Result of FASTA (omim) for
pF1KE0597
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0597, 1483 aa
1>>>pF1KE0597 1483 - 1483 aa - 1483 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2943+/-0.000457; mu= 1.7702+/- 0.029
mean_var=359.6000+/-73.324, 0's: 0 Z-trim(119.9): 204 B-trim: 87 in 1/55
Lambda= 0.067634
statistics sampled from 34178 (34434) to 34178 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.404), width: 16
Scan time: 17.920
The best scores are: opt bits E(85289)
NP_115784 (OMIM: 605681) tyrosine-protein kinase B (1483) 9842 976.0 0
XP_016868262 (OMIM: 605681) PREDICTED: tyrosine-pr (1483) 9842 976.0 0
XP_016876431 (OMIM: 605680) PREDICTED: bromodomain (1047) 399 54.5 5.3e-06
XP_011534678 (OMIM: 605680) PREDICTED: bromodomain (1079) 399 54.5 5.4e-06
XP_011534676 (OMIM: 605680) PREDICTED: bromodomain (1463) 399 54.6 6.6e-06
NP_872589 (OMIM: 605680) bromodomain adjacent to z (1524) 399 54.6 6.8e-06
NP_038476 (OMIM: 605680) bromodomain adjacent to z (1556) 399 54.7 6.9e-06
NP_001276904 (OMIM: 605683) bromodomain adjacent t (2132) 301 45.2 0.0065
XP_011509353 (OMIM: 605683) PREDICTED: bromodomain (2141) 301 45.2 0.0065
NP_001316787 (OMIM: 605683) bromodomain adjacent t (2143) 301 45.2 0.0065
NP_038478 (OMIM: 605683) bromodomain adjacent to z (2168) 301 45.2 0.0066
XP_011509344 (OMIM: 605683) PREDICTED: bromodomain (2207) 301 45.2 0.0067
>>NP_115784 (OMIM: 605681) tyrosine-protein kinase BAZ1B (1483 aa)
initn: 9842 init1: 9842 opt: 9842 Z-score: 5206.6 bits: 976.0 E(85289): 0
Smith-Waterman score: 9842; 100.0% identity (100.0% similar) in 1483 aa overlap (1-1483:1-1483)
10 20 30 40 50 60
pF1KE0 MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 THKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 YYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 EQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 GLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 TLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 DNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 LAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVKFEPQVDTEAEDMIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVKFEPQVDTEAEDMIS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKAN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 LGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKER
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 LEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 EARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 EEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 LCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 EEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 PVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 THPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 THPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480
pF1KE0 HKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
:::::::::::::::::::::::::::::::::::::::::::
NP_115 HKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
1450 1460 1470 1480
>>XP_016868262 (OMIM: 605681) PREDICTED: tyrosine-protei (1483 aa)
initn: 9842 init1: 9842 opt: 9842 Z-score: 5206.6 bits: 976.0 E(85289): 0
Smith-Waterman score: 9842; 100.0% identity (100.0% similar) in 1483 aa overlap (1-1483:1-1483)
10 20 30 40 50 60
pF1KE0 MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 YYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 EQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 GLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 TLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 DNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 LAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVKFEPQVDTEAEDMIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVKFEPQVDTEAEDMIS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKAN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 LGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKER
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 LEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 EARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 EEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 LCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 EEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 PVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 THPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480
pF1KE0 HKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
:::::::::::::::::::::::::::::::::::::::::::
XP_016 HKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
1450 1460 1470 1480
>>XP_016876431 (OMIM: 605680) PREDICTED: bromodomain adj (1047 aa)
initn: 750 init1: 341 opt: 399 Z-score: 228.8 bits: 54.5 E(85289): 5.3e-06
Smith-Waterman score: 702; 27.4% identity (53.2% similar) in 789 aa overlap (664-1318:12-795)
640 650 660 670 680
pF1KE0 AVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAE----DYGELGMKLSEIPLTLHSVS
..:.:. : : .:. . : ..:
XP_016 MGVCRQAIAEEEEEVAKEQLTDADTKGCSLKSLDLDSCTLS
10 20 30 40
690 700 710 720 730 740
pF1KE0 ELVRLCLRRSDVQEESEGSDTD-------DNKDSAAFEDNEVQDEFLEKLETSEFFELTS
:..:: . : .. : .. : :.: .: . ...:: .. ..::
XP_016 EILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTP
50 60 70 80 90 100
750 760 770 780
pF1KE0 EEKLQILTALCHRILMTYSVQDHMET-----RQ------QMSAELW-KERLA----VLKE
::..:: ::: ..: :..: .: :: ...:: ::: . :.
XP_016 GEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKR
110 120 130 140 150 160
790 800 810 820 830
pF1KE0 ENDKKRAEKQKRKEMEAKNKE----NGKVENGLGKTDRKKEIVKFEPQVDTEA----EDM
...: . ..:: :: . : :: :. .. ..:. .:. ...: . ::: .::
XP_016 KEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESK-DTEQKELDQDM
170 180 190 200 210 220
840 850 860 870 880
pF1KE0 I--------SAVKSRRLLAIQAK-KEREIQEREMKVKLE--RQAEEERIRKHKAAAEKAF
. : ..:: : :: ::. : : ::: ..... :: .
