FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0589, 462 aa 1>>>pF1KE0589 462 - 462 aa - 462 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1876+/-0.000348; mu= 18.9074+/- 0.022 mean_var=85.2725+/-19.940, 0's: 0 Z-trim(114.7): 217 B-trim: 2584 in 2/55 Lambda= 0.138890 statistics sampled from 24395 (24699) to 24395 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.29), width: 16 Scan time: 6.470 The best scores are: opt bits E(85289) NP_861455 (OMIM: 609046) probable G-protein couple ( 462) 3088 628.9 8.7e-180 NP_001318006 (OMIM: 609046) probable G-protein cou ( 374) 2292 469.3 7.7e-132 NP_001318005 (OMIM: 609046) probable G-protein cou ( 374) 2292 469.3 7.7e-132 NP_115943 (OMIM: 606923) hydroxycarboxylic acid re ( 346) 219 53.9 8e-07 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 216 53.3 1.2e-06 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 216 53.3 1.2e-06 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 216 53.3 1.2e-06 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 216 53.4 1.3e-06 NP_062813 (OMIM: 605773) leukotriene B4 receptor 2 ( 358) 208 51.7 3.8e-06 NP_001158164 (OMIM: 605773) leukotriene B4 recepto ( 358) 208 51.7 3.8e-06 NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 189 48.0 6.2e-05 NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 185 47.2 9.7e-05 NP_002377 (OMIM: 155555,203200,266300,613098,61309 ( 317) 183 46.7 0.00011 NP_005290 (OMIM: 602043) 12-(S)-hydroxy-5,8,10,14- ( 319) 178 45.7 0.00022 NP_003766 (OMIM: 603751) sphingosine 1-phosphate r ( 384) 176 45.3 0.00034 NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 163 42.8 0.0022 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 160 42.1 0.0029 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 160 42.1 0.0029 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 160 42.1 0.0029 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 160 42.1 0.0029 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 160 42.1 0.0031 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 160 42.1 0.0031 NP_006009 (OMIM: 606039) hydroxycarboxylic acid re ( 387) 160 42.1 0.0031 XP_011527129 (OMIM: 162651) PREDICTED: neurotensin ( 336) 159 41.9 0.0033 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 160 42.2 0.0033 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 160 42.2 0.0033 NP_002522 (OMIM: 162651) neurotensin receptor type ( 418) 159 42.0 0.0038 NP_000698 (OMIM: 600264) vasopressin V1b receptor ( 424) 158 41.8 0.0044 XP_016861690 (OMIM: 600552) PREDICTED: chemokine X ( 333) 156 41.3 0.0049 XP_016861687 (OMIM: 600552) PREDICTED: chemokine X ( 333) 156 41.3 0.0049 NP_001019815 (OMIM: 600552) chemokine XC receptor ( 333) 156 41.3 0.0049 XP_016861689 (OMIM: 600552) PREDICTED: chemokine X ( 333) 156 41.3 0.0049 XP_016861685 (OMIM: 600552) PREDICTED: chemokine X ( 333) 156 41.3 0.0049 NP_005274 (OMIM: 600552) chemokine XC receptor 1 [ ( 333) 156 41.3 0.0049 XP_016861688 (OMIM: 600552) PREDICTED: chemokine X ( 333) 156 41.3 0.0049 XP_016861686 (OMIM: 600552) PREDICTED: chemokine X ( 333) 156 41.3 0.0049 NP_057686 (OMIM: 600240) C-C chemokine receptor ty ( 362) 153 40.7 0.0079 NP_808219 (OMIM: 609163) hydroxycarboxylic acid re ( 363) 153 40.7 0.0079 NP_001498 (OMIM: 602885) motilin receptor [Homo sa ( 412) 152 40.6 0.01 >>NP_861455 (OMIM: 609046) probable G-protein coupled re (462 aa) initn: 3088 init1: 3088 opt: 3088 Z-score: 3348.8 bits: 628.9 E(85289): 8.7e-180 Smith-Waterman score: 3088; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462) 10 20 30 40 50 60 pF1KE0 MSIMMLPMEQKIQWVPTSLQDITAVLGTEAYTEEDKSMVSHAQKSQHSCLSHSRWLRSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 