FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0585, 302 aa 1>>>pF1KE0585 302 - 302 aa - 302 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4904+/-0.000571; mu= -5.3067+/- 0.034 mean_var=554.1821+/-127.056, 0's: 0 Z-trim(116.6): 2046 B-trim: 0 in 0/52 Lambda= 0.054481 statistics sampled from 25142 (27908) to 25142 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.327), width: 16 Scan time: 6.920 The best scores are: opt bits E(85289) NP_598001 (OMIM: 606848) serine/threonine-protein ( 302) 2059 176.9 4.3e-44 XP_016855833 (OMIM: 606848) PREDICTED: serine/thre ( 310) 2033 174.9 1.8e-43 XP_016855834 (OMIM: 606848) PREDICTED: serine/thre ( 310) 2033 174.9 1.8e-43 NP_001159640 (OMIM: 604884) serine/threonine-prote ( 313) 1624 142.8 8.6e-34 XP_006716999 (OMIM: 604884) PREDICTED: serine/thre ( 313) 1624 142.8 8.6e-34 NP_055212 (OMIM: 604884) serine/threonine-protein ( 313) 1624 142.8 8.6e-34 XP_005251721 (OMIM: 604884) PREDICTED: serine/thre ( 313) 1624 142.8 8.6e-34 NP_001159642 (OMIM: 604884) serine/threonine-prote ( 313) 1624 142.8 8.6e-34 NP_001159639 (OMIM: 604884) serine/threonine-prote ( 331) 1624 142.8 8.9e-34 NP_001159641 (OMIM: 604884) serine/threonine-prote ( 338) 1624 142.8 8.9e-34 NP_001138473 (OMIM: 604884) serine/threonine-prote ( 347) 1624 142.8 9.1e-34 NP_001159643 (OMIM: 604884) serine/threonine-prote ( 347) 1624 142.8 9.1e-34 XP_016869706 (OMIM: 604884) PREDICTED: serine/thre ( 347) 1624 142.8 9.1e-34 XP_016855835 (OMIM: 606848) PREDICTED: serine/thre ( 272) 1514 134.0 3.2e-31 XP_016855836 (OMIM: 606848) PREDICTED: serine/thre ( 226) 1277 115.2 1.2e-25 XP_016855837 (OMIM: 606848) PREDICTED: serine/thre ( 226) 1277 115.2 1.2e-25 XP_011507511 (OMIM: 606848) PREDICTED: serine/thre ( 160) 823 79.3 5.4e-15 XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 638 65.8 2.8e-10 XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671) 633 65.4 3.6e-10 NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 638 66.2 3.7e-10 XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 638 66.2 3.7e-10 NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 638 66.2 3.7e-10 XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 638 66.2 3.7e-10 NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 638 66.2 3.7e-10 XP_011530305 (OMIM: 263520,604588) PREDICTED: seri (1258) 638 66.2 3.8e-10 NP_036356 (OMIM: 263520,604588) serine/threonine-p (1258) 638 66.2 3.8e-10 NP_001186326 (OMIM: 263520,604588) serine/threonin (1286) 638 66.2 3.8e-10 XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795) 633 65.5 3.9e-10 XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824) 633 65.5 4e-10 NP_003148 (OMIM: 601959) serine/threonine-protein ( 841) 633 65.5 4e-10 XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842) 633 65.5 4e-10 XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870) 633 65.6 4.1e-10 XP_011533370 (OMIM: 616731) PREDICTED: serine/thre ( 483) 625 64.5 4.7e-10 XP_006719871 (OMIM: 616731) PREDICTED: serine/thre ( 598) 625 64.7 5.2e-10 XP_011533368 (OMIM: 616731) PREDICTED: serine/thre ( 697) 625 64.8 5.6e-10 XP_016876045 (OMIM: 616731) PREDICTED: serine/thre ( 737) 625 64.8 5.8e-10 XP_016876044 (OMIM: 616731) PREDICTED: serine/thre ( 755) 625 64.8 5.9e-10 XP_016876046 (OMIM: 616731) PREDICTED: serine/thre ( 780) 625 64.9 6e-10 NP_954983 (OMIM: 616731) serine/threonine-protein ( 708) 618 64.2 8.3e-10 NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692) 597 62.6 2.6e-09 XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705) 597 62.6 2.6e-09 NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 592 61.9 2.8e-09 NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 592 62.0 2.9e-09 NP_002489 (OMIM: 604044) serine/threonine-protein ( 506) 592 62.0 2.9e-09 NP_665917 (OMIM: 609779) serine/threonine-protein ( 470) 580 61.0 5.3e-09 NP_001308152 (OMIM: 609779) serine/threonine-prote ( 482) 580 61.0 5.4e-09 XP_016862704 (OMIM: 609779) PREDICTED: serine/thre ( 563) 580 61.1 5.9e-09 XP_016862705 (OMIM: 609779) PREDICTED: serine/thre ( 563) 580 61.1 5.9e-09 XP_016862703 (OMIM: 609779) PREDICTED: serine/thre ( 599) 580 61.1 6.1e-09 XP_016862702 (OMIM: 609779) PREDICTED: serine/thre ( 599) 580 61.1 6.1e-09 >>NP_598001 (OMIM: 606848) serine/threonine-protein kina (302 aa) initn: 2059 init1: 2059 opt: 2059 Z-score: 912.6 bits: 176.9 E(85289): 4.3e-44 Smith-Waterman score: 2059; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 ALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 RMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 GLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTA 250 260 270 280 290 300 pF1KE0 SS :: NP_598 SS >>XP_016855833 (OMIM: 606848) PREDICTED: serine/threonin (310 aa) initn: 1242 init1: 1242 opt: 2033 Z-score: 901.4 bits: 174.9 E(85289): 1.8e-43 Smith-Waterman score: 2033; 97.4% identity (97.4% similar) in 310 aa overlap (1-302:1-310) 10 20 30 40 50 60 pF1KE0 MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLS 