2982+/-0.000328; mu= 13.2949+/- 0.021 mean_var=65.2426+/-13.004, 0's: 0 Z-trim(114.5): 18 B-trim: 0 in 0/54 Lambda= 0.158785 statistics sampled from 24418 (24426) to 24418 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.286), width: 16 Scan time: 4.650 The best scores are: opt bits E(85289) NP_057617 (OMIM: 607297) ninjurin-2 isoform 1 [Hom ( 188) 1188 280.5 1.1e-75 NP_001281274 (OMIM: 607297) ninjurin-2 isoform 2 [ ( 135) 810 193.8 9.8e-50 NP_001281275 (OMIM: 607297) ninjurin-2 isoform 3 [ ( 106) 645 156.0 1.9e-38 NP_004139 (OMIM: 602062) ninjurin-1 [Homo sapiens] ( 152) 431 107.0 1.5e-23 XP_011517018 (OMIM: 602062) PREDICTED: ninjurin-1 ( 102) 333 84.5 6e-17 >>NP_057617 (OMIM: 607297) ninjurin-2 isoform 1 [Homo sa (188 aa) initn: 1188 init1: 1188 opt: 1188 Z-score: 1479.7 bits: 280.5 E(85289): 1.1e-75 Smith-Waterman score: 1188; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KE0 MAGLSRQLCALSHPKKAAETQTAEPGGAHAVCSRHPVRVKGLEGSEMESARENIDLQPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MAGLSRQLCALSHPKKAAETQTAEPGGAHAVCSRHPVRVKGLEGSEMESARENIDLQPGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLA 130 140 150 160 170 180 pF1KE0 ARASRNPL :::::::: NP_057 ARASRNPL >>NP_001281274 (OMIM: 607297) ninjurin-2 isoform 2 [Homo (135 aa) initn: 810 init1: 810 opt: 810 Z-score: 1013.9 bits: 193.8 E(85289): 9.8e-50 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 131 aa overlap (58-188:5-135) 30 40 50 60 70 80 pF1KE0 AHAVCSRHPVRVKGLEGSEMESARENIDLQPGSSDPRSQPINLNHYATKKSVAESMLDVA :::::::::::::::::::::::::::::: NP_001 MMYMPGSSDPRSQPINLNHYATKKSVAESMLDVA 10 20 30 90 100 110 120 130 140 pF1KE0 LFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRL 40 50 60 70 80 90 150 160 170 180 pF1KE0 NQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL ::::::::::::::::::::::::::::::::::::::::: NP_001 NQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL 100 110 120 130 >>NP_001281275 (OMIM: 607297) ninjurin-2 isoform 3 [Homo (106 aa) initn: 645 init1: 645 opt: 645 Z-score: 811.2 bits: 156.0 E(85289): 1.9e-38 Smith-Waterman score: 645; 100.0% identity (100.0% similar) in 106 aa overlap (83-188:1-106) 60 70 80 90 100 110 pF1KE0 NIDLQPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTL :::::::::::::::::::::::::::::: NP_001 MLDVALFMSNAMRLKAVLEQGPSSHYYTTL 10 20 30 120 130 140 150 160 170 pF1KE0 VTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFG 40 50 60 70 80 90 180 pF1KE0 AHKTGFLAARASRNPL :::::::::::::::: NP_001 AHKTGFLAARASRNPL 100 >>NP_004139 (OMIM: 602062) ninjurin-1 [Homo sapiens] (152 aa) initn: 455 init1: 421 opt: 431 Z-score: 543.9 bits: 107.0 E(85289): 1.5e-23 Smith-Waterman score: 432; 53.1% identity (76.9% similar) in 143 aa overlap (47-175:1-143) 20 30 40 50 60 pF1KE0 AAETQTAEPGGAHAVCSRHPVRVKGLEGSEMESARENIDLQ-------PGSSD--P---- :.:. :. .:. ::: : : NP_004 MDSGTEEYELNGGLPPGTPGSPDASPARWG 10 20 30 70 80 90 100 110 120 pF1KE0 -RSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLL : :::.::::.:::.::::::.::.:.:: .::::.::::: .:. ::.:::.::.: NP_004 WRHGPINVNHYASKKSAAESMLDIALLMANASQLKAVVEQGPSFAFYVPLVVLISISLVL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 QVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAAR :. .::::. ... .::. :. .:. ::: :: :::. ::.:.::::::..: NP_004 QIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPLMDMAP 100 110 120 130 140 150 pF1KE0 ASRNPL NP_004 QQ >>XP_011517018 (OMIM: 602062) PREDICTED: ninjurin-1 isof (102 aa) initn: 351 init1: 333 opt: 333 Z-score: 425.2 bits: 84.5 E(85289): 6e-17 Smith-Waterman score: 333; 57.0% identity (84.9% similar) in 93 aa overlap (83-175:1-93) 60 70 80 90 100 110 pF1KE0 NIDLQPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTL :::.::.:.:: .::::.::::: .:. : XP_011 MLDIALLMANASQLKAVVEQGPSFAFYVPL 10 20 30 120 130 140 150 160 170 pF1KE0 VTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFG :.:::.::.::. .::::. ... .::. :. .:. ::: :: :::. ::.:.:::::: XP_011 VVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFG 40 50 60 70 80 90 180 pF1KE0 AHKTGFLAARASRNPL ..: XP_011 VQKPLMDMAPQQ 100 188 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:46:14 2016 done: Wed Nov 2 22:46:14 2016 Total Scan time: 4.650 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]