MSIMMLPMEQKIQWVPTSLQDITAVLGTEAYTEEDKSMVSHAQKSQHSCLSHSRWLRSPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VTGGSWDLRIRPSKDSSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 VTGGSWDLRIRPSKDSSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 GQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LARLATRTRRPSYYYLLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 LARLATRTRRPSYYYLLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ANHASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 ANHASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 RDTDSPRTLDEVLKWAHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 RDTDSPRTLDEVLKWAHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GITTLFTLLWAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 GITTLFTLLWAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKT 370 380 390 400 410 420 430 440 450 460 pF1KE0 FRATVRQVIHDAYLPCTLASQPEGMAAKPVMEPPGLPTGAEV :::::::::::::::::::::::::::::::::::::::::: NP_861 FRATVRQVIHDAYLPCTLASQPEGMAAKPVMEPPGLPTGAEV 430 440 450 460 >>NP_001318006 (OMIM: 609046) probable G-protein coupled (374 aa) initn: 2290 init1: 2290 opt: 2292 Z-score: 2488.0 bits: 469.3 E(85289): 7.7e-132 Smith-Waterman score: 2292; 96.9% identity (97.8% similar) in 357 aa overlap (106-462:18-374) 80 90 100 110 120 130 pF1KE0 SSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATAGQPRVTLLPTPHVSG :. . : . ::::::::::::::::: NP_001 MLTGSCGDPQKKPQVTQDSGPQSMGLEGRETAGQPRVTLLPTPHVSG 10 20 30 40 140 150 160 170 180 190 pF1KE0 LSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYY 50 60 70 80 90 100 200 210 220 230 240 250 pF1KE0 LLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVD 110 120 130 140 150 160 260 270 280 290 300 310 pF1KE0 RYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKW 170 180 190 200 210 220 320 330 340 350 360 370 pF1KE0 AHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPRVF 230 240 250 260 270 280 380 390 400 410 420 430 pF1KE0 VMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLP 290 300 310 320 330 340 440 450 460 pF1KE0 CTLASQPEGMAAKPVMEPPGLPTGAEV ::::::::::::::::::::::::::: NP_001 CTLASQPEGMAAKPVMEPPGLPTGAEV 350 360 370 >>NP_001318005 (OMIM: 609046) probable G-protein coupled (374 aa) initn: 2290 init1: 2290 opt: 2292 Z-score: 2488.0 bits: 469.3 E(85289): 7.7e-132 Smith-Waterman score: 2292; 96.9% identity (97.8% similar) in 357 aa overlap (106-462:18-374) 80 90 100 110 120 130 pF1KE0 SSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATAGQPRVTLLPTPHVSG :. . : . ::::::::::::::::: NP_001 MLTGSCGDPQKKPQVTQDSGPQSMGLEGRETAGQPRVTLLPTPHVSG 10 20 30 40 140 150 160 170 180 190 pF1KE0 LSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYY 50 60 70 80 90 100 200 210 220 230 240 250 pF1KE0 LLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVD 110 120 130 140 150 160 260 270 280 290 300 310 pF1KE0 RYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKW 170 180 190 200 210 220 320 330 340 350 360 370 pF1KE0 AHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPRVF 230 240 250 260 270 280 380 390 400 410 420 430 pF1KE0 VMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLP 290 300 310 320 330 340 440 450 460 pF1KE0 CTLASQPEGMAAKPVMEPPGLPTGAEV ::::::::::::::::::::::::::: NP_001 CTLASQPEGMAAKPVMEPPGLPTGAEV 350 360 370 >>NP_115943 (OMIM: 606923) hydroxycarboxylic acid recept (346 aa) initn: 86 init1: 53 opt: 219 Z-score: 243.5 bits: 53.9 E(85289): 8e-07 Smith-Waterman score: 219; 22.1% identity (52.6% similar) in 312 aa overlap (159-457:20-314) 130 140 150 160 170 180 pF1KE0 PTPHVSGLSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLA--T :.. . .:: .: ..::: . NP_115 MYNGSCCRIEGDTISQVMPPLLIVAFVLG-----ALGNGVALCGFCFHM 