FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0575, 352 aa 1>>>pF1KE0575 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2301+/-0.000347; mu= 17.4063+/- 0.022 mean_var=83.2386+/-16.479, 0's: 0 Z-trim(115.7): 215 B-trim: 22 in 1/56 Lambda= 0.140576 statistics sampled from 26033 (26267) to 26033 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.308), width: 16 Scan time: 6.180 The best scores are: opt bits E(85289) NP_001309097 (OMIM: 604946,609423) killer cell imm ( 444) 900 192.3 1.7e-48 NP_037421 (OMIM: 604946,609423) killer cell immuno ( 444) 890 190.3 7e-48 XP_016885763 (OMIM: 604946,609423) PREDICTED: kill ( 397) 876 187.4 4.6e-47 XP_016885732 (OMIM: 604954) PREDICTED: LOW QUALITY ( 454) 853 182.8 1.3e-45 XP_016885771 (OMIM: 604956) PREDICTED: LOW QUALITY ( 541) 827 177.6 5.6e-44 XP_016885733 (OMIM: 604956) PREDICTED: LOW QUALITY ( 541) 827 177.6 5.6e-44 XP_016885756 (OMIM: 604956) PREDICTED: LOW QUALITY ( 541) 824 177.0 8.6e-44 XP_011524692 (OMIM: 604812) PREDICTED: leukocyte i ( 366) 679 147.4 4.6e-35 NP_006857 (OMIM: 604812) leukocyte immunoglobulin- ( 466) 679 147.5 5.5e-35 XP_011524687 (OMIM: 604812) PREDICTED: leukocyte i ( 483) 679 147.5 5.6e-35 NP_001124389 (OMIM: 604812) leukocyte immunoglobul ( 483) 679 147.5 5.6e-35 XP_006723049 (OMIM: 604812) PREDICTED: leukocyte i ( 490) 679 147.5 5.7e-35 NP_001277200 (OMIM: 604812) leukocyte immunoglobul ( 490) 679 147.5 5.7e-35 NP_001265335 (OMIM: 604815) leukocyte immunoglobul ( 455) 673 146.3 1.3e-34 NP_001265334 (OMIM: 604815) leukocyte immunoglobul ( 510) 673 146.3 1.4e-34 NP_001265332 (OMIM: 604815) leukocyte immunoglobul ( 597) 673 146.4 1.5e-34 NP_001074447 (OMIM: 604815) leukocyte immunoglobul ( 597) 673 146.4 1.5e-34 NP_005865 (OMIM: 604815) leukocyte immunoglobulin- ( 598) 673 146.4 1.5e-34 XP_016881713 (OMIM: 604812) PREDICTED: leukocyte i ( 391) 654 142.4 1.6e-33 NP_001265248 (OMIM: 604810) leukocyte immunoglobul ( 439) 644 140.4 7.2e-33 NP_006854 (OMIM: 604810) leukocyte immunoglobulin- ( 489) 644 140.4 7.8e-33 NP_001265328 (OMIM: 604811) leukocyte immunoglobul ( 456) 641 139.8 1.1e-32 XP_011524640 (OMIM: 604811) PREDICTED: leukocyte i ( 460) 641 139.8 1.1e-32 XP_016881681 (OMIM: 604811) PREDICTED: leukocyte i ( 492) 641 139.8 1.2e-32 XP_011524638 (OMIM: 604811) PREDICTED: leukocyte i ( 598) 641 139.9 1.4e-32 XP_016881680 (OMIM: 604811) PREDICTED: leukocyte i ( 599) 641 139.9 1.4e-32 XP_011524637 (OMIM: 604811) PREDICTED: leukocyte i ( 609) 641 139.9 1.4e-32 NP_001265327 (OMIM: 604811) leukocyte immunoglobul ( 634) 641 139.9 1.4e-32 XP_016881674 (OMIM: 604811) PREDICTED: leukocyte i ( 650) 641 139.9 1.5e-32 NP_006660 (OMIM: 604811) leukocyte immunoglobulin- ( 650) 641 139.9 1.5e-32 NP_001075108 (OMIM: 604811) leukocyte immunoglobul ( 651) 641 139.9 1.5e-32 NP_001075107 (OMIM: 604811) leukocyte immunoglobul ( 651) 641 139.9 1.5e-32 NP_001075106 (OMIM: 604811) leukocyte immunoglobul ( 652) 641 139.9 1.5e-32 XP_016881672 (OMIM: 604811) PREDICTED: leukocyte i ( 660) 641 139.9 1.5e-32 XP_016881673 (OMIM: 604811) PREDICTED: leukocyte i ( 660) 641 139.9 1.5e-32 XP_011524634 (OMIM: 604811) PREDICTED: leukocyte i ( 661) 641 139.9 1.5e-32 XP_016881671 (OMIM: 604811) PREDICTED: leukocyte i ( 661) 641 139.9 1.5e-32 XP_011524633 (OMIM: 604811) PREDICTED: leukocyte i ( 662) 641 139.9 1.5e-32 XP_016881679 (OMIM: 604811) PREDICTED: leukocyte i ( 667) 641 139.9 1.5e-32 XP_016881678 (OMIM: 604811) PREDICTED: leukocyte i ( 668) 641 139.9 1.5e-32 