XP_016 VTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKEL
230 240 250 260 270 280
890 900 910 920 930 940
pF1KE0 QEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEK---GWVHDSIDYRFNHHCKDH
: : .: :.: :: . :::.: . .::::::. : ..: . : . ...
XP_016 LEKIQSAIACTNIFPLGRDRMYRRYWIFPS-IPGLFIEEDYSGLTEDMLLPRPSSF-QNN
290 300 310 320 330
950 960 970 980 990 1000
pF1KE0 TVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELL
. : : . .. . .....: : ..: . .:. : . : : . .: ..::.:.
XP_016 VQSQDPQVSTKTGEPLMSESTS-NIDQGP-RDHSVQLPKPVHKPNRWCFYSSCEQLDQLI
340 350 360 370 380 390
1010 1020 1030 1040
pF1KE0 NCLHPQGIRESQLKERLEKRYQDIIHSI--------HLARKPNLGLKSC----------D
. :. .: ::: ::: : .. . : .. :.. ::. : :
XP_016 EALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYD
400 410 420 430 440 450
1050 1060 1070 1080
pF1KE0 GNQ-----ELLNFLRSDLIEVATRLQKGGLGYVEET------SEFEA---RVISLEK---
.: .: ::. :... :. .: :: .. : : .:. ...: :.
XP_016 PSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKEN
460 470 480 490 500 510
1090 1100 1110 1120 1130
pF1KE0 --LKDFGECVIALQAS-----VIKKFLQGFMA--PKQKRRKLQSEDSAKTE---------
.: .: : .. . ..: : :. . :. . .. .:...
XP_016 GIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALF
520 530 540 550 560 570
1140 1150 1160 1170 1180
pF1KE0 EVDE--EKKMVEEAKVAS--------ALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMS
.... :..... :: .:..:. .. . ..:.. . :. :: . :. :
XP_016 QIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKS
580 590 600 610 620 630
1190 1200 1210 1220 1230
pF1KE0 AENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPAT-ARR-N
:::::.:::::. ....::: :... : .:.:: : ::.:.: :: :.: .:: .
XP_016 ILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLS
640 650 660 670 680 690
1240 1250 1260 1270 1280
pF1KE0 SRGRNYTEESAS-EDS---EDDESDEEEEEEEEEEEE-----------EDYEVA-GLRLR
:: : : . . ::: :::: : .::: . :::: :. ::. : :
XP_016 SRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGR
700 710 720 730 740 750
1290 1300 1310 1320 1330
pF1KE0 PRKTI----RGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSR
:. . ::: : . . ..::. : ...: ::
XP_016 PQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTE
760 770 780 790 800 810
1340 1350 1360 1370 1380 1390
pF1KE0 RQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYR
XP_016 TKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSS
820 830 840 850 860 870
>>XP_011534678 (OMIM: 605680) PREDICTED: bromodomain adj (1079 aa)
initn: 750 init1: 341 opt: 399 Z-score: 228.6 bits: 54.5 E(85289): 5.4e-06
Smith-Waterman score: 699; 27.5% identity (53.4% similar) in 774 aa overlap (675-1318:59-827)
650 660 670 680 690 700
pF1KE0 KGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEE
: .:. . : ..::..:: . : ..
XP_011 TEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVT
30 40 50 60 70 80
710 720 730 740 750
pF1KE0 SEGSDTD-------DNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRIL
: .. : :.: .: . ...:: .. ..:: ::..:: ::: ..:
XP_011 SANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLL
90 100 110 120 130 140
760 770 780 790 800
pF1KE0 MTYSVQDHMET-----RQ------QMSAELW-KERLA----VLKEENDKKRAEKQKRKEM
:..: .: :: ...:: ::: . :....: . ..:: ::
XP_011 TLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEK
150 160 170 180 190 200
810 820 830 840
pF1KE0 EAKNKE----NGKVENGLGKTDRKKEIVKFEPQVDTEA----EDMI--------SAVKSR
. : :: :. .. ..:. .:. ...: . ::: .::. : ..:
XP_011 QEKLKEDEQRNSTADISIGEEEREDFDTSIESK-DTEQKELDQDMVTEDEDDPGSHKRGR
210 220 230 240 250 260
850 860 870 880 890 900
pF1KE0 RLLAIQAK-KEREIQEREMKVKLE--RQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTP
: : :: ::. : : ::: ..... :: . : : .: :
XP_011 RGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIACTNIFP
270 280 290 300 310 320
910 920 930 940 950
pF1KE0 IGTDRNHNRYWLFSDEVPGLFIEK---GWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKA
.: :: . :::.: . .::::::. : ..: . : . .... : : . .. .