10 20 30 40 190 200 210 220 230 240 pF1KE0 RTRRPSYYYLLALTASDIIIQVVIVF-AGFLLQGAVLAR-QVPQAVVRTANILEFAANHA .: .:: ::. :...:..... . : . . :. : ..: : ... .: :.: NP_115 KTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAFGDIPCRV----GLFTLAMNRA 50 60 70 80 90 100 250 260 270 280 290 300 pF1KE0 -SVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDT :. . ....::: . :: :: . . :. .:. .: : .. : . . NP_115 GSIVFLTVVAADRYFKVVHP-HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQ 110 120 130 140 150 310 320 330 340 350 pF1KE0 DSPRTLDEVLK-----WAHCL--TVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKST .. . . . : . .:.: :..: . :. :::: . . : :. :.: NP_115 ETAVSCESFIMESANGWHDIMFQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKAT 160 170 180 190 200 210 360 370 380 390 400 410 pF1KE0 AILLGITTLFTLLWAPRVFVMLYHMYVAPVHR-DWRVHLALDVANMVAMLHTAANFGLYC ... .. .: . : : . :: ....: : :: :: .. ..... . .: NP_115 RFIMVVAIVFITCYLPSVSARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYY 220 230 240 250 260 270 420 430 440 450 460 pF1KE0 FVSKTFRATVRQVIHDAYLPCTLASQPEGMAAKPVMEPPGLPTGAEV : : .: ... :.: . : . ...: .: NP_115 FSSPSFPK-----FYNKLKICSLKPKQPGHSK--TQRPEEMPISNLGRRSCISVANSFQS 280 290 300 310 320 330 NP_115 QSDGQWDPHIVEWH 340 >>NP_001164643 (OMIM: 601470,607339,609423,613784) CX3C (355 aa) initn: 135 init1: 64 opt: 216 Z-score: 240.1 bits: 53.3 E(85289): 1.2e-06 Smith-Waterman score: 220; 23.5% identity (53.6% similar) in 319 aa overlap (136-436:8-311) 110 120 130 140 150 160 pF1KE0 DADRELRGPSEKATAGQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPV----- ....:: . ..:: : : : : NP_001 MDQFPESVTENFE--YDDLAE--ACYIGDIVVFGTVF 10 20 30 170 180 190 200 210 pF1KE0 --IYYSVLLGLGLPVSLLTAVALARLATRTRRP---SYYYLLALTASDIIIQVVIVFAGF :.:::....:: .::.. :: : ...: . ::: :. ::... ... : NP_001 LSIFYSVIFAIGLVGNLLVVFAL----TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTH 40 50 60 70 80 220 230 240 250 260 270 pF1KE0 LLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRT : . . . .:. . .. . : . .:... ....::: :. . . . NP_001 YL---INEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHG 90 100 110 120 130 140 280 290 300 310 320 330 pF1KE0 RRAIAAVLSAALLTGIPFYWWLDMWRDT---DSPRTLDEVLKWAHCLTVYFIPCGVFLVT .: .::.:.. : . . . .. : :..:.:. . . . :. . :. NP_001 VTISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLI 150 160 170 180 190 200 340 350 360 370 380 pF1KE0 NSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPR---VFVMLYHMYVAPVHRD : :. . : . . .:. ..: .. .: :.:.: .:. ..: : NP_001 MSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCD 210 220 230 240 250 260 390 400 410 420 430 440 pF1KE0 WR--VHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPCTLASQPEGMAA : ..:::.:.. ::. : : .: :... :: : . : : : NP_001 MRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFR---RYLYH-LYGKCLAVLCGRSVHV 270 280 290 300 310 320 450 460 pF1KE0 KPVMEPPGLPTGAEV NP_001 DFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL 330 340 350 >>NP_001164642 (OMIM: 601470,607339,609423,613784) CX3C (355 aa) initn: 135 init1: 64 opt: 216 Z-score: 240.1 bits: 53.3 E(85289): 1.2e-06 Smith-Waterman score: 220; 23.5% identity (53.6% similar) in 319 aa overlap (136-436:8-311) 110 120 130 140 150 160 pF1KE0 DADRELRGPSEKATAGQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPV----- ....:: . ..:: : : : : NP_001 MDQFPESVTENFE--YDDLAE--ACYIGDIVVFGTVF 10 20 30 170 180 190 200 210 pF1KE0 --IYYSVLLGLGLPVSLLTAVALARLATRTRRP---SYYYLLALTASDIIIQVVIVFAGF :.:::....:: .::.. :: : ...: . ::: :. ::... ... : NP_001 LSIFYSVIFAIGLVGNLLVVFAL----TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTH 40 50 60 70 80 220 230 240 250 260 270 pF1KE0 LLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRT : . . . .:. . .. . : . .:... ....::: :. . . . NP_001 YL---INEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHG 90 100 110 120 130 140 280 290 300 310 320 330 pF1KE0 RRAIAAVLSAALLTGIPFYWWLDMWRDT---DSPRTLDEVLKWAHCLTVYFIPCGVFLVT .: .::.:.. : . . . .. : :..:.:. . . . :. . :. NP_001 VTISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLI 150 160 170 180 190 200 340 350 360 370 380 pF1KE0 NSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPR---VFVMLYHMYVAPVHRD : :. . : . . .:. ..: .. .: :.:.: .:. ..: : NP_001 MSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCD 210 220 230 240 250 260 390 400 410 420 430 440 pF1KE0 WR--VHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPCTLASQPEGMAA : ..:::.:.. ::. : : .: :... :: : . : : : NP_001 MRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFR---RYLYH-LYGKCLAVLCGRSVHV 270 280 290 300 310 320 450 460 pF1KE0 KPVMEPPGLPTGAEV NP_001 DFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL 330 340 350 >>NP_001328 (OMIM: 601470,607339,609423,613784) CX3C che (355 aa) initn: 135 init1: 64 opt: 216 Z-score: 240.1 bits: 53.3 E(85289): 1.2e-06 Smith-Waterman score: 220; 23.5% identity (53.6% similar) in 319 aa overlap (136-436:8-311) 110 120 130 140 150 160 pF1KE0 DADRELRGPSEKATAGQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPV----- ....:: . ..:: : : : : NP_001 MDQFPESVTENFE--YDDLAE--ACYIGDIVVFGTVF 10 20 30 170 180 190 200 210 pF1KE0 --IYYSVLLGLGLPVSLLTAVALARLATRTRRP---SYYYLLALTASDIIIQVVIVFAGF :.:::....:: .::.. :: : ...: . ::: :. ::... ... : NP_001 LSIFYSVIFAIGLVGNLLVVFAL----TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTH 40 50 60 70 80 220 230 240 250 260 270 pF1KE0 LLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRT : . . . .:. . .. . : . .:... ....::: :. . . . NP_001 YL---INEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHG 90 100 110 120 130 140 280 290 300 310 320 330 pF1KE0 RRAIAAVLSAALLTGIPFYWWLDMWRDT---DSPRTLDEVLKWAHCLTVYFIPCGVFLVT .: .::.:.. : . . . .. : :..:.:. . . . :. . :. NP_001 VTISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLI 150 160 170 180 190 200 340 350 360 370 380 pF1KE0 NSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPR---VFVMLYHMYVAPVHRD : :. . : . . .:. ..: .. .: :.:.: .:. ..: : NP_001 MSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCD 210 220 230 240 250 260 390 400 410 420 430 440 pF1KE0 WR--VHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPCTLASQPEGMAA : ..:::.:.. ::. : : .: :... :: : . : : : NP_001 MRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFR---RYLYH-LYGKCLAVLCGRSVHV 270 280 290 300 310 320 450 460 pF1KE0 KPVMEPPGLPTGAEV NP_001 DFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL 330 340 350 >>NP_001164645 (OMIM: 601470,607339,609423,613784) CX3C (387 aa) initn: 135 init1: 64 opt: 216 Z-score: 239.6 bits: 53.4 E(85289): 1.3e-06 Smith-Waterman score: 220; 23.5% identity (53.6% similar) in 319 aa overlap (136-436:40-343) 110 120 130 140 150 160 pF1KE0 DADRELRGPSEKATAGQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPV----- ....:: . ..:: : : : : NP_001 LADLDFRKSSLASGWRMASGAFTMDQFPESVTENFE--YDDLAE--ACYIGDIVVFGTVF 10 20 30 40 50 60 170 180 190 200 210 pF1KE0 --IYYSVLLGLGLPVSLLTAVALARLATRTRRP---SYYYLLALTASDIIIQVVIVFAGF :.:::....:: .::.. :: : ...: . ::: :. ::... ... : NP_001 LSIFYSVIFAIGLVGNLLVVFAL----TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTH 70 80 90 100 110 120 220 230 240 250 260 270 pF1KE0 LLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRT : . . . .:. . .. . : . .:... ....::: :. . . . NP_001 YL---INEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHG 130 140 150 160 170 280 290 300 310 320 330 