FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0579, 279 aa 1>>>pF1KE0579 279 - 279 aa - 279 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7164+/-0.000305; mu= 18.1290+/- 0.019 mean_var=58.9260+/-11.823, 0's: 0 Z-trim(115.9): 48 B-trim: 0 in 0/52 Lambda= 0.167079 statistics sampled from 26621 (26671) to 26621 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.313), width: 16 Scan time: 5.370 The best scores are: opt bits E(85289) NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 1909 468.1 7.9e-132 NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 460 118.8 9.3e-27 XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 460 118.8 9.3e-27 NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 451 116.7 5e-26 XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 451 116.7 5e-26 XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 451 116.7 5e-26 NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 451 116.7 5e-26 NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 442 114.5 2.1e-25 NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 442 114.5 2.1e-25 NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 440 114.1 3.2e-25 NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 425 110.4 3.7e-24 NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 425 110.4 3.7e-24 NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 417 108.6 1.8e-23 XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 409 106.6 5.3e-23 NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 409 106.6 5.3e-23 XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 395 103.2 5.6e-22 NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 395 103.2 5.6e-22 NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 388 101.6 2.4e-21 XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 388 101.6 2.4e-21 XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 388 101.6 2.4e-21 NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 388 101.6 2.4e-21 NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 366 96.3 1e-19 XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 355 93.7 6.4e-19 NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 355 93.7 6.4e-19 XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 355 93.7 6.4e-19 XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 346 91.5 2.9e-18 NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 346 91.5 2.9e-18 NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 322 85.7 1.3e-16 XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 322 85.7 1.3e-16 XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 322 85.7 1.3e-16 XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 318 84.7 2.7e-16 NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 318 84.7 2.7e-16 NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 318 84.7 2.7e-16 XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 318 84.7 2.7e-16 NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 313 83.5 6.5e-16 NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 308 82.3 1.3e-15 NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 300 80.5 7.2e-15 NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 298 80.0 1.1e-14 XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 288 77.3 2.8e-14 NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 288 77.3 2.8e-14 XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 249 68.0 2.2e-11 >>NP_853516 (OMIM: 611925) gap junction gamma-3 protein (279 aa) initn: 1909 init1: 1909 opt: 1909 Z-score: 2487.7 bits: 468.1 E(85289): 7.9e-132 Smith-Waterman score: 1909; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:1-279) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 GNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 NLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRR 190 200 210 220 230 240 250 260 270 pF1KE0 HKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA ::::::::::::::::::::::::::::::::::::::: NP_853 HKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA 250 260 270 >>NP_003995 (OMIM: 121011,124500,148210,148350,149200,22 (226 aa) initn: 360 init1: 360 opt: 460 Z-score: 601.4 bits: 118.8 E(85289): 9.3e-27 Smith-Waterman score: 460; 36.8% identity (68.4% similar) in 212 aa overlap (6-213:6-213) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC :. .:. ...:: .:.. : ::. ::...:.... :.::::..:::.: :::: NP_003 MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLY--HVIWHWELSGKGKEEETLIQG : .:.: . :.: .:.:..:.:.:..:. : . : : . ..:. : : :. NP_003 KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIE- 