XP_011 LGRDRMYRRYWIFPS-IPGLFIEEDYSGLTEDMLLPRPSSF-QNNVQSQDPQVSTKTGEP
330 340 350 360 370 380
960 970 980 990 1000 1010
pF1KE0 NLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKE
.....: : ..: . .:. : . : : . .: ..::.:.. :. .: ::: :::
XP_011 LMSESTS-NIDQGP-RDHSVQLPKPVHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKE
390 400 410 420 430 440
1020 1030 1040 1050
pF1KE0 RLEKRYQDIIHSI--------HLARKPNLGLKSC----------DGNQ-----ELLNFLR
: .. . : .. :.. ::. : : .: .: ::
XP_011 TLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYDPSQMCAEKQLELRLR
450 460 470 480 490 500
1060 1070 1080 1090 1100
pF1KE0 SDLIEVATRLQKGGLGYVEET------SEFEA---RVISLEK-----LKDFGECVIALQA
. :... :. .: :: .. : : .:. ...: :. .: .: : ..
XP_011 DFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEI
510 520 530 540 550 560
1110 1120 1130 1140
pF1KE0 S-----VIKKFLQGFMA--PKQKRRKLQSEDSAKTE---------EVDE--EKKMVEEAK
. ..: : :. . :. . .. .:... .... :.....
XP_011 DEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPL
570 580 590 600 610 620
1150 1160 1170 1180 1190
pF1KE0 VAS--------ALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGED
:: .:..:. .. . ..:.. . :. :: . :. : :::::.:::::.
XP_011 DASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDA
630 640 650 660 670 680
1200 1210 1220 1230 1240 1250
pF1KE0 DKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPAT-ARR-NSRGRNYTEESAS-ED
....::: :... : .:.:: : ::.:.: :: :.: .:: .:: : : . . ::
XP_011 ENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVED
690 700 710 720 730 740
1260 1270 1280 1290
pF1KE0 S---EDDESDEEEEEEEEEEEE-----------EDYEVA-GLRLRPRKTI----RGKHSV
: :::: : .::: . :::: :. ::. : ::. . ::: :
XP_011 SMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSS
750 760 770 780 790 800
1300 1310 1320 1330 1340 1350
pF1KE0 IPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHK
. . ..::. : ...: ::
XP_011 SFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSH
810 820 830 840 850 860
>>XP_011534676 (OMIM: 605680) PREDICTED: bromodomain adj (1463 aa)
initn: 881 init1: 341 opt: 399 Z-score: 227.0 bits: 54.6 E(85289): 6.6e-06
Smith-Waterman score: 832; 26.6% identity (52.1% similar) in 1169 aa overlap (345-1318:62-1211)
320 330 340 350 360 370
pF1KE0 RKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMS
:..: . ...: .:.. ... : .
XP_011 EIFRHYELQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGKKKDA
40 50 60 70 80 90
380 390 400 410 420
pF1KE0 PNKLHTNFHIPKKGPPAKKPGKHSDKPLKAK--GRSKGILNGQKSTGNSKS---PKKGLK
. : .... :.:: : . .:: .: : ... .: :. :. :.
XP_011 IDPLLFKYKVQ----PTKKE-LHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGV-
100 110 120 130 140
430 440 450 460 470 480
pF1KE0 TPKTKMKQMTLLDMAKGTQKMTRA-PRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDR
:.: .: . . : .. : . . .. .. :: .: :. . ..
XP_011 ---IKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIH-ISQEDNVANK
150 160 170 180 190 200
490 500 510 520 530 540
pF1KE0 EDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLK
. : : . .. .::..:. : : .: ... . :: ::. . ..:...: ::
XP_011 QTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK-EKEDKEKKREELK
210 220 230 240 250 260
550 560 570 580 590
pF1KE0 K--KREELKKKL-KEKAKERREKEMLERLEKQKR------------YEDQELTG-KNLPA
: ..:.:::: ::. : .:::: :.:...:: ::.: :.::
XP_011 KIVEEERLKKKEEKERLKVEREKER-EKLREEKRKYVEYLKQWSKPREDMECDDLKELPE
270 280 290 300 310
600 610 620 630 640
pF1KE0 FRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYP--ITAVSLMEAL-SADKGG--
: : :: .:::. ::.:::. .. :. . ..: .: : ::: . :. :
XP_011 PTPVKT--RLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPL
320 330 340 350 360 370
650 660 670
pF1KE0 ----FLYLNRVLVI--------------------LLQTLLQDE------------IAEDY
:..:. .. : ..: .: .: .
XP_011 CELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAW
380 390 400 410 420 430
680 690 700 710 720
pF1KE0 GEL--GMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTD-------DNKDSAAFEDN
.: : .:. . : ..::..:: . : .. : .. : :.: .:
XP_011 PQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELR
440 450 460 470 480 490
730 740 750 760 770
pF1KE0 EVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMET-----RQ------Q
. ...:: .. ..:: ::..:: ::: ..: :..: .: :: .