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 RMIK--------HFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITAT :::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMIKFLFLIFKKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITAT 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAAL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVA 250 260 270 280 290 300 300 pF1KE0 KRMHACTASS :::::::::: XP_016 KRMHACTASS 310 >>XP_016855834 (OMIM: 606848) PREDICTED: serine/threonin (310 aa) initn: 1242 init1: 1242 opt: 2033 Z-score: 901.4 bits: 174.9 E(85289): 1.8e-43 Smith-Waterman score: 2033; 97.4% identity (97.4% similar) in 310 aa overlap (1-302:1-310) 10 20 30 40 50 60 pF1KE0 MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLS 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 RMIK--------HFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITAT :::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMIKFLFLIFKKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITAT 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAAL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVA 250 260 270 280 290 300 300 pF1KE0 KRMHACTASS :::::::::: XP_016 KRMHACTASS 310 >>NP_001159640 (OMIM: 604884) serine/threonine-protein k (313 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.7 bits: 142.8 E(85289): 8.6e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:19-313) 10 20 30 40 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLANFRIEKKIGRGQ .. : :: :: .:. ..: .::.:.::::::::: NP_001 MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLADFQIEKKIGRGQ 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 FSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIED :::::.:.:::: :::::::::..:::::: ::.::: :::::::::.::: ::::: NP_001 FSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 NELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKP ::::::::::::::::.:::.:::::::::::::::::::::::.::::::::::::::: NP_001 NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 ANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 ANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPD :::::::::::::::::::.:::.:::::::::::..::::.::.::.::: :::..::: NP_001 LLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPD 240 250 260 270 280 290 290 300 pF1KE0 VTYVYDVAKRMHACTASS . ::..:::.:: .:. NP_001 IGYVHQVAKQMHIWMSST 300 310 >>XP_006716999 (OMIM: 604884) PREDICTED: serine/threonin (313 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.7 bits: 142.8 E(85289): 8.6e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:19-313) 10 20 30 40 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLANFRIEKKIGRGQ .. : :: :: .:. ..: .::.:.::::::::: XP_006 MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLADFQIEKKIGRGQ 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 FSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIED :::::.:.:::: :::::::::..:::::: ::.::: :::::::::.::: ::::: XP_006 FSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 NELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKP ::::::::::::::::.:::.:::::::::::::::::::::::.::::::::::::::: XP_006 NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 ANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_006 ANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPD :::::::::::::::::::.:::.:::::::::::..::::.::.::.::: :::..::: XP_006 LLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPD 240 250 260 270 280 290 290 300 pF1KE0 VTYVYDVAKRMHACTASS . ::..:::.:: .:. XP_006 IGYVHQVAKQMHIWMSST 300 310 >>NP_055212 (OMIM: 604884) serine/threonine-protein kina (313 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.7 bits: 142.8 E(85289): 8.6e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:19-313) 10 20 30 40 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLANFRIEKKIGRGQ .. : :: :: .:. ..: .::.:.::::::::: NP_055 MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLADFQIEKKIGRGQ 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 FSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIED :::::.:.:::: :::::::::..:::::: ::.::: :::::::::.::: ::::: NP_055 FSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 NELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKP ::::::::::::::::.:::.:::::::::::::::::::::::.::::::::::::::: NP_055 NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 ANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_055 ANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPD :::::::::::::::::::.:::.:::::::::::..::::.::.::.::: :::..::: NP_055 LLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPD 240 250 260 270 280 290 290 300 pF1KE0 VTYVYDVAKRMHACTASS . ::..:::.:: .:. NP_055 IGYVHQVAKQMHIWMSST 300 310 >>XP_005251721 (OMIM: 604884) PREDICTED: serine/threonin (313 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.7 bits: 142.8 E(85289): 8.6e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:19-313) 10 20 30 40 