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 REGNTD-VPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLG : .:. : ::: :.:.... :...:.: . . : .: ::.: : :: . NP_003 -EIKTQKVRIEGSL--WWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSE .. : .:::.:::.: :..:::.:.:.. :: : NP_003 TVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV 180 190 200 210 220 240 250 260 270 pF1KE0 STRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA >>XP_011533351 (OMIM: 121011,124500,148210,148350,149200 (226 aa) initn: 360 init1: 360 opt: 460 Z-score: 601.4 bits: 118.8 E(85289): 9.3e-27 Smith-Waterman score: 460; 36.8% identity (68.4% similar) in 212 aa overlap (6-213:6-213) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC :. .:. ...:: .:.. : ::. ::...:.... :.::::..:::.: :::: XP_011 MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLY--HVIWHWELSGKGKEEETLIQG : .:.: . :.: .:.:..:.:.:..:. : . : : . ..:. : : :. XP_011 KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIE- 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 REGNTD-VPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLG : .:. : ::: :.:.... :...:.: . . : .: ::.: : :: . XP_011 -EIKTQKVRIEGSL--WWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSE .. : .:::.:::.: :..:::.:.:.. :: : XP_011 TVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV 180 190 200 210 220 240 250 260 270 pF1KE0 STRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA >>NP_001091111 (OMIM: 302800,304040) gap junction beta-1 (283 aa) initn: 443 init1: 282 opt: 451 Z-score: 588.3 bits: 116.7 E(85289): 5e-26 Smith-Waterman score: 451; 36.0% identity (67.8% similar) in 214 aa overlap (6-213:6-212) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC : ::. .:.:: .::. : :.. ::...:.... .:.:::.: :.:.: :::: NP_001 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWE-----LSGKGKEEETL ...:.: : :.: .:.: .:.:::..: :: ... . : : : : :.: . : NP_001 NSVCYDQFFPISHVRLWSLQLILVSTP-ALLVAMHVAHQ-QHIEKKMLRLEGHG-DPLHL 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 IQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPC . .. .. . :. : :.:: .. ::..:.. . . : :: :. : : :: NP_001 EEVKRHKVHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPC 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLT ... : .:::.:::.: :...::.:.... :.: : NP_001 PNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGS 180 190 200 210 220 230 240 250 260 270 pF1KE0 SESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA NP_001 GFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 240 250 260 270 280 >>XP_011529209 (OMIM: 302800,304040) PREDICTED: gap junc (283 aa) initn: 443 init1: 282 opt: 451 Z-score: 588.3 bits: 116.7 E(85289): 5e-26 Smith-Waterman score: 451; 36.0% identity (67.8% similar) in 214 aa overlap (6-213:6-212) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC : ::. .:.:: .::. : :.. ::...:.... .:.:::.: :.:.: :::: XP_011 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWE-----LSGKGKEEETL ...:.: : :.: .:.: .:.:::..: :: ... . : : : : :.: . : XP_011 NSVCYDQFFPISHVRLWSLQLILVSTP-ALLVAMHVAHQ-QHIEKKMLRLEGHG-DPLHL 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 IQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPC . .. .. . :. : :.:: .. ::..:.. . . : :: :. : : :: XP_011 EEVKRHKVHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPC 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLT ... : .:::.:::.: :...::.:.... :.: : XP_011 PNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGS 180 190 200 210 220 230 240 250 260 270 pF1KE0 SESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA XP_011 GFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 240 250 260 270 280 >>XP_016884897 (OMIM: 302800,304040) PREDICTED: gap junc (283 aa) initn: 443 init1: 282 opt: 451 Z-score: 588.3 bits: 116.7 E(85289): 5e-26 Smith-Waterman score: 451; 36.0% identity (67.8% similar) in 214 aa overlap (6-213:6-212) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC : ::. .:.:: .::. : :.. ::...:.... .:.:::.: :.:.: :::: XP_016 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWE-----LSGKGKEEETL ...:.: : :.: .:.: .:.:::..: :: ... . : : : : :.: . : XP_016 NSVCYDQFFPISHVRLWSLQLILVSTP-ALLVAMHVAHQ-QHIEKKMLRLEGHG-DPLHL 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 IQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPC . .. .. . :. : :.:: .. ::..:.. . . : :: :. : : :: XP_016 EEVKRHKVHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPC 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLT ... : .:::.:::.: :...::.:.... :.: : XP_016 PNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGS 180 190 200 210 220 230 240 250 260 270 pF1KE0 SESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA XP_016 GFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 240 250 260 270 280 >>NP_000157 (OMIM: 302800,304040) gap junction beta-1 pr (283 aa) initn: 443 init1: 282 opt: 451 Z-score: 588.3 bits: 116.7 E(85289): 5e-26 Smith-Waterman score: 451; 36.0% identity (67.8% similar) in 214 aa overlap (6-213:6-212) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC : ::. .:.:: .::. : :.. ::...:.... .:.:::.: :.:.: :::: NP_000 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWE-----LSGKGKEEETL ...:.: : :.: .:.: .:.:::..: :: ... . : : : : :.: . : NP_000 NSVCYDQFFPISHVRLWSLQLILVSTP-ALLVAMHVAHQ-QHIEKKMLRLEGHG-DPLHL 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 IQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPC . .. .. . :. : :.:: .. ::..:.. . . : :: :. : : :: NP_000 EEVKRHKVHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPC 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLT ... : .:::.:::.: :...::.:.... :.: : NP_000 PNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGS 180 190 200 210 220 230 240 250 260 270 pF1KE0 SESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA NP_000 GFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 240 250 260 270 280 >>NP_001103691 (OMIM: 129500,220290,304400,604418,612643 (261 aa) initn: 364 init1: 334 opt: 442 Z-score: 577.1 bits: 114.5 E(85289): 2.1e-25 Smith-Waterman score: 442; 28.8% identity (68.4% similar) in 250 aa overlap (6-247:6-251) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC :. ... ...:: .:.. . :.. ::...:.... :.:::: .:::.: :::: NP_001 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQ : .:.: : :.: .:.:..:.:.:..:. :..... ... ... . : .. . . . NP_001 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 GREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLG .. .. . :. : :.:.... :...:.: . . : :: :...: . : .:: . NP_001 IKKQKVRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLG----RWWRTWKHKSSSSKYF . : .:::.:::.: :...: .:.:.. :: : : : :. .:. .. . NP_001 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHAL 180 190 200 210 220 230 240 250 260 270 pF1KE0 LTSESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA :.... .. .:: NP_001 KESKQNEMNELISDSGQNAITGFPS 240 250 260 >>XP_016875849 (OMIM: 129500,220290,304400,604418,612643 (261 aa) initn: 364 init1: 334 opt: 442 Z-score: 577.1 bits: 114.5 E(85289): 2.1e-25 Smith-Waterman score: 442; 28.8% identity (68.4% similar) in 250 aa overlap (6-247:6-251) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC :. ... ...:: .:.. . :.. ::...:.... :.:::: .:::.: :::: XP_016 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQ : .:.: : :.: .:.:..:.:.:..:. :..... ... ... . : .. . . . XP_016 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 GREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLG .. .. . :. : :.:.... :...:.: . . : :: :...: . : .:: . XP_016 IKKQKVRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLG----RWWRTWKHKSSSSKYF . : .:::.:::.: :...: .:.:.. :: : : : :. .:. .. . XP_016 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHAL 180 190 200 210 220 230 240 250 260 270 pF1KE0 LTSESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA :.... .. .:: XP_016 KESKQNEMNELISDSGQNAITGFPS 240 250 260 >>XP_016875848 (OMIM: 129500,220290,304400,604418,612643 (261 aa) initn: 364 init1: 334 opt: 442 Z-score: 577.1 bits: 114.5 E(85289): 2.1e-25 Smith-Waterman score: 442; 28.8% identity (68.4% similar) in 250 aa overlap (6-247:6-251) 10 20 30 40 50 60 pF1KE0 MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC :. ... ...:: .:.. . :.. ::...:.... :.:::: .:::.: :::: XP_016 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KAACFDAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQ : .:.: : :.: .:.:..:.:.:..:. :..... ... ... . : .. . . . XP_016 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 GREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLG .. .. . :. : :.:.... :...:.: . . : :: :...: . : .:: . XP_016 IKKQKVRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLG----RWWRTWKHKSSSSKYF . : .:::.:::.: :...: .:.:.. :: : : : :. .:. .. . XP_016 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHAL 180 190 200 210 220 230 240 250 260 270 pF1KE0 LTSESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA :.... .. .:: XP_016 KESKQNEMNELISDSGQNAITGFPS 240 250 260 279 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:10:52 2016 done: Wed Nov 2 22:10:53 2016 Total Scan time: 5.370 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]