XP_011 LSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRE
500 510 520 530 540 550
780 790 800 810 820
pF1KE0 MSAELW-KERLA----VLKEENDKKRAEKQKRKEMEAKNKE----NGKVENGLGKTDRKK
..:: ::: . :....: . ..:: :: . : :: :. .. ..:. .:.
XP_011 LKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEERED
560 570 580 590 600 610
830 840 850 860
pF1KE0 EIVKFEPQVDTEA----EDMI--------SAVKSRRLLAIQAK-KEREIQEREMKVKLE-
...: . ::: .::. : ..:: : :: ::. : :
XP_011 FDTSIESK-DTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREP
620 630 640 650 660 670
870 880 890 900 910 920
pF1KE0 -RQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEK-
::: ..... :: . : : .: :.: :: . :::.: . .::::::.
XP_011 LTADEEEALKQEHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPS-IPGLFIEED
680 690 700 710 720 730
930 940 950 960 970 980
pF1KE0 --GWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTP
: ..: . : . .... : : . .. . .....: : ..: . .:. :
XP_011 YSGLTEDMLLPRPSSF-QNNVQSQDPQVSTKTGEPLMSESTS-NIDQGP-RDHSVQLPKP
740 750 760 770 780 790
990 1000 1010 1020 1030
pF1KE0 KQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSI--------HLAR
. : : . .: ..::.:.. :. .: ::: ::: : .. . : .. :..
XP_011 VHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSD
800 810 820 830 840 850
1040 1050 1060 1070
pF1KE0 KPNLGLKSC----------DGNQ-----ELLNFLRSDLIEVATRLQKGGLGYVEET----
::. : : .: .: ::. :... :. .: :: .. :
XP_011 KPQPDSKPTYSRGRSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHI
860 870 880 890 900 910
1080 1090 1100 1110 1120
pF1KE0 --SEFEA---RVISLEK-----LKDFGECV----IALQASVI-KKFLQGFMA--PKQKRR
: .:. ...: :. .: .: : : :..:: : : :. . :.
XP_011 WRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVST
920 930 940 950 960 970
1130 1140 1150 1160
pF1KE0 KLQSEDSAKTE---------EVDE--EKKMVEEAKVAS--------ALEKWKTAIREAQT
. .. .:... .... :..... :: .:..:. .. . .
XP_011 NASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSAS
980 990 1000 1010 1020 1030
1170 1180 1190 1200 1210 1220
pF1KE0 FSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEV
.:.. . :. :: . :. : :::::.:::::. ....::: :... : .:.:: : :
XP_011 LSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTV
1040 1050 1060 1070 1080 1090
1230 1240 1250 1260 1270
pF1KE0 PDGEWQCPACQPAT-ARR-NSRGRNYTEESAS-EDS---EDDESDEEEEEEEEEEEE---
:.:.: :: :.: .:: .:: : : . . ::: :::: : .::: . ::::
XP_011 PEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEV
1100 1110 1120 1130 1140 1150
1280 1290 1300 1310
pF1KE0 --------EDYEVA-GLRLRPRKTI----RGKHSVIPPAARSGRRPGKKPHSTRRSQPKA
:. ::. : ::. . ::: : . . ..::. : ...: ::
XP_011 EQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKT
1160 1170 1180 1190 1200 1210
1320 1330 1340 1350 1360 1370
pF1KE0 PPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDV
XP_011 TVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSAN
1220 1230 1240 1250 1260 1270
>>NP_872589 (OMIM: 605680) bromodomain adjacent to zinc (1524 aa)
initn: 884 init1: 341 opt: 399 Z-score: 226.8 bits: 54.6 E(85289): 6.8e-06
Smith-Waterman score: 894; 27.4% identity (53.4% similar) in 1137 aa overlap (345-1318:155-1272)
320 330 340 350 360 370
pF1KE0 RKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMS
:..: . ...: .:.. ... : .
NP_872 IRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGKKKDA
130 140 150 160 170 180
380 390 400 410 420
pF1KE0 PNKLHTNFHIPKKGPPAKKPGKHSDKPLKAK--GRSKGILNGQKSTGNSKS---PKKGLK
. : .... :.:: : . .:: .: : ... .: :. :. :.
NP_872 IDPLLFKYKVQ----PTKKE-LHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGV-
190 200 210 220 230
430 440 450 460 470 480
pF1KE0 TPKTKMKQMTLLDMAKGTQKMTRA-PRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDR
:.: .: . . : .. : . . .. .. :: .: :. . ..