XP_016881677 (OMIM: 604811) PREDICTED: leukocyte i ( 668) 641 139.9 1.5e-32 XP_016881676 (OMIM: 604811) PREDICTED: leukocyte i ( 669) 641 139.9 1.5e-32 XP_016881675 (OMIM: 604811) PREDICTED: leukocyte i ( 669) 641 139.9 1.5e-32 NP_006855 (OMIM: 604820) leukocyte immunoglobulin- ( 631) 638 139.3 2.2e-32 NP_001074919 (OMIM: 604820) leukocyte immunoglobul ( 632) 638 139.3 2.2e-32 NP_001307889 (OMIM: 604820) leukocyte immunoglobul ( 648) 638 139.3 2.2e-32 XP_011524683 (OMIM: 604820) PREDICTED: leukocyte i ( 649) 638 139.3 2.2e-32 XP_011524684 (OMIM: 604820) PREDICTED: leukocyte i ( 649) 638 139.3 2.2e-32 XP_011524690 (OMIM: 604812) PREDICTED: leukocyte i ( 425) 628 137.1 6.7e-32 NP_001277199 (OMIM: 604812) leukocyte immunoglobul ( 454) 628 137.2 7e-32 >>NP_001309097 (OMIM: 604946,609423) killer cell immunog (444 aa) initn: 531 init1: 449 opt: 900 Z-score: 991.6 bits: 192.3 E(85289): 1.7e-48 Smith-Waterman score: 900; 47.2% identity (71.3% similar) in 303 aa overlap (5-305:5-303) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI .... :.:: : :. ::.:.::: :::::: ::: ::.::: :: . :: . . NP_001 MLLMVVSMACVGFFLVQRAGPHVGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 FQTTGTRSHELHTGL-SNNITISPVTPEHAGTYRCVGIYKHA-SKWSAESNSLKIIVTGL .. . .: : ......:::: :::.: : : . :. . ::: :: . :.::: NP_001 YKEDRIHVPIFHGRLFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 FTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVEA :::. :::. ::..: :: :.: :.. :..:.:.::: . ..: .. :. .: NP_001 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVS--KA 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLGE ::.::. : ::.::: : .:. :. ::::::::::.:: :.:::::.: : .. :: NP_001 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYGS ..:: :::. :.:.::: :.: :: . : . .. ..:::.: .: :: ::::::.:: NP_001 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 FNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ : :::. NP_001 FRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLL 300 310 320 330 340 350 >>NP_037421 (OMIM: 604946,609423) killer cell immunoglob (444 aa) initn: 519 init1: 437 opt: 890 Z-score: 980.7 bits: 190.3 E(85289): 7e-48 Smith-Waterman score: 890; 46.3% identity (70.7% similar) in 307 aa overlap (1-305:1-303) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI :. .... :.:. : :. :: :.::: :::::: ::: ::.::: :: . :: . . NP_037 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 FQTTGTRSHELHTGL-SNNITISPVTPEHAGTYRCVGIYKHA-SKWSAESNSLKIIVTGL .. . .: . ......:::: :::.: : : . :. . ::: :: . :.::: NP_037 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 FTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVEA :::. :::. ::..: :: :.: :.. :..:.:.::: . ..: .. :. .: NP_037 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVS--KA 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLGE ::.::. : ::.::: : .:. :. ::::::::::.:: :.:::::.: : .. :: NP_037 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYGS ..:: :::. :.:.::: :.: :: . : . .. ..:::.: .: :: ::::::.:: NP_037 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATH--GGTYRCFGS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 FNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ : :::. NP_037 FRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLL 300 310 320 330 340 350 >>XP_016885763 (OMIM: 604946,609423) PREDICTED: killer c (397 aa) initn: 496 init1: 405 opt: 876 Z-score: 966.0 bits: 187.4 E(85289): 4.6e-47 Smith-Waterman score: 876; 47.6% identity (69.1% similar) in 307 aa overlap (1-305:1-303) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI :. .... :.:: : : : :.::: ::::::::: : .:.:.:.:.: : ... XP_016 MSLMVVSMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 FQTTGTRSHELHTGL-SNNITISPVTPEHAGTYRCVGIYKH-ASKWSAESNSLKIIVTGL . : ::.. . :.. :.:::: ::::::: : . : . ::: :: : :.:::. XP_016 SKEDGMPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 FTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVEA :::. :::. ::.. : :.: :.. :..:.:..::... . .: .. :. .: XP_016 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVS--KA 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLGE ::.: .: ::.::: : :: :. ::::::::::::: :::::.: ::.. :: XP_016 NFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYGS ..:: :::. :.: ::: :.: :: . . . .::::: .: :: ::::::.:: XP_016 SVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATH--GGTYRCFGS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 FNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ : ::::. XP_016 FRDSPYEWSDLSDPLLVSVTDVFCSLHTLETQWGSLLWGLGEGLPGTRRISKLDDNMTGG 300 310 320 330 340 350 >>XP_016885732 (OMIM: 604954) PREDICTED: LOW QUALITY PRO (454 aa) initn: 735 init1: 355 opt: 853 Z-score: 940.0 bits: 182.8 E(85289): 1.3e-45 Smith-Waterman score: 853; 46.6% identity (69.1% similar) in 307 aa overlap (1-305:1-302) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI :. .:.. :.:: : :: :.::: ::.::: ::: .::: :::.: : ... XP_016 MSLMVISMACVGFFWLQGAWPHEGGQDKPLLSTWPSLVVP-PEHVTLRCHSNLGFNNFSL 10 20 30 40 50 70 80 90 100 110 pF1KE0 FQTTGTRSHELHTGLS-NNITISPVTPEHAGTYRCVGIYKHA-SKWSAESNSLKIIVTGL .. :. : .. . ... ..:::: :.::::: : . :. : ::: :: : :.:::. XP_016 YKDDGVPVPEHYNRIFWKSLFMGPVTPSHTGTYRCRGSHPHSPSGWSAPSNPLLIMVTGF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 FTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVEA :::. :::. ::.. : :.: :.. :..:.:..:: .. . .: :. .: XP_016 RRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGTFNDTLRLIGEHIDGVS--KA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLGE ::.: . ::.::: : :: :..::::::::::::: :.:::::.: : . :: XP_016 NFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYGS ..:: ::: :.:.::: .: :: . .:.: . .:::.: .: :: ::::::.:: XP_016 SVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGTFQADFPLGPATQ--GGTYRCFGS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 FNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ :.::::. XP_016 FHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKLPFTILL 300 310 320 330 340 350 >>XP_016885771 (OMIM: 604956) PREDICTED: LOW QUALITY PRO (541 aa) initn: 731 init1: 361 opt: 827 Z-score: 910.5 bits: 177.6 E(85289): 5.6e-44 Smith-Waterman score: 827; 48.1% identity (70.7% similar) in 287 aa overlap (21-305:108-389) 10 20 30 40 50 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCH :: :.::: ::.::: ::: .::: :: XP_016 YGPGVEIWAWGGDMGLEWRYGTEVEIWGAWPHEGGQDKPLLSTWPSLVVP-PEHVTLRCH 80 90 100 110 120 130 60 70 80 90 100 pF1KE0 SHLRFVIWTIFQTTGTRSHELHTGLS-NNITISPVTPEHAGTYRCVGIYKHA-SKWSAES :.: : ..... :. ::.. . ... ..:::: :.::::: : . :. : :: : XP_016 SNLGFNNFSLYKDDGVPVPELYNRIFWKSLFMGPVTPSHTGTYRCRGSHTHSPSGGSAPS 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 NSLKIIVTGLFTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQG : : :.:::. :::. :::. ::.. : :.: :.. :..:.:..:: ..:. .: XP_016 NPLVIVVTGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGE 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE0 MEAGIHYVEAVFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLST :. .. ::.: .: ::.::: : .:: :. ::::::::::::: :.:::::. XP_016 HIDGVS--KGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSA 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE0 QVDPMMRLGEKLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPV : : . ::..:: :::. :.:.::: :.: :: . : .: . ..:::.: . :: XP_016 QPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATH- 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE0 PGGTYRCYGSFNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICS ::::::.::: ::::. XP_016 -GGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTS 380 390 400 410 420 430 >>XP_016885733 (OMIM: 604956) PREDICTED: LOW QUALITY PRO (541 aa) initn: 731 init1: 361 opt: 827 Z-score: 910.5 bits: 177.6 E(85289): 5.6e-44 Smith-Waterman score: 827; 48.1% identity (70.7% similar) in 287 aa overlap (21-305:108-389) 10 20 30 40 50 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCH :: :.::: ::.::: ::: .::: :: XP_016 YGPGVEIWAWGGDMGLEWRYGTEVEIWGAWPHEGGQDKPLLSTWPSLVVP-PEHVTLRCH 80 90 100 110 120 130 60 70 80 90 100 pF1KE0 SHLRFVIWTIFQTTGTRSHELHTGLS-NNITISPVTPEHAGTYRCVGIYKHA-SKWSAES :.: : ..... :. ::.. . ... ..:::: :.::::: : . :. : :: : XP_016 SNLGFNNFSLYKDDGVPVPELYNRIFWKSLFMGPVTPSHTGTYRCRGSHTHSPSGGSAPS 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 NSLKIIVTGLFTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQG : : :.:::. :::. :::. ::.. : :.: :.. :..:.:..:: ..:. .: XP_016 NPLVIVVTGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGE 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE0 MEAGIHYVEAVFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLST :. .. ::.: .: ::.::: : .:: :. ::::::::::::: :.:::::. XP_016 HIDGVS--KGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSA 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE0 QVDPMMRLGEKLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPV : : . ::..:: :::. :.:.::: :.: :: . : .: . ..:::.: . :: XP_016 QPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATH- 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE0 PGGTYRCYGSFNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICS ::::::.::: ::::. XP_016 -GGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTS 380 390 400 410 420 430 >>XP_016885756 (OMIM: 604956) PREDICTED: LOW QUALITY PRO (541 aa) initn: 728 init1: 358 opt: 824 Z-score: 907.2 bits: 177.0 E(85289): 8.6e-44 Smith-Waterman score: 824; 48.1% identity (70.4% similar) in 287 aa overlap (21-305:108-389) 10 20 30 40 50 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCH :: :.::: ::.::: ::: .::: :: XP_016 YGPGVEIWAWGGDMGLEWRYGTEVEIWGAWPHEGGQDKPLLSTWPSLVVP-PEHVTLRCH 80 90 100 110 120 130 60 70 80 90 100 pF1KE0 SHLRFVIWTIFQTTGTRSHELHTGLS-NNITISPVTPEHAGTYRCVGIYKHA-SKWSAES :.: : ..... :. ::.. . ... ..:::: :.::::: : . :. : :: : XP_016 SNLGFNNFSLYKDDGVPVPELYNRIFWKSLFMGPVTPSHTGTYRCRGSHTHSPSGGSAPS 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 NSLKIIVTGLFTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQG : : :.:::. :::. :::. ::.. : :.: :.. :..:.:..:: ..:. .: XP_016 NPLVIVVTGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGE 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE0 MEAGIHYVEAVFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLST :. .. ::.: .: ::.::: : .:: :. ::::::::::::: :.:::::. XP_016 HIDGVS--KGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSA 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE0 QVDPMMRLGEKLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPV : : . ::..:: :::. :.:.::: :.: :: . : .: . .:::.: . :: XP_016 QPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGTFQADFPLDPATH- 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE0 PGGTYRCYGSFNDSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICS ::::::.::: ::::. XP_016 -GGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTS 380 390 400 410 420 430 >>XP_011524692 (OMIM: 604812) PREDICTED: leukocyte immun (366 aa) initn: 859 init1: 346 opt: 679 Z-score: 750.5 bits: 147.4 E(85289): 4.6e-35 Smith-Waterman score: 679; 38.3% identity (66.2% similar) in 311 aa overlap (1-307:1-308) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI :.: : ...:::. :. . .:: : .: : :. :. :. ::: :.. :. . . XP_011 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 FQTTGTRS---HELHTGLSNNITISPVTPEHAGTYRCVGIYKHASKWSAESNSLKIIVTG .. . . : . . : .... : .: :::: :.: :.: . : :. :...::: XP_011 YRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHC-QYYSHNHS-SEYSDPLELVVTG 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 LFTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVE ..::..:: :: .: .:. :.:.: :..::: ::: :::. .: :.:.. .: . XP_011 AYSKPTLSALPSPVVTSGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR-GWSW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 AVFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLG :.::.:::.:.. .::: . :.: : :: ::: :.... : ::::::.: ::. : XP_011 AIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 EKLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYG :.::: : :....:.. :...: : : . ::::..: ..: :: ::::. XP_011 ESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 SFN-DSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ . : .: .. : XP_011 AHNLSSEWSAPSDPLDILITAGPHSSPRKERDPAVSVTGAVPHFPSDQGGGRPSPTASEI 300 310 320 330 340 350 >>NP_006857 (OMIM: 604812) leukocyte immunoglobulin-like (466 aa) initn: 611 init1: 346 opt: 679 Z-score: 749.1 bits: 147.5 E(85289): 5.5e-35 Smith-Waterman score: 679; 38.3% identity (66.2% similar) in 311 aa overlap (1-307:1-308) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI :.: : ...:::. :. . .:: : .: : :. :. :. ::: :.. :. . . NP_006 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 FQTTGTRS---HELHTGLSNNITISPVTPEHAGTYRCVGIYKHASKWSAESNSLKIIVTG .. . . : . . : .... : .: :::: :.: :.: . : :. :...::: NP_006 YRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHC-QYYSHNHS-SEYSDPLELVVTG 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 LFTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVE ..::..:: :: .: .:. :.:.: :..::: ::: :::. .: :.:.. .: . NP_006 AYSKPTLSALPSPVVTSGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR-GWSW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 AVFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLG :.::.:::.:.. .::: . :.: : :: ::: :.... : ::::::.: ::. : NP_006 AIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 EKLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYG :.::: : :....:.. :...: : : . ::::..: ..: :: ::::. NP_006 ESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 SFN-DSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ . : .: .. : NP_006 AHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTK 300 310 320 330 340 350 >-- initn: 239 init1: 187 opt: 237 Z-score: 264.7 bits: 57.9 E(85289): 5.3e-08 Smith-Waterman score: 285; 35.6% identity (61.1% similar) in 149 aa overlap (108-254:309-455) 80 90 100 110 120 130 pF1KE0 