FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0583, 272 aa 1>>>pF1KE0583 272 - 272 aa - 272 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5644+/-0.000311; mu= 9.6455+/- 0.019 mean_var=99.4361+/-19.711, 0's: 0 Z-trim(119.7): 4 B-trim: 51 in 1/55 Lambda= 0.128618 statistics sampled from 34043 (34047) to 34043 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.399), width: 16 Scan time: 5.910 The best scores are: opt bits E(85289) NP_000408 (OMIM: 147730,601942,606367) interleukin ( 272) 1895 361.3 1.1e-99 NP_001295171 (OMIM: 147730,601942,606367) interleu ( 200) 871 171.3 1.3e-42 NP_001295172 (OMIM: 147730,601942,606367) interleu ( 176) 862 169.6 3.7e-42 >>NP_000408 (OMIM: 147730,601942,606367) interleukin-2 r (272 aa) initn: 1895 init1: 1895 opt: 1895 Z-score: 1910.9 bits: 361.3 E(85289): 1.1e-99 Smith-Waterman score: 1895; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272) 10 20 30 40 50 60 pF1KE0 MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ 190 200 210 220 230 240 250 260 270 pF1KE0 VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI :::::::::::::::::::::::::::::::: NP_000 VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI 250 260 270 >>NP_001295171 (OMIM: 147730,601942,606367) interleukin- (200 aa) initn: 887 init1: 870 opt: 871 Z-score: 886.1 bits: 171.3 E(85289): 1.3e-42 Smith-Waterman score: 1204; 73.5% identity (73.5% similar) in 272 aa overlap (1-272:1-200) 10 20 30 40 50 60 pF1KE0 MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQP ::: NP_001 LPG--------------------------------------------------------- 190 200 210 220 230 240 pF1KE0 QLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------------EEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ 130 140 150 160 250 260 270 pF1KE0 VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI :::::::::::::::::::::::::::::::: NP_001 VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI 170 180 190 200 >>NP_001295172 (OMIM: 147730,601942,606367) interleukin- (176 aa) initn: 1185 init1: 862 opt: 862 Z-score: 877.9 bits: 169.6 E(85289): 3.7e-42 Smith-Waterman score: 997; 64.7% identity (64.7% similar) in 272 aa overlap (1-272:1-176) 10 20 30 40 50 60 pF1KE0 MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQP :: NP_001 LP---------------------------------------------------------- 190 200 210 220 230 240 pF1KE0 QLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ :::::::::::::::::::::: NP_001 --------------------------------------DFQIQTEMAATMETSIFTTEYQ 130 140 250 260 270 pF1KE0 VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI :::::::::::::::::::::::::::::::: NP_001 VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI 150 160 170 272 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:36:47 2016 done: Wed Nov 2 21:36:47 2016 Total Scan time: 5.910 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]