NP_872 ---IKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIH-ISQEDNVANK
240 250 260 270 280 290
490 500 510 520 530 540
pF1KE0 EDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLK
. : : . .. .::..:. : : .: ... . :: ::. . ..:...: ::
NP_872 QTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK-EKEDKEKKREELK
300 310 320 330 340 350
550 560 570 580 590
pF1KE0 K--KREELKKKL-KEKAKERREKEMLERLEKQKR------------YEDQELTG-KNLPA
: ..:.:::: ::. : .:::: :.:...:: ::.: :.::
NP_872 KIVEEERLKKKEEKERLKVEREKER-EKLREEKRKYVEYLKQWSKPREDMECDDLKELPE
360 370 380 390 400 410
600 610 620 630 640
pF1KE0 FRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYP--ITAVSLMEAL-SADKGGFL
: : :: .:::. ::.:::. .. :. . ..: .: : ::: . :. : :
NP_872 PTPVKT--RLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPL
420 430 440 450 460 470
650 660 670 680 690 700
pF1KE0 --YLNRVLVILLQTLLQDE--IAE----DYGELGMKLSEIPLTLHSVSELVRLCLRRSDV
: :. ..:.. ..: .:. : : .:. . : ..::..:: . : .
NP_872 CELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKGCSLKSLDLDSCTLSEILRLHILASGA
480 490 500 510 520 530
710 720 730 740 750
pF1KE0 QEESEGSDTD-------DNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCH
. : .. : :.: .: . ...:: .. ..:: ::..:: :::
NP_872 DVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCG
540 550 560 570 580 590
760 770 780 790
pF1KE0 RILMTYSVQDHMET-----RQ------QMSAELW-KERLA----VLKEENDKKRAEKQKR
..: :..: .: :: ...:: ::: . :....: . ..::
NP_872 KLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKM
600 610 620 630 640 650
800 810 820 830 840
pF1KE0 KEMEAKNKE----NGKVENGLGKTDRKKEIVKFEPQVDTEA----EDMI--------SAV
:: . : :: :. .. ..:. .:. ...: . ::: .::. :
NP_872 KEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESK-DTEQKELDQDMVTEDEDDPGSHK
660 670 680 690 700
850 860 870 880 890
pF1KE0 KSRRLLAIQAK-KEREIQEREMKVKLE--RQAEEERIRKHKAAAEKAFQEGIAKAKLVMR
..:: : :: ::. : : ::: ..... :: . : : .:
NP_872 RGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIACTN
710 720 730 740 750 760
900 910 920 930 940 950
pF1KE0 RTPIGTDRNHNRYWLFSDEVPGLFIEK---GWVHDSIDYRFNHHCKDHTVSGDEDYCPRS
:.: :: . :::.: . .::::::. : ..: . : . .... : : . ..
NP_872 IFPLGRDRMYRRYWIFPS-IPGLFIEEDYSGLTEDMLLPRPSSF-QNNVQSQDPQVSTKT
770 780 790 800 810 820
960 970 980 990 1000 1010
pF1KE0 KKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQ
. .....: : ..: . .:. : . : : . .: ..::.:.. :. .: :::
NP_872 GEPLMSESTS-NIDQGP-RDHSVQLPKPVHKPNRWCFYSSCEQLDQLIEALNSRGHRESA
830 840 850 860 870 880
1020 1030 1040 1050
pF1KE0 LKERLEKRYQDIIHSI--------HLARKPNLGLKSC----------DGNQ-----ELLN
::: : .. . : .. :.. ::. : : .: .:
NP_872 LKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYDPSQMCAEKQLEL
890 900 910 920 930 940
1060 1070 1080 1090
pF1KE0 FLRSDLIEVATRLQKGGLGYVEET------SEFEA---RVISLEK-----LKDFGECV--
::. :... :. .: :: .. : : .:. ...: :. .: .: :
NP_872 RLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEE
950 960 970 980 990 1000
1100 1110 1120 1130 1140
pF1KE0 --IALQASVI-KKFLQGFMA--PKQKRRKLQSEDSAKTE---------EVDE--EKKMVE
: :..:: : : :. . :. . .. .:... .... :.....
NP_872 MEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLK
1010 1020 1030 1040 1050 1060
1150 1160 1170 1180 1190
pF1KE0 EAKVAS--------ALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKK
:: .:..:. .. . ..:.. . :. :: . :. : :::::.::::
NP_872 APLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKK
1070 1080 1090 1100 1110 1120
1200 1210 1220 1230 1240 1250
pF1KE0 GEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPAT-ARR-NSRGRNYTEESAS
:. ....::: :... : .:.:: : ::.:.: :: :.: .:: .:: : : . .
NP_872 GDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDED
1130 1140 1150 1160 1170 1180
1260 1270 1280 1290
pF1KE0 -EDS---EDDESDEEEEEEEEEEEE-----------EDYEVA-GLRLRPRKTI----RGK
::: :::: : .::: . :::: :. ::. : ::. . :::
NP_872 VEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGK
1190 1200 1210 1220 1230 1240
1300 1310 1320 1330 1340 1350
pF1KE0 HSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEI
: . . ..::. : ...: ::
NP_872 LSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTR
1250 1260 1270 1280 1290 1300
>>NP_038476 (OMIM: 605680) bromodomain adjacent to zinc (1556 aa)
initn: 884 init1: 341 opt: 399 Z-score: 226.6 bits: 54.7 E(85289): 6.9e-06
Smith-Waterman score: 832; 26.6% identity (52.1% similar) in 1169 aa overlap (345-1318:155-1304)
320 330 340 350 360 370
pF1KE0 RKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMS
:..: . ...: .:.. ... : .
