FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0592, 476 aa
1>>>pF1KE0592 476 - 476 aa - 476 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5199+/-0.00114; mu= 16.3655+/- 0.067
mean_var=63.8005+/-13.171, 0's: 0 Z-trim(101.7): 34 B-trim: 270 in 1/46
Lambda= 0.160569
statistics sampled from 6618 (6631) to 6618 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.204), width: 16
Scan time: 2.690
The best scores are: opt bits E(32554)
CCDS3046.1 SEC61A1 gene_id:29927|Hs108|chr3 ( 476) 3083 723.4 1.2e-208
CCDS7088.1 SEC61A2 gene_id:55176|Hs108|chr10 ( 476) 2958 694.5 6.5e-200
CCDS44359.1 SEC61A2 gene_id:55176|Hs108|chr10 ( 454) 2655 624.3 8.4e-179
CCDS44358.1 SEC61A2 gene_id:55176|Hs108|chr10 ( 437) 2589 609.0 3.2e-174
>>CCDS3046.1 SEC61A1 gene_id:29927|Hs108|chr3 (476 aa)
initn: 3083 init1: 3083 opt: 3083 Z-score: 3859.1 bits: 723.4 E(32554): 1.2e-208
Smith-Waterman score: 3083; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476)
10 20 30 40 50 60
pF1KE0 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA
370 380 390 400 410 420
430 440 450 460 470
pF1KE0 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
430 440 450 460 470
>>CCDS7088.1 SEC61A2 gene_id:55176|Hs108|chr10 (476 aa)
initn: 2977 init1: 2951 opt: 2958 Z-score: 3702.6 bits: 694.5 E(32554): 6.5e-200
Smith-Waterman score: 2958; 93.5% identity (99.4% similar) in 476 aa overlap (1-476:1-476)
10 20 30 40 50 60
pF1KE0 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
:.:::::::::::..:::::::::::::.:::::::::::::::::::::::::::::::
CCDS70 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS70 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS
:::::::.::::::::::::.:::::::::: ::::::::::::::::::::::::::::
CCDS70 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP
::::::::::::::::::::.::::: :::::.:::::::::::::::::::::::::::
CCDS70 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN
::::::::.:::::::::::::::::::::::::::..::::::::::::::::::::::
CCDS70 NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH
:::::::::.:::::.::.::: :.:.:.:::::.:::::::::::::::.:...:::::
CCDS70 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA
.::::.:::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS70 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTA
370 380 390 400 410 420
430 440 450 460 470
pF1KE0 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
:::::::::::::::::::::::::::::::::::::::::::::.:::.::::.:
CCDS70 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF
430 440 450 460 470
>>CCDS44359.1 SEC61A2 gene_id:55176|Hs108|chr10 (454 aa)
initn: 2800 init1: 2653 opt: 2655 Z-score: 3323.6 bits: 624.3 E(32554): 8.4e-179
Smith-Waterman score: 2755; 89.1% identity (94.7% similar) in 476 aa overlap (1-476:1-454)
10 20 30 40 50 60
pF1KE0 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
:.:::::::::::..::::::::::: ::::::::::::
CCDS44 MGIKFLEVIKPFCAVLPEIQKPERKI----------------------PLFGIMSSDSAD
10 20 30
70 80 90 100 110 120
pF1KE0 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS
:::::::.::::::::::::.:::::::::: ::::::::::::::::::::::::::::
CCDS44 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP
::::::::::::::::::::.::::: :::::.:::::::::::::::::::::::::::
CCDS44 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN
::::::::.:::::::::::::::::::::::::::..::::::::::::::::::::::
CCDS44 NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH
:::::::::.:::::.::.::: :.:.:.:::::.:::::::::::::::.:...:::::
CCDS44 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA
.::::.:::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS44 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTA
340 350 360 370 380 390
430 440 450 460 470
pF1KE0 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
:::::::::::::::::::::::::::::::::::::::::::::.:::.::::.:
CCDS44 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF
400 410 420 430 440 450
>>CCDS44358.1 SEC61A2 gene_id:55176|Hs108|chr10 (437 aa)
initn: 2589 init1: 2589 opt: 2589 Z-score: 3241.2 bits: 609.0 E(32554): 3.2e-174
Smith-Waterman score: 2589; 93.3% identity (99.3% similar) in 415 aa overlap (1-415:1-415)
10 20 30 40 50 60
pF1KE0 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
:.:::::::::::..:::::::::::::.:::::::::::::::::::::::::::::::
CCDS44 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS
:::::::.::::::::::::.:::::::::: ::::::::::::::::::::::::::::
CCDS44 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP
::::::::::::::::::::.::::: :::::.:::::::::::::::::::::::::::
CCDS44 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN
::::::::.:::::::::::::::::::::::::::..::::::::::::::::::::::
CCDS44 NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH
:::::::::.:::::.::.::: :.:.:.:::::.:::::::::::::::.:...:::::
CCDS44 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA
.::::.:::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS44 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRPKVKL
370 380 390 400 410 420
430 440 450 460 470
pF1KE0 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
CCDS44 RRWKGEGRHFTKRILFY
430
476 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:55:32 2016 done: Wed Nov 2 20:55:32 2016
Total Scan time: 2.690 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]