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLANFRIEKKIGRGQ .. : :: :: .:. ..: .::.:.::::::::: XP_005 MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLADFQIEKKIGRGQ 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 FSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIED :::::.:.:::: :::::::::..:::::: ::.::: :::::::::.::: ::::: XP_005 FSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 NELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKP ::::::::::::::::.:::.:::::::::::::::::::::::.::::::::::::::: XP_005 NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 ANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_005 ANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPD :::::::::::::::::::.:::.:::::::::::..::::.::.::.::: :::..::: XP_005 LLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPD 240 250 260 270 280 290 290 300 pF1KE0 VTYVYDVAKRMHACTASS . ::..:::.:: .:. XP_005 IGYVHQVAKQMHIWMSST 300 310 >>NP_001159642 (OMIM: 604884) serine/threonine-protein k (313 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.7 bits: 142.8 E(85289): 8.6e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:19-313) 10 20 30 40 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLANFRIEKKIGRGQ .. : :: :: .:. ..: .::.:.::::::::: NP_001 MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLADFQIEKKIGRGQ 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 FSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIED :::::.:.:::: :::::::::..:::::: ::.::: :::::::::.::: ::::: NP_001 FSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 NELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKP ::::::::::::::::.:::.:::::::::::::::::::::::.::::::::::::::: NP_001 NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 ANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 ANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPD :::::::::::::::::::.:::.:::::::::::..::::.::.::.::: :::..::: NP_001 LLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPD 240 250 260 270 280 290 290 300 pF1KE0 VTYVYDVAKRMHACTASS . ::..:::.:: .:. NP_001 IGYVHQVAKQMHIWMSST 300 310 >>NP_001159639 (OMIM: 604884) serine/threonine-protein k (331 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.4 bits: 142.8 E(85289): 8.9e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:37-331) 10 20 30 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLA .. : :: :: .:. ..: .:: NP_001 APFRALVRLACRMAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 NFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHP .:.::::::::::::::.:.:::: :::::::::..:::::: ::.::: :::::::: NP_001 DFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 NVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHM :.::: :::::::::::::::::::::.:::.:::::::::::::::::::::::.::: NP_001 NIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHM 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 HSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENG ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 HSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 YNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVN :::::::::::::::::::::::::::::::.:::.:::::::::::..::::.::.::. NP_001 YNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVS 250 260 270 280 290 300 280 290 300 pF1KE0 MCINPDPEKRPDVTYVYDVAKRMHACTASS ::: :::..:::. ::..:::.:: .:. NP_001 MCICPDPHQRPDIGYVHQVAKQMHIWMSST 310 320 330 >>NP_001159641 (OMIM: 604884) serine/threonine-protein k (338 aa) initn: 1614 init1: 1614 opt: 1624 Z-score: 727.3 bits: 142.8 E(85289): 8.9e-34 Smith-Waterman score: 1624; 80.0% identity (91.3% similar) in 300 aa overlap (4-302:44-338) 10 20 30 pF1KE0 MDEQSQGMQGPPVPQFQPQK-ALRPDMGYNTLA .. : :: :: .:. ..: .:: NP_001 TQVRALVRLACRMAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFR-----CSLA 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 NFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHP .:.::::::::::::::.:.:::: :::::::::..:::::: ::.::: :::::::: NP_001 DFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 NVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHM :.::: :::::::::::::::::::::.:::.:::::::::::::::::::::::.::: NP_001 NIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHM 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 HSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENG ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 HSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 YNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVN :::::::::::::::::::::::::::::::.:::.:::::::::::..::::.::.::. NP_001 YNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVS 250 260 270 280 290 300 280 290 300 pF1KE0 MCINPDPEKRPDVTYVYDVAKRMHACTASS ::: :::..:::. ::..:::.:: .:. NP_001 MCICPDPHQRPDIGYVHQVAKQMHIWMSST 310 320 330 302 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:18:15 2016 done: Wed Nov 2 21:18:16 2016 Total Scan time: 6.920 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]