NP_038 IRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGKKKDA
130 140 150 160 170 180
380 390 400 410 420
pF1KE0 PNKLHTNFHIPKKGPPAKKPGKHSDKPLKAK--GRSKGILNGQKSTGNSKS---PKKGLK
. : .... :.:: : . .:: .: : ... .: :. :. :.
NP_038 IDPLLFKYKVQ----PTKKE-LHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGV-
190 200 210 220 230
430 440 450 460 470 480
pF1KE0 TPKTKMKQMTLLDMAKGTQKMTRA-PRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDR
:.: .: . . : .. : . . .. .. :: .: :. . ..
NP_038 ---IKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIH-ISQEDNVANK
240 250 260 270 280 290
490 500 510 520 530 540
pF1KE0 EDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLK
. : : . .. .::..:. : : .: ... . :: ::. . ..:...: ::
NP_038 QTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK-EKEDKEKKREELK
300 310 320 330 340 350
550 560 570 580 590
pF1KE0 K--KREELKKKL-KEKAKERREKEMLERLEKQKR------------YEDQELTG-KNLPA
: ..:.:::: ::. : .:::: :.:...:: ::.: :.::
NP_038 KIVEEERLKKKEEKERLKVEREKER-EKLREEKRKYVEYLKQWSKPREDMECDDLKELPE
360 370 380 390 400 410
600 610 620 630 640
pF1KE0 FRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYP--ITAVSLMEAL-SADKGG--
: : :: .:::. ::.:::. .. :. . ..: .: : ::: . :. :
NP_038 PTPVKT--RLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPL
420 430 440 450 460 470
650 660 670
pF1KE0 ----FLYLNRVLVI--------------------LLQTLLQDE------------IAEDY
:..:. .. : ..: .: .: .
NP_038 CELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAW
480 490 500 510 520 530
680 690 700 710 720
pF1KE0 GEL--GMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTD-------DNKDSAAFEDN
.: : .:. . : ..::..:: . : .. : .. : :.: .:
NP_038 PQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELR
540 550 560 570 580 590
730 740 750 760 770
pF1KE0 EVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMET-----RQ------Q
. ...:: .. ..:: ::..:: ::: ..: :..: .: :: .
NP_038 LSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRE
600 610 620 630 640 650
780 790 800 810 820
pF1KE0 MSAELW-KERLA----VLKEENDKKRAEKQKRKEMEAKNKE----NGKVENGLGKTDRKK
..:: ::: . :....: . ..:: :: . : :: :. .. ..:. .:.
NP_038 LKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEERED
660 670 680 690 700 710
830 840 850 860
pF1KE0 EIVKFEPQVDTEA----EDMI--------SAVKSRRLLAIQAK-KEREIQEREMKVKLE-
...: . ::: .::. : ..:: : :: ::. : :
NP_038 FDTSIESK-DTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREP
720 730 740 750 760
870 880 890 900 910 920
pF1KE0 -RQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEK-
::: ..... :: . : : .: :.: :: . :::.: . .::::::.
NP_038 LTADEEEALKQEHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPS-IPGLFIEED
770 780 790 800 810 820
930 940 950 960 970 980
pF1KE0 --GWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTP
: ..: . : . .... : : . .. . .....: : ..: . .:. :
NP_038 YSGLTEDMLLPRPSSF-QNNVQSQDPQVSTKTGEPLMSESTS-NIDQGP-RDHSVQLPKP
830 840 850 860 870 880
990 1000 1010 1020 1030
pF1KE0 KQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSI--------HLAR
. : : . .: ..::.:.. :. .: ::: ::: : .. . : .. :..
NP_038 VHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSD
890 900 910 920 930 940
1040 1050 1060 1070
pF1KE0 KPNLGLKSC----------DGNQ-----ELLNFLRSDLIEVATRLQKGGLGYVEET----
::. : : .: .: ::. :... :. .: :: .. :
NP_038 KPQPDSKPTYSRGRSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHI
950 960 970 980 990 1000
1080 1090 1100 1110 1120
pF1KE0 --SEFEA---RVISLEK-----LKDFGECV----IALQASVI-KKFLQGFMA--PKQKRR
: .:. ...: :. .: .: : : :..:: : : :. . :.
NP_038 WRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVST
1010 1020 1030 1040 1050 1060
1130 1140 1150 1160
pF1KE0 KLQSEDSAKTE---------EVDE--EKKMVEEAKVAS--------ALEKWKTAIREAQT
. .. .:... .... :..... :: .:..:. .. . .