pF1KE0 RRAIAAVLSAALLTGIPFYWWLDMWRDT---DSPRTLDEVLKWAHCLTVYFIPCGVFLVT .: .::.:.. : . . . .. : :..:.:. . . . :. . :. NP_001 VTISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLI 180 190 200 210 220 230 340 350 360 370 380 pF1KE0 NSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPR---VFVMLYHMYVAPVHRD : :. . : . . .:. ..: .. .: :.:.: .:. ..: : NP_001 MSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCD 240 250 260 270 280 290 390 400 410 420 430 440 pF1KE0 WR--VHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPCTLASQPEGMAA : ..:::.:.. ::. : : .: :... :: : . : : : NP_001 MRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFR---RYLYH-LYGKCLAVLCGRSVHV 300 310 320 330 340 350 450 460 pF1KE0 KPVMEPPGLPTGAEV NP_001 DFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL 360 370 380 >>NP_062813 (OMIM: 605773) leukotriene B4 receptor 2 [Ho (358 aa) initn: 154 init1: 117 opt: 208 Z-score: 231.4 bits: 51.7 E(85289): 3.8e-06 Smith-Waterman score: 208; 29.3% identity (53.8% similar) in 225 aa overlap (169-384:33-251) 140 150 160 170 180 190 pF1KE0 EFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRP-SYYYLL :::: . ... .:: :: . .: NP_062 VCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVL 10 20 30 40 50 60 200 210 220 230 240 250 pF1KE0 ALTASD-IIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDR :. .: .. .. .:..:: . : . :: ... . . .::: .. ::...: NP_062 HLALADGAVLLLTPLFVAFLTRQ---AWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQR 70 80 90 100 110 260 270 280 290 300 310 pF1KE0 YTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTL-DEVLKW :. .:. ::. .:: . :: :::: ..: . .::: . : NP_062 CLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAA 120 130 140 150 160 170 320 330 340 350 360 pF1KE0 AH----CLTVYFIPCGVFLVTNSAIIHRLR--RRGRSGLQPRVGKSTAILLGITTLFTLL :: ::.. .: :..: :. . ::: : : . :::. .. .:. : :: NP_062 AHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGR---LVSAIVLAFGLL 180 190 200 210 220 230 370 380 390 400 410 420 pF1KE0 WAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVI ::: : : . .: NP_062 WAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLL 240 250 260 270 280 290 >>NP_001158164 (OMIM: 605773) leukotriene B4 receptor 2 (358 aa) initn: 154 init1: 117 opt: 208 Z-score: 231.4 bits: 51.7 E(85289): 3.8e-06 Smith-Waterman score: 208; 29.3% identity (53.8% similar) in 225 aa overlap (169-384:33-251) 140 150 160 170 180 190 pF1KE0 EFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRP-SYYYLL :::: . ... .:: :: . .: NP_001 VCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVL 10 20 30 40 50 60 200 210 220 230 240 250 pF1KE0 ALTASD-IIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDR :. .: .. .. .:..:: . : . :: ... . . .::: .. ::...: NP_001 HLALADGAVLLLTPLFVAFLTRQ---AWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQR 70 80 90 100 110 260 270 280 290 300 310 pF1KE0 YTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTL-DEVLKW :. .:. ::. .:: . :: :::: ..: . .::: . : NP_001 CLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAA 120 130 140 150 160 170 320 330 340 350 360 pF1KE0 AH----CLTVYFIPCGVFLVTNSAIIHRLR--RRGRSGLQPRVGKSTAILLGITTLFTLL :: ::.. .: :..: :. . ::: : : . :::. .. .:. : :: NP_001 AHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGR---LVSAIVLAFGLL 180 190 200 210 220 230 370 380 390 400 410 420 pF1KE0 WAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVI ::: : : . .: NP_001 WAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLL 240 250 260 270 280 290 462 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:58:16 2016 done: Wed Nov 2 20:58:17 2016 Total Scan time: 6.470 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]