FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0573, 289 aa 1>>>pF1KE0573 289 - 289 aa - 289 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0640+/-0.00073; mu= 9.3569+/- 0.044 mean_var=162.0012+/-33.033, 0's: 0 Z-trim(115.5): 45 B-trim: 0 in 0/50 Lambda= 0.100766 statistics sampled from 15976 (16021) to 15976 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.492), width: 16 Scan time: 2.320 The best scores are: opt bits E(32554) CCDS45547.2 PABPN1L gene_id:390748|Hs108|chr16 ( 278) 1861 281.6 4.6e-76 CCDS73925.1 PABPN1L gene_id:390748|Hs108|chr16 ( 255) 1325 203.6 1.2e-52 CCDS9592.1 PABPN1 gene_id:8106|Hs108|chr14 ( 306) 576 94.8 8.4e-20 CCDS55906.1 PABPN1 gene_id:100529063|Hs108|chr14 ( 333) 568 93.7 2e-19 >>CCDS45547.2 PABPN1L gene_id:390748|Hs108|chr16 (278 aa) initn: 1900 init1: 1852 opt: 1861 Z-score: 1479.1 bits: 281.6 E(32554): 4.6e-76 Smith-Waterman score: 1861; 96.8% identity (98.2% similar) in 278 aa overlap (1-278:1-277) 10 20 30 40 50 60 pF1KE0 MWPFPSRSLFPPPTQAWLQTVSSDPEAQGWGAWNETKEILGPEGGEGKEEKEEEEDAEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MWPFPSRSLFPPPTQAWLQTVSSDPEAQGWGAWNETKEILGPEGGEGKEEKEEEEDAEED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DKFSGHPKGYAYIEFATKGSVQAAVELDQSLFRGRVIKVLPKRTNFPGISSTDRGGLRGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DKFSGHPKGYAYIEFATKGSVQAAVELDQSLFRGRVIKVLPKRTNFPGISSTDRGGLRGH 190 200 210 220 230 240 250 260 270 280 pF1KE0 PGSRGAPFPHSGLQGRPRLRPQGQNRTPAALTPLWARPLPWVVVSHVIK ::::::::::::::::::::::::::. . ..: : : CCDS45 PGSRGAPFPHSGLQGRPRLRPQGQNRARGKFSP-WFSPY 250 260 270 >>CCDS73925.1 PABPN1L gene_id:390748|Hs108|chr16 (255 aa) initn: 1348 init1: 1323 opt: 1325 Z-score: 1058.4 bits: 203.6 E(32554): 1.2e-52 Smith-Waterman score: 1329; 76.8% identity (85.8% similar) in 267 aa overlap (1-266:1-254) 10 20 30 40 50 60 pF1KE0 MWPFPSRSLFPPPTQAWLQTVSSDPEAQGWGAWNETKEILGPEGGEGKEEKEEEEDAEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MWPFPSRSLFPPPTQAWLQTVSSDPEAQGWGAWNETKEILGPEGGEGKEEKEEEEDAEED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 QDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 AGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILC 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 DKFSGHPKGYAYIEFATKGSV-QAAVELDQSLFRGRVIKVLPKRTNFPGISSTDRGGLRG ::::::::: : .. ::. :.: .... : . :. ....:.: . CCDS73 DKFSGHPKGCCRKEPTSLGSAPQTAGAFEDTQAPG----------GHPSPTAASRAGPGS 190 200 210 220 230 240 250 260 270 280 pF1KE0 HPGSRGAPFPHSGLQGRPRLRPQGQNRTPAALTPLWARPLPWVVVSHVIK .: .: .: .: :.. :..: CCDS73 DHKGRTGPVENSH-HGFHRIK--GKTRF 240 250 >>CCDS9592.1 PABPN1 gene_id:8106|Hs108|chr14 (306 aa) initn: 611 init1: 504 opt: 576 Z-score: 469.0 bits: 94.8 E(32554): 8.4e-20 Smith-Waterman score: 598; 46.2% identity (66.7% similar) in 240 aa overlap (41-273:85-305) 20 30 40 50 60 70 pF1KE0 PPPTQAWLQTVSSDPEAQGWGAWNETKEILGPEGGEGKEEKEEEEDAEEDQDGDAGFLLS :: : : ..:::. .:: : CCDS95 LEPEELLLEPEPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDPG---- 60 70 80 90 100 110 80 90 100 110 120 130 pF1KE0 LLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTAAGQLLSPETV . . : :::::: .: :: : . . .:...:.. . . : .. CCDS95 --------DGAIEDPELEAIKARVREME--EEAEKLKELQNEVEKQMNMSP----PPGNA 120 130 140 150 140 150 160 170 180 190 pF1KE0 GCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILCDKFSGHPKGY : :. . :::.::: ::.::::::::..:::::::: :: :.:::::::::::::::. CCDS95 G-PVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGF 160 170 180 190 200 210 200 210 220 230 240 pF1KE0 AYIEFATKGSVQAAVELDQSLFRGRVIKVLPKRTNFPGISSTDRGGLRGHPGSRGAPFP- :::::. : ::.... ::.:::::: :::.::::: ::::.:::: :.. .: . . CCDS95 AYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGISTTDRGFPRARYRARTTNYNS 220 230 240 250 260 270 250 260 270 280 pF1KE0 -----HSGLQGRPRLRP-QGQNRTPAALTPLWARPLPWVVVSHVIK .::...::: : .:. :. . .: CCDS95 SRSRFYSGFNSRPRGRVYRGRARATSWYSPY 280 290 300 >>CCDS55906.1 PABPN1 gene_id:100529063|Hs108|chr14 (333 aa) initn: 567 init1: 504 opt: 568 Z-score: 462.2 bits: 93.7 E(32554): 2e-19 Smith-Waterman score: 568; 51.3% identity (73.3% similar) in 195 aa overlap (86-273:145-332) 60 70 80 90 100 110 pF1KE0 DAEEDQDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEE :::::: .: :: : . . .:...:. CCDS55 MEPLVGQVQEWMVAYLETQLADWIHSSGGWELEAIKARVREME--EEAEKLKELQNEVEK 120 130 140 150 160 170 120 130 140 150 160 170 pF1KE0 EEGTAAGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHR . . . : ..: :. . :::.::: ::.::::::::..:::::::: :: :.: CCDS55 QMNMSP----PPGNAG-PVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNR 180 190 200 210 220 180 190 200 210 220 230 pF1KE0 VTILCDKFSGHPKGYAYIEFATKGSVQAAVELDQSLFRGRVIKVLPKRTNFPGISSTDRG ::::::::::::::.:::::. : ::.... ::.:::::: :::.::::: ::::.:::: CCDS55 VTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGISTTDRG 230 240 250 260 270 280 240 250 260 270 280 pF1KE0 GLRGHPGSRGAPFP------HSGLQGRPRLRP-QGQNRTPAALTPLWARPLPWVVVSHVI :.. .: . . .::...::: : .:. :. . .: CCDS55 FPRARYRARTTNYNSSRSRFYSGFNSRPRGRVYRGRARATSWYSPY 290 300 310 320 330 pF1KE0 K 289 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:41:00 2016 done: Wed Nov 2 22:41:01 2016 Total Scan time: 2.320 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]