NP_038 NASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSAS
1070 1080 1090 1100 1110 1120
1170 1180 1190 1200 1210 1220
pF1KE0 FSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEV
.:.. . :. :: . :. : :::::.:::::. ....::: :... : .:.:: : :
NP_038 LSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTV
1130 1140 1150 1160 1170 1180
1230 1240 1250 1260 1270
pF1KE0 PDGEWQCPACQPAT-ARR-NSRGRNYTEESAS-EDS---EDDESDEEEEEEEEEEEE---
:.:.: :: :.: .:: .:: : : . . ::: :::: : .::: . ::::
NP_038 PEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEV
1190 1200 1210 1220 1230 1240
1280 1290 1300 1310
pF1KE0 --------EDYEVA-GLRLRPRKTI----RGKHSVIPPAARSGRRPGKKPHSTRRSQPKA
:. ::. : ::. . ::: : . . ..::. : ...: ::
NP_038 EQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKT
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KE0 PPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDV
NP_038 TVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSAN
1310 1320 1330 1340 1350 1360
>>NP_001276904 (OMIM: 605683) bromodomain adjacent to zi (2132 aa)
initn: 456 init1: 285 opt: 301 Z-score: 173.3 bits: 45.2 E(85289): 0.0065
Smith-Waterman score: 498; 24.7% identity (55.3% similar) in 503 aa overlap (947-1425:1640-2110)
920 930 940 950 960 970
pF1KE0 DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATE
: .:. :...::. .. :.... . ..
NP_001 PFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSESPVPQNEKATSAQPAAVEVAK--PVD
1610 1620 1630 1640 1650 1660
980 990 1000 1010 1020 1030
pF1KE0 VAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLAR
:.. : :. . ..: ::. :: .::::. :.....: . : : . :
NP_001 FPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQK-HLDYITQACLKN
1670 1680 1690 1700 1710 1720
1040 1050 1060 1070 1080
pF1KE0 KPNLGLKSCDGNQELLNFLRSDLIE---VATRLQKGGLGYVEETSEFEARVISL------
: .... . :.: : . :..: : . .. :. .... ..: :: :
NP_001 K-DVAIIELNENEE--NQVTRDIVENWSVEEQAMEMDLSVLQQVEDLERRVASASLQVKG
1730 1740 1750 1760 1770 1780
1090 1100 1110 1120 1130
pF1KE0 ----EKLKDFGECVIALQASVIK--KFLQG-FMAPKQ------KRRKLQSEDSAKTEEVD
: .. . : . : : : .: : . . .:.. . : : :. .:
NP_001 WMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAHALERKSDNPLDIAVTRLAD
1790 1800 1810 1820 1830 1840
1140 1150 1160 1170 1180 1190
pF1KE0 EEKKMVE--EAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRK
:... . : .: .:. :. :. ::.. ... . . .:. : :. : .. :..:::
NP_001 LERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRK
1850 1860 1870 1880 1890 1900
1200 1210 1220 1230 1240 1250
pF1KE0 KGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASE
... :.::: :.:. : .: :: . .:::.: :::: :. ... . . ..
NP_001 GDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC---IAKASGQTLKIKKLHVKG
1910 1920 1930 1940 1950 1960
1260 1270 1280 1290 1300 1310
pF1KE0 DSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHST
. .. . .. . :.:: .. :. ::.... ::
NP_001 KKTNESKKGKKVTLTGDTEDEDSASTSSSLK-----RGNKDL------------KK----
1970 1980 1990
1320 1330 1340 1350 1360 1370
pF1KE0 RRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDE
:.. . .. .. .: ..:. .: .: .: : :: .. .. .::: ::.
NP_001 -RKMEENTSINLSK-QESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKL
2000 2010 2020 2030 2040 2050
1380 1390 1400 1410 1420 1430
pF1KE0 AEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKT
. : :: .::::.:...: : :.: ... : :.. :: : :..: : .
NP_001 VPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNM
2060 2070 2080 2090 2100 2110
1440 1450 1460 1470 1480
pF1KE0 EQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
NP_001 RKYFEKKWTDTFKVS
2120 2130
>>XP_011509353 (OMIM: 605683) PREDICTED: bromodomain adj (2141 aa)
initn: 456 init1: 285 opt: 301 Z-score: 173.2 bits: 45.2 E(85289): 0.0065
Smith-Waterman score: 498; 24.7% identity (55.3% similar) in 503 aa overlap (947-1425:1649-2119)
920 930 940 950 960 970
pF1KE0 DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATE
: .:. :...::. .. :.... . ..