NITISPVTPEHAGTYRCVGIYKHASKWSAESNSLKIIVTGLF-TKPSISAHPSSLVHAGA :. : :..:: : .::.:..: : : NP_006 NFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGK 280 290 300 310 320 330 140 150 160 170 180 190 pF1KE0 RVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVEAVFSMGPVTPAHAGAYRCC :.: :.:. : :.: ::: . .: . .: . .: : ::::: ::.:.::: NP_006 NVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQA--QQNQAEFRMGPVTSAHVGTYRCY 340 350 360 370 380 390 200 210 220 230 240 250 pF1KE0 GCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLG-EKLTLFCSSEISFDQYHL . .: . : : :::::..:.... . . :. ..:.: :.: . . :. : NP_006 SSLSSNPYLLSLPSDPLELVVSASLGQHPQDYTVENLIRMGVAGLVLVVLGILLFEAQHS 400 410 420 430 440 450 260 270 280 290 300 310 pF1KE0 FRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYGSFNDSPYKPPVTRCNFTP NP_006 QRSLQDAAGR 460 >>XP_011524687 (OMIM: 604812) PREDICTED: leukocyte immun (483 aa) initn: 611 init1: 346 opt: 679 Z-score: 748.9 bits: 147.5 E(85289): 5.6e-35 Smith-Waterman score: 679; 38.3% identity (66.2% similar) in 311 aa overlap (1-307:1-308) 10 20 30 40 50 60 pF1KE0 MAPKLITVLCLGFCLNQKICPHAGAQDKFSLSAWPSPVVPLGGRVTLSCHSHLRFVIWTI :.: : ...:::. :. . .:: : .: : :. :. :. ::: :.. :. . . XP_011 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 FQTTGTRS---HELHTGLSNNITISPVTPEHAGTYRCVGIYKHASKWSAESNSLKIIVTG .. . . : . . : .... : .: :::: :.: :.: . : :. :...::: XP_011 YRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHC-QYYSHNHS-SEYSDPLELVVTG 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 LFTKPSISAHPSSLVHAGARVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVE ..::..:: :: .: .:. :.:.: :..::: ::: :::. .: :.:.. .: . XP_011 AYSKPTLSALPSPVVTSGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR-GWSW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 AVFSMGPVTPAHAGAYRCCGCFSHSRYEWSAPSDPLDIVITGKYKKPSLSTQVDPMMRLG :.::.:::.:.. .::: . :.: : :: ::: :.... : ::::::.: ::. : XP_011 AIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 EKLTLFCSSEISFDQYHLFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYG :.::: : :....:.. :...: : : . ::::..: ..: :: ::::. XP_011 ESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 SFN-DSPYKPPVTRCNFTPQETLRVLLCHSQNPPLNLTHLALKDSPATCICSLDSQ . : .: .. : XP_011 AHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTK 300 310 320 330 340 350 >-- initn: 239 init1: 187 opt: 237 Z-score: 264.4 bits: 57.9 E(85289): 5.4e-08 Smith-Waterman score: 264; 37.3% identity (61.2% similar) in 134 aa overlap (108-238:309-440) 80 90 100 110 120 130 pF1KE0 NITISPVTPEHAGTYRCVGIYKHASKWSAESNSLKIIVTGLF-TKPSISAHPSSLVHAGA :. : :..:: : .::.:..: : : XP_011 NFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGK 280 290 300 310 320 330 140 150 160 170 180 190 pF1KE0 RVSLRCHSELAFDEFILYKEGHIQHSQQLDQGMEAGIHYVEAVFSMGPVTPAHAGAYRCC :.: :.:. : :.: ::: . .: . .: . .: : ::::: ::.:.::: XP_011 NVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE--FRMGPVTSAHVGTYRCY 340 350 360 370 380 390 200 210 220 230 240 250 pF1KE0 GCFSHSRYEWSAPSDPLDIVIT--GKYKKPSLSTQVDPMMRLGEKLTLFCSSEISFDQYH . .: . : : :::::..:.. .. .:: . . ::. XP_011 SSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLGQHPQDYTVENLIRMGVA 400 410 420 430 440 450 260 270 280 290 300 310 pF1KE0 LFRHGVAHGQWLSGGQRHREAFQANFSVGRATPVPGGTYRCYGSFNDSPYKPPVTRCNFT XP_011 GLVLVVLGILLFEAQHSQRSLQDAAGR 460 470 480 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:36:10 2016 done: Wed Nov 2 22:36:11 2016 Total Scan time: 6.180 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]