XP_011 PFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSESPVPQNEKATSAQPAAVEVAK--PVD
1620 1630 1640 1650 1660 1670
980 990 1000 1010 1020 1030
pF1KE0 VAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLAR
:.. : :. . ..: ::. :: .::::. :.....: . : : . :
XP_011 FPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQK-HLDYITQACLKN
1680 1690 1700 1710 1720 1730
1040 1050 1060 1070 1080
pF1KE0 KPNLGLKSCDGNQELLNFLRSDLIE---VATRLQKGGLGYVEETSEFEARVISL------
: .... . :.: : . :..: : . .. :. .... ..: :: :
XP_011 K-DVAIIELNENEE--NQVTRDIVENWSVEEQAMEMDLSVLQQVEDLERRVASASLQVKG
1740 1750 1760 1770 1780 1790
1090 1100 1110 1120 1130
pF1KE0 ----EKLKDFGECVIALQASVIK--KFLQG-FMAPKQ------KRRKLQSEDSAKTEEVD
: .. . : . : : : .: : . . .:.. . : : :. .:
XP_011 WMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAHALERKSDNPLDIAVTRLAD
1800 1810 1820 1830 1840 1850
1140 1150 1160 1170 1180 1190
pF1KE0 EEKKMVE--EAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRK
:... . : .: .:. :. :. ::.. ... . . .:. : :. : .. :..:::
XP_011 LERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRK
1860 1870 1880 1890 1900 1910
1200 1210 1220 1230 1240 1250
pF1KE0 KGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASE
... :.::: :.:. : .: :: . .:::.: :::: :. ... . . ..
XP_011 GDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC---IAKASGQTLKIKKLHVKG
1920 1930 1940 1950 1960
1260 1270 1280 1290 1300 1310
pF1KE0 DSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHST
. .. . .. . :.:: .. :. ::.... ::
XP_011 KKTNESKKGKKVTLTGDTEDEDSASTSSSLK-----RGNKDL------------KK----
1970 1980 1990 2000
1320 1330 1340 1350 1360 1370
pF1KE0 RRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDE
:.. . .. .. .: ..:. .: .: .: : :: .. .. .::: ::.
XP_011 -RKMEENTSINLSK-QESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKL
2010 2020 2030 2040 2050 2060
1380 1390 1400 1410 1420 1430
pF1KE0 AEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKT
. : :: .::::.:...: : :.: ... : :.. :: : :..: : .
XP_011 VPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNM
2070 2080 2090 2100 2110 2120
1440 1450 1460 1470 1480
pF1KE0 EQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
XP_011 RKYFEKKWTDTFKVS
2130 2140
>>NP_001316787 (OMIM: 605683) bromodomain adjacent to zi (2143 aa)
initn: 456 init1: 285 opt: 301 Z-score: 173.2 bits: 45.2 E(85289): 0.0065
Smith-Waterman score: 498; 24.7% identity (55.3% similar) in 503 aa overlap (947-1425:1651-2121)
920 930 940 950 960 970
pF1KE0 DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATE
: .:. :...::. .. :.... . ..
NP_001 PFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSESPVPQNEKATSAQPAAVEVAK--PVD
1630 1640 1650 1660 1670
980 990 1000 1010 1020 1030
pF1KE0 VAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLAR
:.. : :. . ..: ::. :: .::::. :.....: . : : . :
NP_001 FPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQK-HLDYITQACLKN
1680 1690 1700 1710 1720 1730
1040 1050 1060 1070 1080
pF1KE0 KPNLGLKSCDGNQELLNFLRSDLIE---VATRLQKGGLGYVEETSEFEARVISL------
: .... . :.: : . :..: : . .. :. .... ..: :: :
NP_001 K-DVAIIELNENEE--NQVTRDIVENWSVEEQAMEMDLSVLQQVEDLERRVASASLQVKG
1740 1750 1760 1770 1780 1790
1090 1100 1110 1120 1130
pF1KE0 ----EKLKDFGECVIALQASVIK--KFLQG-FMAPKQ------KRRKLQSEDSAKTEEVD
: .. . : . : : : .: : . . .:.. . : : :. .:
NP_001 WMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAHALERKSDNPLDIAVTRLAD
1800 1810 1820 1830 1840 1850
1140 1150 1160 1170 1180 1190
pF1KE0 EEKKMVE--EAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRK
:... . : .: .:. :. :. ::.. ... . . .:. : :. : .. :..:::
NP_001 LERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRK
1860 1870 1880 1890 1900 1910
1200 1210 1220 1230 1240 1250
pF1KE0 KGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASE
... :.::: :.:. : .: :: . .:::.: :::: :. ... . . ..
NP_001 GDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC---IAKASGQTLKIKKLHVKG
1920 1930 1940 1950 1960 1970
1260 1270 1280 1290 1300 1310
pF1KE0 DSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHST
. .. . .. . :.:: .. :. ::.... ::
NP_001 KKTNESKKGKKVTLTGDTEDEDSASTSSSLK-----RGNKDL------------KK----
1980 1990 2000 2010
1320 1330 1340 1350 1360 1370
pF1KE0 RRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDE
:.. . .. .. .: ..:. .: .: .: : :: .. .. .::: ::.
NP_001 -RKMEENTSINLSK-QESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKL
2020 2030 2040 2050 2060
1380 1390 1400 1410 1420 1430
pF1KE0 AEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKT
. : :: .::::.:...: : :.: ... : :.. :: : :..: : .
NP_001 VPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNM
2070 2080 2090 2100 2110 2120
1440 1450 1460 1470 1480
pF1KE0 EQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
NP_001 RKYFEKKWTDTFKVS
2130 2140
1483 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:05:01 2016 done: Sat Nov 5 19:05:04 2016
Total Scan time: 17.920 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]